Ku-Lung Hsu

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 27

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature chemical biology

Chembiochem : a European journal of chemical biology

RSC chemical biology

University of Virginia

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Virginia

United States

Assistant Professor :: Chemistry and Pharmacology

Publications

R Justin Grams, Kun Yuan, Michael W Founds, Madeleine L Ware, Michael G Pilar, Ku-Lung Hsu
Imidazoles are Tunable Nucleofuges for Developing Tyrosine-Reactive Electrophiles. Chembiochem : a European journal of chemical biology 25 (16) (2024)
R Justin Grams, Kun Yuan, Michael W Founds, Madeleine L Ware, Michael G Pilar, Ku-Lung Hsu
Imidazoles are Tunable Nucleofuges for Developing Tyrosine-Reactive Electrophiles. Chembiochem : a European journal of chemical biology (2024)
R Justin Grams, Kun Yuan, Michael W Founds, Madeleine L Ware, Michael G Pilar, Ku-Lung Hsu
Imidazoles are Tunable Nucleofuges for Developing Tyrosine-Reactive Electrophiles. Chembiochem : a European journal of chemical biology 25 (16) (2024)
Miaomiao Chen, Myungsun Shin, Timothy B Ware, Giulia Donvito, Karan H Muchhala, Ryan Mischel, Mohammed A Mustafa, Vlad Serbulea, Clint M Upchurch, Norbert Leitinger, Hamid I Akbarali, Aron H Lichtman, Ku-Lung Hsu
Endocannabinoid biosynthetic enzymes regulate pain response via LKB1-AMPK signaling. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
Anthony M Ciancone, Kyung W Seo, Miaomiao Chen, Adam L Borne, Adam H Libby, Dina L Bai, Ralph E Kleiner, Ku-Lung Hsu
Global Discovery of Covalent Modulators of Ribonucleoprotein Granules. Journal of the American Chemical Society (2023)
Roberto Mendez, Minhaj Shaikh, Michael C Lemke, Kun Yuan, Adam H Libby, Dina L Bai, Mark M Ross, Thurl E Harris, Ku-Lung Hsu
Predicting small molecule binding pockets on diacylglycerol kinases using chemoproteomics and AlphaFold. RSC chemical biology 4 (6) (2023)
Miaomiao Chen, Myungsun Shin, Timothy B Ware, Giulia Donvito, Karan H Muchhala, Ryan Mischel, Mohammed A Mustafa, Vlad Serbulea, Clint M Upchurch, Norbert Leitinger, Hamid I Akbarali, Aron H Lichtman, Ku-Lung Hsu
Endocannabinoid biosynthetic enzymes regulate pain response via LKB1-AMPK signaling. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
Miaomiao Chen, Myungsun Shin, Timothy B Ware, Giulia Donvito, Karan H Muchhala, Ryan Mischel, Mohammed A Mustafa, Vlad Serbulea, Clint M Upchurch, Norbert Leitinger, Hamid I Akbarali, Aron H Lichtman, Ku-Lung Hsu
Endocannabinoid biosynthetic enzymes regulate pain response via LKB1-AMPK signaling. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
Andrew J Heindel, Jeffrey W Brulet, Xiantao Wang, Michael W Founds, Adam H Libby, Dina L Bai, Michael C Lemke, David M Leace, Thurl E Harris, Markus Hafner, Ku-Lung Hsu
Chemoproteomic capture of RNA binding activity in living cells. Nature communications 14 (1) (2023)
Miaomiao Chen, Myungsun Shin, Timothy B Ware, Giulia Donvito, Karan H Muchhala, Ryan Mischel, Mohammed A Mustafa, Vlad Serbulea, Clint M Upchurch, Norbert Leitinger, Hamid I Akbarali, Aron H Lichtman, Ku-Lung Hsu
Endocannabinoid biosynthetic enzymes regulate pain response via LKB1-AMPK signaling. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
Miaomiao Chen, Myungsun Shin, Timothy B Ware, Giulia Donvito, Karan H Muchhala, Ryan Mischel, Mohammed A Mustafa, Vlad Serbulea, Clint M Upchurch, Norbert Leitinger, Hamid I Akbarali, Aron H Lichtman, Ku-Lung Hsu
Endocannabinoid biosynthetic enzymes regulate pain response via LKB1-AMPK signaling. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
Miaomiao Chen, Myungsun Shin, Timothy B Ware, Giulia Donvito, Karan H Muchhala, Ryan Mischel, Mohammed A Mustafa, Vlad Serbulea, Clint M Upchurch, Norbert Leitinger, Hamid I Akbarali, Aron H Lichtman, Ku-Lung Hsu
Endocannabinoid biosynthetic enzymes regulate pain response via LKB1-AMPK signaling. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
