Albert J R Heck (A J R Heck, Albert Jr Heck)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 178

Top Venues

Nature communications

Analytical chemistry

Journal of proteome research

Journal of the American Society for Mass Spectrometry

Universiteit Utrecht

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Universiteit Utrecht Sep 01 1998

Netherlands

Professor :: Pharmaceutical Sciences

Universiteit Utrecht Sep 01 1998

Netherlands

professor :: chemistry

Publications

Tereza Kadavá, Johannes F Hevler, Sofia Kalaidopoulou Nteak, Victor C Yin, Juergen Strasser, Johannes Preiner, Albert J R Heck
Higher-order structure and proteoforms of co-occurring C4b-binding protein assemblies in human serum. The EMBO journal 43 (14) (2024)
Victor C Yin, Evolène Deslignière, Nadia Mokiem, Inge Gazi, Rolf Lood, Carla J C de Haas, Suzan H M Rooijakkers, Albert J R Heck
Not All Arms of IgM Are Equal: Following Hinge-Directed Cleavage by Online Native SEC-Orbitrap-Based CDMS. Journal of the American Society for Mass Spectrometry 35 (6) (2024)
Victor C Yin, Evolène Deslignière, Nadia Mokiem, Inge Gazi, Rolf Lood, Carla J C de Haas, Suzan H M Rooijakkers, Albert J R Heck
Not All Arms of IgM Are Equal: Following Hinge-Directed Cleavage by Online Native SEC-Orbitrap-Based CDMS. Journal of the American Society for Mass Spectrometry 35 (6) (2024)
Sofia Kalaidopoulou Nteak, Franziska Völlmy, Marie V Lukassen, Henk W P van den Toorn, Maurits A den Boer, Albert Bondt, Sjors P A van der Lans, Pieter-Jan Haas, Arjan D van Zuilen, Suzan H M Rooijakkers, Albert J R Heck
Longitudinal Fluctuations in Protein Concentrations and Higher-Order Structures in the Plasma Proteome of Kidney Failure Patients Subjected to a Kidney Transplant. Journal of proteome research 23 (6) (2024)
Isabel Reinisch, Helene Michenthaler, Alba Sulaj, Elisabeth Moyschewitz, Jelena Krstic, Markus Galhuber, Ruonan Xu, Zina Riahi, Tongtong Wang, Nemanja Vujic, Melina Amor, Riccardo Zenezini Chiozzi, Martin Wabitsch, Dagmar Kolb, Anastasia Georgiadi, Lisa Glawitsch, Ellen Heitzer, Tim Julius Schulz, Michael Schupp, Wenfei Sun, Hua Dong, Adhideb Ghosh, Anne Hoffmann, Dagmar Kratky, Laura C Hinte, Ferdinand von Meyenn, Albert J R Heck, Matthias Blüher, Stephan Herzig, Christian Wolfrum, Andreas Prokesch
Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape. Nature communications 15 (1) (2024)
Inge Gazi, Karli R Reiding, André Groeneveld, Jan Bastiaans, Thom Huppertz, Albert J R Heck
LacdiNAc to LacNAc: remodelling of bovine α-lactalbumin N-glycosylation during the transition from colostrum to mature milk. Glycobiology 34 (9) (2024)
Evolène Deslignière, Victor C Yin, Eduard H T M Ebberink, Amber D Rolland, Arjan Barendregt, Tobias P Wörner, Konstantin O Nagornov, Anton N Kozhinov, Kyle L Fort, Yury O Tsybin, Alexander A Makarov, Albert J R Heck
Ultralong transients enhance sensitivity and resolution in Orbitrap-based single-ion mass spectrometry. Nature methods 21 (4) (2024)
Jan Fiala, Dina Schuster, Simon Ollivier, Stuart Pengelley, Markus Lubeck, Florian Busch, Andris Jankevics, Oliver Raether, Jean-Francois Greisch, Albert J R Heck
Protein-Centric Analysis of Personalized Antibody Repertoires Using LC-MS-Based Fab-Profiling on a timsTOF. Journal of the American Society for Mass Spectrometry 35 (6) (2024)
Evolène Deslignière, Victor C Yin, Eduard H T M Ebberink, Amber D Rolland, Arjan Barendregt, Tobias P Wörner, Konstantin O Nagornov, Anton N Kozhinov, Kyle L Fort, Yury O Tsybin, Alexander A Makarov, Albert J R Heck
Ultralong transients enhance sensitivity and resolution in Orbitrap-based single-ion mass spectrometry. Nature methods 21 (4) (2024)
Eva Maria Stork, Danique M H van Rijswijk, Karin Anna van Schie, Max Hoek, Theresa Kissel, Hans Ulrich Scherer, Thomas Wj Huizinga, Albert J R Heck, René E M Toes, Albert Bondt
Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis. Nature communications 15 (1) (2024)
Jan Fiala, Dina Schuster, Simon Ollivier, Stuart Pengelley, Markus Lubeck, Florian Busch, Andris Jankevics, Oliver Raether, Jean-Francois Greisch, Albert J R Heck
Protein-Centric Analysis of Personalized Antibody Repertoires Using LC-MS-Based Fab-Profiling on a timsTOF. Journal of the American Society for Mass Spectrometry 35 (6) (2024)
