Kristiina M Huttunen

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 35

Top Venues

Molecular pharmaceutics

Molecules (Basel, Switzerland)

Expert opinion on drug delivery

Scientific reports

University of Eastern Finland

University of Kuopio (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Eastern Finland

Finland

Reseach Fellow of Academy of Finland :: School of Pharmacy

University of Eastern Finland

Finland

Postdoctoral Researcher of Academy of Finland :: School of Pharmacy

University of Eastern Finland

Finland

Postdoctoral Research Scientist :: School of Pharmacy

University of Auckland

New Zealand

Postdoctoral Research Fellow :: Auckland Cancer Society Researc Centre

University of Kuopio

Finland

Research Scientist (Ph.D. student) :: Faculty of Pharmacy

University of Kuopio

Finland

Research Scientist (undergraduate student) :: Faculty of Pharmacy

Education History

University of Kuopio

Finland

PHD :: Faculty of Pharmacy

University of Kuopio

Finland

MSC :: Faculty of Natural and Environmental Sciences

University of Jyväskylä

Finland

BSC :: Faculty of Mathematics and Science

Publications

Kristiina M Huttunen
Improving drug delivery to the brain: the prodrug approach. Expert opinion on drug delivery (2024)
Eva Ramsay, Ahmed B Montaser, Kanako Niitsu, Arto Urtti, Seppo Auriola, Kristiina M Huttunen, Yasuo Uchida, Heidi Kidron, Tetsuya Terasaki
Transporter Protein Expression of Corneal Epithelium in Rabbit and Porcine: Evaluation of Models for Ocular Drug Transport Study. Molecular pharmaceutics 21 (7) (2024)
Kristiina M Huttunen
Improving drug delivery to the brain: the prodrug approach. Expert opinion on drug delivery 21 (5) (2024)
Eva Ramsay, Ahmed B Montaser, Kanako Niitsu, Arto Urtti, Seppo Auriola, Kristiina M Huttunen, Yasuo Uchida, Heidi Kidron, Tetsuya Terasaki
Transporter Protein Expression of Corneal Epithelium in Rabbit and Porcine: Evaluation of Models for Ocular Drug Transport Study. Molecular pharmaceutics (2024)
Kristiina M Huttunen
Improving drug delivery to the brain: the prodrug approach. Expert opinion on drug delivery (2024)
Kristiina M Huttunen
Improving drug delivery to the brain: the prodrug approach. Expert opinion on drug delivery 21 (5) (2024)
Johanna Huttunen, Thales Kronenberger, Ahmed B Montaser, Adéla Králová, Tetsuya Terasaki, Antti Poso, Kristiina M Huttunen
Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs. Molecular pharmaceutics (2023)
Johanna Huttunen, Thales Kronenberger, Ahmed B Montaser, Adéla Králová, Tetsuya Terasaki, Antti Poso, Kristiina M Huttunen
Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs. Molecular pharmaceutics 20 (2) (2023)
Johanna Huttunen, Thales Kronenberger, Ahmed B Montaser, Adéla Králová, Tetsuya Terasaki, Antti Poso, Kristiina M Huttunen
Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs. Molecular pharmaceutics 20 (2) (2023)
Johanna Huttunen, Thales Kronenberger, Ahmed B Montaser, Adéla Králová, Tetsuya Terasaki, Antti Poso, Kristiina M Huttunen
Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs. Molecular pharmaceutics 20 (2) (2023)
Arun Kumar Tonduru, Seyed Hamed Maljaei, Santosh Kumar Adla, Landry Anamea, Janne Tampio, Adéla Králová, Aaro J Jalkanen, Catarina Espada, Inês Falcato Santos, Ahmed B Montaser, Jarkko Rautio, Thales Kronenberger, Antti Poso, Kristiina M Huttunen
Targeting Glial Cells by Organic Anion-Transporting Polypeptide 1C1 (OATP1C1)-Utilizing l-Thyroxine-Derived Prodrugs. Journal of medicinal chemistry (2023)
