Klaus Ley

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 47

Top Topics

Regulatory T Cells

Top Venues

Nature metabolism

Arteriosclerosis, thrombosis, and vascular biology

Journal of immunology (Baltimore, Md. : 1950)

This page only lists publications with an associated author ORCID identifier.

Publications

Amir Khan, Klaus Ley
Immunotherapy for atherosclerosis by targeting pro-inflammatory T cells. Cell research 34 (7) (2024)
Chad Stroope, Felix Sebastian Nettersheim, Brian G Coon, Alexandra C Finney, Martin Alexander Schwartz, Klaus Ley, Oren Rom, Arif Yurdagul
Dysregulated cellular metabolism in atherosclerosis: mediators and therapeutic opportunities. Nature metabolism 6 (4) (2024)
Chad Stroope, Felix Sebastian Nettersheim, Brian G Coon, Alexandra C Finney, Martin Alexander Schwartz, Klaus Ley, Oren Rom, Arif Yurdagul
Dysregulated cellular metabolism in atherosclerosis: mediators and therapeutic opportunities. Nature metabolism (2024)
Amir Khan, Klaus Ley
Immunotherapy for atherosclerosis by targeting pro-inflammatory T cells. Cell research 34 (7) (2024)
Chad Stroope, Felix Sebastian Nettersheim, Brian G Coon, Alexandra C Finney, Martin Alexander Schwartz, Klaus Ley, Oren Rom, Arif Yurdagul
Dysregulated cellular metabolism in atherosclerosis: mediators and therapeutic opportunities. Nature metabolism 6 (4) (2024)
Sujit Silas Armstrong Suthahar, Felix Sebastian Nettersheim, Ahmad Alimadadi, Erpei Wang, Monica Billitti, Natalya Resto-Trujillo, Payel Roy, Catherine C Hedrick, Klaus Ley, Marco Orecchioni
Olfr2-positive macrophages originate from monocytes proliferate in situ and present a pro-inflammatory foamy-like phenotype. Cardiovascular research (2024)
Amir Khan, Klaus Ley
Immunotherapy for atherosclerosis by targeting pro-inflammatory T cells. Cell research 34 (7) (2024)
Chad Stroope, Felix Sebastian Nettersheim, Brian G Coon, Alexandra C Finney, Martin Alexander Schwartz, Klaus Ley, Oren Rom, Arif Yurdagul
Dysregulated cellular metabolism in atherosclerosis: mediators and therapeutic opportunities. Nature metabolism 6 (4) (2024)
Chad Stroope, Felix Sebastian Nettersheim, Brian G Coon, Alexandra C Finney, Martin Alexander Schwartz, Klaus Ley, Oren Rom, Arif Yurdagul
Dysregulated cellular metabolism in atherosclerosis: mediators and therapeutic opportunities. Nature metabolism 6 (4) (2024)
Amir Khan, Payel Roy, Klaus Ley
Breaking tolerance: the autoimmune aspect of atherosclerosis. Nature reviews. Immunology 24 (9) (2024)
Chad Stroope, Felix Sebastian Nettersheim, Brian G Coon, Alexandra C Finney, Martin Alexander Schwartz, Klaus Ley, Oren Rom, Arif Yurdagul
Dysregulated cellular metabolism in atherosclerosis: mediators and therapeutic opportunities. Nature metabolism (2024)
Amir Khan, Klaus Ley
Immunotherapy for atherosclerosis by targeting pro-inflammatory T cells. Cell research (2024)
Amir Khan, Payel Roy, Klaus Ley
Breaking tolerance: the autoimmune aspect of atherosclerosis. Nature reviews. Immunology (2024)
Eduardo Frias-Anaya, Helios Gallego-Gutierrez, Brendan Gongol, Shantel Weinsheimer, Catherine Chinhchu Lai, Marco Orecchioni, Aditya Sriram, Cassandra M Bui, Bliss Nelsen, Preston Hale, Angela Pham, Robert Shenkar, Dorothy DeBiasse, Rhonda Lightle, Romuald Girard, Ying Li, Abhinav Srinath, Richard Daneman, Eric Nudleman, Hao Sun, Mónica Guma, Alexandre Dubrac, Omar A Mesarwi, Klaus Ley, Helen Kim, Issam A Awad, Mark H Ginsberg, Miguel-Alejandro Lopez-Ramirez
Mild Hypoxia Accelerates Cerebral Cavernous Malformation Disease Through CX3CR1-CX3CL1 Signaling. Arteriosclerosis, thrombosis, and vascular biology (2024)
Amir Khan, Klaus Ley
Immunotherapy for atherosclerosis by targeting pro-inflammatory T cells. Cell research 34 (7) (2024)
