Keary M Engle

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 63

Top Venues

Angewandte Chemie (International ed. in English)

Journal of the American Chemical Society

Chemical science

Organic letters

Scripps Research Institute

Scripps Research Institute (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Scripps Research Institute Jun 01 2015

United States

Assistant Professor :: Department of Chemistry

California Institute of Technology - Jun 01 2015

United States

NIH Postdoctoral Fellow :: Division of Chemistry and Chemical Engineering

Education History

Scripps Research Institute Aug 01 2008 - May 28 2013

United States

PHD :: Department of Chemistry

University of Michigan

United States

BSC

Publications

Hui-Qi Ni, Turki M Alturaifi, Warabhorn Rodphon, Nicholas F Scherschel, Shouliang Yang, Fen Wang, Indrawan J McAlpine, Davin G Piercey, Peng Liu, Keary M Engle
Anti -selective Cyclopropanation of Nonconjugated Alkenes with Diverse Pronucleophiles via Directed Nucleopalladation. Journal of the American Chemical Society (2024)
Gabriele Laudadio, Philipp Neigenfind, Áron Péter, Camille Z Rubel, Megan A Emmanuel, Martins S Oderinde, Tamara El-Hayek Ewing, Maximilian D Palkowitz, Jack L Sloane, Kevin W Gillman, Daniel Ridge, Michael D Mandler, Philippe N Bolduc, Michael C Nicastri, Benxiang Zhang, Sebastian Clementson, Nadia Nasser Petersen, Pablo Martín-Gago, Pavel Mykhailiuk, Keary M Engle, Phil S Baran
Nickel-Electrocatalytic Decarboxylative Arylation to Access Quaternary Centers. Angewandte Chemie (International ed. in English) 63 (8) (2024)
Hui Zhao, Anne K Ravn, Michael C Haibach, Keary M Engle, Carin C C Johansson Seechurn
Diversification of Pharmaceutical Manufacturing Processes: Taking the Plunge into the Non-PGM Catalyst Pool. ACS catalysis 14 (13) (2024)
Camille Z Rubel, Wen-Ji He, Steven R Wisniewski, Keary M Engle
Benchtop Nickel Catalysis Invigorated by Electron-Deficient Diene Ligands. Accounts of chemical research 57 (3) (2024)
Hui Zhao, Anne K Ravn, Michael C Haibach, Keary M Engle, Carin C C Johansson Seechurn
Diversification of Pharmaceutical Manufacturing Processes: Taking the Plunge into the Non-PGM Catalyst Pool. ACS catalysis 14 (13) (2024)
Gabriele Laudadio, Philipp Neigenfind, Áron Péter, Camille Z Rubel, Megan A Emmanuel, Martins S Oderinde, Tamara El-Hayek Ewing, Maximilian D Palkowitz, Jack L Sloane, Kevin W Gillman, Daniel Ridge, Michael D Mandler, Philippe N Bolduc, Michael C Nicastri, Benxiang Zhang, Sebastian Clementson, Nadia Nasser Petersen, Pablo Martín-Gago, Pavel Mykhailiuk, Keary M Engle, Phil S Baran
Nickel-Electrocatalytic Decarboxylative Arylation to Access Quaternary Centers. Angewandte Chemie (International ed. in English) 63 (8) (2024)
Camille Z Rubel, Anne K Ravn, Hang Chi Ho, Shenghua Yang, Zi-Qi Li, Keary M Engle, Julien C Vantourout
Stereodivergent, Kinetically Controlled Isomerization of Terminal Alkenes via Nickel Catalysis. Angewandte Chemie (International ed. in English) (2024)
