James A Thomas (Jim A Thomas)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 36

Top Topics

Energy Transfer

Staphylococcus Aureus

Top Venues

Journal of the American Chemical Society

Chemical science

Dalton transactions (Cambridge, England : 2003)

Chemistry (Weinheim an der Bergstrasse, Germany)

This page only lists publications with an associated author ORCID identifier.

Publications

Felicity F Noakes, Kirsty L Smitten, Laura E C Maple, Jorge Bernardino de La Serna, Craig C Robertson, Dylan Pritchard, Simon D Fairbanks, Julia A Weinstein, Carl G W Smythe, James A Thomas
Phenazine Cations as Anticancer Theranostics † . Journal of the American Chemical Society 146 (18) (2024)
Felicity F Noakes, Kirsty L Smitten, Laura E C Maple, Jorge Bernardino de La Serna, Craig C Robertson, Dylan Pritchard, Simon D Fairbanks, Julia A Weinstein, Carl G W Smythe, James A Thomas
Phenazine Cations as Anticancer Theranostics † . Journal of the American Chemical Society 146 (18) (2024)
Felicity F Noakes, Kirsty L Smitten, Laura E C Maple, Jorge Bernardino de La Serna, Craig C Robertson, Dylan Pritchard, Simon D Fairbanks, Julia A Weinstein, Carl G W Smythe, James A Thomas
Phenazine Cations as Anticancer Theranostics † . Journal of the American Chemical Society 146 (18) (2024)
Felicity F Noakes, Kirsty L Smitten, Laura E C Maple, Jorge Bernardino de La Serna, Craig C Robertson, Dylan Pritchard, Simon D Fairbanks, Julia A Weinstein, Carl G W Smythe, James A Thomas
Phenazine Cations as Anticancer Theranostics † . Journal of the American Chemical Society (2024)
Stephen O Aderinto, Torsten John, Abdulmujeeb Onawole, Raphael Peter Galleh, James A Thomas
Iridium(III)-based minor groove binding complexes as DNA photocleavage agents. Dalton transactions (Cambridge, England : 2003) 53 (17) (2024)
Stephen O Aderinto, Torsten John, Abdulmujeeb Onawole, Raphael Peter Galleh, James A Thomas
Iridium(III)-based minor groove binding complexes as DNA photocleavage agents. Dalton transactions (Cambridge, England : 2003) 53 (17) (2024)
Stephen O Aderinto, Torsten John, Abdulmujeeb Onawole, Raphael Peter Galleh, James A Thomas
Iridium(III)-based minor groove binding complexes as DNA photocleavage agents. Dalton transactions (Cambridge, England : 2003) (2024)
Adam M Varney, Kirsty L Smitten, Hannah M Southam, Simon D Fairbanks, Craig C Robertson, James A Thomas, Samantha McLean
In Vitro and In Vivo Studies on a Mononuclear Ruthenium Complex Reveals It is a Highly Effective, Fast-Acting, Broad-Spectrum Antimicrobial in Physiologically Relevant Conditions. ACS infectious diseases (2024)
Stephen O Aderinto, James A Thomas, Craig C Robertson
2,2':4,4'':4',4'''-Quaterpyridine: synthesis, crystal-structure description, and Hirshfeld surface analysis. Acta crystallographica. Section E, Crystallographic communications 79 (Pt 4) (2023)
Nur Aininie Yusoh, Paul R Tiley, Steffan D James, Siti Norain Harun, James A Thomas, Norazalina Saad, Ling-Wei Hii, Suet Lin Chia, Martin R Gill, Haslina Ahmad
Discovery of Ruthenium(II) Metallocompound and Olaparib Synergy for Cancer Combination Therapy. Journal of medicinal chemistry (2023)
Martin R Gill, Paul J Jarman, Vanessa Hearnden, Simon D Fairbanks, Marcella Bassetto, Hannes Maib, John Palmer, Kathryn R Ayscough, James A Thomas, Carl Smythe
A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 134 (27) (2022)
Ahtasham Raza, Stuart A Archer, James A Thomas, Sheila MacNeil, John W Haycock
Selectively inhibiting malignant melanoma migration and invasion in an engineered skin model using actin-targeting dinuclear Ru II -complexes. RSC medicinal chemistry 14 (1) (2022)
Sumit Kumar Pramanik, Sreejesh Sreedharan, Rajeshwari Tiwari, Sourav Dutta, Noufal Kandoth, Surajit Barman, Stephen O Aderinto, Samit Chattopadhyay, Amitava Das, James A Thomas