Tereza Kadavá, Johannes F Hevler, Sofia Kalaidopoulou Nteak, Victor C Yin, Juergen Strasser, Johannes Preiner, Albert J R Heck
Higher-order structure and proteoforms of co-occurring C4b-binding protein assemblies in human serum. The EMBO journal 43 (14) (2024)
Dipti Rai, Yinlong Song, Shasha Hua, Kelly Stecker, Jooske L Monster, Victor C Yin, Riccardo Stucchi, Yixin Xu, Yaqian Zhang, Fangrui Chen, Eugene A Katrukha, A F Maarten Altelaar, Albert J R Heck, Michal Wieczorek, Kai Jiang, Anna Akhmanova
CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRC. Nature cell biology (2024)
Jan Fiala, Dina Schuster, Simon Ollivier, Stuart Pengelley, Markus Lubeck, Florian Busch, Andris Jankevics, Oliver Raether, Jean-Francois Greisch, Albert J R Heck
Protein-Centric Analysis of Personalized Antibody Repertoires Using LC-MS-Based Fab-Profiling on a timsTOF. Journal of the American Society for Mass Spectrometry (2024)
Victor C Yin, Evolène Deslignière, Nadia Mokiem, Inge Gazi, Rolf Lood, Carla J C de Haas, Suzan H M Rooijakkers, Albert J R Heck
Not All Arms of IgM Are Equal: Following Hinge-Directed Cleavage by Online Native SEC-Orbitrap-Based CDMS. Journal of the American Society for Mass Spectrometry (2024)
Wouter van Bergen, Kristina Žuna, Jan Fiala, Elena E Pohl, Albert J R Heck, Marc P Baggelaar
Dual-Probe Activity-Based Protein Profiling Reveals Site-Specific Differences in Protein Binding of EGFR-Directed Drugs. ACS chemical biology 19 (8) (2024)
Sofia Kalaidopoulou Nteak, Franziska Völlmy, Marie V Lukassen, Henk W P van den Toorn, Maurits A den Boer, Albert Bondt, Sjors P A van der Lans, Pieter-Jan Haas, Arjan D van Zuilen, Suzan H M Rooijakkers, Albert J R Heck
Longitudinal Fluctuations in Protein Concentrations and Higher-Order Structures in the Plasma Proteome of Kidney Failure Patients Subjected to a Kidney Transplant. Journal of proteome research 23 (6) (2024)
Wouter van Bergen, Kristina Žuna, Jan Fiala, Elena E Pohl, Albert J R Heck, Marc P Baggelaar
Dual-Probe Activity-Based Protein Profiling Reveals Site-Specific Differences in Protein Binding of EGFR-Directed Drugs. ACS chemical biology (2024)
Isabel Reinisch, Helene Michenthaler, Alba Sulaj, Elisabeth Moyschewitz, Jelena Krstic, Markus Galhuber, Ruonan Xu, Zina Riahi, Tongtong Wang, Nemanja Vujic, Melina Amor, Riccardo Zenezini Chiozzi, Martin Wabitsch, Dagmar Kolb, Anastasia Georgiadi, Lisa Glawitsch, Ellen Heitzer, Tim Julius Schulz, Michael Schupp, Wenfei Sun, Hua Dong, Adhideb Ghosh, Anne Hoffmann, Dagmar Kratky, Laura C Hinte, Ferdinand von Meyenn, Albert J R Heck, Matthias Blüher, Stephan Herzig, Christian Wolfrum, Andreas Prokesch
Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape. Nature communications 15 (1) (2024)
Evolène Deslignière, Victor C Yin, Eduard H T M Ebberink, Amber D Rolland, Arjan Barendregt, Tobias P Wörner, Konstantin O Nagornov, Anton N Kozhinov, Kyle L Fort, Yury O Tsybin, Alexander A Makarov, Albert J R Heck
Ultralong transients enhance sensitivity and resolution in Orbitrap-based single-ion mass spectrometry. Nature methods 21 (4) (2024)
Inge Gazi, Karli R Reiding, André Groeneveld, Jan Bastiaans, Thom Huppertz, Albert J R Heck
LacdiNAc to LacNAc: remodelling of bovine α-lactalbumin N-glycosylation during the transition from colostrum to mature milk. Glycobiology 34 (9) (2024)
Eva Maria Stork, Danique M H van Rijswijk, Karin Anna van Schie, Max Hoek, Theresa Kissel, Hans Ulrich Scherer, Thomas Wj Huizinga, Albert J R Heck, René E M Toes, Albert Bondt
Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis. Nature communications 15 (1) (2024)
Dipti Rai, Yinlong Song, Shasha Hua, Kelly Stecker, Jooske L Monster, Victor C Yin, Riccardo Stucchi, Yixin Xu, Yaqian Zhang, Fangrui Chen, Eugene A Katrukha, A F Maarten Altelaar, Albert J R Heck, Michal Wieczorek, Kai Jiang, Anna Akhmanova
CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRC. Nature cell biology 26 (3) (2024)
Evolène Deslignière, Victor C Yin, Eduard H T M Ebberink, Amber D Rolland, Arjan Barendregt, Tobias P Wörner, Konstantin O Nagornov, Anton N Kozhinov, Kyle L Fort, Yury O Tsybin, Alexander A Makarov, Albert J R Heck
