Antti Poso

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 84

Top Venues

Journal of medicinal chemistry

Journal of chemical information and modeling

ChemMedChem

Molecular pharmaceutics

University of Eastern Finland

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Eastern Finland Jan 01 2010

Finland

Professor :: School of Pharmacy

Publications

Azam Rashidian, Jan Dušek, Martin Drastik, Lucie Smutná, Kristin Fritsche, Albert Braeuning, Dirk Pijnenburg, Rinie van Beuningen, Paavo Honkakoski, Antti Poso, Thales Kronenberger, Petr Pavek
Filling the Blank Space: Branched 4-Nonylphenol Isomers Are Responsible for Robust Constitutive Androstane Receptor (CAR) Activation by Nonylphenol. Environmental science & technology 58 (16) (2024)
Mateus Sá Magalhães Serafim, Thales Kronenberger, Rafael Eduardo Oliveira Rocha, Amanda Del Rio Abreu Rosa, Thaysa Lara Gonçalves Mello, Antti Poso, Rafaela Salgado Ferreira, Jonatas Santos Abrahão, Erna Geessien Kroon, Bruno Eduardo Fernandes Mota, Vinícius Gonçalves Maltarollo
Aminopyrimidine Derivatives as Multiflavivirus Antiviral Compounds Identified from a Consensus Virtual Screening Approach. Journal of chemical information and modeling 64 (2) (2024)
Azam Rashidian, Jan Dušek, Martin Drastik, Lucie Smutná, Kristin Fritsche, Albert Braeuning, Dirk Pijnenburg, Rinie van Beuningen, Paavo Honkakoski, Antti Poso, Thales Kronenberger, Petr Pavek
Filling the Blank Space: Branched 4-Nonylphenol Isomers Are Responsible for Robust Constitutive Androstane Receptor (CAR) Activation by Nonylphenol. Environmental science & technology 58 (16) (2024)
Marc U Engelhardt, Markus O Zimmermann, Marcel Dammann, Jason Stahlecker, Antti Poso, Thales Kronenberger, Conrad Kunick, Thilo Stehle, Frank M Boeckler
Halogen Bonding on Water─A Drop in the Ocean? Journal of chemical theory and computation (2024)
Philipp Flury, Julian Breidenbach, Nadine Krüger, Rabea Voget, Laura Schäkel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert, Katharina Sylvester, Cheila Rocha, Raphael Ditzinger, Alexander Rasch, Stefan Pöhlmann, Thales Kronenberger, Antti Poso, Katharina Rox, Stefan A Laufer, Christa Elisabeth Müller, Michael Gütschow, Thanigaimalai Pillaiyar
Correction to "Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity". ACS pharmacology & translational science 7 (4) (2024)
Marcel Rak, Amelie Menge, Roberta Tesch, Lena M Berger, Dimitrios-Ilias Balourdas, Ekaterina Shevchenko, Andreas Krämer, Lewis Elson, Benedict-Tilmann Berger, Ismahan Abdi, Laurenz M Wahl, Antti Poso, Astrid Kaiser, Thomas Hanke, Thales Kronenberger, Andreas C Joerger, Susanne Müller, Stefan Knapp
Development of Selective Pyrido[2,3- d ]pyrimidin-7(8 H )-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors. Journal of medicinal chemistry 67 (5) (2024)
Mateus Sá Magalhães Serafim, Thales Kronenberger, Rafael Eduardo Oliveira Rocha, Amanda Del Rio Abreu Rosa, Thaysa Lara Gonçalves Mello, Antti Poso, Rafaela Salgado Ferreira, Jonatas Santos Abrahão, Erna Geessien Kroon, Bruno Eduardo Fernandes Mota, Vinícius Gonçalves Maltarollo
Aminopyrimidine Derivatives as Multiflavivirus Antiviral Compounds Identified from a Consensus Virtual Screening Approach. Journal of chemical information and modeling 64 (2) (2024)
Florian Wittlinger, Blessing C Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D Pham, Ilse K Schaeffner, Brandon T Oligny, Surbhi P Chitnis, Tyler S Beyett, Alexander Rasch, Brian Buckley, Daniel A Urul, Tatiana Shaurova, Earl W May, Erik M Schaefer, Michael J Eck, Pamela A Hershberger, Antti Poso, Stefan A Laufer, David E Heppner
Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors. Communications chemistry 7 (1) (2024)
Florian Wittlinger, Blessing C Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D Pham, Ilse K Schaeffner, Brandon T Oligny, Surbhi P Chitnis, Tyler S Beyett, Alexander Rasch, Brian Buckley, Daniel A Urul, Tatiana Shaurova, Earl W May, Erik M Schaefer, Michael J Eck, Pamela A Hershberger, Antti Poso, Stefan A Laufer, David E Heppner
Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors. Communications chemistry 7 (1) (2024)
Philipp Flury, Julian Breidenbach, Nadine Krüger, Rabea Voget, Laura Schäkel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert, Katharina Sylvester, Cheila Rocha, Raphael Ditzinger, Alexander Rasch, Stefan Pöhlmann, Thales Kronenberger, Antti Poso, Katharina Rox, Stefan A Laufer, Christa Elisabeth Müller, Michael Gütschow, Thanigaimalai Pillaiyar
Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity. ACS pharmacology & translational science 7 (2) (2024)
Marcel Rak, Amelie Menge, Roberta Tesch, Lena M Berger, Dimitrios-Ilias Balourdas, Ekaterina Shevchenko, Andreas Krämer, Lewis Elson, Benedict-Tilmann Berger, Ismahan Abdi, Laurenz M Wahl, Antti Poso, Astrid Kaiser, Thomas Hanke, Thales Kronenberger, Andreas C Joerger, Susanne Müller, Stefan Knapp
Development of Selective Pyrido[2,3- d ]pyrimidin-7(8 H )-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors. Journal of medicinal chemistry (2024)
Mateus Sá Magalhães Serafim, Thales Kronenberger, Rafael Eduardo Oliveira Rocha, Amanda Del Rio Abreu Rosa, Thaysa Lara Gonçalves Mello, Antti Poso, Rafaela Salgado Ferreira, Jonatas Santos Abrahão, Erna Geessien Kroon, Bruno Eduardo Fernandes Mota, Vinícius Gonçalves Maltarollo
Aminopyrimidine Derivatives as Multiflavivirus Antiviral Compounds Identified from a Consensus Virtual Screening Approach. Journal of chemical information and modeling (2024)
Mateus Sá Magalhães Serafim, Thales Kronenberger, Rafael Eduardo Oliveira Rocha, Amanda Del Rio Abreu Rosa, Thaysa Lara Gonçalves Mello, Antti Poso, Rafaela Salgado Ferreira, Jonatas Santos Abrahão, Erna Geessien Kroon, Bruno Eduardo Fernandes Mota, Vinícius Gonçalves Maltarollo
Aminopyrimidine Derivatives as Multiflavivirus Antiviral Compounds Identified from a Consensus Virtual Screening Approach. Journal of chemical information and modeling 64 (2) (2024)
Stephan Spahn, Fabian Kleinhenz, Ekaterina Shevchenko, Aaron Stahl, Yvonne Rasen, Christine Geisler, Kristina Ruhm, Marion Klaumuenzer, Thales Kronenberger, Stefan A Laufer, Holly Sundberg-Malek, Khac Cuong Bui, Marius Horger, Saskia Biskup, Heike Bantel, Markus Templin, Nisar P Malek, Antti Poso, Michael Bitzer
The molecular interaction pattern of lenvatinib enables inhibition of wild-type or kinase-mutated FGFR2-driven cholangiocarcinoma. Nature communications 15 (1) (2024)
Manuel Sigle, Anne-Katrin Rohlfing, Melanie Cruz Santos, Timo Kopp, Konstantin Krutzke, Vincent Gidlund, Ferdinand Kollotzek, Julia Marzi, Saskia von Ungern-Sternberg, Antti Poso, Mathias Heikenwälder, Katja Schenke-Layland, Peter Seizer, Julia Möllmann, Nikolaus Marx, Robert Feil, Susanne Feil, Robert Lukowski, Oliver Borst, Tilman E Schäffer, Karin Anne Lydia Müller, Meinrad P Gawaz, David Heinzmann
Targeting Cyclophilin A in the Cardiac Microenvironment Preserves Heart Function and Structure in Failing Hearts. Circulation research (2024)
Florian Wittlinger, Blessing C Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D Pham, Ilse K Schaeffner, Brandon T Oligny, Surbhi P Chitnis, Tyler S Beyett, Alexander Rasch, Brian Buckley, Daniel A Urul, Tatiana Shaurova, Earl W May, Erik M Schaefer, Michael J Eck, Pamela A Hershberger, Antti Poso, Stefan A Laufer, David E Heppner
Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors. Communications chemistry 7 (1) (2024)
Stephan Spahn, Fabian Kleinhenz, Ekaterina Shevchenko, Aaron Stahl, Yvonne Rasen, Christine Geisler, Kristina Ruhm, Marion Klaumuenzer, Thales Kronenberger, Stefan A Laufer, Holly Sundberg-Malek, Khac Cuong Bui, Marius Horger, Saskia Biskup, Heike Bantel, Markus Templin, Nisar P Malek, Antti Poso, Michael Bitzer