Nanoparticles for super-resolution microscopy: intracellular delivery and molecular targeting. Chemical Society reviews (2022)
Martin R Gill, Paul J Jarman, Vanessa Hearnden, Simon D Fairbanks, Marcella Bassetto, Hannes Maib, John Palmer, Kathryn R Ayscough, James A Thomas, Carl Smythe
A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 134 (27) (2022)
Ahtasham Raza, Stuart A Archer, James A Thomas, Sheila MacNeil, John W Haycock
Selectively inhibiting malignant melanoma migration and invasion in an engineered skin model using actin-targeting dinuclear Ru II -complexes. RSC medicinal chemistry 14 (1) (2022)
Martin R Gill, Paul J Jarman, Vanessa Hearnden, Simon D Fairbanks, Marcella Bassetto, Hannes Maib, John Palmer, Kathryn R Ayscough, James A Thomas, Carl Smythe
A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis. Angewandte Chemie (International ed. in English) 61 (27) (2022)
Fabian Dröge, Felicity F Noakes, Stuart A Archer, Sreejesh Sreedharan, Ahtasham Raza, Craig C Robertson, Sheila MacNeil, John W Haycock, Heather Carson, Anthony J H M Meijer, Carl G W Smythe, Jorge Bernardino de La Serna, Benjamin Dietzek-Ivanšić, James A Thomas
A Dinuclear Osmium(II) Complex Near-Infrared Nanoscopy Probe for Nuclear DNA. Journal of the American Chemical Society 143 (48) (2021)
James D Grayson, Matthew P Baumgartner, Cleide Dos Santos Souza, Samuel J Dawes, Imane Ghafir El Idrissi, Jennifer C Louth, Sasha Stimpson, Emma Mead, Charlotte Dunbar, Joanna Wolak, Gary Sharman, David A Evans, Anastasia Zhuravleva, Margarita Segovia Roldan, Nicola Antonio Colabufo, Ke Ning, Claire Garwood, James A Thomas, Benjamin M Partridge, Antonio de la Vega de León, Valerie J Gillet, Amélia Pilar Rauter, Beining Chen
Amyloid binding and beyond: a new approach for Alzheimer's disease drug discovery targeting Aβo-PrPC binding and downstream pathways. Chemical science 12 (10) (2021)
Hiwa K Saeed, Sreejesh Sreedharan, James A Thomas
Photoactive metal complexes that bind DNA and other biomolecules as cell probes, therapeutics, and theranostics. Chemical communications (Cambridge, England) 56 (10) (2020)
Kirsty L Smitten, Paul A Scattergood, Charlotte Kiker, James A Thomas, Paul I P Elliott
Triazole-based osmium(ii) complexes displaying red/near-IR luminescence: antimicrobial activity and super-resolution imaging. Chemical science 11 (33) (2020)
Martin R Gill, Michael G Walker, Sarah Able, Ole Tietz, Abirami Lakshminarayanan, Rachel Anderson, Rod Chalk, Afaf H El-Sagheer, Tom Brown, James A Thomas, Katherine A Vallis
An 111In-labelled bis-ruthenium(ii) dipyridophenazine theranostic complex: mismatch DNA binding and selective radiotoxicity towards MMR-deficient cancer cells. Chemical science 11 (33) (2020)
Ahtasham Raza, Stuart A Archer, Simon D Fairbanks, Kirsty L Smitten, Stanley W Botchway, James A Thomas, Sheila MacNeil, John W Haycock
A Dinuclear Ruthenium(II) Complex Excited by Near-Infrared Light through Two-Photon Absorption Induces Phototoxicity Deep within Hypoxic Regions of Melanoma Cancer Spheroids. Journal of the American Chemical Society 142 (10) (2020)
Hiwa K Saeed, Sreejesh Sreedharan, Paul J Jarman, Stuart A Archer, Simon D Fairbanks, Simon P Foxon, Alexander J Auty, Dimitri Chekulaev, Theo Keane, Anthony J H M Meijer, Julia A Weinstein, Carl G W Smythe, Jorge Bernardino de La Serna, James A Thomas
Making the Right Link to Theranostics: The Photophysical and Biological Properties of Dinuclear RuII-ReI dppz Complexes Depend on Their Tether. Journal of the American Chemical Society 142 (2) (2019)
Simon D Fairbanks, Craig C Robertson, F Richard Keene, James A Thomas, Michael P Williamson
Structural Investigation into the Threading Intercalation of a Chiral Dinuclear Ruthenium(II) Polypyridyl Complex through a B-DNA Oligonucleotide. Journal of the American Chemical Society 141 (11) (2019)
