Joachim Rudolph

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 11

Top Topics

Multiple Myeloma

Respiratory Syndrome Coronavirus

Top Venues

ACS chemical biology

Journal of medicinal chemistry

Cancer discovery

Nature biotechnology

This page only lists publications with an associated author ORCID identifier.

Publications

Marie-Gabrielle Braun, Avi Ashkenazi, Ramsay E Beveridge, Georgette Castanedo, Heidi Ackerly Wallweber, Maureen H Beresini, Kevin R Clark, Tom De Bruyn, Liqiang Fu, Paul Gibbons, Fan Jiang, Susan Kaufman, David Kan, James R Kiefer, Jean-Philippe Leclerc, Alexandre Lemire, Cuong Ly, Ehud Segal, Jessica Sims, Weiru Wang, Wentao Wei, Liang Zhao, Jacob B Schwarz, Joachim Rudolph
Discovery of Potent, Selective, and Orally Available IRE1α Inhibitors Demonstrating Comparable PD Modulation to IRE1 Knockdown in a Multiple Myeloma Model. Journal of medicinal chemistry (2024)
Marie-Gabrielle Braun, Avi Ashkenazi, Ramsay E Beveridge, Georgette Castanedo, Heidi Ackerly Wallweber, Maureen H Beresini, Kevin R Clark, Tom De Bruyn, Liqiang Fu, Paul Gibbons, Fan Jiang, Susan Kaufman, David Kan, James R Kiefer, Jean-Philippe Leclerc, Alexandre Lemire, Cuong Ly, Ehud Segal, Jessica Sims, Weiru Wang, Wentao Wei, Liang Zhao, Jacob B Schwarz, Joachim Rudolph
Discovery of Potent, Selective, and Orally Available IRE1α Inhibitors Demonstrating Comparable PD Modulation to IRE1 Knockdown in a Multiple Myeloma Model. Journal of medicinal chemistry 67 (11) (2024)
Ingo V Hartung, Joachim Rudolph, Mary M Mader, Monique P C Mulder, Paul Workman
Expanding Chemical Probe Space: Quality Criteria for Covalent and Degrader Probes. Journal of medicinal chemistry (2023)
Peter E Cockram, Benjamin T Walters, Aaron Lictao, Frances Shanahan, Ingrid E Wertz, Scott A Foster, Joachim Rudolph
Allosteric Inhibitors of the SARS-COV-2 Papain-like Protease Domain Induce Proteasomal Degradation of Its Parent Protein NSP3. ACS chemical biology 19 (1) (2023)
Peter E Cockram, Benjamin T Walters, Aaron Lictao, Frances Shanahan, Ingrid E Wertz, Scott A Foster, Joachim Rudolph
Allosteric Inhibitors of the SARS-COV-2 Papain-like Protease Domain Induce Proteasomal Degradation of Its Parent Protein NSP3. ACS chemical biology (2023)
Peter E Cockram, Benjamin T Walters, Aaron Lictao, Frances Shanahan, Ingrid E Wertz, Scott A Foster, Joachim Rudolph
Allosteric Inhibitors of the SARS-COV-2 Papain-like Protease Domain Induce Proteasomal Degradation of Its Parent Protein NSP3. ACS chemical biology 19 (1) (2023)
Mary M Mader, Joachim Rudolph, Ingo V Hartung, David E Uehling, Paul Workman, William J Zuercher
Which Small Molecule? Selecting Chemical Probes for Use in Cancer Research and Target Validation. Cancer discovery (2023)
Peter E Cockram, Benjamin T Walters, Aaron Lictao, Frances Shanahan, Ingrid E Wertz, Scott A Foster, Joachim Rudolph
Allosteric Inhibitors of the SARS-COV-2 Papain-like Protease Domain Induce Proteasomal Degradation of Its Parent Protein NSP3. ACS chemical biology 19 (1) (2023)
Christopher W Davies, Angela J Oh, Rana Mroue, Micah Steffek, John M Bruning, Yang Xiao, Siyu Feng, Sangeeta Jayakar, Emily Chan, Vidhyalakshmi Arumugam, Sean Carlo Uribe, Jake Drummond, Alexandra Frommlet, Cheng Lu, Yvonne Franke, Mark Merchant, Hartmut Koeppen, John G Quinn, Sushant Malhotra, Steve Do, Lewis Gazzard, Hans E Purkey, Joachim Rudolph, Melinda M Mulvihill, James T Koerber, Weiru Wang, Marie Evangelista
Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nature biotechnology 40 (5) (2022)
Joachim Rudolph, Jeff Settleman, Shiva Malek
Emerging Trends in Cancer Drug Discovery-From Drugging the "Undruggable" to Overcoming Resistance. Cancer discovery 11 (4) (2022)
Elena Ferri, Adrien Le Thomas, Heidi Ackerly Wallweber, Eric S Day, Benjamin T Walters, Susan E Kaufman, Marie-Gabrielle Braun, Kevin R Clark, Maureen H Beresini, Kyle Mortara, Yung-Chia A Chen, Breanna Canter, Wilson Phung, Peter S Liu, Alfred Lammens, Avi Ashkenazi, Joachim Rudolph, Weiru Wang
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands. Nature communications 11 (1) (2020)