John A Katzenellenbogen

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 28

Top Topics

Molecular Dynamics Simulations

Estrogen Receptor

Endoplasmic Reticulum

Signaling Pathway

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

ACS chemical biology

Nature communications

Science signaling

This page only lists publications with an associated author ORCID identifier.

Publications

Charles K Min, Jerome C Nwachukwu, Yingwei Hou, Robin J Russo, Alexandra Papa, Jian Min, Rouming Peng, Sung Hoon Kim, Yvonne S Ziegler, Erumbi S Rangarajan, Tina Izard, Benita S Katzenellenbogen, John A Katzenellenbogen, Kendall W Nettles
Asymmetric allostery in estrogen receptor-α homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proceedings of the National Academy of Sciences of the United States of America 121 (24) (2024)
Charles K Min, Jerome C Nwachukwu, Yingwei Hou, Robin J Russo, Alexandra Papa, Jian Min, Rouming Peng, Sung Hoon Kim, Yvonne S Ziegler, Erumbi S Rangarajan, Tina Izard, Benita S Katzenellenbogen, John A Katzenellenbogen, Kendall W Nettles
Asymmetric allostery in estrogen receptor-α homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proceedings of the National Academy of Sciences of the United States of America 121 (24) (2024)
Charles K Min, Jerome C Nwachukwu, Yingwei Hou, Robin J Russo, Alexandra Papa, Jian Min, Rouming Peng, Sung Hoon Kim, Yvonne S Ziegler, Erumbi S Rangarajan, Tina Izard, Benita S Katzenellenbogen, John A Katzenellenbogen, Kendall W Nettles
Asymmetric allostery in estrogen receptor-α homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proceedings of the National Academy of Sciences of the United States of America 121 (24) (2024)
Charles K Min, Jerome C Nwachukwu, Yingwei Hou, Robin J Russo, Alexandra Papa, Jian Min, Rouming Peng, Sung Hoon Kim, Yvonne S Ziegler, Erumbi S Rangarajan, Tina Izard, Benita S Katzenellenbogen, John A Katzenellenbogen, Kendall W Nettles
Asymmetric allostery in estrogen receptor-α homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proceedings of the National Academy of Sciences of the United States of America 121 (24) (2024)
Charles K Min, Jerome C Nwachukwu, Yingwei Hou, Robin J Russo, Alexandra Papa, Jian Min, Rouming Peng, Sung Hoon Kim, Yvonne S Ziegler, Erumbi S Rangarajan, Tina Izard, Benita S Katzenellenbogen, John A Katzenellenbogen, Kendall W Nettles
Asymmetric allostery in estrogen receptor-α homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proceedings of the National Academy of Sciences of the United States of America 121 (24) (2024)
Charles K Min, Jerome C Nwachukwu, Yingwei Hou, Robin J Russo, Alexandra Papa, Jian Min, Rouming Peng, Sung Hoon Kim, Yvonne S Ziegler, Erumbi S Rangarajan, Tina Izard, Benita S Katzenellenbogen, John A Katzenellenbogen, Kendall W Nettles
Asymmetric allostery in estrogen receptor-α homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proceedings of the National Academy of Sciences of the United States of America 121 (24) (2024)
Belinda Kingston, Alex Pearson, Maria Teresa Herrera-Abreu, Li-Xuan Sim, Rosalind J Cutts, Heena Shah, Laura Moretti, Lucy Suzanne Kilburn, Hannah Johnson, Iain R J Macpherson, Alistair Ring, Judith M Bliss, Yingwei Hou, Weiyi Toy, John A Katzenellenbogen, Sarat Chandarlapaty, Nicholas C Turner
