Jean-Michel Brunel (Jean Michel Brunel, Brunel Jean Michel)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 48

Top Topics

Pseudomonas Aeruginosa

Multidrug Resistant

Cystic Fibrosis

Top Venues

Antibiotics (Basel, Switzerland)

International journal of molecular sciences

Journal of medicinal chemistry

Molecules (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Clémence Rose, Rodrigo Hernán Tomas-Grau, Brenda Zabala, Patrick Pierre Michel, Jean-Michel Brunel, Rosana Chehín, Rita Raisman-Vozari, Laurent Ferrié, Bruno Figadère
C9-Functionalized Doxycycline Analogs as Drug Candidates to Prevent Pathological α-Synuclein Aggregation and Neuroinflammation in Parkinson's Disease Degeneration. ChemMedChem (2024)
Andrea Castaldi, Bich Ngan Truong, Quyen Thi Vu, Thi Hong Minh Le, Arul Marie, Gaël Le Pennec, Florent Rouvier, Jean-Michel Brunel, Arlette Longeon, Van Cuong Pham, Thi Mai Huong Doan, Marie-Lise Bourguet-Kondracki
Computational Methods Reveal a Series of Cyclic and Linear Lichenysins and Surfactins from the Vietnamese Marine Sediment-Derived Streptomyces Strain G222. Molecules (Basel, Switzerland) 29 (7) (2024)
Andrea Castaldi, Bich Ngan Truong, Quyen Thi Vu, Thi Hong Minh Le, Arul Marie, Gaël Le Pennec, Florent Rouvier, Jean-Michel Brunel, Arlette Longeon, Van Cuong Pham, Thi Mai Huong Doan, Marie-Lise Bourguet-Kondracki
Computational Methods Reveal a Series of Cyclic and Linear Lichenysins and Surfactins from the Vietnamese Marine Sediment-Derived Streptomyces Strain G222. Molecules (Basel, Switzerland) 29 (7) (2024)
Clémence Rose, Rodrigo Hernán Tomas-Grau, Brenda Zabala, Patrick Pierre Michel, Jean-Michel Brunel, Rosana Chehín, Rita Raisman-Vozari, Laurent Ferrié, Bruno Figadère
C9-Functionalized Doxycycline Analogs as Drug Candidates to Prevent Pathological α-Synuclein Aggregation and Neuroinflammation in Parkinson's Disease Degeneration. ChemMedChem 19 (12) (2024)
Andrea Castaldi, Bich Ngan Truong, Quyen Thi Vu, Thi Hong Minh Le, Arul Marie, Gaël Le Pennec, Florent Rouvier, Jean-Michel Brunel, Arlette Longeon, Van Cuong Pham, Thi Mai Huong Doan, Marie-Lise Bourguet-Kondracki
Computational Methods Reveal a Series of Cyclic and Linear Lichenysins and Surfactins from the Vietnamese Marine Sediment-Derived Streptomyces Strain G222. Molecules (Basel, Switzerland) 29 (7) (2024)
Kenneth Sue, Melissa M Cadelis, Florent Rouvier, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
Antimicrobial Indole-3-Carboxamido-Polyamine Conjugates Target Bacterial Membranes and Are Antibiotic Potentiators. Biomolecules 14 (3) (2024)
Clémence Rose, Rodrigo Hernán Tomas-Grau, Brenda Zabala, Patrick Pierre Michel, Jean-Michel Brunel, Rosana Chehín, Rita Raisman-Vozari, Laurent Ferrié, Bruno Figadère
C9-Functionalized Doxycycline Analogs as Drug Candidates to Prevent Pathological α-Synuclein Aggregation and Neuroinflammation in Parkinson's Disease Degeneration. ChemMedChem 19 (12) (2024)
Kenneth Sue, Melissa M Cadelis, Florent Rouvier, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
Antimicrobial Indole-3-Carboxamido-Polyamine Conjugates Target Bacterial Membranes and Are Antibiotic Potentiators. Biomolecules 14 (3) (2024)