The molecular interaction pattern of lenvatinib enables inhibition of wild-type or kinase-mutated FGFR2-driven cholangiocarcinoma. Nature communications 15 (1) (2024)
Azam Rashidian, Jan Dušek, Martin Drastik, Lucie Smutná, Kristin Fritsche, Albert Braeuning, Dirk Pijnenburg, Rinie van Beuningen, Paavo Honkakoski, Antti Poso, Thales Kronenberger, Petr Pavek
Filling the Blank Space: Branched 4-Nonylphenol Isomers Are Responsible for Robust Constitutive Androstane Receptor (CAR) Activation by Nonylphenol. Environmental science & technology 58 (16) (2024)
Azam Rashidian, Jan Dušek, Martin Drastik, Lucie Smutná, Kristin Fritsche, Albert Braeuning, Dirk Pijnenburg, Rinie van Beuningen, Paavo Honkakoski, Antti Poso, Thales Kronenberger, Petr Pavek
Filling the Blank Space: Branched 4-Nonylphenol Isomers Are Responsible for Robust Constitutive Androstane Receptor (CAR) Activation by Nonylphenol. Environmental science & technology (2024)
Stephan Spahn, Fabian Kleinhenz, Ekaterina Shevchenko, Aaron Stahl, Yvonne Rasen, Christine Geisler, Kristina Ruhm, Marion Klaumuenzer, Thales Kronenberger, Stefan A Laufer, Holly Sundberg-Malek, Khac Cuong Bui, Marius Horger, Saskia Biskup, Heike Bantel, Markus Templin, Nisar P Malek, Antti Poso, Michael Bitzer
The molecular interaction pattern of lenvatinib enables inhibition of wild-type or kinase-mutated FGFR2-driven cholangiocarcinoma. Nature communications 15 (1) (2024)
Florian Wittlinger, Blessing C Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D Pham, Ilse K Schaeffner, Brandon T Oligny, Surbhi P Chitnis, Tyler S Beyett, Alexander Rasch, Brian Buckley, Daniel A Urul, Tatiana Shaurova, Earl W May, Erik M Schaefer, Michael J Eck, Pamela A Hershberger, Antti Poso, Stefan A Laufer, David E Heppner
Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors. Communications chemistry 7 (1) (2024)
Marcel Rak, Amelie Menge, Roberta Tesch, Lena M Berger, Dimitrios-Ilias Balourdas, Ekaterina Shevchenko, Andreas Krämer, Lewis Elson, Benedict-Tilmann Berger, Ismahan Abdi, Laurenz M Wahl, Antti Poso, Astrid Kaiser, Thomas Hanke, Thales Kronenberger, Andreas C Joerger, Susanne Müller, Stefan Knapp
Development of Selective Pyrido[2,3- d ]pyrimidin-7(8 H )-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors. Journal of medicinal chemistry 67 (5) (2024)
Stephan Spahn, Fabian Kleinhenz, Ekaterina Shevchenko, Aaron Stahl, Yvonne Rasen, Christine Geisler, Kristina Ruhm, Marion Klaumuenzer, Thales Kronenberger, Stefan A Laufer, Holly Sundberg-Malek, Khac Cuong Bui, Marius Horger, Saskia Biskup, Heike Bantel, Markus Templin, Nisar P Malek, Antti Poso, Michael Bitzer
The molecular interaction pattern of lenvatinib enables inhibition of wild-type or kinase-mutated FGFR2-driven cholangiocarcinoma. Nature communications 15 (1) (2024)
Philipp Flury, Julian Breidenbach, Nadine Krüger, Rabea Voget, Laura Schäkel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert, Katharina Sylvester, Cheila Rocha, Raphael Ditzinger, Alexander Rasch, Stefan Pöhlmann, Thales Kronenberger, Antti Poso, Katharina Rox, Stefan A Laufer, Christa Elisabeth Müller, Michael Gütschow, Thanigaimalai Pillaiyar
Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity. ACS pharmacology & translational science 7 (2) (2024)
Florian Wittlinger, Blessing C Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D Pham, Ilse K Schaeffner, Brandon T Oligny, Surbhi P Chitnis, Tyler S Beyett, Alexander Rasch, Brian Buckley, Daniel A Urul, Tatiana Shaurova, Earl W May, Erik M Schaefer, Michael J Eck, Pamela A Hershberger, Antti Poso, Stefan A Laufer, David E Heppner
Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors. Communications chemistry 7 (1) (2024)
Philipp Flury, Julian Breidenbach, Nadine Krüger, Rabea Voget, Laura Schäkel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert, Katharina Sylvester, Cheila Rocha, Raphael Ditzinger, Alexander Rasch, Stefan Pöhlmann, Thales Kronenberger, Antti Poso, Katharina Rox, Stefan A Laufer, Christa Elisabeth Müller, Michael Gütschow, Thanigaimalai Pillaiyar
Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity. ACS pharmacology & translational science 7 (2) (2024)
Johanna Huttunen, Thales Kronenberger, Ahmed B Montaser, Adéla Králová, Tetsuya Terasaki, Antti Poso, Kristiina M Huttunen
Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs. Molecular pharmaceutics (2023)
Glaucio Valdameri, Diogo Henrique Kita, Julia de Paula Dutra, Diego Lima Gomes, Arun Kumar Tonduru, Thales Kronenberger, Bruno Gavinho, Izadora Volpato Rossi, Mariana Mazetto de Carvalho, Basile Pérès, Ingrid Fatima Zattoni, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Rilton Alves de Freitas, Antti Poso, Suresh V Ambudkar, Marcel I Ramirez, Ahcène Boumendjel, Vivian Rotuno Moure
Characterization of Potent ABCG2 Inhibitor Derived from Chromone: From the Mechanism of Inhibition to Human Extracellular Vesicles for Drug Delivery. Pharmaceutics 15 (4) (2023)
Johanna Huttunen, Thales Kronenberger, Ahmed B Montaser, Adéla Králová, Tetsuya Terasaki, Antti Poso, Kristiina M Huttunen
Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs. Molecular pharmaceutics 20 (2) (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Johanna Huttunen, Thales Kronenberger, Ahmed B Montaser, Adéla Králová, Tetsuya Terasaki, Antti Poso, Kristiina M Huttunen
Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs. Molecular pharmaceutics 20 (2) (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Glaucio Monteiro Ferreira, Thales Kronenberger, Vinícius Gonçalves Maltarollo, Antti Poso, Fernando de Moura Gatti, Vitor Medeiros Almeida, Sandro Roberto Marana, Carla Duque Lopes, Daiane Yukie Tezuka, Sérgio de Albuquerque, Flavio da Silva Emery, Gustavo Henrique Goulart Trossini
Trypanosoma cruzi Sirtuin 2 as a Relevant Druggable Target: New Inhibitors Developed by Computer-Aided Drug Design. Pharmaceuticals (Basel, Switzerland) 16 (3) (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Glaucio Valdameri, Diogo Henrique Kita, Julia de Paula Dutra, Diego Lima Gomes, Arun Kumar Tonduru, Thales Kronenberger, Bruno Gavinho, Izadora Volpato Rossi, Mariana Mazetto de Carvalho, Basile Pérès, Ingrid Fatima Zattoni, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Rilton Alves de Freitas, Antti Poso, Suresh V Ambudkar, Marcel I Ramirez, Ahcène Boumendjel, Vivian Rotuno Moure
Characterization of Potent ABCG2 Inhibitor Derived from Chromone: From the Mechanism of Inhibition to Human Extracellular Vesicles for Drug Delivery. Pharmaceutics 15 (4) (2023)
Vinícius Gonçalves Maltarollo, Elany Barbosa da Silva, Thales Kronenberger, Marina Mol Sena Andrade, Gabriel V de Lima Marques, Nereu J Cândido Oliveira, Lucianna H Santos, Celso de Oliveira Rezende Júnior, Ana C Cassiano Martinho, Danielle Skinner, Pavla Fajtová, Thaís H M Fernandes, Eduardo da Silveira Dos Santos, Poliana A Rodrigues Gazolla, Ana P Martins de Souza, Milene Lopes da Silva, Fabíola S Dos Santos, Stefânia N Lavorato, Ana C Oliveira Bretas, Diogo Teixeira Carvalho, Lucas Lopardi Franco, Stephanie Luedtke, Miriam A Giardini, Antti Poso, Luiz C Dias, Larissa M Podust, Ricardo J Alves, James McKerrow, Saulo F Andrade, Róbson R Teixeira, Jair L Siqueira-Neto, Anthony O'Donoghue, Renata Barbosa de Oliveira, Rafaela Salgado Ferreira
Structure-based discovery of thiosemicarbazones as SARS-CoV-2 main protease inhibitors. Future medicinal chemistry (2023)
Johanna Huttunen, Thales Kronenberger, Ahmed B Montaser, Adéla Králová, Tetsuya Terasaki, Antti Poso, Kristiina M Huttunen
Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs. Molecular pharmaceutics 20 (2) (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Glaucio Valdameri, Diogo Henrique Kita, Julia de Paula Dutra, Diego Lima Gomes, Arun Kumar Tonduru, Thales Kronenberger, Bruno Gavinho, Izadora Volpato Rossi, Mariana Mazetto de Carvalho, Basile Pérès, Ingrid Fatima Zattoni, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Rilton Alves de Freitas, Antti Poso, Suresh V Ambudkar, Marcel I Ramirez, Ahcène Boumendjel, Vivian Rotuno Moure