Ultralong transients enhance sensitivity and resolution in Orbitrap-based single-ion mass spectrometry. Nature methods (2024)
Victor C Yin, Evolène Deslignière, Nadia Mokiem, Inge Gazi, Rolf Lood, Carla J C de Haas, Suzan H M Rooijakkers, Albert J R Heck
Not All Arms of IgM Are Equal: Following Hinge-Directed Cleavage by Online Native SEC-Orbitrap-Based CDMS. Journal of the American Society for Mass Spectrometry 35 (6) (2024)
Tereza Kadavá, Johannes F Hevler, Sofia Kalaidopoulou Nteak, Victor C Yin, Juergen Strasser, Johannes Preiner, Albert J R Heck
Higher-order structure and proteoforms of co-occurring C4b-binding protein assemblies in human serum. The EMBO journal (2024)
Evolène Deslignière, Victor C Yin, Eduard H T M Ebberink, Amber D Rolland, Arjan Barendregt, Tobias P Wörner, Konstantin O Nagornov, Anton N Kozhinov, Kyle L Fort, Yury O Tsybin, Alexander A Makarov, Albert J R Heck
Ultralong transients enhance sensitivity and resolution in Orbitrap-based single-ion mass spectrometry. Nature methods 21 (4) (2024)
Wouter van Bergen, Kristina Žuna, Jan Fiala, Elena E Pohl, Albert J R Heck, Marc P Baggelaar
Dual-Probe Activity-Based Protein Profiling Reveals Site-Specific Differences in Protein Binding of EGFR-Directed Drugs. ACS chemical biology 19 (8) (2024)
Isabel Reinisch, Helene Michenthaler, Alba Sulaj, Elisabeth Moyschewitz, Jelena Krstic, Markus Galhuber, Ruonan Xu, Zina Riahi, Tongtong Wang, Nemanja Vujic, Melina Amor, Riccardo Zenezini Chiozzi, Martin Wabitsch, Dagmar Kolb, Anastasia Georgiadi, Lisa Glawitsch, Ellen Heitzer, Tim Julius Schulz, Michael Schupp, Wenfei Sun, Hua Dong, Adhideb Ghosh, Anne Hoffmann, Dagmar Kratky, Laura C Hinte, Ferdinand von Meyenn, Albert J R Heck, Matthias Blüher, Stephan Herzig, Christian Wolfrum, Andreas Prokesch
Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape. Nature communications 15 (1) (2024)
Inge Gazi, Karli R Reiding, André Groeneveld, Jan Bastiaans, Thom Huppertz, Albert J R Heck
LacdiNAc to LacNAc: remodelling of bovine α-lactalbumin N-glycosylation during the transition from colostrum to mature milk. Glycobiology 34 (9) (2024)
Dipti Rai, Yinlong Song, Shasha Hua, Kelly Stecker, Jooske L Monster, Victor C Yin, Riccardo Stucchi, Yixin Xu, Yaqian Zhang, Fangrui Chen, Eugene A Katrukha, A F Maarten Altelaar, Albert J R Heck, Michal Wieczorek, Kai Jiang, Anna Akhmanova
CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRC. Nature cell biology 26 (3) (2024)
Sofia Kalaidopoulou Nteak, Franziska Völlmy, Marie V Lukassen, Henk W P van den Toorn, Maurits A den Boer, Albert Bondt, Sjors P A van der Lans, Pieter-Jan Haas, Arjan D van Zuilen, Suzan H M Rooijakkers, Albert J R Heck
Longitudinal Fluctuations in Protein Concentrations and Higher-Order Structures in the Plasma Proteome of Kidney Failure Patients Subjected to a Kidney Transplant. Journal of proteome research (2024)
Isabel Reinisch, Helene Michenthaler, Alba Sulaj, Elisabeth Moyschewitz, Jelena Krstic, Markus Galhuber, Ruonan Xu, Zina Riahi, Tongtong Wang, Nemanja Vujic, Melina Amor, Riccardo Zenezini Chiozzi, Martin Wabitsch, Dagmar Kolb, Anastasia Georgiadi, Lisa Glawitsch, Ellen Heitzer, Tim Julius Schulz, Michael Schupp, Wenfei Sun, Hua Dong, Adhideb Ghosh, Anne Hoffmann, Dagmar Kratky, Laura C Hinte, Ferdinand von Meyenn, Albert J R Heck, Matthias Blüher, Stephan Herzig, Christian Wolfrum, Andreas Prokesch
Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape. Nature communications 15 (1) (2024)
Dipti Rai, Yinlong Song, Shasha Hua, Kelly Stecker, Jooske L Monster, Victor C Yin, Riccardo Stucchi, Yixin Xu, Yaqian Zhang, Fangrui Chen, Eugene A Katrukha, A F Maarten Altelaar, Albert J R Heck, Michal Wieczorek, Kai Jiang, Anna Akhmanova
CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRC. Nature cell biology 26 (3) (2024)
Eva Maria Stork, Danique M H van Rijswijk, Karin Anna van Schie, Max Hoek, Theresa Kissel, Hans Ulrich Scherer, Thomas Wj Huizinga, Albert J R Heck, René E M Toes, Albert Bondt
Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis. Nature communications 15 (1) (2024)
Wouter van Bergen, Kristina Žuna, Jan Fiala, Elena E Pohl, Albert J R Heck, Marc P Baggelaar
Dual-Probe Activity-Based Protein Profiling Reveals Site-Specific Differences in Protein Binding of EGFR-Directed Drugs. ACS chemical biology 19 (8) (2024)