Gabriele Laudadio, Philipp Neigenfind, Áron Péter, Camille Z Rubel, Megan A Emmanuel, Martins S Oderinde, Tamara El-Hayek Ewing, Maximilian D Palkowitz, Jack L Sloane, Kevin W Gillman, Daniel Ridge, Michael D Mandler, Philippe N Bolduc, Michael C Nicastri, Benxiang Zhang, Sebastian Clementson, Nadia Nasser Petersen, Pablo Martín-Gago, Pavel Mykhailiuk, Keary M Engle, Phil S Baran
Nickel-Electrocatalytic Decarboxylative Arylation to Access Quaternary Centers. Angewandte Chemie (International ed. in English) (2024)
Camille Z Rubel, Anne K Ravn, Hang Chi Ho, Shenghua Yang, Zi-Qi Li, Keary M Engle, Julien C Vantourout
Stereodivergent, Kinetically Controlled Isomerization of Terminal Alkenes via Nickel Catalysis. Angewandte Chemie (International ed. in English) 63 (21) (2024)
Camille Z Rubel, Wen-Ji He, Steven R Wisniewski, Keary M Engle
Benchtop Nickel Catalysis Invigorated by Electron-Deficient Diene Ligands. Accounts of chemical research (2024)
Van T Tran, Nana Kim, Camille Z Rubel, Xiangyu Wu, Taeho Kang, Tanner C Jankins, Zi-Qi Li, Matthew V Joannou, Sloan Ayers, Milan Gembický, Jake B Bailey, Emily J Sturgell, Brittany B Sanchez, Jason S Chen, Song Lin, Martin D Eastgate, Steven R Wisniewski, Keary M Engle
Structurally Diverse Bench-Stable Nickel(0) Pre-Catalysts: A Practical Toolkit for In Situ Ligation Protocols. Angewandte Chemie (International ed. in English) 62 (9) (2023)
Yeongyu Hwang, Steven R Wisniewski, Keary M Engle
Ligand-Enabled Carboamidation of Unactivated Alkenes through Enhanced Organonickel Electrophilicity. Journal of the American Chemical Society (2023)
Tao Zhang, Kangbao Zhong, Zhi-Keng Lin, Linbin Niu, Zi-Qi Li, Ruopeng Bai, Keary M Engle, Yu Lan
Revised Mechanism of C(sp 3 )-C(sp 3 ) Reductive Elimination from Ni(II) with the Assistance of a Z-Type Metalloligand. Journal of the American Chemical Society 145 (4) (2023)
Van T Tran, Nana Kim, Camille Z Rubel, Xiangyu Wu, Taeho Kang, Tanner C Jankins, Zi-Qi Li, Matthew V Joannou, Sloan Ayers, Milan Gembický, Jake B Bailey, Emily J Sturgell, Brittany B Sanchez, Jason S Chen, Song Lin, Martin D Eastgate, Steven R Wisniewski, Keary M Engle
Structurally Diverse Bench-Stable Nickel(0) Pre-Catalysts: A Practical Toolkit for In Situ Ligation Protocols. Angewandte Chemie (International ed. in English) 62 (9) (2023)
Van T Tran, Nana Kim, Camille Z Rubel, Xiangyu Wu, Taeho Kang, Tanner C Jankins, Zi-Qi Li, Matthew V Joannou, Sloan Ayers, Milan Gembický, Jake B Bailey, Emily J Sturgell, Brittany B Sanchez, Jason S Chen, Song Lin, Martin D Eastgate, Steven R Wisniewski, Keary M Engle
Structurally Diverse Bench-Stable Nickel(0) Pre-Catalysts: A Practical Toolkit for In Situ Ligation Protocols. Angewandte Chemie (International ed. in English) 62 (9) (2023)
Hui-Qi Ni, Malkanthi K Karunananda, Tian Zeng, Shenghua Yang, Zhen Liu, Kendall N Houk, Peng Liu, Keary M Engle
Redox-Paired Alkene Difunctionalization Enables Skeletally Divergent Synthesis. Journal of the American Chemical Society (2023)
Tao Zhang, Kangbao Zhong, Zhi-Keng Lin, Linbin Niu, Zi-Qi Li, Ruopeng Bai, Keary M Engle, Yu Lan