Characterization of Potent ABCG2 Inhibitor Derived from Chromone: From the Mechanism of Inhibition to Human Extracellular Vesicles for Drug Delivery. Pharmaceutics 15 (4) (2023)
Glaucio Monteiro Ferreira, Thales Kronenberger, Vinícius Gonçalves Maltarollo, Antti Poso, Fernando de Moura Gatti, Vitor Medeiros Almeida, Sandro Roberto Marana, Carla Duque Lopes, Daiane Yukie Tezuka, Sérgio de Albuquerque, Flavio da Silva Emery, Gustavo Henrique Goulart Trossini
Trypanosoma cruzi Sirtuin 2 as a Relevant Druggable Target: New Inhibitors Developed by Computer-Aided Drug Design. Pharmaceuticals (Basel, Switzerland) 16 (3) (2023)
Toni Sivula, Laxman Yetukuri, Tuomo Kalliokoski, Heikki Käsnänen, Antti Poso, Ina Poehner
Machine Learning-Boosted Docking Enables the Efficient Structure-Based Virtual Screening of Giga-Scale Enumerated Chemical Libraries. Journal of chemical information and modeling (2023)
David E Heppner, Florian Wittlinger, Blessing Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin Pham, Ilse Schaeffner, Brandon T Oligny, Surbhi Chitnis, Tyler Beyett, Alexander Rasch, Brian Buckley, Daniel Urul, Tatiana Shaurova, Earl May, Erik Schaefer, Michael J Eck, Pamela Hershberger, Antti Poso, Stefan A Laufer
Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors. Research square (2023)
Xiaodan Ouyang, Paul M D'Agostino, Matti Wahlsten, Endrews Delbaje, Jouni Kalevi Jokela, Perttu Permi, Greta Gaiani, Antti Poso, Piia Bartos, Tobias A M Gulder, Hannu Koistinen, David Peter Fewer
Direct pathway cloning and expression of the radiosumin biosynthetic gene cluster. Organic & biomolecular chemistry (2023)
Maurício Temotheo Tavares, Arne Krüger, Sun L Rei Yan, Karoline B Waitman, Vinicius de Morais Gomes, Daffiny Sumam de Oliveira, Franciarli Paz, Sebastian Hilscher, Mike Schutkowski, Wolfgang Sippl, Claudia Ruiz, Monica F Z J Toledo, Neuza Mariko Aymoto Hassimotto, João Agostinho Machado-Neto, Antti Poso, Michael D Cameron, Thomas D Bannister, Giuseppe Palmisano, Carsten Wrenger, Thales Kronenberger, Roberto Parise-Filho
1,3-Diphenylureido hydroxamate as a promising scaffold for generation of potent antimalarial histone deacetylase inhibitors. Scientific reports 13 (1) (2023)
Arun Kumar Tonduru, Seyed Hamed Maljaei, Santosh Kumar Adla, Landry Anamea, Janne Tampio, Adéla Králová, Aaro J Jalkanen, Catarina Espada, Inês Falcato Santos, Ahmed B Montaser, Jarkko Rautio, Thales Kronenberger, Antti Poso, Kristiina M Huttunen
Targeting Glial Cells by Organic Anion-Transporting Polypeptide 1C1 (OATP1C1)-Utilizing l-Thyroxine-Derived Prodrugs. Journal of medicinal chemistry (2023)
Glaucio Valdameri, Diogo Henrique Kita, Julia de Paula Dutra, Diego Lima Gomes, Arun Kumar Tonduru, Thales Kronenberger, Bruno Gavinho, Izadora Volpato Rossi, Mariana Mazetto de Carvalho, Basile Pérès, Ingrid Fatima Zattoni, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Rilton Alves de Freitas, Antti Poso, Suresh V Ambudkar, Marcel I Ramirez, Ahcène Boumendjel, Vivian Rotuno Moure
Characterization of Potent ABCG2 Inhibitor Derived from Chromone: From the Mechanism of Inhibition to Human Extracellular Vesicles for Drug Delivery. Pharmaceutics 15 (4) (2023)
Glaucio Monteiro Ferreira, Thales Kronenberger, Vinícius Gonçalves Maltarollo, Antti Poso, Fernando de Moura Gatti, Vitor Medeiros Almeida, Sandro Roberto Marana, Carla Duque Lopes, Daiane Yukie Tezuka, Sérgio de Albuquerque, Flavio da Silva Emery, Gustavo Henrique Goulart Trossini
Trypanosoma cruzi Sirtuin 2 as a Relevant Druggable Target: New Inhibitors Developed by Computer-Aided Drug Design. Pharmaceuticals (Basel, Switzerland) 16 (3) (2023)
Johanna Huttunen, Thales Kronenberger, Ahmed B Montaser, Adéla Králová, Tetsuya Terasaki, Antti Poso, Kristiina M Huttunen
Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs. Molecular pharmaceutics 20 (2) (2023)
Thanigaimalai Pillaiyar, Monika Wozniak, Dayana Abboud, Alexander Rasch, Aenne-Dorothea Liebing, Antti Poso, Thales Kronenberger, Claudia Stäubert, Stefan A Laufer, Julien Hanson
Development of Ligands for the Super Conserved Orphan G Protein-Coupled Receptor GPR27 with Improved Efficacy and Potency. Journal of medicinal chemistry (2023)
Teodor Dimitrov, Athina Anastasia Moschopoulou, Lennart Seidel, Thales Kronenberger, Mark Kudolo, Antti Poso, Christian Geibel, Pascal Wölffing, Daniel Dauch, Lars Zender, Dieter Schollmeyer, Jürgen Bajorath, Michael Forster, Stefan A Laufer
Design and Optimization of Novel Benzimidazole- and Imidazo[4,5- b ]pyridine-Based ATM Kinase Inhibitors with Subnanomolar Activities. Journal of medicinal chemistry (2023)
Thanigaimalai Pillaiyar, Philipp Flury, Nadine Krüger, Haixia Su, Laura Schäkel, Elany Barbosa da Silva, Olga Eppler, Thales Kronenberger, Tianqing Nie, Stephanie Luedtke, Cheila Rocha, Katharina Sylvester, Marvin R I Petry, James H McKerrow, Antti Poso, Stefan Pöhlmann, Michael Gütschow, Anthony J O'Donoghue, Yechun Xu, Christa Elisabeth Müller, Stefan A Laufer
Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure-Activity Relationships, Antiviral Activity, and X-ray Structure Determination. Journal of medicinal chemistry 65 (13) (2022)
Arun Kumar Tonduru, Santosh Kumar Adla, Kristiina M Huttunen, Thales Kronenberger, Antti Poso
Comparative Modelling of Organic Anion Transporting Polypeptides: Structural Insights and Comparison of Binding Modes. Molecules (Basel, Switzerland) 27 (23) (2022)
Milla Kurki, Antti Poso, Piia Bartos, Markus S Miettinen
Structure of POPC Lipid Bilayers in OPLS3e Force Field. Journal of chemical information and modeling (2022)
Lukas Imberg, Simon Platte, Catharina Erbacher, Constantin Gabriel Daniliuc, Svetlana A Kalinina, Wolfgang Dörner, Antti Poso, Uwe Karst, Dmitrii V Kalinin
Amide-functionalized 1,2,4-Triazol-5-amines as Covalent Inhibitors of Blood Coagulation Factor XIIa and Thrombin. ACS pharmacology & translational science 5 (12) (2022)
Lukas Imberg, Simon Platte, Catharina Erbacher, Constantin Gabriel Daniliuc, Svetlana A Kalinina, Wolfgang Dörner, Antti Poso, Uwe Karst, Dmitrii V Kalinin
Amide-functionalized 1,2,4-Triazol-5-amines as Covalent Inhibitors of Blood Coagulation Factor XIIa and Thrombin. ACS pharmacology & translational science 5 (12) (2022)
Arun Kumar Tonduru, Santosh Kumar Adla, Kristiina M Huttunen, Thales Kronenberger, Antti Poso
Comparative Modelling of Organic Anion Transporting Polypeptides: Structural Insights and Comparison of Binding Modes. Molecules (Basel, Switzerland) 27 (23) (2022)
Vinicius Gonçalves Maltarollo, Ekaterina Shevchenko, Igor Daniel de Miranda Lima, Elio A Cino, Glaucio Monteiro Ferreira, Antti Poso, Thales Kronenberger
Do Go Chasing Waterfalls: Enoyl Reductase (FabI) in Complex with Inhibitors Stabilizes the Tetrameric Structure and Opens Water Channels. Journal of chemical information and modeling 62 (22) (2022)
Katayun Bahrami, Juulia Järvinen, Tuomo Laitinen, Mika Reinisalo, Paavo Honkakoski, Antti Poso, Kristiina M Huttunen, Jarkko Rautio
Structural Features Affecting the Interactions and Transportability of LAT1-Targeted Phenylalanine Drug Conjugates. Molecular pharmaceutics (2022)
Alp Bayrak, Florian Mohr, Kyra Kolb, Martyna Szpakowska, Ekaterina Shevchenko, Valerie Dicenta, Anne-Katrin Rohlfing, Mark Kudolo, Tatu Pantsar, Marcel Günther, Agnieszka A Kaczor, Antti Poso, Andy Chevigné, Thanigaimalai Pillaiyar, Meinrad Gawaz, Stefan A Laufer
Discovery and Development of First-in-Class ACKR3/CXCR7 Superagonists for Platelet Degranulation Modulation. Journal of medicinal chemistry 65 (19) (2022)