ESR1 F404 mutations and acquired resistance to fulvestrant in ESR1 mutant breast cancer. Cancer discovery (2023)
John A Katzenellenbogen
Stringing along the estrogen receptor to engage with DNA. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Anastasia Sacharidou, Ken Chambliss, Jun Peng, Jose Barrera, Keiji Tanigaki, Katherine Luby-Phelps, İpek Özdemir, Sohaib Khan, Shashank R Sirsi, Sung Hoon Kim, Benita S Katzenellenbogen, John A Katzenellenbogen, Mohammed Kanchwala, Adwait A Sathe, Andrew Lemoff, Chao Xing, Kenneth Hoyt, Chieko Mineo, Philip W Shaul
Endothelial ERα promotes glucose tolerance by enhancing endothelial insulin transport to skeletal muscle. Nature communications 14 (1) (2023)
John A Katzenellenbogen
Stringing along the estrogen receptor to engage with DNA. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Yan Cheng, Fumou Sun, Krista Thornton, Xuefang Jing, Jing Dong, Grant Yun, Michael Pisano, Fenghuang Zhan, Sung Hoon Kim, John A Katzenellenbogen, Benita S Katzenellenbogen, Parameswaran Hari, Siegfried Janz
FOXM1 regulates glycolysis and energy production in multiple myeloma. Oncogene 41 (32) (2022)
Miriam Doepner, Inyoung Lee, Christopher A Natale, Roderick Brathwaite, Swati Venkat, Sung Hoon Kim, Yiliang Wei, Christopher R Vakoc, Brian C Capell, John A Katzenellenbogen, Benita S Katzenellenbogen, Michael E Feigin, Todd W Ridky
Endogenous DOPA inhibits melanoma through suppression of CHRM1 signaling. Science advances 8 (35) (2022)
Dong Zhou, Huaping Chen, Cedric Mpoy, Sadia Afrin, Buck E Rogers, Joel R Garbow, John A Katzenellenbogen, Jinbin Xu
Radiosynthesis and Evaluation of Talazoparib and Its Derivatives as PARP-1-Targeting Agents. Biomedicines 9 (5) (2021)
Qian-Ying Zuo, Karen L Chen, Alicia Arredondo Eve, Yu-Jeh Liu, Sung Hoon Kim, Benita S Katzenellenbogen, John A Katzenellenbogen, Zeynep Madak Erdogan
Pathway Preferential Estrogens Prevent Hepatosteatosis Due to Ovariectomy and High-Fat Diets. Nutrients 13 (10) (2021)
Jian Min, Jerome C Nwachukwu, Charles K Min, Jacqline W Njeri, Sathish Srinivasan, Erumbi S Rangarajan, Charles C Nettles, Valeria Sanabria Guillen, Yvonne S Ziegler, Shunchao Yan, Kathryn E Carlson, Yingwei Hou, Sung Hoon Kim, Scott J Novick, Bruce D Pascal, Rene Houtman, Patrick R Griffin, Tina Izard, Benita S Katzenellenbogen, John A Katzenellenbogen, Kendall W Nettles
Dual-mechanism estrogen receptor inhibitors. Proceedings of the National Academy of Sciences of the United States of America 118 (35) (2021)
Farrokh Dehdashti, Ningying Wu, Cynthia X Ma, Michael J Naughton, John A Katzenellenbogen, Barry A Siegel
Association of PET-based estradiol-challenge test for breast cancer progesterone receptors with response to endocrine therapy. Nature communications 12 (1) (2021)
Christopher G Mayne, Weiyi Toy, Kathryn E Carlson, Trusha Bhatt, Sean W Fanning, Geoffrey L Greene, Benita S Katzenellenbogen, Sarat Chandarlapaty, John A Katzenellenbogen, Emad Tajkhorshid
Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer. Molecular cancer research : MCR 19 (9) (2021)
Yvonne Ziegler, Valeria Sanabria Guillen, Sung Hoon Kim, John A Katzenellenbogen, Benita S Katzenellenbogen
Transcription Regulation and Genome Rewiring Governing Sensitivity and Resistance to FOXM1 Inhibition in Breast Cancer. Cancers 13 (24) (2021)