Revised Mechanism of C(sp 3 )-C(sp 3 ) Reductive Elimination from Ni(II) with the Assistance of a Z-Type Metalloligand. Journal of the American Chemical Society (2023)
Van T Tran, Nana Kim, Camille Z Rubel, Xiangyu Wu, Taeho Kang, Tanner C Jankins, Zi-Qi Li, Matthew V Joannou, Sloan Ayers, Milan Gembický, Jake B Bailey, Emily J Sturgell, Brittany B Sanchez, Jason S Chen, Song Lin, Martin D Eastgate, Steven R Wisniewski, Keary M Engle
Structurally Diverse Bench-Stable Nickel(0) Pre-Catalysts: A Practical Toolkit for In Situ Ligation Protocols. Angewandte Chemie (International ed. in English) (2022)
Mingyu Liu, Juntao Sun, Tao Zhang, Yi Ding, Ye-Qiang Han, Raúl Martín-Montero, Yu Lan, Timothy M Swager, Keary M Engle
Regio- and Stereoselective 1,2-Oxyhalogenation of Non-Conjugated Alkynes via Directed Nucleopalladation: Catalytic Access to Tetrasubstituted Alkenes. Angewandte Chemie (International ed. in English) 61 (43) (2022)
Mingyu Liu, Juntao Sun, Tuğçe G Erbay, Hui-Qi Ni, Raúl Martín-Montero, Peng Liu, Keary M Engle
Pd II -Catalyzed C(alkenyl)-H Activation Facilitated by a Transient Directing Group. Angewandte Chemie (International ed. in English) 61 (25) (2022)
Omar Apolinar, Taeho Kang, Turki M Alturaifi, Pranali G Bedekar, Camille Z Rubel, Joseph Derosa, Brittany B Sanchez, Quynh Nguyen Wong, Emily J Sturgell, Jason S Chen, Steven R Wisniewski, Peng Liu, Keary M Engle
Three-Component Asymmetric Ni-Catalyzed 1,2-Dicarbofunctionalization of Unactivated Alkenes via Stereoselective Migratory Insertion. Journal of the American Chemical Society 144 (42) (2022)
Hui-Qi Ni, Phillippa Cooper, Shouliang Yang, Fen Wang, Neal W Sach, Pranali G Bedekar, Joyann S Donaldson, Michelle Tran-Dubé, Indrawan J McAlpine, Keary M Engle
Mapping Ambiphile Reactivity Trends in the Anti-(Hetero)annulation of Non-Conjugated Alkenes via Pd II /Pd IV Catalysis. Angewandte Chemie (International ed. in English) 61 (13) (2022)
Zi-Qi Li, Yilin Cao, Taeho Kang, Keary M Engle
Electrophilic Sulfur Reagent Design Enables Directed syn -Carbosulfenylation of Unactivated Alkenes. Journal of the American Chemical Society 144 (16) (2022)
Zi-Qi Li, Wen-Ji He, Hui-Qi Ni, Keary M Engle
Directed, nickel-catalyzed 1,2-alkylsulfenylation of alkenyl carbonyl compounds. Chemical science 13 (22) (2022)
Tanner C Jankins, William C Bell, Yu Zhang, Zi-Yang Qin, Jason S Chen, Milan Gembický, Peng Liu, Keary M Engle
Low-valent tungsten redox catalysis enables controlled isomerization and carbonylative functionalization of alkenes. Nature chemistry 14 (6) (2022)
Van T Tran, Nana Kim, Camille Z Rubel, Xiangyu Wu, Taeho Kang, Tanner C Jankins, Zi-Qi Li, Matthew V Joannou, Sloan Ayers, Milan Gembický, Jake B Bailey, Emily J Sturgell, Brittany B Sanchez, Jason S Chen, Song Lin, Martin D Eastgate, Steven R Wisniewski, Keary M Engle
Structurally Diverse Bench-Stable Nickel(0) Pre-Catalysts: A Practical Toolkit for In Situ Ligation Protocols. Angewandte Chemie (International ed. in English) (2022)
Rei Matsuura, Malkanthi K Karunananda, Mingyu Liu, Nhi Nguyen, Donna G Blackmond, Keary M Engle
