Kara A Bernstein

Pitt ID Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 18

Top Venues

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

PLoS genetics

Genes

University of Pittsburgh School of Medicine

Yale University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Pittsburgh School of Medicine

United States

Associate Professor (with tenure) :: Microbiology and Molecular Genetics

University of Pittsburgh School of Medicine

United States

Assistant Professor :: Microbiology and Molecular Genetics

Columbia University Medical Center

United States

Associate Research Scientist :: Genetics and Development

Columbia University Medical Center

United States

Post-doctorate Scientist :: Genetics and Development

Education History

Yale University

United States

PHD :: Genetics and Development

Publications

Sarah R Hengel, Katherine G Oppenheimer, Chelsea M Smith, Matthew A Schaich, Hayley L Rein, Julieta Martino, Kristie E Darrah, Maggie Witham, Oluchi C Ezekwenna, Kyle R Burton, Bennett Van Houten, Maria Spies, Kara A Bernstein
The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA. Nature communications 15 (1) (2024)
Sarah R Hengel, Katherine G Oppenheimer, Chelsea M Smith, Matthew A Schaich, Hayley L Rein, Julieta Martino, Kristie E Darrah, Maggie Witham, Oluchi C Ezekwenna, Kyle R Burton, Bennett Van Houten, Maria Spies, Kara A Bernstein
The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA. Nature communications 15 (1) (2024)
Sarah R Hengel, Katherine G Oppenheimer, Chelsea M Smith, Matthew A Schaich, Hayley L Rein, Julieta Martino, Kristie E Darrah, Maggie Witham, Oluchi C Ezekwenna, Kyle R Burton, Bennett Van Houten, Maria Spies, Kara A Bernstein
The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA. Nature communications 15 (1) (2024)
Sarah R Hengel, Katherine G Oppenheimer, Chelsea M Smith, Matthew A Schaich, Hayley L Rein, Julieta Martino, Kristie E Darrah, Maggie Witham, Oluchi C Ezekwenna, Kyle R Burton, Bennett Van Houten, Maria Spies, Kara A Bernstein
The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA. Nature communications 15 (1) (2024)
Li Wan, Sabrina Toland, Lindsey R Robinson-McCarthy, Nara Lee, Matthew A Schaich, Sarah R Hengel, Xiaochen Li, Kara A Bernstein, Bennett Van Houten, Yuan Chang, Patrick S Moore
Unlicensed origin DNA melting by MCV and SV40 polyomavirus LT proteins is independent of ATP-dependent helicase activity. Proceedings of the National Academy of Sciences of the United States of America 120 (30) (2023)
Thong T Luong, Zheqi Li, Nolan Priedigkeit, Phoebe S Parker, Stefanie Böhm, Kyle Rapchak, Adrian V Lee, Kara A Bernstein
Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer. PLoS genetics 18 (9) (2022)
Rohit Prakash, Yashpal Rawal, Meghan R Sullivan, McKenzie K Grundy, Hélène Bret, Michael J Mihalevic, Hayley L Rein, Jared M Baird, Kristie Darrah, Fang Zhang, Raymond Wang, Tiffany A Traina, Marc R Radke, Scott H Kaufmann, Elizabeth M Swisher, Raphaël Guérois, Mauro Modesti, Patrick Sung, Maria Jasin, Kara A Bernstein
Homologous recombination-deficient mutation cluster in tumor suppressor RAD51C identified by comprehensive analysis of cancer variants. Proceedings of the National Academy of Sciences of the United States of America 119 (38) (2022)
Shoumei Bai, Sarah E Taylor, Mohd Azrin Jamalruddin, Stacy McGonigal, Edward Grimley, Dongli Yang, Kara A Bernstein, Ronald J Buckanovich
Targeting Therapeutic Resistance and Multinucleate Giant Cells in CCNE1-Amplified HR-Proficient Ovarian Cancer. Molecular cancer therapeutics 21 (9) (2022)
Braulio Bonilla, Alexander J Brown, Sarah R Hengel, Kyle S Rapchak, Debra Mitchell, Catherine A Pressimone, Adeola A Fagunloye, Thong T Luong, Reagan A Russell, Rudri K Vyas, Tony M Mertz, Hani S Zaher, Nima Mosammaparast, Ewa P Malc, Piotr A Mieczkowski, Steven A Roberts, Kara A Bernstein
The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions. eLife 10 (2021)
Rohit Prakash, Thomas Sandoval, Florian Morati, Jennifer A Zagelbaum, Pei Xin Lim, Travis White, Brett Taylor, Raymond Wang, Emilie C B Desclos, Meghan R Sullivan, Hayley L Rein, Kara A Bernstein, Przemek M Krawczyk, Jean Gautier, Mauro Modesti, Fabio Vanoli, Maria Jasin
Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex. Nature communications 12 (1) (2021)
Thong T Luong, Kara A Bernstein
Role and Regulation of the RECQL4 Family during Genomic Integrity Maintenance. Genes 12 (12) (2021)
Meghan R Sullivan, Rohit Prakash, Yashpal Rawal, Weibin Wang, Patrick Sung, Marc R Radke, Scott H Kaufmann, Elizabeth M Swisher, Kara A Bernstein, Maria Jasin
Long-term survival of an ovarian cancer patient harboring a RAD51C missense mutation. Cold Spring Harbor molecular case studies 7 (2) (2021)
Jen-Wei Huang, Ananya Acharya, Angelo Taglialatela, Tarun S Nambiar, Raquel Cuella-Martin, Giuseppe Leuzzi, Samuel B Hayward, Sarah A Joseph, Gregory J Brunette, Roopesh Anand, Rajesh K Soni, Nathan L Clark, Kara A Bernstein, Petr Cejka, Alberto Ciccia
MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage. Nature communications 11 (1) (2020)
McKenzie K Grundy, Ronald J Buckanovich, Kara A Bernstein
Regulation and pharmacological targeting of RAD51 in cancer. NAR cancer 2 (3) (2020)
Edwige B Garcin, Stéphanie Gon, Meghan R Sullivan, Gregory J Brunette, Anne De Cian, Jean-Paul Concordet, Carine Giovannangeli, Wilhelm G Dirks, Sonja Eberth, Kara A Bernstein, Rohit Prakash, Maria Jasin, Mauro Modesti
Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells. PLoS genetics 15 (10) (2019)
Joel C Rosenbaum, Braulio Bonilla, Sarah R Hengel, Tony M Mertz, Benjamin W Herken, Hinke G Kazemier, Catherine A Pressimone, Timothy C Ratterman, Ellen MacNary, Alessio De Magis, Youngho Kwon, Stephen K Godin, Bennett Van Houten, Daniel P Normolle, Patrick Sung, Subha R Das, Katrin Paeschke, Steven A Roberts, Andrew P VanDemark, Kara A Bernstein
The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway. Nature communications 10 (1) (2019)
Meghan R Sullivan, Kara A Bernstein
RAD-ical New Insights into RAD51 Regulation. Genes 9 (12) (2018)
Lucía F Zacchi, John C Dittmar, Michael J Mihalevic, Annette M Shewan, Benjamin L Schulz, Jeffrey L Brodsky, Kara A Bernstein
Early-onset torsion dystonia: a novel high-throughput yeast genetic screen for factors modifying protein levels of torsinAΔE. Disease models & mechanisms 10 (9) (2017)

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Publication Activity (10 Years)

Top Topics

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Kara A Bernstein