Kevin R Lynch (K R Lynch)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 15

Top Venues

Journal of medicinal chemistry

bioRxiv : the preprint server for biology

PloS one

Science translational medicine

University of Virginia

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Virginia

United States

Professor :: Pharmacology

Publications

Yugesh Kharel, T Huang, K Dunnavant, D Foster, George M P R Souza, K E Nimchuk, A R Merchak, Caitlin M Pavelec, Z J Juskiewicz, Alban Gaultier, Stephen B G Abbott, Jung-Bum Shin, Brant E Isakson, W Xu, Norbert Leitinger, Webster L Santos, Kevin R Lynch
Assessing Spns2-dependent S1P Transport as a Prospective Therapeutic Target. bioRxiv : the preprint server for biology (2024)
Yugesh Kharel, T Huang, K Dunnavant, D Foster, George M P R Souza, K E Nimchuk, A R Merchak, Caitlin M Pavelec, Z J Juskiewicz, Alban Gaultier, Stephen B G Abbott, Jung-Bum Shin, Brant E Isakson, W Xu, Norbert Leitinger, Webster L Santos, Kevin R Lynch
Assessing Spns2-dependent S1P Transport as a Prospective Therapeutic Target. bioRxiv : the preprint server for biology (2024)
Daniel J Foster, Kyle Dunnavant, Christopher W Shrader, Marion LoPresti, Sarah Seay, Yugesh Kharel, Anne M Brown, Tao Huang, Kevin R Lynch, Webster L Santos
Discovery of Potent, Orally Bioavailable Sphingosine-1-Phosphate Transporter (Spns2) Inhibitors. Journal of medicinal chemistry (2024)
Daniel J Foster, Kyle Dunnavant, Christopher W Shrader, Marion LoPresti, Sarah Seay, Yugesh Kharel, Anne M Brown, Tao Huang, Kevin R Lynch, Webster L Santos
Discovery of Potent, Orally Bioavailable Sphingosine-1-Phosphate Transporter (Spns2) Inhibitors. Journal of medicinal chemistry 67 (13) (2024)
Yugesh Kharel, T Huang, K Dunnavant, D Foster, George M P R Souza, K E Nimchuk, A R Merchak, Caitlin M Pavelec, Z J Juskiewicz, Alban Gaultier, Stephen B G Abbott, Jung-Bum Shin, Brant E Isakson, W Xu, Norbert Leitinger, Webster L Santos, Kevin R Lynch
Assessing Spns2-dependent S1P Transport as a Prospective Therapeutic Target. bioRxiv : the preprint server for biology (2024)
Daniel J Foster, Kyle Dunnavant, Christopher W Shrader, Marion LoPresti, Sarah Seay, Yugesh Kharel, Anne M Brown, Tao Huang, Kevin R Lynch, Webster L Santos
Discovery of Potent, Orally Bioavailable Sphingosine-1-Phosphate Transporter (Spns2) Inhibitors. Journal of medicinal chemistry 67 (13) (2024)
Daniel J Foster, Kyle Dunnavant, Christopher W Shrader, Marion LoPresti, Sarah Seay, Yugesh Kharel, Anne M Brown, Tao Huang, Kevin R Lynch, Webster L Santos
Discovery of Potent, Orally Bioavailable Sphingosine-1-Phosphate Transporter (Spns2) Inhibitors. Journal of medicinal chemistry 67 (13) (2024)
Daniel J Foster, Kyle Dunnavant, Christopher W Shrader, Marion LoPresti, Sarah Seay, Yugesh Kharel, Anne M Brown, Tao Huang, Kevin R Lynch, Webster L Santos
Discovery of Potent, Orally Bioavailable Sphingosine-1-Phosphate Transporter (Spns2) Inhibitors. Journal of medicinal chemistry 67 (13) (2024)
Ariel L Burgio, Christopher W Shrader, Yugesh Kharel, Tao Huang, Joseph M Salamoun, Kevin R Lynch, Webster L Santos
2-Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2). Journal of medicinal chemistry (2023)
Gregory W Busey, Mohan C Manjegowda, Tao Huang, Wesley H Iobst, Shardul S Naphade, Joel A Kennedy, Catherine A Doyle, Philip V Seegren, Kevin R Lynch, Bimal N Desai
Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects. The Journal of general physiology 156 (1) (2023)
Russell Fritzemeier, Daniel Foster, Ashley Peralta, Michael Payette, Yugesh Kharel, Tao Huang, Kevin R Lynch, Webster L Santos
Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors. Journal of medicinal chemistry 65 (11) (2022)
Shinji Tanaka, Shuqiu Zheng, Yugesh Kharel, Russell G Fritzemeier, Tao Huang, Daniel Foster, Nabin Poudel, Eibhlin Goggins, Yusuke Yamaoka, Kinga P Rudnicka, Jonathan E Lipsey, Hope V Radel, Sophia M Ryuh, Tsuyoshi Inoue, Junlan Yao, Diane L Rosin, Susan R Schwab, Webster L Santos, Kevin R Lynch, Mark D Okusa
Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney. Science translational medicine 14 (658) (2022)
Srinath Pashikanti, Daniel J Foster, Yugesh Kharel, Anne M Brown, David R Bevan, Kevin R Lynch, Webster L Santos
Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues. ACS bio & med chem Au 2 (5) (2022)
Christopher D Sibley, Emily A Morris, Yugesh Kharel, Anne M Brown, Tao Huang, David R Bevan, Kevin R Lynch, Webster L Santos
Discovery of a Small Side Cavity in Sphingosine Kinase 2 that Enhances Inhibitor Potency and Selectivity. Journal of medicinal chemistry 63 (3) (2020)
Yugesh Kharel, Sayeh Agah, Tao Huang, Anna J Mendelson, Oluwafunmilayo T Eletu, Peter Barkey-Bircann, James Gesualdi, Jeffrey S Smith, Webster L Santos, Kevin R Lynch
Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors. PloS one 13 (4) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Kevin R Lynch (K R Lynch)