Lucianna H Santos, Thales Kronenberger, Renata G Almeida, Elany B Silva, Rafael E O Rocha, Joyce C Oliveira, Luiza V Barreto, Danielle Skinner, Pavla Fajtová, Miriam A Giardini, Brendon Woodworth, Conner Bardine, André Luiz Lourenço, Charles S Craik, Antti Poso, Larissa M Podust, James H McKerrow, Jair L Siqueira-Neto, Anthony J O'Donoghue, Eufrânio N da Silva Júnior, Rafaela Salgado Ferreira
Structure-based identification of naphthoquinones and derivatives as novel inhibitors of main protease Mpro and papain-like protease PLpro of SARS-CoV-2. bioRxiv : the preprint server for biology (2022)
Lucianna H Santos, Thales Kronenberger, Renata G Almeida, Elany Barbosa da Silva, Rafael E O Rocha, Joyce C Oliveira, Luiza V Barreto, Danielle Skinner, Pavla Fajtová, Miriam A Giardini, Brendon Woodworth, Conner Bardine, André L Lourenço, Charles S Craik, Antti Poso, Larissa M Podust, James H McKerrow, Jair Lage Siqueira-Neto, Anthony J O'Donoghue, Eufrânio N da Silva Júnior, Rafaela Salgado Ferreira
Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease M pro and Papain-like Protease PL pro of SARS-CoV-2. Journal of chemical information and modeling (2022)
Arun Kumar Tonduru, Santosh Kumar Adla, Kristiina M Huttunen, Thales Kronenberger, Antti Poso
Comparative Modelling of Organic Anion Transporting Polypeptides: Structural Insights and Comparison of Binding Modes. Molecules (Basel, Switzerland) 27 (23) (2022)
Arun Kumar Tonduru, Santosh Kumar Adla, Kristiina M Huttunen, Thales Kronenberger, Antti Poso
Comparative Modelling of Organic Anion Transporting Polypeptides: Structural Insights and Comparison of Binding Modes. Molecules (Basel, Switzerland) 27 (23) (2022)
Antti Poso
The Future of Medicinal Chemistry, PROTAC, and Undruggable Drug Targets. Journal of medicinal chemistry 64 (15) (2021)
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras A Redchuk, Mariia Bogacheva, Kari Salokas, Ina Poehner, Tiina J Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa M Gawriyski, Salla Keskitalo, Maria Kristina Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
SARS-CoV-2-host proteome interactions for antiviral drug discovery. Molecular systems biology 17 (11) (2021)
Agata Zięba, Tuomo Laitinen, Jayendra Z Patel, Antti Poso, Agnieszka A Kaczor
Docking-Based 3D-QSAR Studies for 1,3,4-oxadiazol-2-one Derivatives as FAAH Inhibitors. International journal of molecular sciences 22 (11) (2021)
Roberta Tesch, Marcel Rak, Monika Raab, Lena Marie Berger, Thales Kronenberger, Andreas C Joerger, Benedict-Tilmann Berger, Ismahan Abdi, Thomas Hanke, Antti Poso, Klaus Strebhardt, Mourad Sanhaji, Stefan Knapp
Structure-Based Design of Selective Salt-Inducible Kinase Inhibitors. Journal of medicinal chemistry 64 (12) (2021)
Prasanthi Medarametla, Thales Kronenberger, Tuomo Laitinen, Antti Poso
Structural Characterization of LsrK as a Quorum Sensing Target and a Comparison between X-ray and Homology Models. Journal of chemical information and modeling 61 (3) (2021)
Michael Bitzer, Stephan Spahn, Sepideh Babaei, Marius Horger, Stephan Singer, Klaus Schulze-Osthoff, Pavlos Missios, Sergios Gatidis, Dominik Nann, Sven Mattern, Veit Scheble, Konstantin Nikolaou, Sorin Armeanu-Ebinger, Martin Schulze, Christopher Schroeder, Saskia Biskup, Janina Beha, Manfred Claassen, Kristina Ruhm, Antti Poso, Nisar P Malek
Targeting extracellular and juxtamembrane FGFR2 mutations in chemotherapy-refractory cholangiocarcinoma. NPJ precision oncology 5 (1) (2021)
Luis C Vesga, Thales Kronenberger, Arun Kumar Tonduru, Diogo Henrique Kita, Ingrid Fatima Zattoni, Cristian Camilo Bernal, Arnold R Romero Bohórquez, Stelia Carolina Mendez-Sánchez, Suresh V Ambudkar, Glaucio Valdameri, Antti Poso
Tetrahydroquinoline/4,5-Dihydroisoxazole Molecular Hybrids as Inhibitors of Breast Cancer Resistance Protein (BCRP/ABCG2). ChemMedChem 16 (17) (2021)
Santosh Kumar Adla, Arun Kumar Tonduru, Thales Kronenberger, Eva Kudova, Antti Poso, Kristiina M Huttunen