Dipti Rai, Yinlong Song, Shasha Hua, Kelly Stecker, Jooske L Monster, Victor C Yin, Riccardo Stucchi, Yixin Xu, Yaqian Zhang, Fangrui Chen, Eugene A Katrukha, A F Maarten Altelaar, Albert J R Heck, Michal Wieczorek, Kai Jiang, Anna Akhmanova
CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRC. Nature cell biology 26 (3) (2024)
Eva Maria Stork, Danique M H van Rijswijk, Karin Anna van Schie, Max Hoek, Theresa Kissel, Hans Ulrich Scherer, Thomas Wj Huizinga, Albert J R Heck, René E M Toes, Albert Bondt
Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis. Nature communications 15 (1) (2024)
Tereza Kadavá, Johannes F Hevler, Sofia Kalaidopoulou Nteak, Victor C Yin, Juergen Strasser, Johannes Preiner, Albert J R Heck
Higher-order structure and proteoforms of co-occurring C4b-binding protein assemblies in human serum. The EMBO journal 43 (14) (2024)
Isabel Reinisch, Helene Michenthaler, Alba Sulaj, Elisabeth Moyschewitz, Jelena Krstic, Markus Galhuber, Ruonan Xu, Zina Riahi, Tongtong Wang, Nemanja Vujic, Melina Amor, Riccardo Zenezini Chiozzi, Martin Wabitsch, Dagmar Kolb, Anastasia Georgiadi, Lisa Glawitsch, Ellen Heitzer, Tim Julius Schulz, Michael Schupp, Wenfei Sun, Hua Dong, Adhideb Ghosh, Anne Hoffmann, Dagmar Kratky, Laura C Hinte, Ferdinand von Meyenn, Albert J R Heck, Matthias Blüher, Stephan Herzig, Christian Wolfrum, Andreas Prokesch
Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape. Nature communications 15 (1) (2024)
Tereza Kadavá, Johannes F Hevler, Sofia Kalaidopoulou Nteak, Victor C Yin, Juergen Strasser, Johannes Preiner, Albert J R Heck
Higher-order structure and proteoforms of co-occurring C4b-binding protein assemblies in human serum. The EMBO journal 43 (14) (2024)
Eva Maria Stork, Danique M H van Rijswijk, Karin Anna van Schie, Max Hoek, Theresa Kissel, Hans Ulrich Scherer, Thomas Wj Huizinga, Albert J R Heck, René E M Toes, Albert Bondt
Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis. Nature communications 15 (1) (2024)
Dipti Rai, Yinlong Song, Shasha Hua, Kelly Stecker, Jooske L Monster, Victor C Yin, Riccardo Stucchi, Yixin Xu, Yaqian Zhang, Fangrui Chen, Eugene A Katrukha, A F Maarten Altelaar, Albert J R Heck, Michal Wieczorek, Kai Jiang, Anna Akhmanova
CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRC. Nature cell biology 26 (3) (2024)
Sofia Kalaidopoulou Nteak, Franziska Völlmy, Marie V Lukassen, Henk W P van den Toorn, Maurits A den Boer, Albert Bondt, Sjors P A van der Lans, Pieter-Jan Haas, Arjan D van Zuilen, Suzan H M Rooijakkers, Albert J R Heck
Longitudinal Fluctuations in Protein Concentrations and Higher-Order Structures in the Plasma Proteome of Kidney Failure Patients Subjected to a Kidney Transplant. Journal of proteome research 23 (6) (2024)
Jan Fiala, Dina Schuster, Simon Ollivier, Stuart Pengelley, Markus Lubeck, Florian Busch, Andris Jankevics, Oliver Raether, Jean-Francois Greisch, Albert J R Heck
Protein-Centric Analysis of Personalized Antibody Repertoires Using LC-MS-Based Fab-Profiling on a timsTOF. Journal of the American Society for Mass Spectrometry 35 (6) (2024)
Danique M H van Rijswijck, Albert Bondt, Naomi de Kat, Rolf Lood, Albert J R Heck
Direct Comparison of the Hinge-Cleaving Proteases IgdE and BdpK for LC-MS-Based IgG1 Clonal Profiling. Analytical chemistry 96 (1) (2023)
Johannes F Hevler, Pascal Albanese, Alfredo Cabrera-Orefice, Alisa Potter, Andris Jankevics, Jelena Misic, Richard A Scheltema, Ulrich Brandt, Susanne Arnold, Albert J R Heck
MRPS36 provides a structural link in the eukaryotic 2-oxoglutarate dehydrogenase complex. Open biology 13 (3) (2023)
Leire Aguinagalde, Maurits A den Boer, Suzanne M Castenmiller, Seline A Zwarthoff, Carla de Haas, Piet C Aerts, Frank J Beurskens, Janine Schuurman, Albert J R Heck, Kok van Kessel, Suzan H M Rooijakkers
Promoting Fc-Fc interactions between anti-capsular antibodies provides strong immune protection against Streptococcus pneumoniae . eLife 12 (2023)
Alena Khmelinskaia, Neville P Bethel, Farzad Fatehi, Aleksandar Antanasijevic, Andrew J Borst, Szu-Hsueh Lai, Jing Yang John Wang, Bhoomika Basu Mallik, Marcos C Miranda, Andrew M Watkins, Cassandra Ogohara, Shane Caldwell, Mengyu Wu, Albert J R Heck, David Veesler, Andrew B Ward, David Baker, Reidun Twarock, Neil P King