Kenneth Sue, Melissa M Cadelis, Florent Rouvier, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
Antimicrobial Indole-3-Carboxamido-Polyamine Conjugates Target Bacterial Membranes and Are Antibiotic Potentiators. Biomolecules 14 (3) (2024)
Dan Chen, Melissa M Cadelis, Florent Rouvier, Thomas Troia, Liam R Edmeades, Kyle Fraser, Evangelene S Gill, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
α,ω-Diacyl-Substituted Analogues of Natural and Unnatural Polyamines: Identification of Potent Bactericides That Selectively Target Bacterial Membranes. International journal of molecular sciences 24 (6) (2023)
Jinane Tabcheh, Julia Vergalli, Anne Davin-Régli, Noha Ghanem, Jean Marie Pagès, Charbel Al-Bayssari, Jean-Michel Brunel
Rejuvenating the Activity of Usual Antibiotics on Resistant Gram-Negative Bacteria: Recent Issues and Perspectives. International journal of molecular sciences 24 (2) (2023)
Dan Chen, Melissa M Cadelis, Florent Rouvier, Thomas Troia, Liam R Edmeades, Kyle Fraser, Evangelene S Gill, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
α,ω-Diacyl-Substituted Analogues of Natural and Unnatural Polyamines: Identification of Potent Bactericides That Selectively Target Bacterial Membranes. International journal of molecular sciences 24 (6) (2023)
Kenneth Sue, Melissa M Cadelis, Thomas Troia, Florent Rouvier, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
Investigation of α,ω-Disubstituted Polyamine-Cholic Acid Conjugates Identifies Hyodeoxycholic and Chenodeoxycholic Scaffolds as Non-Toxic, Potent Antimicrobials. Antibiotics (Basel, Switzerland) 12 (2) (2023)
Melissa M Cadelis, Tim Liu, Kenneth Sue, Florent Rouvier, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
Structure-Activity Relationship Studies of Indolglyoxyl-Polyamine Conjugates as Antimicrobials and Antibiotic Potentiators. Pharmaceuticals (Basel, Switzerland) 16 (6) (2023)
Delphine Vergoz, Hung Le, Benoit Bernay, Annick Schaumann, Magalie Barreau, Flore Nilly, Florie Desriac, Ali Tahrioui, Jean-Christophe Giard, Olivier Lesouhaitier, Sylvie Chevalier, Jean-Michel Brunel, Cécile Muller, Emmanuelle Dé
Antibiofilm and Antivirulence Properties of 6-Polyaminosteroid Derivatives against Antibiotic-Resistant Bacteria. Antibiotics (Basel, Switzerland) 13 (1) (2023)
Melissa M Cadelis, Liam R Edmeades, Dan Chen, Evangelene S Gill, Kyle Fraser, Florent Rouvier, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
Investigation of Naphthyl-Polyamine Conjugates as Antimicrobials and Antibiotic Enhancers. Antibiotics (Basel, Switzerland) 12 (6) (2023)
Kenneth Sue, Melissa M Cadelis, Kerrin Hainsworth, Florent Rouvier, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
Preliminary SAR of Novel Pleuromutilin-Polyamine Conjugates. Microorganisms 11 (11) (2023)
Delphine Vergoz, Flore Nilly, Florie Desriac, Magalie Barreau, Antoine Géry, Charlie Lepetit, François Sichel, Katy Jeannot, Jean-Christophe Giard, David Garon, Sylvie Chevalier, Cécile Muller, Emmanuelle Dé, Jean-Michel Brunel
6-Polyaminosteroid Squalamine Analogues Display Antibacterial Activity against Resistant Pathogens. International journal of molecular sciences 24 (10) (2023)