Yin Li, Laurel A Coons, Rene Houtman, Kathryn E Carlson, Teresa A Martin, Christopher G Mayne, Diana Melchers, Tanner B Jefferson, J Tyler Ramsey, John A Katzenellenbogen, Kenneth S Korach
A mutant form of ERα associated with estrogen insensitivity affects the coupling between ligand binding and coactivator recruitment. Science signaling 13 (650) (2020)
Parama Dey, Alexander Wang, Yvonne Ziegler, Sung Hoon Kim, Dorraya El-Ashry, John A Katzenellenbogen, Benita S Katzenellenbogen
Suppression of Tumor Growth, Metastasis, and Signaling Pathways by Reducing FOXM1 Activity in Triple Negative Breast Cancer. Cancers 12 (9) (2020)
Zeynep Madak-Erdogan, Shoham Band, Yiru C Zhao, Rebecca Lee Smith, Eylem Kulkoyluoglu-Cotul, Qianying Zuo, Ashlie Santaliz Casiano, Kinga Wrobel, Gianluigi Rossi, Sung Hoon Kim, John A Katzenellenbogen, Mariah L Johnson, Meera Patel, Natascia Marino, Anna Maria V Storniolo, Jodi A Flaws
Free Fatty Acids Rewire Cancer Metabolism in Obesity-Associated Breast Cancer via Estrogen Receptor and mTOR Signaling. Cancer research 79 (10) (2019)
John A Katzenellenbogen, Christopher G Mayne, Benita S Katzenellenbogen, Geoffrey L Greene, Sarat Chandarlapaty
Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance. Nature reviews. Cancer 18 (6) (2019)
Sirish K Ippagunta, Julie A Pollock, Naina Sharma, Wenwei Lin, Taosheng Chen, Kazuki Tawaratsumida, Anthony A High, Jaeki Min, Yizhe Chen, R Kiplin Guy, Vanessa Redecke, John A Katzenellenbogen, Hans Häcker
Identification of Toll-like receptor signaling inhibitors based on selective activation of hierarchically acting signaling proteins. Science signaling 11 (543) (2018)
Sean W Fanning, Rinath Jeselsohn, Venkatasubramanian Dharmarajan, Christopher G Mayne, Mostafa Karimi, Gilles Buchwalter, René Houtman, Weiyi Toy, Colin E Fowler, Ross Han, Muriel Lainé, Kathryn E Carlson, Teresa A Martin, Jason Nowak, Jerome C Nwachukwu, David J Hosfield, Sarat Chandarlapaty, Emad Tajkhorshid, Kendall W Nettles, Patrick R Griffin, Yang Shen, John A Katzenellenbogen, Myles A Brown, Geoffrey L Greene
The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells. eLife 7 (2018)
Julie A Pollock, Naina Sharma, Sirish K Ippagunta, Vanessa Redecke, Hans Häcker, John A Katzenellenbogen
Triaryl Pyrazole Toll-Like Receptor Signaling Inhibitors: Structure-Activity Relationships Governing Pan- and Selective Signaling Inhibitors. ChemMedChem 13 (20) (2018)
Abhishek Sharma, Weiyi Toy, Valeria Sanabria Guillen, Naina Sharma, Jian Min, Kathryn E Carlson, Christopher G Mayne, Shengjia Lin, Michael Sabio, Geoffrey Greene, Benita S Katzenellenbogen, Sarat Chandarlapaty, John A Katzenellenbogen
Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain. ACS chemical biology 13 (12) (2018)
Jian Min, Valeria Sanabria Guillen, Abhishek Sharma, Yuechao Zhao, Yvonne Ziegler, Ping Gong, Christopher G Mayne, Sathish Srinivasan, Sung Hoon Kim, Kathryn E Carlson, Kendall W Nettles, Benita S Katzenellenbogen, John A Katzenellenbogen
Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells. Journal of medicinal chemistry 60 (14) (2017)
Naina Sharma, Kathryn E Carlson, Jerome C Nwachukwu, Sathish Srinivasan, Abhishek Sharma, Kendall W Nettles, John A Katzenellenbogen
Exploring the Structural Compliancy versus Specificity of the Estrogen Receptor Using Isomeric Three-Dimensional Ligands. ACS chemical biology 12 (2) (2016)