Kirk James McManus (Kirk J McManus)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 34

Top Venues

Cancers

Cells

Current oncology (Toronto, Ont.)

Molecular cancer therapeutics

University of Manitoba

University of Alberta (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Manitoba Mar 31 2015

Canada

Associate Professor :: Biochemistry & Medical Genetics

CancerCare Manitoba Jun 01 2009

Canada

Senior Scientist :: Research Institute in Oncology & Hematology

University of Manitoba Jun 01 2009 - Mar 30 2015

Canada

Assistant Professor :: Biochemistry & Medical Genetics

Education History

University of Alberta Sep 01 1999 - Dec 31 2004

Canada

PHD :: Experimental Oncology

University of Manitoba Sep 01 1997 - Aug 31 1999

Canada

MSC :: Human Genetics

University of Manitoba Sep 01 1991 - Apr 30 1995

Canada

BSC

Publications

Kailee A Rutherford, Kirk James McManus
PROTACs: Current and Future Potential as a Precision Medicine Strategy to Combat Cancer. Molecular cancer therapeutics (2024)
Kailee A Rutherford, Kirk James McManus
PROTACs: Current and Future Potential as a Precision Medicine Strategy to Combat Cancer. Molecular cancer therapeutics 23 (4) (2024)
Kailee A Rutherford, Kirk James McManus
PROTACs: Current and Future Potential as a Precision Medicine Strategy to Combat Cancer. Molecular cancer therapeutics 23 (4) (2024)
Rubi Campos Gudiño, Kirk James McManus, Sabine Hombach-Klonisch
Aberrant HMGA2 Expression Sustains Genome Instability That Promotes Metastasis and Therapeutic Resistance in Colorectal Cancer. Cancers 15 (6) (2023)
Rubi Campos Gudiño, Kirk James McManus, Sabine Hombach-Klonisch
Aberrant HMGA2 Expression Sustains Genome Instability That Promotes Metastasis and Therapeutic Resistance in Colorectal Cancer. Cancers 15 (6) (2023)
Lucas E L Terceiro, Nnamdi M Ikeogu, Matheus F Lima, Chidalu A Edechi, Barbara E Nickel, Gabor Fischer, Etienne Leygue, Kirk James McManus, Yvonne Myal
Navigating the Blood-Brain Barrier: Challenges and Therapeutic Strategies in Breast Cancer Brain Metastases. International journal of molecular sciences 24 (15) (2023)
Selina Casalino, Sharon Bruce, Kim Serfas, Alon D Altman, Sarah Kean, Pascal Lambert, Kirk James McManus, Jessica N Hartley, Mark William Nachtigal
Exploring the role of a multidisciplinary hereditary gynecologic oncology clinic in epithelial ovarian cancer risk-reducing surgical decision-making practices: A mixed-methods study. Journal of genetic counseling (2023)
Nicole M Neudorf, Laura L Thompson, Zelda Lichtensztejn, Tooba Razi, Kirk James McManus
Reduced SKP2 Expression Adversely Impacts Genome Stability and Promotes Cellular Transformation in Colonic Epithelial Cells. Cells 11 (23) (2022)
Kelcey Winchar, Pascal Lambert, Kirk James McManus, Bernie Chodirker, Sarah Kean, Kim Serfas, Kathleen Margaret Decker, Mark William Nachtigal, Alon D Altman
Referral, Genetic Counselling, and BRCA Testing in the Manitoba High-Grade Serous Ovarian Cancer Population, 2004-2019. Current oncology (Toronto, Ont.) 29 (12) (2022)
Kelcey Winchar, Pascal Lambert, Kirk James McManus, Bernie Chodirker, Sarah Kean, Kim Serfas, Kathleen Margaret Decker, Mark William Nachtigal, Alon D Altman
Referral, Genetic Counselling, and BRCA Testing in the Manitoba High-Grade Serous Ovarian Cancer Population, 2004-2019. Current oncology (Toronto, Ont.) 29 (12) (2022)
Kelcey Winchar, Pascal Lambert, Kirk James McManus, Bernie Chodirker, Sarah Kean, Kim Serfas, Kathleen Margaret Decker, Mark William Nachtigal, Alon D Altman
Referral, Genetic Counselling, and BRCA Testing in the Manitoba High-Grade Serous Ovarian Cancer Population, 2004-2019. Current oncology (Toronto, Ont.) 29 (12) (2022)
Nicole M Neudorf, Laura L Thompson, Zelda Lichtensztejn, Tooba Razi, Kirk James McManus
Reduced SKP2 Expression Adversely Impacts Genome Stability and Promotes Cellular Transformation in Colonic Epithelial Cells. Cells 11 (23) (2022)
Nicole M Neudorf, Laura L Thompson, Zelda Lichtensztejn, Tooba Razi, Kirk James McManus
Reduced SKP2 Expression Adversely Impacts Genome Stability and Promotes Cellular Transformation in Colonic Epithelial Cells. Cells 11 (23) (2022)
Nicole M Neudorf, Laura L Thompson, Zelda Lichtensztejn, Tooba Razi, Kirk James McManus
Reduced SKP2 Expression Adversely Impacts Genome Stability and Promotes Cellular Transformation in Colonic Epithelial Cells. Cells 11 (23) (2022)
Kelcey Winchar, Pascal Lambert, Kirk James McManus, Bernie Chodirker, Sarah Kean, Kim Serfas, Kathleen Margaret Decker, Mark William Nachtigal, Alon D Altman
