Karine Auclair

ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 20

Top Venues

Chembiochem : a European journal of chemical biology

ChemSusChem

Bioconjugate chemistry

ChemMedChem

McGill University

University of Alberta (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

McGill University May 01 2016

Canada

Full Professor :: Chemistry

McGill University May 01 2009 - May 01 2016

Canada

Associate Professor with Tenure :: Chemistry

McGill University Sep 01 2002 - Feb 01 2014

Canada

Associate Member :: Biochemistry

Boehringer Ingelheim Canada Ltd Research and Development Mar 01 2010 - Jul 31 2010

Canada

Visiting Scientist :: Medicinal Chemistry

McGill University Jan 01 2002 - May 01 2009

Canada

Assistant Professor :: Chemistry

University of California, San Francisco Nov 01 1999 - Dec 20 2001

United States

Post-Doctoral Fellow :: Pharmaceutical Chemistry

Education History

University of Alberta Sep 01 1994 - Sep 30 1999

Canada

PHD :: Chemistry

Universite du Quebec a Chicoutimi Sep 01 1991 - May 01 1994

Canada

BSC :: Chemistry

Publications

Chunling Blue Lan, Karine Auclair
1,5,7-Triazabicyclo[4.4.0]dec-5-ene: An Effective Catalyst for Amide Formation by Lactone Aminolysis. The Journal of organic chemistry (2023)
Tayla J Van Oers, Alexia Piercey, Alexandr Belovodskiy, Béla Reiz, Bethan L Donnelly, Wayne Vuong, Mary Joanne Lemieux, James A Nieman, Karine Auclair, John C Vederas
Deuteration for Metabolic Stabilization of SARS-CoV-2 Inhibitors GC373 and Nirmatrelvir. Organic letters (2023)
Jane Arciszewski, Karine Auclair
Mechanoenzymatic Reactions Involving Polymeric Substrates or Products. ChemSusChem 15 (7) (2022)
Sandra Kaabel, Jane Arciszewski, Tristan H Borchers, J P Daniel Therien, Tomislav Friščić, Karine Auclair
Solid-State Enzymatic Hydrolysis of Mixed PET/Cotton Textiles. ChemSusChem (2022)
Julie Ducharme, Irina F Sevrioukova, Christopher J Thibodeaux, Karine Auclair
Structural Dynamics of Cytochrome P450 3A4 in the Presence of Substrates and Cytochrome P450 Reductase. Biochemistry 60 (28) (2021)
Jinming Guan, Christina Spry, Erick T Tjhin, Penghui Yang, Tanakorn Kittikool, Vanessa M Howieson, Harriet Ling, Lora Starrs, Dustin Duncan, Gaetan Burgio, Kevin J Saliba, Karine Auclair
Exploring Heteroaromatic Rings as a Replacement for the Labile Amide of Antiplasmodial Pantothenamides. Journal of medicinal chemistry 64 (8) (2021)
Sandra Kaabel, J P Daniel Therien, Catherine E Deschênes, Dustin Duncan, Tomislav Friščić, Karine Auclair
Enzymatic depolymerization of highly crystalline polyethylene terephthalate enabled in moist-solid reaction mixtures. Proceedings of the National Academy of Sciences of the United States of America 118 (29) (2021)
Julie Ducharme, Vanja Polic, Christopher J Thibodeaux, Karine Auclair
Combining Small-Molecule Bioconjugation and Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) to Expose Allostery: the Case of Human Cytochrome P450 3A4. ACS chemical biology 16 (5) (2021)
Fabien Hammerer, Shaghayegh Ostadjoo, Tomislav Friščić, Karine Auclair
Towards Controlling the Reactivity of Enzymes in Mechanochemistry: Inert Surfaces Protect β-Glucosidase Activity During Ball Milling. ChemSusChem 13 (1) (2019)
Yun Wang, Jinming Guan, Justin M Di Trani, Karine Auclair, Anthony K Mittermaier
Inhibition and Activation of Kinases by Reaction Products: A Reporter-Free Assay. Analytical chemistry 91 (18) (2019)
Sandra Kaabel, Tomislav Friščić, Karine Auclair
Mechanoenzymatic Transformations in the Absence of Bulk Water: A More Natural Way of Using Enzymes. Chembiochem : a European journal of chemical biology 21 (6) (2019)
Julie Ducharme, Vanja Polic, Karine Auclair
A Covalently Attached Progesterone Molecule Outcompetes the Binding of Free Progesterone at an Allosteric Site of Cytochrome P450 3A4. Bioconjugate chemistry 30 (6) (2019)
J P Daniel Therien, Fabien Hammerer, Tomislav Friščić, Karine Auclair
Mechanoenzymatic Breakdown of Chitinous Material to N-Acetylglucosamine: The Benefits of a Solventless Environment. ChemSusChem 12 (15) (2019)
Fabien Hammerer, Leigh Loots, Jean-Louis Do, J P Daniel Therien, Christopher W Nickels, Tomislav Friščić, Karine Auclair
Solvent-Free Enzyme Activity: Quick, High-Yielding Mechanoenzymatic Hydrolysis of Cellulose into Glucose. Angewandte Chemie (International ed. in English) 57 (10) (2018)
Jinming Guan, Erick T Tjhin, Vanessa M Howieson, Tanakorn Kittikool, Christina Spry, Kevin J Saliba, Karine Auclair
Structure-Activity Relationships of Antiplasmodial Pantothenamide Analogues Reveal a New Way by Which Triazoles Mimic Amide Bonds. ChemMedChem 13 (24) (2018)
Jinming Guan, Kenward Vong, Kathleen Wee, Johans Fakhoury, Edie Dullaghan, Karine Auclair
Cellular Studies of an Aminoglycoside Potentiator Reveal a New Inhibitor of Aminoglycoside Resistance. Chembiochem : a European journal of chemical biology 19 (19) (2018)
Erick T Tjhin, Christina Spry, Alan L Sewell, Annabelle Hoegl, Leanne Barnard, Anna E Sexton, Ghizal Siddiqui, Vanessa M Howieson, Alexander G Maier, Darren John Creek, Erick Strauss, Rodolfo Marquez, Karine Auclair, Kevin J Saliba
Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues. PLoS pathogens 14 (4) (2018)
Julie Ducharme, Karine Auclair
Enzymes Beat Chemists in the Formation of an Unnatural Bond. Chembiochem : a European journal of chemical biology 18 (5) (2017)
Vanja Polic, Karine Auclair
Allosteric Activation of Cytochrome P450 3A4 via Progesterone Bioconjugation. Bioconjugate chemistry 28 (4) (2017)
Paolo Schiavini, Kin J Cheong, Nicolas Moitessier, Karine Auclair
Active Site Crowding of Cytochrome P450 3A4 as a Strategy To Alter Its Selectivity. Chembiochem : a European journal of chemical biology 18 (3) (2016)

Karine Auclair.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Karine Auclair