Mechanistic Studies of Pd(II)-Catalyzed E/Z Isomerization of Unactivated Alkenes: Evidence for a Monometallic Nucleopalladation Pathway. ACS catalysis 11 (7) (2021)
Zi-Qi Li, Omar Apolinar, Ruohan Deng, Keary M Engle
Directed Markovnikov hydroarylation and hydroalkenylation of alkenes under nickel catalysis. Chemical science 12 (33) (2021)
Roman Kleinmans, Omar Apolinar, Joseph Derosa, Malkanthi K Karunananda, Zi-Qi Li, Van T Tran, Steven R Wisniewski, Keary M Engle
Ni-Catalyzed 1,2-Diarylation of Alkenyl Ketones: A Comparative Study of Carbonyl-Directed Reaction Systems. Organic letters 23 (14) (2021)
Tanner C Jankins, Raul Martin-Montero, Phillippa Cooper, Rúben Martín, Keary M Engle
Low-Valent Tungsten Catalysis Enables Site-Selective Isomerization-Hydroboration of Unactivated Alkenes. Journal of the American Chemical Society 143 (37) (2021)
Yang Gao, Sima Yazdani, Aaron Kendrick, Glen P Junor, Taeho Kang, Douglas B Grotjahn, Guy Bertrand, Rodolphe Jazzar, Keary M Engle
Cyclic (Alkyl)(amino)carbene Ligands Enable Cu-Catalyzed Markovnikov Protoboration and Protosilylation of Terminal Alkynes: A Versatile Portal to Functionalized Alkenes*. Angewandte Chemie (International ed. in English) 60 (36) (2021)
Mingyu Liu, Tianhua Tang, Omar Apolinar, Rei Matsuura, Carl A Busacca, Bo Qu, Daniel R Fandrick, Olga V Zatolochnaya, Chris H Senanayake, Jinhua J Song, Keary M Engle
Atom-Economical Cross-Coupling of Internal and Terminal Alkynes to Access 1,3-Enynes. Journal of the American Chemical Society 143 (10) (2021)
Hui-Qi Ni, Phillippa Cooper, Keary M Engle
Recent advances in palladium-catalyzed (hetero)annulation of C[double bond, length as m-dash]C bonds with ambiphilic organo(pseudo)halides. Chemical communications (Cambridge, England) 57 (62) (2021)
Bin Liu, Andrew M Romine, Camille Z Rubel, Keary M Engle, Timothy M Swager
Transition-Metal-Catalyzed, Coordination-Assisted Functionalization of Nonactivated C(sp3)-H Bonds. Chemical reviews (2021)
Taeho Kang, Nana Kim, Peter T W Cheng, Hao Zhang, Klement Foo, Keary M Engle
Nickel-Catalyzed 1,2-Carboamination of Alkenyl Alcohols. Journal of the American Chemical Society 143 (34) (2021)
Zhonglin Liu, Lucas J Oxtoby, Mingyu Liu, Zi-Qi Li, Van T Tran, Yang Gao, Keary M Engle
A Transient Directing Group Strategy Enables Enantioselective Multicomponent Organofluorine Synthesis. Journal of the American Chemical Society 143 (24) (2021)
Hui-Qi Ni, Ilia Kevlishvili, Pranali G Bedekar, Joyann S Barber, Shouliang Yang, Michelle Tran-Dubé, Andrew M Romine, Hou-Xiang Lu, Indrawan J McAlpine, Peng Liu, Keary M Engle
Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation. Nature communications 11 (1) (2020)
Alena M Vasquez, John A Gurak, Candice L Joe, Emily C Cherney, Keary M Engle
Catalytic α-Hydroarylation of Acrylates and Acrylamides via an Interrupted Hydrodehalogenation Reaction. Journal of the American Chemical Society 142 (23) (2020)
Van T Tran, Zi-Qi Li, Omar Apolinar, Joseph Derosa, Matthew V Joannou, Steven R Wisniewski, Martin D Eastgate, Keary M Engle