Referral, Genetic Counselling, and BRCA Testing in the Manitoba High-Grade Serous Ovarian Cancer Population, 2004-2019. Current oncology (Toronto, Ont.) 29 (12) (2022)
Kelcey Winchar, Pascal Lambert, Kirk James McManus, Bernie Chodirker, Sarah Kean, Kim Serfas, Kathleen Margaret Decker, Mark William Nachtigal, Alon D Altman
Referral, Genetic Counselling, and BRCA Testing in the Manitoba High-Grade Serous Ovarian Cancer Population, 2004-2019. Current oncology (Toronto, Ont.) 29 (12) (2022)
Nicole M Neudorf, Laura L Thompson, Zelda Lichtensztejn, Tooba Razi, Kirk James McManus
Reduced SKP2 Expression Adversely Impacts Genome Stability and Promotes Cellular Transformation in Colonic Epithelial Cells. Cells 11 (23) (2022)
Michaela C L Palmer, Nicole M Neudorf, Ally C Farrell, Tooba Razi, Zelda Lichtensztejn, Kirk James McManus
The F-box protein, FBXO7 is required to maintain chromosome stability in humans. Human molecular genetics (2021)
Karolin Heinze, Martin Hölzer, Martin Ungelenk, Melanie Gerth, Juergen Thomale, Regine Heller, Claire R Morden, Kirk James McManus, Alexander S Mosig, Matthias Dürst, Ingo B Runnebaum, Norman Häfner
RUNX3 Transcript Variants Have Distinct Roles in Ovarian Carcinoma and Differently Influence Platinum Sensitivity and Angiogenesis. Cancers 13 (3) (2021)
Chloe Camille Lepage, Michaela Cora Lynn Palmer, Ally Catherina Farrell, Nicole Marie Neudorf, Zelda Lichtensztejn, Mark William Nachtigal, Kirk James McManus
Reduced SKP1 and CUL1 expression underlies increases in Cyclin E1 and chromosome instability in cellular precursors of high-grade serous ovarian cancer. British journal of cancer 124 (10) (2021)
Rubi Campos Gudiño, Ally C Farrell, Nicole M Neudorf, Kirk James McManus
A Comprehensive Assessment of Genetic and Epigenetic Alterations Identifies Frequent Variations Impacting Six Prototypic SCF Complex Members. International journal of molecular sciences 23 (1) (2021)
Laura L Thompson, Kailee A Rutherford, Chloe C Lepage, Kirk James McManus
The SCF Complex Is Essential to Maintain Genome and Chromosome Stability. International journal of molecular sciences 22 (16) (2021)
Lucile M Jeusset, Brent J Guppy, Zelda Lichtensztejn, Darin McDonald, Kirk James McManus
Reduced USP22 Expression Impairs Mitotic Removal of H2B Monoubiquitination, Alters Chromatin Compaction and Induces Chromosome Instability That May Promote Oncogenesis. Cancers 13 (5) (2021)
Raghvendra Vishwakarma, Kirk James McManus
Chromosome Instability; Implications in Cancer Development, Progression, and Clinical Outcomes. Cancers 12 (4) (2020)
Chloe C Lepage, Laura L Thompson, Bradley Larson, Kirk James McManus
An Automated, Single Cell Quantitative Imaging Microscopy Approach to Assess Micronucleus Formation, Genotoxicity and Chromosome Instability. Cells 9 (2) (2020)
Tarik R Leylek, Lucile M Jeusset, Zelda Lichtensztejn, Kirk James McManus
Reduced Expression of Genes Regulating Cohesion Induces Chromosome Instability that May Promote Cancer and Impact Patient Outcomes. Scientific reports 10 (1) (2020)
Lucile M-P Jeusset, Kirk James McManus
Developing Targeted Therapies That Exploit Aberrant Histone Ubiquitination in Cancer. Cells 8 (2) (2019)
Chloe C Lepage, Claire R Morden, Michaela C L Palmer, Mark W Nachtigal, Kirk James McManus
Detecting Chromosome Instability in Cancer: Approaches to Resolve Cell-to-Cell Heterogeneity. Cancers 11 (2) (2019)
Allison K Baergen, Lucile M Jeusset, Zelda Lichtensztejn, Kirk James McManus
Diminished Condensin Gene Expression Drives Chromosome Instability That May Contribute to Colorectal Cancer Pathogenesis. Cancers 11 (8) (2019)
Laura L Thompson, Lucile M-P Jeusset, Chloe C Lepage, Kirk James McManus
Evolving Therapeutic Strategies to Exploit Chromosome Instability in Cancer. Cancers 9 (11) (2017)
Brent J Guppy, Kirk James McManus
Synthetic lethal targeting of RNF20 through PARP1 silencing and inhibition. Cellular oncology (Dordrecht) 40 (3) (2017)
Yasamin Asbaghi, Laura L Thompson, Zelda Lichtensztejn, Kirk James McManus
KIF11 silencing and inhibition induces chromosome instability that may contribute to cancer. Genes, chromosomes & cancer 56 (9) (2017)
Erin N McAndrew, Kirk James McManus
The enigmatic oncogene and tumor suppressor-like properties of RAD54B: Insights into genome instability and cancer. Genes, chromosomes & cancer 56 (7) (2017)
Lucile M-P Jeusset, Kirk James McManus
Ubiquitin Specific Peptidase 22 Regulates Histone H2B Mono-Ubiquitination and Exhibits Both Oncogenic and Tumor Suppressor Roles in Cancer. Cancers 9 (12) (2017)

Kirk James McManus.css-eqlu8i{font-size:small;padding-left:4px;} (Kirk J McManus)

Publication Activity (10 Years)

Top Topics

Top Venues

Kirk James McManus (Kirk J McManus)