Stuart A Archer, Ahtasham Raza, Fabian Dröge, Craig Robertson, Alexander J Auty, Dimitri Chekulaev, Julia A Weinstein, Theo Keane, Anthony J H M Meijer, John W Haycock, Sheila MacNeil, James A Thomas
A dinuclear ruthenium(ii) phototherapeutic that targets duplex and quadruplex DNA. Chemical science 10 (12) (2019)
Paul J Jarman, Felicity Noakes, Simon Fairbanks, Kirsty Smitten, Isabel K Griffiths, Hiwa K Saeed, James A Thomas, Carl G W Smythe
Exploring the Cytotoxicity, Uptake, Cellular Response, and Proteomics of Mono- and Dinuclear DNA Light-Switch Complexes. Journal of the American Chemical Society 141 (7) (2019)
Kirsty L Smitten, Simon D Fairbanks, Craig C Robertson, Jorge Bernardino de La Serna, Simon J Foster, James A Thomas
Ruthenium based antimicrobial theranostics - using nanoscopy to identify therapeutic targets and resistance mechanisms in Staphylococcus aureus. Chemical science 11 (1) (2019)
Kirsty L Smitten, Hannah M Southam, Jorge Bernardino de La Serna, Martin R Gill, Paul J Jarman, Carl G W Smythe, Robert K Poole, James A Thomas
Using Nanoscopy To Probe the Biological Activity of Antimicrobial Leads That Display Potent Activity against Pathogenic, Multidrug Resistant, Gram-Negative Bacteria. ACS nano 13 (5) (2019)
Sreejesh Sreedharan, Alessandro Sinopoli, Paul J Jarman, Darren Robinson, Christopher Clemmet, Paul A Scattergood, Craig R Rice, Carl G W Smythe, James A Thomas, Paul I P Elliott
Mitochondria-localising DNA-binding biscyclometalated phenyltriazole iridium(iii) dipyridophenazene complexes: syntheses and cellular imaging properties. Dalton transactions (Cambridge, England : 2003) 47 (14) (2018)
Sumit Kumar Pramanik, Sreejesh Sreedharan, Harwinder Singh, Mohsina Khan, Karishma Tiwari, Anjali Shiras, Carl Smythe, James A Thomas, Amitava Das
Mitochondria Targeting Non-Isocyanate-Based Polyurethane Nanocapsules for Enzyme-Triggered Drug Release. Bioconjugate chemistry 29 (11) (2018)
Sreejesh Sreedharan, Martin R Gill, Esther Garcia, Hiwa K Saeed, Darren Robinson, Aisling Byrne, Ashley Cadby, Tia E Keyes, Carl Smythe, Patrina Pellett, Jorge Bernardino de La Serna, James A Thomas
Multimodal Super-resolution Optical Microscopy Using a Transition-Metal-Based Probe Provides Unprecedented Capabilities for Imaging Both Nuclear Chromatin and Mitochondria. Journal of the American Chemical Society 139 (44) (2017)
Hiwa K Saeed, Paul J Jarman, Stuart Archer, Sreejesh Sreedharan, Ibrahim Q Saeed, Luke K Mckenzie, Julia A Weinstein, Niklaas J Buurma, Carl G W Smythe, James A Thomas
Homo- and Heteroleptic Phototoxic Dinuclear Metallo-Intercalators Based on RuII (dppn) Intercalating Moieties: Synthesis, Optical, and Biological Studies. Angewandte Chemie (International ed. in English) 56 (41) (2017)
Martin R Gill, Paul J Jarman, Swagata Halder, Michael G Walker, Hiwa K Saeed, James A Thomas, Carl Smythe, Kristijan Ramadan, Katherine A Vallis
A three-in-one-bullet for oesophageal cancer: replication fork collapse, spindle attachment failure and enhanced radiosensitivity generated by a ruthenium(ii) metallo-intercalator. Chemical science 9 (4) (2017)
Hiwa K Saeed, Ibrahim Q Saeed, Niklaas J Buurma, James A Thomas
The Structure of Linkers Affects the DNA Binding Properties of Tethered Dinuclear Ruthenium(II) Metallo-Intercalators. Chemistry (Weinheim an der Bergstrasse, Germany) 23 (23) (2017)
Firoj Ali, Sreejesh Sreedharan, Anila Hoskere Ashoka, Hiwa K Saeed, Carl G W Smythe, James A Thomas, Amitava Das
A Super-Resolution Probe To Monitor HNO Levels in the Endoplasmic Reticulum of Cells. Analytical chemistry 89 (22) (2017)
Michael G Walker, Paul J Jarman, Martin R Gill, Xiaohe Tian, Haslina Ahmad, Pattubala A N Reddy, Luke McKenzie, Julia A Weinstein, Anthony J H M Meijer, Giuseppe Battaglia, Carl G W Smythe, James A Thomas
A Self-Assembled Metallomacrocycle Singlet Oxygen Sensitizer for Photodynamic Therapy. Chemistry (Weinheim an der Bergstrasse, Germany) 22 (17) (2016)