John S Lazo

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 23

Top Venues

The Journal of pharmacology and experimental therapeutics

Biomolecules

Nature medicine

ACS infectious diseases

University of Virginia

University of Michigan (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Virginia Jan 01 2011

United States

Professor :: Pharmacology & Chemistry

Education History

University of Michigan Jun 01 1971 - May 01 1976

United States

PHD :: Pharmacology

Publications

Alondra Vázquez Rivera, Heather Donald, Mounia Alaoui-El-Azher, John J Skoko, John S Lazo, Michael A Parniak, Paul A Johnston, Nicolas Sluis-Cremer
Discovery of Benzisothiazolone Derivatives as Bifunctional Inhibitors of HIV-1 Reverse Transcriptase DNA Polymerase and Ribonuclease H Activities. Biomolecules 14 (7) (2024)
Pavel A Solopov, Ruben Manuel Luciano Colunga Biancatelli, Tierney Day, Betsy Gregory, Elizabeth R Sharlow, John S Lazo, John D Catravas
KVX-053, a Protein Tyrosine Phosphatase 4A3 inhibitor, ameliorates SARS-CoV-2 Spike protein subunit 1 - induced acute lung injury in mice. The Journal of pharmacology and experimental therapeutics (2024)
Alondra Vázquez Rivera, Heather Donald, Mounia Alaoui-El-Azher, John J Skoko, John S Lazo, Michael A Parniak, Paul A Johnston, Nicolas Sluis-Cremer
Discovery of Benzisothiazolone Derivatives as Bifunctional Inhibitors of HIV-1 Reverse Transcriptase DNA Polymerase and Ribonuclease H Activities. Biomolecules 14 (7) (2024)
Chirayu R Chokshi, Muhammad Vaseem Shaikh, Benjamin Brakel, Martin A Rossotti, David Tieu, William Maich, Alisha Anand, Shawn C Chafe, Kui Zhai, Yujin Suk, Agata M Kieliszek, Petar Miletic, Nicholas Mikolajewicz, David Chen, Jamie D McNicol, Katherine Chan, Amy H Y Tong, Laura Kuhlmann, Lina Liu, Zahra Alizada, Daniel Mobilio, Nazanin Tatari, Neil Savage, Nikoo Aghaei, Shan Grewal, Anish Puri, Minomi Subapanditha, Dillon McKenna, Vladimir Ignatchenko, Joseph M Salamoun, Jacek M Kwiecien, Peter Wipf, Elizabeth R Sharlow, John P Provias, Jian-Qiang Lu, John S Lazo, Thomas Kislinger, Yu Lu, Kevin R Brown, Chitra Venugopal, Kevin A Henry, Jason Moffat, Sheila K Singh
Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells. Nature medicine (2024)
Chirayu R Chokshi, Muhammad Vaseem Shaikh, Benjamin Brakel, Martin A Rossotti, David Tieu, William Maich, Alisha Anand, Shawn C Chafe, Kui Zhai, Yujin Suk, Agata M Kieliszek, Petar Miletic, Nicholas Mikolajewicz, David Chen, Jamie D McNicol, Katherine Chan, Amy H Y Tong, Laura Kuhlmann, Lina Liu, Zahra Alizada, Daniel Mobilio, Nazanin Tatari, Neil Savage, Nikoo Aghaei, Shan Grewal, Anish Puri, Minomi Subapanditha, Dillon McKenna, Vladimir Ignatchenko, Joseph M Salamoun, Jacek M Kwiecien, Peter Wipf, Elizabeth R Sharlow, John P Provias, Jian-Qiang Lu, John S Lazo, Thomas Kislinger, Yu Lu, Kevin R Brown, Chitra Venugopal, Kevin A Henry, Jason Moffat, Sheila K Singh
Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells. Nature medicine (2024)
Alondra Vázquez Rivera, Heather Donald, Mounia Alaoui-El-Azher, John J Skoko, John S Lazo, Michael A Parniak, Paul A Johnston, Nicolas Sluis-Cremer
Discovery of Benzisothiazolone Derivatives as Bifunctional Inhibitors of HIV-1 Reverse Transcriptase DNA Polymerase and Ribonuclease H Activities. Biomolecules 14 (7) (2024)
John S Lazo, Kelly N Isbell, Sai Ashish Vasa, Danielle C Llaneza, Garnett A Mingledorff, Elizabeth R Sharlow
Deletion of PTP4A3 phosphatase in high grade serous ovarian cancer cells decreases tumorigenicity and produces marked changes in intracellular signaling pathways and cytokine release. The Journal of pharmacology and experimental therapeutics (2024)
Alondra Vázquez Rivera, Heather Donald, Mounia Alaoui-El-Azher, John J Skoko, John S Lazo, Michael A Parniak, Paul A Johnston, Nicolas Sluis-Cremer
Discovery of Benzisothiazolone Derivatives as Bifunctional Inhibitors of HIV-1 Reverse Transcriptase DNA Polymerase and Ribonuclease H Activities. Biomolecules 14 (7) (2024)
John S Lazo, Kelly N Isbell, Sai Ashish Vasa, Danielle C Llaneza, Ettore J Rastelli, Peter Wipf, Elizabeth R Sharlow
Disruption of Ovarian Cancer STAT3 and p38 Signaling with a Small-Molecule Inhibitor of PTP4A3 Phosphatase. The Journal of pharmacology and experimental therapeutics 384 (3) (2023)