Tanyaporn Pattarabanjird, Anh Tram Nguyen, Chantel McSkimming, Huy Q Dinh, Melissa A Marshall, Yanal Ghosheh, Rishab Gulati, Chistopher Durant, Jenifer Vallejo, Ryosuke Saigusa, Fabrizio Drago, Thomas V Guy, Katherine Premo, Angela M Taylor, Soumen Paul, Bijoy Kundu, Stuart Berr, Ayelet Gonen, Sotirios Tsimikas, Yury Miller, Shiv Pillai, Klaus Ley, Catherine C Hedrick, Coleen A McNamara
Human circulating CD24 hi marginal zone B cells produce IgM targeting atherogenic antigens and confer protection from vascular disease. Nature cardiovascular research 2 (11) (2023)
Antoine Freuchet, Payel Roy, Sujit Silas Armstrong, Mohammad Oliaei-Motlagh, Sunil Kumar, Marco Orecchioni, Amal J Ali, Amir Khan, Jeffrey Makings, Qingkang Lyu, Holger Winkels, Erpei Wang, Christopher Durant, Yanal Ghosheh, Rishab Gulati, Felix Nettersheim, Klaus Ley
Identification of human exT reg cells as CD16 + CD56 + cytotoxic CD4 + T cells. Nature immunology (2023)
Laura Fusco, Arianna Gazzi, Christopher Eugene Shuck, Marco Orecchioni, Eiman I Ahmed, Linda Giro, Barbara Zavan, Açelya Yılmazer Aktuna, Klaus Ley, Davide Bedognetti, Yury Gogotsi, Lucia Gemma Delogu
V 4 C 3 MXene Immune Profiling and Modulation of T Cell-Dendritic Cell Function and Interaction. Small methods (2023)
Zhichao Fan, Elise Pitmon, Lai Wen, Jacqueline Miller, Erik Ehinger, Rana Herro, Wei Liu, Ju Chen, Zbigniew Mikulski, Douglas J Conrad, Alex Marki, Marco Orecchioni, Puja Kumari, Yanfang Peipei Zhu, Paola M Marcovecchio, Catherine C Hedrick, Craig A Hodges, Vijay A Rathinam, Kepeng Wang, Klaus Ley
Bone Marrow Transplantation Rescues Monocyte Recruitment Defect and Improves Cystic Fibrosis in Mice. Journal of immunology (Baltimore, Md. : 1950) 208 (3) (2022)
Payel Roy, John Sidney, Cecilia S Lindestam Arlehamn, Elizabeth Phillips, Simon A Mallal, Sujit Silas Armstrong Suthahar, Monica Billitti, Paul Rubiro, Daniel Marrama, Fabrizio Drago, Jenifer Vallejo, Vasantika Suryawanshi, Marco Orecchioni, Jeffrey Makings, Paul J Kim, Coleen A McNamara, Bjoern Peters, Alessandro Sette, Klaus Ley
Immunodominant MHC-II (Major Histocompatibility Complex II) Restricted Epitopes in Human Apolipoprotein B. Circulation research 131 (3) (2022)
Felix Sebastian Nettersheim, Sujit Silas Armstrong, Christopher Durant, Rafael Blanco-Dominguez, Payel Roy, Marco Orecchioni, Vasantika Suryawanshi, Klaus Ley
Titration of 124 antibodies using CITE-Seq on human PBMCs. Scientific reports 12 (1) (2022)
Qingkang Lyu, Klaus Ley
How Lymphatic Endothelial Cells Destabilize Regulatory T Cells. Arteriosclerosis, thrombosis, and vascular biology 43 (2) (2022)
Lai Wen, Qingkang Lyu, Klaus Ley, Benjamin Thomas Goult
Structural Basis of β2 Integrin Inside-Out Activation. Cells 11 (19) (2022)
Qingkang Lyu, Klaus Ley
How Lymphatic Endothelial Cells Destabilize Regulatory T Cells. Arteriosclerosis, thrombosis, and vascular biology 43 (2) (2022)
Alex Marki, Klaus Ley
The expanding family of neutrophil-derived extracellular vesicles. Immunological reviews 312 (1) (2022)
Qingkang Lyu, Klaus Ley
How Lymphatic Endothelial Cells Destabilize Regulatory T Cells. Arteriosclerosis, thrombosis, and vascular biology 43 (2) (2022)
Qingkang Lyu, Klaus Ley
How Lymphatic Endothelial Cells Destabilize Regulatory T Cells. Arteriosclerosis, thrombosis, and vascular biology 43 (2) (2022)
Jenifer Vallejo, Clément Cochain, Alma Zernecke, Klaus Ley
Heterogeneity of immune cells in human atherosclerosis revealed by scRNA-Seq. Cardiovascular research 117 (13) (2022)
Qingkang Lyu, Klaus Ley
How Lymphatic Endothelial Cells Destabilize Regulatory T Cells. Arteriosclerosis, thrombosis, and vascular biology (2022)
Ryosuke Saigusa, Jenifer Vallejo, Rishab Gulati, Sujit Silas Armstrong Suthahar, Vasantika Suryawanshi, Ahmad Alimadadi, Jeffrey Makings, Christopher P Durant, Antoine Freuchet, Payel Roy, Yanal Ghosheh, William Pandori, Tanyaporn Pattarabanjird, Fabrizio Drago, Angela Taylor, Coleen A McNamara, Avishai Shemesh, Lewis L Lanier, Catherine C Hedrick, Klaus Ley
