James T Hodgkinson

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 10

Top Venues

RSC medicinal chemistry

ACS medicinal chemistry letters

Beilstein journal of organic chemistry

RSC chemical biology

University of Leicester

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Leicester Oct 02 2016

United Kingdom

Lecturer :: Chemistry

Publications

Joshua P Smalley, Shaun M Cowley, James T Hodgkinson
MDM2 Antagonist Idasanutlin Reduces HDAC1/2 Abundance and Corepressor Partners but Not HDAC3. ACS medicinal chemistry letters 15 (1) (2023)
Urvashi Patel, Joshua P Smalley, James T Hodgkinson
PROTAC chemical probes for histone deacetylase enzymes. RSC chemical biology 4 (9) (2023)
Joshua P Smalley, Shaun M Cowley, James T Hodgkinson
MDM2 Antagonist Idasanutlin Reduces HDAC1/2 Abundance and Corepressor Partners but Not HDAC3. ACS medicinal chemistry letters 15 (1) (2023)
Jasmine M Cross, Megan E Coulson, Joshua P Smalley, Wiktoria A Pytel, Ozair Ismail, Justin S Trory, Shaun M Cowley, James T Hodgkinson
A 'click' chemistry approach to novel entinostat (MS-275) based class I histone deacetylase proteolysis targeting chimeras. RSC medicinal chemistry 13 (12) (2022)
India M Baker, Joshua P Smalley, Khadija A Sabat, James T Hodgkinson, Shaun M Cowley
Comprehensive Transcriptomic Analysis of Novel Class I HDAC Proteolysis Targeting Chimeras (PROTACs). Biochemistry (2022)
Jasmine M Cross, Megan E Coulson, Joshua P Smalley, Wiktoria A Pytel, Ozair Ismail, Justin S Trory, Shaun M Cowley, James T Hodgkinson
A 'click' chemistry approach to novel entinostat (MS-275) based class I histone deacetylase proteolysis targeting chimeras. RSC medicinal chemistry 13 (12) (2022)
Joshua P Smalley, India M Baker, Wiktoria A Pytel, Li-Ying Lin, Karen J Bowman, John W R Schwabe, Shaun M Cowley, James T Hodgkinson
Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells. Journal of medicinal chemistry 65 (7) (2022)
Gregory M Williams, Vasileios Paschalis, Janice Ortega, Frederick W Muskett, James T Hodgkinson, Guo-Min Li, John W R Schwabe, Robert S Lahue
HDAC3 deacetylates the DNA mismatch repair factor MutSβ to stimulate triplet repeat expansions. Proceedings of the National Academy of Sciences of the United States of America 117 (38) (2020)
Joshua P Smalley, Grace E Adams, Christopher J Millard, Yun Song, James K S Norris, John W R Schwabe, Shaun Michael Cowley, James T Hodgkinson
PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes. Chemical communications (Cambridge, England) 56 (32) (2020)
Abed Tarapdar, James K S Norris, Oliver Sampson, Galina Mukamolova, James T Hodgkinson
The design and synthesis of an antibacterial phenothiazine-siderophore conjugate. Beilstein journal of organic chemistry 14 (2018)

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Publication Activity (10 Years)

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James T Hodgkinson