Johanna Huttunen, Thales Kronenberger, Ahmed B Montaser, Adéla Králová, Tetsuya Terasaki, Antti Poso, Kristiina M Huttunen
Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs. Molecular pharmaceutics 20 (2) (2023)
Arun Kumar Tonduru, Santosh Kumar Adla, Kristiina M Huttunen, Thales Kronenberger, Antti Poso
Comparative Modelling of Organic Anion Transporting Polypeptides: Structural Insights and Comparison of Binding Modes. Molecules (Basel, Switzerland) 27 (23) (2022)
Arun Kumar Tonduru, Santosh Kumar Adla, Kristiina M Huttunen, Thales Kronenberger, Antti Poso
Comparative Modelling of Organic Anion Transporting Polypeptides: Structural Insights and Comparison of Binding Modes. Molecules (Basel, Switzerland) 27 (23) (2022)
Kristiina M Huttunen, Tetsuya Terasaki, Arto Urtti, Ahmed B Montaser, Yasuo Uchida
Pharmacoproteomics of Brain Barrier Transporters and Substrate Design for the Brain Targeted Drug Delivery. Pharmaceutical research 39 (7) (2022)
Agnieszka Zajda, Joanna Sikora, Kristiina M Huttunen, Magdalena Markowicz-Piasecka
Structural Comparison of Sulfonamide-Based Derivatives That Can Improve Anti-Coagulation Properties of Metformin. International journal of molecular sciences 23 (8) (2022)
Johanna Huttunen, Santosh Kumar Adla, Magdalena Markowicz-Piasecka, Kristiina M Huttunen
Increased/Targeted Brain (Pro)Drug Delivery via Utilization of Solute Carriers (SLCs). Pharmaceutics 14 (6) (2022)
Katayun Bahrami, Juulia Järvinen, Tuomo Laitinen, Mika Reinisalo, Paavo Honkakoski, Antti Poso, Kristiina M Huttunen, Jarkko Rautio
Structural Features Affecting the Interactions and Transportability of LAT1-Targeted Phenylalanine Drug Conjugates. Molecular pharmaceutics (2022)
Janne Tampio, Magdalena Markowicz-Piasecka, Ahmed B Montaser, Jaana Rysä, Anu Kauppinen, Kristiina M Huttunen
L-type Amino Acid Transporter 1 Utilizing Ferulic Acid Derivatives Show Increased Drug Delivery in the Mouse Pancreas Along with Decreased Lipid Peroxidation and Prostaglandin Production. Molecular pharmaceutics 19 (11) (2022)
Arun Kumar Tonduru, Santosh Kumar Adla, Kristiina M Huttunen, Thales Kronenberger, Antti Poso
Comparative Modelling of Organic Anion Transporting Polypeptides: Structural Insights and Comparison of Binding Modes. Molecules (Basel, Switzerland) 27 (23) (2022)
Arun Kumar Tonduru, Santosh Kumar Adla, Kristiina M Huttunen, Thales Kronenberger, Antti Poso
Comparative Modelling of Organic Anion Transporting Polypeptides: Structural Insights and Comparison of Binding Modes. Molecules (Basel, Switzerland) 27 (23) (2022)
Julie A Spicer, Kristiina M Huttunen, Jiney Jose, Ivo Dimitrov, Hedieh Akhlaghi, Vivien R Sutton, Ilia Voskoboinik, Joseph Trapani
Small Molecule Inhibitors of Lymphocyte Perforin as Focused Immunosuppressants for Infection and Autoimmunity. Journal of medicinal chemistry 65 (21) (2022)
Johanna Huttunen, Mahmoud Agami, Janne Tampio, Ahmed B Montaser, Kristiina M Huttunen
Comparison of Experimental Strategies to Study l-Type Amino Acid Transporter 1 (LAT1) Utilization by Ligands. Molecules (Basel, Switzerland) 27 (1) (2021)
Santosh Kumar Adla, Arun Kumar Tonduru, Thales Kronenberger, Eva Kudova, Antti Poso, Kristiina M Huttunen
Neurosteroids: Structure-Uptake Relationships and Computational Modeling of Organic Anion Transporting Polypeptides (OATP)1A2. Molecules (Basel, Switzerland) 26 (18) (2021)
Magdalena Markowicz-Piasecka, Johanna Huttunen, Ahmed Montaser, Kristiina M Huttunen
Hemocompatible LAT1-inhibitor can induce apoptosis in cancer cells without affecting brain amino acid homeostasis. Apoptosis : an international journal on programmed cell death 25 (5-6) (2021)