Jinane Tabcheh, Julia Vergalli, Anne Davin-Régli, Noha Ghanem, Jean Marie Pagès, Charbel Al-Bayssari, Jean-Michel Brunel
Rejuvenating the Activity of Usual Antibiotics on Resistant Gram-Negative Bacteria: Recent Issues and Perspectives. International journal of molecular sciences 24 (2) (2023)
Delphine Vergoz, Hung Le, Benoit Bernay, Annick Schaumann, Magalie Barreau, Flore Nilly, Florie Desriac, Ali Tahrioui, Jean-Christophe Giard, Olivier Lesouhaitier, Sylvie Chevalier, Jean-Michel Brunel, Cécile Muller, Emmanuelle Dé
Antibiofilm and Antivirulence Properties of 6-Polyaminosteroid Derivatives against Antibiotic-Resistant Bacteria. Antibiotics (Basel, Switzerland) 13 (1) (2023)
Margot Draveny, Clémence Rose, Alexis Pinet, Laurent Ferrié, Bruno Figadère, Jean-Michel Brunel, Muriel Masi
Scope and Limitations of Exploiting the Ability of the Chemosensitizer NV716 to Enhance the Activity of Tetracycline Derivatives against Pseudomonas aeruginosa . Molecules (Basel, Switzerland) 28 (11) (2023)
Jinane Tabcheh, Julia Vergalli, Anne Davin-Régli, Noha Ghanem, Jean Marie Pagès, Charbel Al-Bayssari, Jean-Michel Brunel
Rejuvenating the Activity of Usual Antibiotics on Resistant Gram-Negative Bacteria: Recent Issues and Perspectives. International journal of molecular sciences 24 (2) (2023)
Dan Chen, Melissa M Cadelis, Florent Rouvier, Thomas Troia, Liam R Edmeades, Kyle Fraser, Evangelene S Gill, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
α,ω-Diacyl-Substituted Analogues of Natural and Unnatural Polyamines: Identification of Potent Bactericides That Selectively Target Bacterial Membranes. International journal of molecular sciences 24 (6) (2023)
Kenneth Sue, Melissa M Cadelis, Thomas Troia, Florent Rouvier, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
Investigation of α,ω-Disubstituted Polyamine-Cholic Acid Conjugates Identifies Hyodeoxycholic and Chenodeoxycholic Scaffolds as Non-Toxic, Potent Antimicrobials. Antibiotics (Basel, Switzerland) 12 (2) (2023)
Aurore Tourville, Sarah Viguier, Florencia González-Lizárraga, Rodrigo Hernán Tomas-Grau, Paola Ramirez, Jean-Michel Brunel, Mauricio Dos Santos Pereira, Elaine Del-Bel, Rosana Chehin, Laurent Ferrié, Rita Raisman-Vozari, Bruno Figadère, Patrick Pierre Michel
Rescue of Dopamine Neurons from Iron-Dependent Ferroptosis by Doxycycline and Demeclocycline and Their Non-Antibiotic Derivatives. Antioxidants (Basel, Switzerland) 12 (3) (2023)
Aurore Tourville, Sarah Viguier, Florencia González-Lizárraga, Rodrigo Hernán Tomas-Grau, Paola Ramirez, Jean-Michel Brunel, Mauricio Dos Santos Pereira, Elaine Del-Bel, Rosana Chehin, Laurent Ferrié, Rita Raisman-Vozari, Bruno Figadère, Patrick Pierre Michel
Rescue of Dopamine Neurons from Iron-Dependent Ferroptosis by Doxycycline and Demeclocycline and Their Non-Antibiotic Derivatives. Antioxidants (Basel, Switzerland) 12 (3) (2023)
Kenneth Sue, Melissa M Cadelis, Evangelene S Gill, Florent Rouvier, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
Indole-3-Acetamido-Polyamines as Antimicrobial Agents and Antibiotic Adjuvants. Biomolecules 13 (8) (2023)