Local structural flexibility drives oligomorphism in computationally designed protein assemblies. bioRxiv : the preprint server for biology (2023)
Danique M H van Rijswijck, Albert Bondt, Naomi de Kat, Rolf Lood, Albert J R Heck
Direct Comparison of the Hinge-Cleaving Proteases IgdE and BdpK for LC-MS-Based IgG1 Clonal Profiling. Analytical chemistry 96 (1) (2023)
Johannes F Hevler, Pascal Albanese, Alfredo Cabrera-Orefice, Alisa Potter, Andris Jankevics, Jelena Misic, Richard A Scheltema, Ulrich Brandt, Susanne Arnold, Albert J R Heck
MRPS36 provides a structural link in the eukaryotic 2-oxoglutarate dehydrogenase complex. Open biology 13 (3) (2023)
Danique M H van Rijswijck, Albert Bondt, Naomi de Kat, Rolf Lood, Albert J R Heck
Direct Comparison of the Hinge-Cleaving Proteases IgdE and BdpK for LC-MS-Based IgG1 Clonal Profiling. Analytical chemistry 96 (1) (2023)
Weiwei Peng, Maurits A den Boer, Sem Tamara, Nadia J Mokiem, Sjors P A van der Lans, Albert Bondt, Douwe Schulte, Pieter-Jan Haas, Monique C Minnema, Suzan H M Rooijakkers, Arjan D van Zuilen, Albert J R Heck, Joost Snijder
Direct Mass Spectrometry-Based Detection and Antibody Sequencing of Monoclonal Gammopathy of Undetermined Significance from Patient Serum: A Case Study. Journal of proteome research (2023)
Nienke Oskam, Maurits A den Boer, Marie V Lukassen, Pleuni Ooijevaar-de Heer, Tim S Veth, Gerard van Mierlo, Szu-Hsueh Lai, Ninotska I L Derksen, Victor C Yin, Marij Streutker, Vojtech Franc, Marta Šiborová, Mirjam J A Damen, Dorien Kos, Arjan Barendregt, Albert Bondt, Johannes Hans B van Goudoever, Carla J C de Haas, Piet C Aerts, Remy M Muts, Suzan H M Rooijakkers, Gestur Vidarsson, Theo Rispens, Albert J R Heck
CD5L is a canonical component of circulatory IgM. Proceedings of the National Academy of Sciences of the United States of America 120 (50) (2023)
Gunasekaran Subramaniam, Katharina Schleicher, Duangnapa Kovanich, Anna Zerio, Milda Folkmanaite, Ying-Chi Chao, Nicoletta C Surdo, Andreas Koschinski, Jianshu Hu, Arjen Scholten, Albert J R Heck, Maria Ercu, Anastasiia Sholokh, Kyung Chan Park, Anastasiia Sholokh, Viviana Meraviglia, Milena Bellin, Sara Zanivan, Svenja Hester, Shabaz Mohammed, Manuela Zaccolo
Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy. Circulation research (2023)
Johannes F Hevler, Pascal Albanese, Alfredo Cabrera-Orefice, Alisa Potter, Andris Jankevics, Jelena Misic, Richard A Scheltema, Ulrich Brandt, Susanne Arnold, Albert J R Heck
MRPS36 provides a structural link in the eukaryotic 2-oxoglutarate dehydrogenase complex. Open biology 13 (3) (2023)
Gunasekaran Subramaniam, Katharina Schleicher, Duangnapa Kovanich, Anna Zerio, Milda Folkmanaite, Ying-Chi Chao, Nicoletta C Surdo, Andreas Koschinski, Jianshu Hu, Arjen Scholten, Albert J R Heck, Maria Ercu, Anastasiia Sholokh, Kyung Chan Park, Anastasiia Sholokh, Viviana Meraviglia, Milena Bellin, Sara Zanivan, Svenja Hester, Shabaz Mohammed, Manuela Zaccolo
Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy. Circulation research (2023)
Danique M H van Rijswijck, Albert Bondt, Naomi de Kat, Rolf Lood, Albert J R Heck
Direct Comparison of the Hinge-Cleaving Proteases IgdE and BdpK for LC-MS-Based IgG1 Clonal Profiling. Analytical chemistry 96 (1) (2023)
Shelley Jager, Dario A T Cramer, Albert J R Heck
Normal Alpha-1-Antitrypsin Variants Display in Serum Allele-Specific Protein Levels. Journal of proteome research (2023)
Leire Aguinagalde, Maurits A den Boer, Suzanne M Castenmiller, Seline A Zwarthoff, Carla de Haas, Piet C Aerts, Frank J Beurskens, Janine Schuurman, Albert J R Heck, Kok van Kessel, Suzan H M Rooijakkers
Promoting Fc-Fc interactions between anti-capsular antibodies provides strong immune protection against Streptococcus pneumoniae . eLife 12 (2023)
Johannes F Hevler, Pascal Albanese, Alfredo Cabrera-Orefice, Alisa Potter, Andris Jankevics, Jelena Misic, Richard A Scheltema, Ulrich Brandt, Susanne Arnold, Albert J R Heck
MRPS36 provides a structural link in the eukaryotic 2-oxoglutarate dehydrogenase complex. Open biology 13 (3) (2023)