Magdalena Markowicz-Piasecka, Johanna Huttunen, Ahmed Montaser, Santosh Kumar Adla, Seppo Auriola, Marko Lehtonen, Kristiina M Huttunen
Ganciclovir and Its Hemocompatible More Lipophilic Derivative Can Enhance the Apoptotic Effects of Methotrexate by Inhibiting Breast Cancer Resistance Protein (BCRP). International journal of molecular sciences 22 (14) (2021)
Jelena Matović, Juulia Järvinen, Iris K Sokka, Surachet Imlimthan, Jan-Erik Raitanen, Ahmed B Montaser, Hannu Maaheimo, Kristiina M Huttunen, Sirpa Peräniemi, Anu J Airaksinen, Mirkka P Sarparanta, Mikael P Johansson, Jarkko Rautio, Filip S Ekholm
Exploring the Biochemical Foundations of a Successful GLUT1-Targeting Strategy to BNCT: Chemical Synthesis and In Vitro Evaluation of the Entire Positional Isomer Library of ortho-Carboranylmethyl-Bearing Glucoconjugates. Molecular pharmaceutics 18 (1) (2020)
Jelena Matović, Juulia Järvinen, Helena C Bland, Iris K Sokka, Surachet Imlimthan, Ruth Mateu Ferrando, Kristiina M Huttunen, Juri M Timonen, Sirpa Peräniemi, Olli Aitio, Anu J Airaksinen, Mirkka P Sarparanta, Mikael P Johansson, Jarkko Rautio, Filip S Ekholm
Addressing the Biochemical Foundations of a Glucose-Based "Trojan Horse"-Strategy to Boron Neutron Capture Therapy: From Chemical Synthesis to In Vitro Assessment. Molecular pharmaceutics 17 (10) (2020)
Ahmed Montaser, Marko Lehtonen, Mikko Gynther, Kristiina M Huttunen
L-Type Amino Acid Transporter 1-Utilizing Prodrugs of Ketoprofen Can Efficiently Reduce Brain Prostaglandin Levels. Pharmaceutics 12 (4) (2020)
Ahmed B Montaser, Juulia Järvinen, Susanne Löffler, Johanna Huttunen, Seppo Auriola, Marko Lehtonen, Aaro Jalkanen, Kristiina M Huttunen
L-Type Amino Acid Transporter 1 Enables the Efficient Brain Delivery of Small-Sized Prodrug across the Blood-Brain Barrier and into Human and Mouse Brain Parenchymal Cells. ACS chemical neuroscience 11 (24) (2020)
Janne Tampio, Johanna Huttunen, Ahmed Montaser, Kristiina M Huttunen
Targeting of Perforin Inhibitor into the Brain Parenchyma Via a Prodrug Approach Can Decrease Oxidative Stress and Neuroinflammation and Improve Cell Survival. Molecular neurobiology 57 (11) (2020)
Elena Puris, Mikko Gynther, Elizabeth C M de Lange, Seppo Auriola, Margareta Hammarlund-Udenaes, Kristiina M Huttunen, Irena Loryan
Mechanistic Study on the Use of the l-Type Amino Acid Transporter 1 for Brain Intracellular Delivery of Ketoprofen via Prodrug: A Novel Approach Supporting the Development of Prodrugs for Intracellular Targets. Molecular pharmaceutics 16 (7) (2019)
Ahmed Montaser, Johanna Huttunen, Sherihan Abdelhamid Ibrahim, Kristiina M Huttunen
Astrocyte-Targeted Transporter-Utilizing Derivatives of Ferulic Acid Can Have Multifunctional Effects Ameliorating Inflammation and Oxidative Stress in the Brain. Oxidative medicine and cellular longevity 2019 (2019)
Johanna Huttunen, Soile Peltokangas, Mikko Gynther, Teemu Natunen, Mikko Hiltunen, Seppo Auriola, Marika Ruponen, Kati-Sisko Vellonen, Kristiina M Huttunen
L-Type Amino Acid Transporter 1 (LAT1/Lat1)-Utilizing Prodrugs Can Improve the Delivery of Drugs into Neurons, Astrocytes and Microglia. Scientific reports 9 (1) (2019)
Magdalena Markowicz-Piasecka, Kristiina M Huttunen, Marlena Broncel, Joanna Sikora
Sulfenamide and Sulfonamide Derivatives of Metformin - A New Option to Improve Endothelial Function and Plasma Haemostasis. Scientific reports 9 (1) (2019)

Kristiina M Huttunen.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Kristiina M Huttunen