Miaomiao Chen, Myungsun Shin, Timothy B Ware, Giulia Donvito, Karan H Muchhala, Ryan Mischel, Mohammed A Mustafa, Vlad Serbulea, Clint M Upchurch, Norbert Leitinger, Hamid I Akbarali, Aron H Lichtman, Ku-Lung Hsu
Endocannabinoid biosynthetic enzymes regulate pain response via LKB1-AMPK signaling. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
R Justin Grams, Ku-Lung Hsu
Catch your breath. Nature chemical biology 18 (7) (2022)
Tao Huang, Seyyedmohsen Hosseinibarkooie, Adam L Borne, Mitchell E Granade, Jeffrey W Brulet, Thurl E Harris, Heather A Ferris, Ku-Lung Hsu
Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chemical science 12 (9) (2021)
Rebecca L McCloud, Kun Yuan, Keira E Mahoney, Dina L Bai, Jeffrey Shabanowitz, Mark M Ross, Donald F Hunt, Ku-Lung Hsu
Direct Target Site Identification of a Sulfonyl-Triazole Covalent Kinase Probe by LC-MS Chemical Proteomics. Analytical chemistry 93 (35) (2021)
Adam L Borne, Jeffrey W Brulet, Kun Yuan, Ku-Lung Hsu
Development and biological applications of sulfur-triazole exchange (SuTEx) chemistry. RSC chemical biology 2 (2) (2021)
Timothy B Ware, Caroline E Franks, Mitchell E Granade, Mingxing Zhang, Kee-Beom Kim, Kwon-Sik Park, Andreas Gahlmann, Thurl E Harris, Ku-Lung Hsu
Reprogramming fatty acyl specificity of lipid kinases via C1 domain engineering. Nature chemical biology 16 (2) (2020)
Bocheng Yin, Roberto Mendez, Xiao-Yu Zhao, Rishi Rakhit, Ku-Lung Hsu, Sarah E Ewald
Automated Spatially Targeted Optical Microproteomics (autoSTOMP) to Determine Protein Complexity of Subcellular Structures. Analytical chemistry 92 (2) (2020)
Scott M Seki, Kacper Posyniak, Rebecca McCloud, Abagail M Rosen, Anthony Fernández-Castañeda, Rebecca M Beiter, Vlad Serbulea, Sarah C Nanziri, Nikolas W Hayes, Charles Spivey, Lelisa F Gemta, Timothy N J Bullock, Ku-Lung Hsu, Alban Gaultier
Modulation of PKM activity affects the differentiation of TH17 cells. Science signaling 13 (655) (2020)
Jeffrey W Brulet, Adam L Borne, Kun Yuan, Adam H Libby, Ku-Lung Hsu
Liganding Functional Tyrosine Sites on Proteins Using Sulfur-Triazole Exchange Chemistry. Journal of the American Chemical Society 142 (18) (2020)
John S Lazo, Isabella K Blanco, Nikhil R Tasker, Ettore J Rastelli, James C Burnett, Sharon R Garrott, Duncan J Hart, Rebecca L McCloud, Ku-Lung Hsu, Peter Wipf, Elizabeth R Sharlow
Next-Generation Cell-Active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase. The Journal of pharmacology and experimental therapeutics 371 (3) (2019)
Heung Sik Hahm, Emmanuel K Toroitich, Adam L Borne, Jeffrey W Brulet, Adam H Libby, Kun Yuan, Timothy B Ware, Rebecca L McCloud, Anthony M Ciancone, Ku-Lung Hsu
Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. Nature chemical biology 16 (2) (2019)
Myungsun Shin, Caroline E Franks, Ku-Lung Hsu
Isoform-selective activity-based profiling of ERK signaling. Chemical science 9 (9) (2018)
Myungsun Shin, Helena W Snyder, Giulia Donvito, Lesley D Schurman, Todd E Fox, Aron H Lichtman, Mark Kester, Ku-Lung Hsu
Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo. Molecular pharmaceutics 15 (3) (2017)
Rebecca L McCloud, Caroline E Franks, Sean T Campbell, Benjamin W Purow, Thurl E Harris, Ku-Lung Hsu
Deconstructing Lipid Kinase Inhibitors by Chemical Proteomics. Biochemistry 57 (2) (2017)
Matthew W Buczynski, Melissa A Herman, Ku-Lung Hsu, Luis A Natividad, Cristina Irimia, Ilham Y Polis, Holly Pugh, Jae Won Chang, Micah J Niphakis, Benjamin F Cravatt, Marisa Roberto, Loren H Parsons
Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure. Proceedings of the National Academy of Sciences of the United States of America 113 (4) (2016)
Jordon M Inloes, Ku-Lung Hsu, Melissa M Dix, Andreu Viader, Kim Masuda, Thais Takei, Malcolm R Wood, Benjamin F Cravatt
The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase. Proceedings of the National Academy of Sciences of the United States of America 111 (41) (2014)

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Publication Activity (10 Years)

Top Topics

Top Venues

Ku-Lung Hsu