Gunasekaran Subramaniam, Katharina Schleicher, Duangnapa Kovanich, Anna Zerio, Milda Folkmanaite, Ying-Chi Chao, Nicoletta C Surdo, Andreas Koschinski, Jianshu Hu, Arjen Scholten, Albert J R Heck, Maria Ercu, Anastasiia Sholokh, Kyung Chan Park, Anastasiia Sholokh, Viviana Meraviglia, Milena Bellin, Sara Zanivan, Svenja Hester, Shabaz Mohammed, Manuela Zaccolo
Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy. Circulation research (2023)
Juan Manuel Valverde, Geronimo Dubra, Michael Phillips, Austin Haider, Carlos Elena-Real, Aurélie Fournet, Emile Alghoul, Dhanvantri Chahar, Nuria Andrés-Sanchez, Matteo Paloni, Pau Bernadó, Guido van Mierlo, Michiel Vermeulen, Henk W P van den Toorn, Albert J R Heck, Angelos Constantinou, Alessandro Barducci, Kingshuk Ghosh, Nathalie Sibille, Puck Knipscheer, Liliana Krasinska, Daniel Fisher, A F Maarten Altelaar
A cyclin-dependent kinase-mediated phosphorylation switch of disordered protein condensation. Nature communications 14 (1) (2023)
Danique M H van Rijswijck, Albert Bondt, Naomi de Kat, Rolf Lood, Albert J R Heck
Direct Comparison of the Hinge-Cleaving Proteases IgdE and BdpK for LC-MS-Based IgG1 Clonal Profiling. Analytical chemistry 96 (1) (2023)
Johannes F Hevler, Pascal Albanese, Alfredo Cabrera-Orefice, Alisa Potter, Andris Jankevics, Jelena Misic, Richard A Scheltema, Ulrich Brandt, Susanne Arnold, Albert J R Heck
MRPS36 provides a structural link in the eukaryotic 2-oxoglutarate dehydrogenase complex. Open biology 13 (3) (2023)
Danique M H van Rijswijck, Albert Bondt, Naomi de Kat, Rolf Lood, Albert J R Heck
Direct Comparison of the Hinge-Cleaving Proteases IgdE and BdpK for LC-MS-Based IgG1 Clonal Profiling. Analytical chemistry (2023)
Leire Aguinagalde, Maurits A den Boer, Suzanne M Castenmiller, Seline A Zwarthoff, Carla de Haas, Piet C Aerts, Frank J Beurskens, Janine Schuurman, Albert J R Heck, Kok van Kessel, Suzan H M Rooijakkers
Promoting Fc-Fc interactions between anti-capsular antibodies provides strong immune protection against Streptococcus pneumoniae . eLife 12 (2023)
Victor C Yin, Paul W A Devine, Janet C Saunders, Arjan Barendregt, Fiona Cusdin, Alexandra Ristani, Alistair Hines, Sam Shepherd, Marcin Dembek, Claire L Dobson, Joost Snijder, Nicholas J Bond, Albert J R Heck
Stochastic assembly of biomacromolecular complexes: impact and implications on charge interpretation in native mass spectrometry. Chemical science 14 (35) (2023)
Evolène Deslignière, Amber Rolland, Eduard H T M Ebberink, Victor C Yin, Albert J R Heck
Orbitrap-Based Mass and Charge Analysis of Single Molecules. Accounts of chemical research (2023)
Niels M Leijten, Albert J R Heck, Simone Lemeer
Histidine phosphorylation in human cells; a needle or phantom in the haystack? Nature methods 19 (7) (2022)
Kelly A Dingess, Max Hoek, Danique M H van Rijswijk, Sem Tamara, Maurits A den Boer, Tim Veth, Mirjam J A Damen, Arjan Barendregt, Michelle Romijn, Hannah G Juncker, Britt J van Keulen, Gestur Vidarsson, Johannes B van Goudoever, Albert Bondt, Albert J R Heck
Identification of common and distinct origins of human serum and breastmilk IgA1 by mass spectrometry-based clonal profiling. Cellular & molecular immunology (2022)
Lucas M P Chataigner, Christos Gogou, Maurits A den Boer, Cátia P Frias, Dominique M E Thies-Weesie, Joke C M Granneman, Albert J R Heck, Dimphna H Meijer, Bert J C Janssen
Structural insights into the contactin 1 - neurofascin 155 adhesion complex. Nature communications 13 (1) (2022)
Jelena Krstic, Isabel Reinisch, Katharina Schindlmaier, Markus Galhuber, Zina Riahi, Natascha Berger, Nadja Kupper, Elisabeth Moyschewitz, Martina Auer, Helene Michenthaler, Christoph Nössing, Maria R Depaoli, Jeta Ramadani-Muja, Sinem Usluer, Sarah Stryeck, Martin Pichler, Beate Rinner, Alexander J A Deutsch, Andreas Reinisch, Tobias Madl, Riccardo Zenezini Chiozzi, Albert J R Heck, Meritxell Huch, Roland Malli, Andreas Prokesch
Fasting improves therapeutic response in hepatocellular carcinoma through p53-dependent metabolic synergism. Science advances 8 (3) (2022)
Ivan Corbeski, Xiaohu Guo, Bruna V Eckhardt, Domenico Fasci, Wouter Wiegant, Melissa A Graewert, Kees Vreeken, Hans Wienk, Dmitri I Svergun, Albert J R Heck, Haico van Attikum, Rolf Boelens, Titia K Sixma, Francesca Mattiroli, Hugo van Ingen
Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF. Science advances 8 (30) (2022)
Dennis J Doorduijn, Marie V Lukassen, Marije F L van 't Wout, Vojtech Franc, Maartje Ruyken, Bart W Bardoel, Albert J R Heck, Suzan H M Rooijakkers
Soluble MAC is primarily released from MAC-resistant bacteria that potently convert complement component C5. eLife 11 (2022)
Pim R R van Gorp, Juan Zhang, Jia Liu, Roula Tsonaka, Hailiang Mei, Sven O Dekker, Cindy I Bart, Tim De Coster, Harm Post, Albert J R Heck, Martin J Schalij, Douwe E Atsma, Daniel A Pijnappels, Antoine A F de Vries
Sbk2, a Newly Discovered Atrium-Enriched Regulator of Sarcomere Integrity. Circulation research 131 (1) (2022)
Danique M H van Rijswijk, Albert Bondt, Max Hoek, Karlijn van der Straten, Tom G Caniels, Meliawati Poniman, Dirk Eggink, Chantal B E M Reusken, Godelieve J de Bree, Rogier W Sanders, Marit J VAN Gils, Albert J R Heck
Discriminating cross-reactivity in polyclonal IgG1 responses against SARS-CoV-2 variants of concern. Nature communications 13 (1) (2022)
Dario A T Cramer, Vojtech Franc, Tomislav Caval, Albert J R Heck
Charting the Proteoform Landscape of Serum Proteins in Individual Donors by High-Resolution Native Mass Spectrometry. Analytical chemistry 94 (37) (2022)
Tobias P Wörner, Konstantin Aizikov, Joost Snijder, Kyle L Fort, Alexander A Makarov, Albert J R Heck
Frequency chasing of individual megadalton ions in an Orbitrap analyser improves precision of analysis in single-molecule mass spectrometry. Nature chemistry 14 (5) (2022)
Elyse S Fischer, Conny W H Yu, Johannes F Hevler, Stephen H McLaughlin, Sarah L Maslen, Albert J R Heck, Stefan M V Freund, David Barford
Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly. Nature communications 13 (1) (2022)
Sebastiaan C de Graaf, Max Hoek, Sem Tamara, Albert J R Heck
A perspective toward mass spectrometry-based de novo sequencing of endogenous antibodies. mAbs 14 (1) (2022)
Sem Tamara, Maurits A den Boer, Albert J R Heck
High-Resolution Native Mass Spectrometry. Chemical reviews (2021)
Guusje van Schaick, Elena Domínguez-Vega, Christoph Gstöttner, Johanna H van den Berg-Verleg, Olaf Schouten, Michiel Akeroyd, Maurien M A Olsthoorn, Dana L E Vergoossen, Albert J R Heck, Nicolas Abello, Vojtech Franc
Native Structural and Functional Proteoform Characterization of the Prolyl-Alanyl-Specific Endoprotease EndoPro from Aspergillus niger. Journal of proteome research 20 (10) (2021)
Jean-Francois Greisch, Maurits A den Boer, Frank Beurskens, Janine Schuurman, Sem Tamara, Albert Bondt, Albert J R Heck
Generating Informative Sequence Tags from Antigen-Binding Regions of Heavily Glycosylated IgA1 Antibodies by Native Top-Down Electron Capture Dissociation. Journal of the American Society for Mass Spectrometry 32 (6) (2021)
Johannes F Hevler, Marie V Lukassen, Alfredo Cabrera-Orefice, Susanne Arnold, Matti Feije Pronker, Vojtech Franc, Albert J R Heck
Selective cross-linking of coinciding protein assemblies by in-gel cross-linking mass spectrometry. The EMBO journal 40 (4) (2021)
Victor C Yin, Szu-Hsueh Lai, Tom G Caniels, Philip J M Brouwer, Mitch Brinkkemper, Yoann Aldon, Hejun Liu, Meng Yuan, Ian A Wilson, Rogier W Sanders, Marit J van Gils, Albert J R Heck
Probing Affinity, Avidity, Anticooperativity, and Competition in Antibody and Receptor Binding to the SARS-CoV-2 Spike by Single Particle Mass Analyses. ACS central science 7 (11) (2021)
Franziska Völlmy, Henk van den Toorn, Riccardo Zenezini Chiozzi, Ottavio Zucchetti, Alberto Papi, Carlo Alberto Volta, Luisa Marracino, Francesco Vieceli Dalla Sega, Francesca Fortini, Vadim Demichev, Pinkus Tober-Lau, Gianluca Campo, Marco Contoli, Markus Ralser, Florian Kurth, Spadaro Savino, Paola Rizzo, Albert J R Heck
A serum proteome signature to predict mortality in severe COVID-19 patients. Life science alliance 4 (9) (2021)
Britt J Van Keulen, Michelle Romijn, Albert Bondt, Kelly A Dingess, Eva Kontopodi, Karlijn van der Straten, Maurits A den Boer, Judith A Burger, Meliawati Poniman, Berend J Bosch, Philip J M Brouwer, Christianne J M de Groot, Max Hoek, Wentao Li, Dasja Pajkrt, Rogier W Sanders, Anne Schoonderwoerd, Sem Tamara, Rian A H Timmermans, Gestur Vidarsson, Koert J Stittelaar, Theo T Rispens, Kasper Arthur Hettinga, Marit J van Gils, Albert J R Heck, Johannes Hans B van Goudoever