John S Lazo, Kelly N Isbell, Sai Ashish Vasa, Danielle C Llaneza, Ettore J Rastelli, Peter Wipf, Elizabeth R Sharlow
Disruption of Ovarian Cancer STAT3 and p38 Signaling with a Small-Molecule Inhibitor of PTP4A3 Phosphatase. The Journal of pharmacology and experimental therapeutics 384 (3) (2023)
John S Lazo, Kelly N Isbell, Sai Ashish Vasa, Danielle C Llaneza, Ettore J Rastelli, Peter Wipf, Elizabeth R Sharlow
Disruption of Ovarian Cancer STAT3 and p38 Signaling with a Small-Molecule Inhibitor of PTP4A3 Phosphatase. The Journal of pharmacology and experimental therapeutics 384 (3) (2023)
John S Lazo, Kelly N Isbell, Sai Ashish Vasa, Danielle C Llaneza, Ettore J Rastelli, Peter Wipf, Elizabeth R Sharlow
Disruption of Ovarian Cancer STAT3 and p38 Signaling with a Small-Molecule Inhibitor of PTP4A3 Phosphatase. The Journal of pharmacology and experimental therapeutics 384 (3) (2023)
John S Lazo, Kelly N Isbell, Sai Ashish Vasa, Danielle C Llaneza, Ettore J Rastelli, Peter Wipf, Elizabeth R Sharlow
Disruption of Ovarian Cancer STAT3 and p38 Signaling with a Small-Molecule Inhibitor of PTP4A3 Phosphatase. The Journal of pharmacology and experimental therapeutics 384 (3) (2023)
John S Lazo, Kelly N Isbell, Sai Ashish Vasa, Danielle C Llaneza, Ettore J Rastelli, Peter Wipf, Elizabeth R Sharlow
Disruption of ovarian cancer STAT3 and p38 signaling with a small molecule inhibitor of PTP4A3 phosphatase. The Journal of pharmacology and experimental therapeutics (2023)
John S Lazo, Kelly N Isbell, Sai Ashish Vasa, Danielle C Llaneza, Ettore J Rastelli, Peter Wipf, Elizabeth R Sharlow
Disruption of ovarian cancer STAT3 and p38 signaling with a small molecule inhibitor of PTP4A3 phosphatase. The Journal of pharmacology and experimental therapeutics (2023)
John S Lazo, Kelly N Isbell, Sai Ashish Vasa, Danielle C Llaneza, Ettore J Rastelli, Peter Wipf, Elizabeth R Sharlow
Disruption of Ovarian Cancer STAT3 and p38 Signaling with a Small-Molecule Inhibitor of PTP4A3 Phosphatase. The Journal of pharmacology and experimental therapeutics 384 (3) (2023)
John S Lazo, Elizabeth R Sharlow, Robert Cornelison, Duncan J Hart, Danielle C Llaneza, Anna J Mendelson, Ettore J Rastelli, Nikhil R Tasker, Charles N Landen, Peter Wipf
Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer. Biomolecules 11 (7) (2021)
Diana Caridha, Richard J Sciotti, Jason Sousa, Brian Vesely, Tesfaye Teshome, Gustave Bonkoungou, Chau Vuong, Susan Leed, Mozna Khraiwesh, Erica Penn, Mara Kreishman-Deitrick, Patricia Lee, Brandon Pybus, John S Lazo, Elizabeth R Sharlow
Combination of Subtherapeutic Doses of Tretazicar and Liposomal Amphotericin B Suppresses and Cures Leishmania major-Induced Cutaneous Lesions in Murine Models. ACS infectious diseases 7 (2) (2021)
Mateusz P Czub, Adam M Boulton, Ettore J Rastelli, Nikhil R Tasker, Taber S Maskrey, Isabella K Blanco, Kelley E McQueeney, John H Bushweller, Wladek Minor, Peter Wipf, Elizabeth R Sharlow, John S Lazo
Structure of the Complex of an Iminopyridinedione Protein Tyrosine Phosphatase 4A3 Phosphatase Inhibitor with Human Serum Albumin. Molecular pharmacology 98 (6) (2020)
Oscar Aguilar-Sopeña, Sara Hernández-Pérez, Sergio Alegre-Gómez, Patricia Castro-Sánchez, Alba Iglesias-Ceacero, John S Lazo, Pedro Roda-Navarro
Effect of Pharmacological Inhibition of the Catalytic Activity of Phosphatases of Regenerating Liver in Early T Cell Receptor Signaling Dynamics and IL-2 Production. International journal of molecular sciences 21 (7) (2020)
John S Lazo, Isabella K Blanco, Nikhil R Tasker, Ettore J Rastelli, James C Burnett, Sharon R Garrott, Duncan J Hart, Rebecca L McCloud, Ku-Lung Hsu, Peter Wipf, Elizabeth R Sharlow
Next-Generation Cell-Active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase. The Journal of pharmacology and experimental therapeutics 371 (3) (2019)
John S Lazo
The hubris and humility of cancer pharmacology in the post immuno-oncology era. Pharmacology research & perspectives 7 (6) (2019)
John S Lazo
Cutting down the time to identify challenging tumor therapeutic targets and drug combinations using synthetic lethal approaches. F1000Research 7 (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

John S Lazo