Jinane Tabcheh, Julia Vergalli, Anne Davin-Régli, Noha Ghanem, Jean Marie Pagès, Charbel Al-Bayssari, Jean-Michel Brunel
Rejuvenating the Activity of Usual Antibiotics on Resistant Gram-Negative Bacteria: Recent Issues and Perspectives. International journal of molecular sciences 24 (2) (2023)
René Dofini Magnini, François Pedinielli, Julia Vergalli, Noufou Ouedraogo, Simon Remy, Adama Hilou, Jean-Michel Brunel, Jean Marie Pagès, Anne Davin-Régli
Acacia senegal Budmunchiamines as a Potential Adjuvant for Rejuvenating Phenicol Activities towards Escherichia coli -Resistant Strains. International journal of molecular sciences 24 (10) (2023)
Melissa M Cadelis, Jisoo Kim, Florent Rouvier, Evangelene S Gill, Kyle Fraser, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
Exploration of Bis-Cinnamido-Polyamines as Intrinsic Antimicrobial Agents and Antibiotic Enhancers. Biomolecules 13 (7) (2023)
Melissa M Cadelis, Liam R Edmeades, Dan Chen, Evangelene S Gill, Kyle Fraser, Florent Rouvier, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
Investigation of Naphthyl-Polyamine Conjugates as Antimicrobials and Antibiotic Enhancers. Antibiotics (Basel, Switzerland) 12 (6) (2023)
Melissa M Cadelis, Tim Liu, Kenneth Sue, Florent Rouvier, Marie-Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
Structure-Activity Relationship Studies of Indolglyoxyl-Polyamine Conjugates as Antimicrobials and Antibiotic Potentiators. Pharmaceuticals (Basel, Switzerland) 16 (6) (2023)
Dan Chen, Daniel J Park, Melissa M Cadelis, Hana Douafer, Marie Lise Bourguet-Kondracki, Jean-Michel Brunel, Brent R Copp
Total Synthesis of the Four Stereoisomers of Cyclo(l-Trp-l-Arg) Raises Uncertainty of the Structures of the Natural Products and Invalidates Their Promising Antimicrobial Activities. Molecules (Basel, Switzerland) 27 (18) (2022)
Elmira F Khusnutdinova, Véronique Sinou, Denis A Babkov, Oxana B Kazakova, Jean-Michel Brunel
Development of New Antimicrobial Oleanonic Acid Polyamine Conjugates. Antibiotics (Basel, Switzerland) 11 (1) (2022)
Gang Wang, Jean-Michel Brunel, Matthias Preusse, Negar Mozaheb, Sven D Willger, Gerald Larrouy-Maumus, Pieter Baatsen, Susanne Häußler, Jean Michel Bolla, Françoise Van Bambeke
The membrane-active polyaminoisoprenyl compound NV716 re-sensitizes Pseudomonas aeruginosa to antibiotics and reduces bacterial virulence. Communications biology 5 (1) (2022)
Rodrigo Hernán Tomas-Grau, Florencia González-Lizárraga, Diego Ploper, César L Avila, Sergio B Socías, Pierre Besnault, Aurore Tourville, Rosa M Mella, Patricia Villacé, Clarisa Salado, Clémence Rose, Blandine Seon-Méniel, Jean-Michel Brunel, Laurent Ferrié, Rita Raisman-Vozari, Patrick Pierre Michel, Bruno Figadère, Rosana Chehín
Neuroprotective Effects of a Novel Demeclocycline Derivative Lacking Antibiotic Activity: From a Hit to a Promising Lead Compound. Cells 11 (17) (2022)
Emily S Smith-Peavler, Ronakkumar Patel, Adejumoke Mary Onumajuru, Bethany G Bowring, Joyce L Miller, Jean-Michel Brunel, Julianne Teresa Djordjevic, Moses M Prabu, Erin E McClelland
RTA1 Is Involved in Resistance to 7-Aminocholesterol and Secretion of Fungal Proteins in Cryptococcus neoformans . Pathogens (Basel, Switzerland) 11 (11) (2022)