Human Milk from Previously COVID-19-Infected Mothers: The Effect of Pasteurization on Specific Antibodies and Neutralization Capacity. Nutrients 13 (5) (2021)
Miguel Ricardo Leung, Riccardo Zenezini Chiozzi, Marc C Roelofs, Johannes F Hevler, Ravi Teja Ravi, Paula P Maitan, Min Zhang, Heiko Henning, Elizabeth G Bromfield, Stuart C Howes, Bart M Gadella, Albert J R Heck, Tzviya Zeev-Ben-Mordehai
In-cell structures of conserved supramolecular protein arrays at the mitochondria-cytoskeleton interface in mammalian sperm. Proceedings of the National Academy of Sciences of the United States of America 118 (45) (2021)
Karli R Reiding, Yu-Hsien Lin, Floris P J van Alphen, Alexander B Meijer, Albert J R Heck
Neutrophil azurophilic granule glycoproteins are distinctively decorated by atypical pauci- and phosphomannose glycans. Communications biology 4 (1) (2021)
Dominik Brücher, Vojtech Franc, Sheena N Smith, Albert J R Heck, Andreas Plückthun
Malignant tissues produce divergent antibody glycosylation of relevance for cancer gene therapy effectiveness. mAbs 12 (1) (2021)
Anjusha Mathew, Ronald Buijs, Gert B Eijkel, Frans Giskes, Andrey Dyachenko, Jerre van der Horst, Dimitry Byelov, Dirk-Jan Spaanderman, Albert J R Heck, Tiffany Porta Siegel, Shane R Ellis, Ron M A Heeren
Ion Imaging of Native Protein Complexes Using Orthogonal Time-of-Flight Mass Spectrometry and a Timepix Detector. Journal of the American Society for Mass Spectrometry 32 (2) (2021)
Adam J Wargacki, Tobias P Wörner, Michiel van de Waterbeemd, Daniel Ellis, Albert J R Heck, Neil P King
Complete and cooperative in vitro assembly of computationally designed self-assembling protein nanomaterials. Nature communications 12 (1) (2021)
Tobias P Wörner, Antonette Bennett, Sana Habka, Joost Snijder, Olga Friese, Thomas Powers, Mavis Agbandje-McKenna, Albert J R Heck
Adeno-associated virus capsid assembly is divergent and stochastic. Nature communications 12 (1) (2021)
Julia Bauzá-Martinez, Albert J R Heck, Wei Wu
HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles. Communications biology 4 (1) (2021)
Jean-Francois Greisch, Maurits A den Boer, Szu-Hsueh Lai, Kelly Gallagher, Albert Bondt, Jan Commandeur, Albert J R Heck
Extending Native Top-Down Electron Capture Dissociation to MDa Immunoglobulin Complexes Provides Useful Sequence Tags Covering Their Critical Variable Complementarity-Determining Regions. Analytical chemistry 93 (48) (2021)
Maurits A den Boer, Szu-Hsueh Lai, Xiaoguang Xue, Muriel D van Kampen, Boris Bleijlevens, Albert J R Heck
Comparative Analysis of Antibodies and Heavily Glycosylated Macromolecular Immune Complexes by Size-Exclusion Chromatography Multi-Angle Light Scattering, Native Charge Detection Mass Spectrometry, and Mass Photometry. Analytical chemistry 94 (2) (2021)
Anna Mari Lone, Piero Giansanti, Marthe Jøntvedt Jørgensen, Enio Gjerga, Aurélien J F Dugourd, Arjen Scholten, Julio Saez-Rodriguez, Albert J R Heck, Kjetil Taskén
Systems approach reveals distinct and shared signaling networks of the four PGE2 receptors in T cells. Science signaling 14 (703) (2021)
Johannes F Hevler, Riccardo Zenezini Chiozzi, Alfredo Cabrera-Orefice, Ulrich Brandt, Susanne Arnold, Albert J R Heck
Molecular characterization of a complex of apoptosis-inducing factor 1 with cytochrome c oxidase of the mitochondrial respiratory chain. Proceedings of the National Academy of Sciences of the United States of America 118 (39) (2021)
Ana Rita Cruz, Maurits A den Boer, Juergen Strasser, Seline A Zwarthoff, Frank J Beurskens, Carla J C de Haas, Piet C Aerts, Guanbo Wang, Rob N de Jong, Fabio Bagnoli, Jos A G van Strijp, Kok P M van Kessel, Janine Schuurman, Johannes Preiner, Albert J R Heck, Suzan H M Rooijakkers
Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation. Proceedings of the National Academy of Sciences of the United States of America 118 (7) (2021)

Albert J R Heck.css-eqlu8i{font-size:small;padding-left:4px;} (A J R Heck, Albert Jr Heck)

Publication Activity (10 Years)

Top Topics

Top Venues

Albert J R Heck (A J R Heck, Albert Jr Heck)