Paul Workman

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 23

Top Topics

Fluorescence Imaging

Protein Protein

Prostate Cancer

Top Venues

Nucleic acids research

Cancer research

RSC medicinal chemistry

Scientific reports

This page only lists publications with an associated author ORCID identifier.

Publications

Patrizio Di Micco, Albert A Antolin, Costas Mitsopoulos, Eloy Villasclaras-Fernandez, Domenico Sanfelice, Daniela Dolciami, Pradeep Ramagiri, Ioan L Mica, Joseph E Tym, Philip W Gingrich, Huabin Hu, Paul Workman, Bissan Al-Lazikani
canSAR: update to the cancer translational research and drug discovery knowledgebase. Nucleic acids research 51 (D1) (2023)
Patrizio Di Micco, Albert A Antolin, Costas Mitsopoulos, Eloy Villasclaras-Fernandez, Domenico Sanfelice, Daniela Dolciami, Pradeep Ramagiri, Ioan L Mica, Joseph E Tym, Philip W Gingrich, Huabin Hu, Paul Workman, Bissan Al-Lazikani
canSAR: update to the cancer translational research and drug discovery knowledgebase. Nucleic acids research 51 (D1) (2023)
A Elisa Pasqua, Swee Y Sharp, Nicola E A Chessum, Angela Hayes, Loredana Pellegrino, Michael J Tucker, Asadh Miah, Birgit Wilding, Lindsay E Evans, Carl S Rye, Ngai Yi Mok, Manjuan Liu, Alan T Henley, Sharon Gowan, Emmanuel De Billy, Robert Te Poele, Marissa Powers, Suzanne A Eccles, Paul Andrew Clarke, Florence I Raynaud, Paul Workman, Keith Jones, Matthew D Cheeseman
HSF1 Pathway Inhibitor Clinical Candidate (CCT361814/NXP800) Developed from a Phenotypic Screen as a Potential Treatment for Refractory Ovarian Cancer and Other Malignancies. Journal of medicinal chemistry (2023)
Patrizio Di Micco, Albert A Antolin, Costas Mitsopoulos, Eloy Villasclaras-Fernandez, Domenico Sanfelice, Daniela Dolciami, Pradeep Ramagiri, Ioan L Mica, Joseph E Tym, Philip W Gingrich, Huabin Hu, Paul Workman, Bissan Al-Lazikani
canSAR: update to the cancer translational research and drug discovery knowledgebase. Nucleic acids research 51 (D1) (2023)
Mary M Mader, Joachim Rudolph, Ingo V Hartung, David E Uehling, Paul Workman, William J Zuercher
Which Small Molecule? Selecting Chemical Probes for Use in Cancer Research and Target Validation. Cancer discovery (2023)
Paul Workman
The NCI-60 Human Tumor Cell Line Screen: A Catalyst for Progressive Evolution of Models for Discovery and Development of Cancer Drugs. Cancer research 83 (19) (2023)
Marco P Licciardello, Paul Workman
The era of high-quality chemical probes. RSC medicinal chemistry 13 (12) (2022)
Marco P Licciardello, Paul Workman
The era of high-quality chemical probes. RSC medicinal chemistry 13 (12) (2022)
Albert A Antolin, Domenico Sanfelice, Alisa Crisp, Eloy Villasclaras Fernandez, Ioan L Mica, Yi Chen, Ian Collins, Aled Edwards, Susanne Müller, Bissan Al-Lazikani, Paul Workman
The Chemical Probes Portal: an expert review-based public resource to empower chemical probe assessment, selection and use. Nucleic acids research (2022)
Abhijit Pal, Rajiv Shinde, Manuel Selvi Miralles, Paul Workman, Johann S de Bono
Applications of liquid biopsy in the Pharmacological Audit Trail for anticancer drug development. Nature reviews. Clinical oncology 18 (7) (2021)
Pietro Carotenuto, Francesco Amato, Andrea Lampis, Colin Rae, Somaieh Hedayat, Maria C Previdi, Domenico Zito, Maya Raj, Vincenza Guzzardo, Francesco Sclafani, Andrea Lanese, Claudia Parisi, Caterina Vicentini, Ian Said-Huntingford, Jens C Hahne, Albert Hallsworth, Vladimir Kirkin, Kate Young, Ruwaida Begum, Andrew Wotherspoon, Kyriakos Kouvelakis, Sergio Xavier Azevedo, Vasiliki Michalarea, Rosanna Upstill-Goddard, Sheela Rao, David Watkins, Naureen Starling, Anguraj Sadanandam, David K Chang, Andrew V Biankin, Nigel B Jamieson, Aldo Scarpa, David Cunningham, Ian Chau, Paul Workman, Angelo Paolo Dei Tos, Nicola Valeri, Chiara Braconi
Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage. Nature communications 12 (1) (2021)