Neurosteroids: Structure-Uptake Relationships and Computational Modeling of Organic Anion Transporting Polypeptides (OATP)1A2. Molecules (Basel, Switzerland) 26 (18) (2021)
Muhammad N Ahmed, Matti Wahlsten, Jouni Kalevi Jokela, Matthias Nees, Ulf-Håkan Stenman, Danillo Oliveira Alvarenga, Tomas Strandin, Kaarina Sivonen, Antti Poso, Perttu Permi, Mikko Metsä-Ketelä, Hannu Koistinen, David Peter Fewer
Potent Inhibitor of Human Trypsins from the Aeruginosin Family of Natural Products. ACS chemical biology 16 (11) (2021)
Ramona Rudalska, Jule Harbig, Marteinn T Snaebjornsson, Sabrina Klotz, Stefan Zwirner, Liudmyla Taranets, Florian Heinzmann, Thales Kronenberger, Michael Forster, Wei Cui, Luana D'Artista, Elias Einig, Martina Hinterleitner, Werner Schmitz, Agata Dylawerska, Tae-Won Kang, Antti Poso, Mathias T Rosenfeldt, Nisar P Malek, Michael Bitzer, Stefan Laufer, Bernd J Pichler, Nikita Popov, Almut Schulze, Lars Zender, Daniel Dauch
LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer. Nature cancer 2 (2) (2021)
Thales Kronenberger, Mateus Sá Magalhães Serafim, Arun Kumar Tonduru, Vinícius Gonçalves Maltarollo, Antti Poso
Ligand Accessibility Insights to the Dengue Virus NS3-NS2B Protease Assessed by Long-Timescale Molecular Dynamics Simulations. ChemMedChem 16 (16) (2021)
Marvin Korff, Lukas Imberg, Jonas M Will, Nico Bückreiß, Svetlana A Kalinina, Benjamin M Wenzel, Gregor A Kastner, Constantin Gabriel Daniliuc, Maximilian Barth, Ruzanna A Ovsepyan, Kirill R Butov, Hans-Ulrich Humpf, Matthias Lehr, Mikhail A Panteleev, Antti Poso, Uwe Karst, Torsten Steinmetzer, Gerd Bendas, Dmitrii V Kalinin
Acylated 1H-1,2,4-Triazol-5-amines Targeting Human Coagulation Factor XIIa and Thrombin: Conventional and Microscale Synthesis, Anticoagulant Properties, and Mechanism of Action. Journal of medicinal chemistry 63 (21) (2020)
Christopher R M Asquith, Tuomo Laitinen, James M Bennett, Carrow I Wells, Jonathan M Elkins, William J Zuercher, Graham J Tizzard, Antti Poso
Design and Analysis of the 4-Anilinoquin(az)oline Kinase Inhibition Profiles of GAK/SLK/STK10 Using Quantitative Structure-Activity Relationships. ChemMedChem 15 (1) (2019)
Christopher R M Asquith, Tuomo Laitinen, Lidia S Konstantinova, Graham Tizzard, Antti Poso, Oleg A Rakitin, Regina Hofmann-Lehmann, Stephen T Hilton
Investigation of the Pentathiepin Functionality as an Inhibitor of Feline Immunodeficiency Virus (FIV) via a Potential Zinc Ejection Mechanism, as a Model for HIV Infection. ChemMedChem 14 (4) (2019)
Thales Kronenberger, Philipe de Olveira Fernandes, Isabella Drumond Franco, Antti Poso, Vinícius Gonçalves Maltarollo
Ligand- and Structure-Based Approaches of Escherichia coli FabI Inhibition by Triclosan Derivatives: From Chemical Similarity to Protein Dynamics Influence. ChemMedChem 14 (23) (2019)
Agata Zięba, Justyna Żuk, Damian Bartuzi, Dariusz Matosiuk, Antti Poso, Agnieszka A Kaczor
The Universal 3D QSAR Model for Dopamine D2 Receptor Antagonists. International journal of molecular sciences 20 (18) (2019)
Tatu Pantsar, Antti Poso
Binding Affinity via Docking: Fact and Fiction. Molecules (Basel, Switzerland) 23 (8) (2018)
Tatu Pantsar, Sami Rissanen, Daniel Dauch, Tuomo Laitinen, Ilpo Vattulainen, Antti Poso
Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling. PLoS computational biology 14 (9) (2018)
Olli Kärkkäinen, Tomi Tuomainen, Ville Mikael Koistinen, Marjo Tuomainen, Jukka Leppänen, Tuomo Laitinen, Marko Lehtonen, Jaana Rysä, Seppo Auriola, Antti Poso, Pasi Tavi, Kati Hanhineva
Whole grain intake associated molecule 5-aminovaleric acid betaine decreases β-oxidation of fatty acids in mouse cardiomyocytes. Scientific reports 8 (1) (2018)
Prasanthi Medarametla, Viviana Gatta, Tommi Kajander, Tuomo Laitinen, Päivi Tammela, Antti Poso
Structure-Based Virtual Screening of LsrK Kinase Inhibitors to Target Quorum Sensing. ChemMedChem 13 (22) (2018)

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Antti Poso