Ni(COD)(DQ): An Air-Stable 18-Electron Nickel(0)-Olefin Precatalyst. Angewandte Chemie (International ed. in English) 59 (19) (2020)
Lucas J Oxtoby, Zi-Qi Li, Van T Tran, Tuğçe G Erbay, Ruohan Deng, Peng Liu, Keary M Engle
A Transient-Directing-Group Strategy Enables Enantioselective Reductive Heck Hydroarylation of Alkenes. Angewandte Chemie (International ed. in English) 59 (23) (2020)
Van T Tran, Zi-Qi Li, Timothy J Gallagher, Joseph Derosa, Peng Liu, Keary M Engle
Integrating Allyl Electrophiles into Nickel-Catalyzed Conjunctive Cross-Coupling. Angewandte Chemie (International ed. in English) 59 (18) (2020)
Xin Wang, Zi-Qi Li, Binh Khanh Mai, John A Gurak, Jessica E Xu, Van T Tran, Hui-Qi Ni, Zhen Liu, Zhonglin Liu, Kin S Yang, Rong Xiang, Peng Liu, Keary M Engle
Controlling cyclization pathways in palladium(ii)-catalyzed intramolecular alkene hydro-functionalization via substrate directivity. Chemical science 11 (41) (2020)
Zi-Qi Li, Yue Fu, Ruohan Deng, Van T Tran, Yang Gao, Peng Liu, Keary M Engle
Ligand-Controlled Regiodivergence in Nickel-Catalyzed Hydroarylation and Hydroalkenylation of Alkenyl Carboxylic Acids*. Angewandte Chemie (International ed. in English) 59 (51) (2020)
Joseph Derosa, Omar Apolinar, Taeho Kang, Van T Tran, Keary M Engle
Recent developments in nickel-catalyzed intermolecular dicarbofunctionalization of alkenes. Chemical science 11 (17) (2020)
Yang Gao, Zhong-Qian Wu, Keary M Engle
Synthesis of Stereodefined 1,1-Diborylalkenes via Copper-Catalyzed Diboration of Terminal Alkynes. Organic letters 22 (13) (2020)
Van T Tran, Sri Krishna Nimmagadda, Mingyu Liu, Keary M Engle
Recent applications of chiral phosphoric acids in palladium catalysis. Organic & biomolecular chemistry 18 (4) (2020)
Sri Krishna Nimmagadda, Mingyu Liu, Malkanthi K Karunananda, De-Wei Gao, Omar Apolinar, Jason S Chen, Peng Liu, Keary M Engle
Catalytic, Enantioselective α-Alkylation of Azlactones with Nonconjugated Alkenes by Directed Nucleopalladation. Angewandte Chemie (International ed. in English) 58 (12) (2019)
Joseph Derosa, Taeho Kang, Van T Tran, Steven R Wisniewski, Malkanthi K Karunananda, Tanner C Jankins, Kane L Xu, Keary M Engle
Nickel-Catalyzed 1,2-Diarylation of Alkenyl Carboxylates: A Gateway to 1,2,3-Trifunctionalized Building Blocks. Angewandte Chemie (International ed. in English) 59 (3) (2019)
Honggui Lv, Huiying Kang, Biying Zhou, Xiao-Song Xue, Keary M Engle, Dongbing Zhao
Nickel-catalyzed intermolecular oxidative Heck arylation driven by transfer hydrogenation. Nature communications 10 (1) (2019)
Zhen Liu, Jiahao Chen, Hou-Xiang Lu, Xiaohan Li, Yang Gao, John R Coombs, Matthew J Goldfogel, Keary M Engle
Palladium(0)-Catalyzed Directed syn-1,2-Carboboration and -Silylation: Alkene Scope, Applications in Dearomatization, and Stereocontrol by a Chiral Auxiliary. Angewandte Chemie (International ed. in English) 58 (47) (2019)
Joseph Derosa, Vincent A van der Puyl, Van T Tran, Mingyu Liu, Keary M Engle
Directed nickel-catalyzed 1,2-dialkylation of alkenyl carbonyl compounds. Chemical science 9 (23) (2018)