Azza Troudi, Jean Michel Bolla, Naouel Klibi, Jean-Michel Brunel
An Original and Efficient Antibiotic Adjuvant Strategy to Enhance the Activity of Macrolide Antibiotics against Gram-Negative Resistant Strains. International journal of molecular sciences 23 (20) (2022)
Steven A Li, Rebecca J Zheng, Kenneth Sue, Marie-Lise Bourguet-Kondracki, Azza Troudi, Jean-Michel Brunel, Brent R Copp, Melissa M Cadelis
Discovery and Preliminary Structure-Activity Investigation of 3-Substituted-1 H -imidazol-5-yl-1 H -indoles with In Vitro Activity towards Methicillin-Resistant Staphylococcus aureus . Antibiotics (Basel, Switzerland) 11 (10) (2022)
Azza Troudi, Jean Marie Pagès, Jean-Michel Brunel
Chemical Highlights Supporting the Role of Lipid A in Efficient Biological Adaptation of Gram-Negative Bacteria to External Stresses. Journal of medicinal chemistry 64 (4) (2021)
Roberta Montanari, Davide Capelli, Keiko Yamamoto, Hirono Awaishima, Kimina Nishikata, Arjan Barendregt, Albert J R Heck, Fulvio Loiodice, Fabio Altieri, Alessandro Paiardini, Alessandro Grottesi, Luciano Pirone, Emilia Pedone, Franck Peiretti, Jean-Michel Brunel, Toshimasa Itoh, Giorgio Pochetti
Insights into PPARγ Phosphorylation and Its Inhibition Mechanism. Journal of medicinal chemistry 63 (9) (2020)
Aurélie Lieutaud, Cyril Pieri, Jean Michel Bolla, Jean-Michel Brunel
New Polyaminoisoprenyl Antibiotics Enhancers against Two Multidrug-Resistant Gram-Negative Bacteria from Enterobacter and Salmonella Species. Journal of medicinal chemistry 63 (18) (2020)
Dedieu Luc, Jean-Michel Brunel, Lorenzi Vanina, Muselli Alain, Berti Liliane, Jean Michel Bolla
Antibacterial Mode of Action of the Daucus carota Essential Oil Active Compounds against Campylobacter jejuni and Efflux-Mediated Drug Resistance in Gram-Negative Bacteria. Molecules (Basel, Switzerland) 25 (22) (2020)
Adrien Boes, Jean-Michel Brunel, Adeline Derouaux, Frédéric Kerff, Ahmed Bouhss, Thierry Touze, Eefjan Breukink, Mohammed Terrak
Squalamine and Aminosterol Mimics Inhibit the Peptidoglycan Glycosyltransferase Activity of PBP1b. Antibiotics (Basel, Switzerland) 9 (7) (2020)
Franck Peiretti, Roberta Montanari, Davide Capelli, Bernadette Bonardo, Cécilia Colson, Ez-Zoubir Amri, Marina Grimaldi, Patrick Balaguer, Keiichi Ito, Robert G Roeder, Giorgio Pochetti, Jean-Michel Brunel
A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor γ Binding Properties and Biological Activities. Journal of medicinal chemistry 63 (21) (2020)
Hana Douafer, Véronique Andrieu, Otto Phanstiel, Jean-Michel Brunel
Correction to Antibiotic Adjuvants: Make Antibiotics Great Again! Journal of medicinal chemistry 63 (3) (2020)
Azza Troudi, Meha Fethi, Mohamed Selim El Asli, Jean Michel Bolla, Naouel Klibi, Jean-Michel Brunel
Efficiency of a Tetracycline-Adjuvant Combination Against Multidrug Resistant Pseudomonas aeruginosa Tunisian Clinical Isolates. Antibiotics (Basel, Switzerland) 9 (12) (2020)
Hana Douafer, Véronique Andrieu, Otto Phanstiel, Jean-Michel Brunel
Antibiotic Adjuvants: Make Antibiotics Great Again! Journal of medicinal chemistry 62 (19) (2019)