Joseph Clayton

Publication Activity (10 Years)

Years Active: 2022-2024
Publications (10 Years): 24

Top Topics

Density Functional Theory

Machine Learning

Metastatic Colorectal Cancer

Histone Deacetylase

Top Venues

bioRxiv : the preprint server for biology

Journal of chemical information and modeling

This page only lists publications with an associated author ORCID identifier.

Publications

Ruibin Liu, Joseph Clayton, Mingzhe Shen, Shubham Bhatnagar, Jana Shen
Machine Learning Models to Interrogate Proteome-Wide Covalent Ligandabilities Directed at Cysteines. JACS Au 4 (4) (2024)
Ruibin Liu, Joseph Clayton, Mingzhe Shen, Shubham Bhatnagar, Jana Shen
Machine Learning Models to Interrogate Proteome-Wide Covalent Ligandabilities Directed at Cysteines. JACS Au 4 (4) (2024)
Ruibin Liu, Joseph Clayton, Mingzhe Shen, Shubham Bhatnagar, Jana Shen
Machine Learning Models to Interrogate Proteome-Wide Covalent Ligandabilities Directed at Cysteines. JACS Au 4 (4) (2024)
Ruibin Liu, Joseph Clayton, Mingzhe Shen, Shubham Bhatnagar, Jana Shen
Machine Learning Models to Interrogate Proteome-Wide Covalent Ligandabilities Directed at Cysteines. JACS Au 4 (4) (2024)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF Inhibitors. bioRxiv : the preprint server for biology (2024)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF Inhibitors. bioRxiv : the preprint server for biology (2024)
Mohamed Ibrahim, Xinyuanyuan Sun, Vinicius Martins de Oliveira, Ruibin Liu, Joseph Clayton, Haifa El Kilani, Jana Shen, Rolf Hilgenfeld
Why is the Omicron main protease of SARS-CoV-2 less stable than its wild-type counterpart? A crystallographic, biophysical, and theoretical study of the free enzyme and its complex with inhibitor 13b-K. bioRxiv : the preprint server for biology (2024)
Mohamed Ibrahim, Xinyuanyuan Sun, Vinicius Martins de Oliveira, Ruibin Liu, Joseph Clayton, Haifa El Kilani, Jana Shen, Rolf Hilgenfeld
Why is the Omicron main protease of SARS-CoV-2 less stable than its wild-type counterpart? A crystallographic, biophysical, and theoretical study of the free enzyme and its complex with inhibitor 13b-K. bioRxiv : the preprint server for biology (2024)
Ruibin Liu, Joseph Clayton, Mingzhe Shen, Shubham Bhatnagar, Jana Shen
Machine Learning Models to Interrogate Proteome-Wide Covalent Ligandabilities Directed at Cysteines. JACS Au 4 (4) (2024)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF Inhibitors. bioRxiv : the preprint server for biology (2024)
Mohamed Ibrahim, Xinyuanyuan Sun, Vinicius Martins de Oliveira, Ruibin Liu, Joseph Clayton, Haifa El Kilani, Jana Shen, Rolf Hilgenfeld
Why is the Omicron main protease of SARS-CoV-2 less stable than its wild-type counterpart? A crystallographic, biophysical, and theoretical study of the free enzyme and its complex with inhibitor 13b-K. bioRxiv : the preprint server for biology (2024)
Mohamed Ibrahim, Xinyuanyuan Sun, Vinicius Martins de Oliveira, Ruibin Liu, Joseph Clayton, Haifa El Kilani, Jana Shen, Rolf Hilgenfeld
Why is the Omicron main protease of SARS-CoV-2 less stable than its wild-type counterpart? A crystallographic, biophysical, and theoretical study of the free enzyme and its complex with inhibitor 13b-K. bioRxiv : the preprint server for biology (2024)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF Inhibitors. bioRxiv : the preprint server for biology (2024)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF Inhibitors. bioRxiv : the preprint server for biology (2024)
Ruibin Liu, Joseph Clayton, Mingzhe Shen, Shubham Bhatnagar, Jana Shen
Machine Learning Models to Interrogate Proteome-Wide Covalent Ligandabilities Directed at Cysteines. JACS Au 4 (4) (2024)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors. bioRxiv : the preprint server for biology (2023)
Aarion Romany, Ruibin Liu, Shaoqi Zhan, Joseph Clayton, Jana Shen
Analysis of the ERK Pathway Cysteinome for Targeted Covalent Inhibition of RAF and MEK Kinases. Journal of chemical information and modeling (2023)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors. bioRxiv : the preprint server for biology (2023)
Joseph Clayton, Vinicius Martins de Oliveira, Mohamed Fouad Ibrahim, Xinyuanyuan Sun, Paween Mahinthichaichan, Mingzhe Shen, Rolf Hilgenfeld, Jana Shen
Integrative Approach to Dissect the Drug Resistance Mechanism of the H172Y Mutation of SARS-CoV-2 Main Protease. Journal of chemical information and modeling (2023)
Ruibin Liu, Joseph Clayton, Mingzhe Shen, Jana Shen
Interrogating Proteome-wide Cysteine Ligandabilities: Crystallography Meets Chemoproteomics Through Machine Learning. bioRxiv : the preprint server for biology (2023)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors. bioRxiv : the preprint server for biology (2023)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors. bioRxiv : the preprint server for biology (2023)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors. bioRxiv : the preprint server for biology (2023)
Rongze Yang, Shuyan Han, Joseph Clayton, Mahan Haghighatian, Cheng-Chieh Tsai, Yuan Yao, Pingping Li, Jana Shen, Qun Zhou
A Proof-of-Concept Inhibitor of Endothelial Lipase Suppresses Triple-Negative Breast Cancer Cells by Hijacking the Mitochondrial Function. Cancers 14 (15) (2022)