Veronica S Gil, Susana Miranda, Ruth Riisnaes, Bora Gurel, Mariantonietta D'Ambrosio, Alessandro Vasciaveo, Mateus Crespo, Ana Ferreira, Daniela Brina, Martina Troiani, Adam Sharp, Beshara Sheehan, Rossitza Christova, George Seed, Ines Figueiredo, Maryou Lambros, David Dolling, Jan Rekowski, Abdullah Alajati, Matthew Clarke, Rita Pereira, Penelope Ruth Flohr, Gemma Fowler, Gunther Boysen, Semini Sumanasuriya, Diletta Bianchini, Pasquale Rescigno, Caterina Aversa, Nina Tunariu, Christina Guo, Alec Paschalis, Claudia Bertan, Lorenzo Buroni, Jian Ning, Suzanne Carreira, Paul Workman, Amanda Swain, Andrea Califano, Michael M Shen, Andrea Alimonti, Antje J Neeb, Stand Up To Cancer International Prostate Cancer Dream Team, Jonathan Welti, Wei Yuan, Johann S de Bono
HER3 is an Actionable Target in Advanced Prostate Cancer. Cancer research (2021)
Rebecca F Rogers, Michael I Walton, Daniel L Cherry, Ian Collins, Paul Andrew Clarke, Michelle D Garrett, Paul Workman
CHK1 Inhibition Is Synthetically Lethal with Loss of B-Family DNA Polymerase Function in Human Lung and Colorectal Cancer Cells. Cancer research 80 (8) (2020)
John F Darby, Lewis R Vidler, Peter J Simpson, Bissan Al-Lazikani, Stephen J Matthews, Swee Y Sharp, Laurence H Pearl, Swen Hoelder, Paul Workman
Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches. Scientific reports 10 (1) (2020)
Albert A Antolin, Malaka Ameratunga, Udai Banerji, Paul Andrew Clarke, Paul Workman, Bissan Al-Lazikani
The kinase polypharmacology landscape of clinical PARP inhibitors. Scientific reports 10 (1) (2020)
Chi Zhang, Simon R Stockwell, May Elbanna, Robin Ketteler, Jamie Freeman, Bissan Al-Lazikani, Suzanne Eccles, Alexis De Haven Brandon, Florence Raynaud, Angela Hayes, Paul Andrew Clarke, Paul Workman, Sibylle Mittnacht
Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases. Oncogene 38 (30) (2019)
Albert A Antolin, Paul Workman, Bissan Al-Lazikani
Public resources for chemical probes: the journey so far and the road ahead. Future medicinal chemistry 13 (8) (2019)
Catarina Felisberto-Rodrigues, Jemima C Thomas, Peter Craig McAndrew, Yann-Vaï Le Bihan, Rosemary Burke, Paul Workman, Rob L M van Montfort
Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release. The Biochemical journal 476 (18) (2019)
Paul Workman, Albert A Antolin, Bissan Al-Lazikani
Transforming cancer drug discovery with Big Data and AI. Expert opinion on drug discovery 14 (11) (2019)
Susan Slovin, Syed Hussain, Fred Saad, Jorge Garcia, Joel Picus, Roberta Ferraldeschi, Mateus Crespo, Penelope Flohr, Ruth Riisnaes, Chihche Lin, Harold Keer, Aram Oganesian, Paul Workman, Johann de Bono
Pharmacodynamic and Clinical Results from a Phase I/II Study of the HSP90 Inhibitor Onalespib in Combination with Abiraterone Acetate in Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (15) (2019)
Nicola E A Chessum, Swee Y Sharp, John J Caldwell, A Elisa Pasqua, Birgit Wilding, Giampiero Colombano, Ian Collins, Bugra Ozer, Meirion Richards, Martin Rowlands, Mark Stubbs, Rosemary Burke, P Craig McAndrew, Paul Andrew Clarke, Paul Workman, Matthew D Cheeseman, Keith Jones
Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766). Journal of medicinal chemistry 61 (3) (2018)
Georgios Vlachogiannis, Somaieh Hedayat, Alexandra Vatsiou, Yann Jamin, Javier Fernández-Mateos, Khurum Khan, Andrea Lampis, Katherine Eason, Ian Huntingford, Rosemary Burke, Mihaela Rata, Dow-Mu Koh, Nina Tunariu, David Collins, Sanna Hulkki-Wilson, Chanthirika Ragulan, Inmaculada Spiteri, Sing Yu Moorcraft, Ian Chau, Sheela Rao, David Watkins, Nicos Fotiadis, Maria Antonietta Bali, Mahnaz Darvish Damavandi, Hazel Lote, Zakaria Eltahir, Elizabeth C Smyth, Ruwaida Begum, Paul Andrew Clarke, Jens C Hahne, Mitchell Dowsett, Johann de Bono, Paul Workman, Anguraj Sadanandam, Angelo Paolo Dei Tos, Owen J Sansom, Suzanne Eccles, Naureen Starling, Chiara Braconi, Andrea Sottoriva, Simon P Robinson, David Cunningham, Nicola Valeri
Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Science (New York, N.Y.) 359 (6378) (2018)
Paul Andrew Clarke, Maria-Jesus Ortiz-Ruiz, Robert TePoele, Olajumoke Adeniji-Popoola, Gary Box, Will Court, Stephanie Czasch, Samer El Bawab, Christina Esdar, Ken Ewan, Sharon Gowan, Alexis De Haven Brandon, Phillip Hewitt, Stephen M Hobbs, Wolfgang Kaufmann, Aurélie Mallinger, Florence Raynaud, Toby Roe, Felix Rohdich, Kai Schiemann, Stephanie Simon, Richard Schneider, Melanie Valenti, Stefan Weigt, Julian Blagg, Andree Blaukat, Trevor C Dale, Suzanne A Eccles, Stefan Hecht, Klaus Urbahns, Paul Workman, Dirk Wienke
Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases. eLife 5 (2016)