Sex Differences in Coronary Artery Disease and Diabetes Revealed by scRNA-Seq and CITE-Seq of Human CD4+ T Cells. International journal of molecular sciences 23 (17) (2022)
Alma Zernecke, Florian Erhard, Tobias Weinberger, Christian Schulz, Klaus Ley, Antoine-Emmanuel Saliba, Clément Cochain
Integrated single-cell analysis based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis. Cardiovascular research (2022)
Ryosuke Saigusa, Christopher P Durant, Vasantika Suryawanshi, Klaus Ley
Single-Cell Antibody Sequencing in Atherosclerosis Research. Methods in molecular biology (Clifton, N.J.) 2419 (2022)
Marco Orecchioni, Kouji Kobiyama, Holger Winkels, Yanal Ghosheh, Sara McArdle, Zbigniew Mikulski, William B Kiosses, Zhichao Fan, Lai Wen, Yunmin Jung, Payel Roy, Amal J Ali, Yukiko Miyamoto, Matthew Mangan, Jeffrey Makings, Zhihao Wang, Angela Denn, Jenifer Vallejo, Michaela Owens, Christopher P Durant, Simon Braumann, Navid Mader, Lin Li, Hiroaki Matsunami, Lars Eckmann, Eicke Latz, Zeneng Wang, Stanley L Hazen, Klaus Ley
Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production. Science (New York, N.Y.) 375 (6577) (2022)
Lai Wen, Markus Moser, Klaus Ley
Molecular mechanisms of leukocyte β2 integrin activation. Blood 139 (24) (2022)
Holger Winkels, Yanal Ghosheh, Kouji Kobiyama, William B Kiosses, Marco Orecchioni, Erik Ehinger, Vasantika Suryawanshi, Sara Herrera-De la Mata, Paola Marchovecchio, Thomas Riffelmacher, Nicolas Thiault, Mitchell Kronenberg, Dennis Wolf, Grégory Seumois, Pandurangan Vijayanand, Klaus Ley
Thymus-Derived CD4+CD8+ Cells Reside in Mediastinal Adipose Tissue and the Aortic Arch. Journal of immunology (Baltimore, Md. : 1950) 207 (11) (2021)
Payel Roy, Marco Orecchioni, Klaus Ley
How the immune system shapes atherosclerosis: roles of innate and adaptive immunity. Nature reviews. Immunology (2021)
Andrea Cugno, Alex Marki, Klaus Ley
Biomechanics of Neutrophil Tethers. Life (Basel, Switzerland) 11 (6) (2021)
Romain Ballet, Martin Brennan, Carolin Brandl, Ningguo Feng, Jeremy Berri, Julian Cheng, Borja Ocón, Amin Alborzian Deh Sheikh, Alex Marki, Yuhan Bi, Clare L Abram, Clifford A Lowell, Takeshi Tsubata, Harry B Greenberg, Matthew Scott Macauley, Klaus Ley, Lars Nitschke, Eugene C Butcher
A CD22-Shp1 phosphatase axis controls integrin β7 display and B cell function in mucosal immunity. Nature immunology 22 (3) (2021)
Yunmin Jung, Lai Wen, Amnon Altman, Klaus Ley
CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition. Nature communications 12 (1) (2021)
Juliana M Navia-Pelaez, Soo-Ho Choi, Luciano Dos Santos Aggum Capettini, Yining Xia, Ayelet Gonen, Colin Agatisa-Boyle, Lauriane Delay, Gilson Gonçalves Dos Santos, Glaucilene F Catroli, Jungsu Kim, Jenny W Lu, Benjamin Saylor, Holger Winkels, Christopher P Durant, Yanal Ghosheh, Graham Beaton, Klaus Ley, Irina Kufareva, Maripat Corr, Tony L Yaksh, Yury I Miller
Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain. The Journal of experimental medicine 218 (7) (2021)
Klaus Ley
Inflammation and Atherosclerosis. Cells 10 (5) (2021)
Amal J Ali, Jeffrey Makings, Klaus Ley
Regulatory T Cell Stability and Plasticity in Atherosclerosis. Cells 9 (12) (2020)
Lai Wen, Zhichao Fan, Zbigniew Mikulski, Klaus Ley
Imaging of the immune system - towards a subcellular and molecular understanding. Journal of cell science 133 (5) (2020)
Ryosuke Saigusa, Holger Winkels, Klaus Ley
T cell subsets and functions in atherosclerosis. Nature reviews. Cardiology 17 (7) (2020)
Klaus Ley
M1 Means Kill; M2 Means Heal. Journal of immunology (Baltimore, Md. : 1950) 199 (7) (2018)
Klaus Ley, Hal M Hoffman, Paul Kubes, Marco Antonio Cassatella, Arturo Zychlinsky, Catherine C Hedrick, Sergio D Catz
Neutrophils: New insights and open questions. Science immunology 3 (30) (2018)
Zhichao Fan, Klaus Ley
Leukocyte Adhesion Deficiency IV. Monocyte Integrin Activation Deficiency in Cystic Fibrosis. American journal of respiratory and critical care medicine 193 (10) (2017)