Van T Tran, John A Gurak, Kin S Yang, Keary M Engle
Activation of diverse carbon-heteroatom and carbon-carbon bonds via palladium(II)-catalysed β-X elimination. Nature chemistry 10 (11) (2018)
Tian Zeng, Zhen Liu, Michael A Schmidt, Martin D Eastgate, Keary M Engle
Directed, Palladium(II)-Catalyzed Intermolecular Aminohydroxylation of Alkenes Using a Mild Oxidation System. Organic letters 20 (13) (2018)
Mingyu Liu, Pusu Yang, Malkanthi K Karunananda, Yanyan Wang, Peng Liu, Keary M Engle
C(alkenyl)-H Activation via Six-Membered Palladacycles: Catalytic 1,3-Diene Synthesis. Journal of the American Chemical Society 140 (17) (2018)
Joseph Derosa, Miriam L O'Duill, Matthew Holcomb, Mark N Boulous, Ryan L Patman, Fen Wang, Michelle Tran-Dubé, Indrawan McAlpine, Keary M Engle
Copper-Catalyzed Chan-Lam Cyclopropylation of Phenols and Azaheterocycles. The Journal of organic chemistry 83 (7) (2018)
Rei Matsuura, Tanner C Jankins, David E Hill, Kin S Yang, Gary M Gallego, Shouliang Yang, Mingying He, Fen Wang, Rohan P Marsters, Indrawan McAlpine, Keary M Engle
Palladium(ii)-catalyzed γ-selective hydroarylation of alkenyl carbonyl compounds with arylboronic acids. Chemical science 9 (44) (2018)
Zhen Liu, Hui-Qi Ni, Tian Zeng, Keary M Engle
Catalytic Carbo- and Aminoboration of Alkenyl Carbonyl Compounds via Five- and Six-Membered Palladacycles. Journal of the American Chemical Society 140 (9) (2018)
Joseph Derosa, Roman Kleinmans, Van T Tran, Malkanthi K Karunananda, Steven R Wisniewski, Martin D Eastgate, Keary M Engle
Nickel-Catalyzed 1,2-Diarylation of Simple Alkenyl Amides. Journal of the American Chemical Society 140 (51) (2018)
De-Wei Gao, Ekaterina V Vinogradova, Sri Krishna Nimmagadda, Jose M Medina, Yiyang Xiao, Radu M Suciu, Benjamin F Cravatt, Keary M Engle
Direct Access to Versatile Electrophiles via Catalytic Oxidative Cyanation of Alkenes. Journal of the American Chemical Society 140 (26) (2018)
Miriam L O'Duill, Rei Matsuura, Yanyan Wang, Joshua L Turnbull, John A Gurak, De-Wei Gao, Gang Lu, Peng Liu, Keary M Engle
Tridentate Directing Groups Stabilize 6-Membered Palladacycles in Catalytic Alkene Hydrofunctionalization. Journal of the American Chemical Society 139 (44) (2017)
Joseph Derosa, Van T Tran, Mark N Boulous, Jason S Chen, Keary M Engle
Nickel-Catalyzed β,γ-Dicarbofunctionalization of Alkenyl Carbonyl Compounds via Conjunctive Cross-Coupling. Journal of the American Chemical Society 139 (31) (2017)
Zhen Liu, Yanyan Wang, Zichen Wang, Tian Zeng, Peng Liu, Keary M Engle
Catalytic Intermolecular Carboamination of Unactivated Alkenes via Directed Aminopalladation. Journal of the American Chemical Society 139 (32) (2017)
Joseph Derosa, Annabelle L Cantu, Mark N Boulous, Miriam L O'Duill, Joshua L Turnbull, Zhen Liu, Daizy M De La Torre, Keary M Engle
Palladium(II)-Catalyzed Directed anti-Hydrochlorination of Unactivated Alkynes with HCl. Journal of the American Chemical Society 139 (14) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Keary M Engle