Kyle W Sloop (K W Sloop)

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 13

Top Topics

Roux En Y Gastric Bypass

Structural Basis

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Science advances

The Journal of biological chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Kimberley El, Jonathan D Douros, Francis S Willard, Aaron Novikoff, Ashot Sargsyan, Diego Perez-Tilve, David B Wainscott, Bin Yang, Alex Chen, Donald Wothe, Callum Coupland, Matthias H Tschöp, Brian Finan, David A D'Alessio, Kyle W Sloop, Timo Dirk Müller, Jonathan E Campbell
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets. Nature metabolism (2023)
Erick Spears, Jade E Stanley, Matthew Shou, Linlin Yin, Xuan Li, Chunhua Dai, Amber M Bradley, Katelyn Sellick, Greg Poffenberger, Katie C Coate, Shristi Shrestha, Regina Jenkins, Kyle W Sloop, Keith T Wilson, Alan D Attie, Mark P Keller, Wenbiao Chen, Simeon I Taylor, E Danielle Dean
Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2. bioRxiv : the preprint server for biology (2023)
Ricardo J Samms, Richard Cosgrove, Brandy M Snider, Ellen C Furber, Brian A Droz, Daniel A Briere, James Dunbar, Mridula Dogra, Jorge Alsina-Fernandez, Tito Borner, Bart C De Jonghe, Matthew R Hayes, Tamer Coskun, Kyle W Sloop, Paul J Emmerson, Minrong Ai
GIPR Agonism Inhibits PYY-Induced Nausea-Like Behavior. Diabetes 71 (7) (2022)
Marlena M Holter, Daryl J Phuong, Isaac Lee, Mridusmita Saikia, Lisa Weikert, Samantha Fountain, Elizabeth T Anderson, Qin Fu, Sheng Zhang, Kyle W Sloop, Bethany P Cummings
14-3-3-zeta mediates GLP-1 receptor agonist action to alter α cell proglucagon processing. Science advances 8 (29) (2022)
Bingfa Sun, Francis S Willard, Dan Feng, Jorge Alsina-Fernandez, Qi Chen, Michal Vieth, Joseph D Ho, Aaron D Showalter, Cynthia Stutsman, Liyun Ding, Todd M Suter, James D Dunbar, John W Carpenter, Faiz Ahmad Mohammed, Eitaro Aihara, Robert A Brown, Ana B Bueno, Paul J Emmerson, Julie S Moyers, Tong Sun Kobilka, Matthew P Coghlan, Brian K Kobilka, Kyle W Sloop
Structural determinants of dual incretin receptor agonism by tirzepatide. Proceedings of the National Academy of Sciences of the United States of America 119 (13) (2022)
Kimberley El, Sarah M Gray, M E Capozzi, E R Knuth, E Jin, B Svendsen, A Clifford, J L Brown, S E Encisco, B M Chazotte, Kyle W Sloop, Derek J Nunez, Matthew J Merrins, David A D'Alessio, Jonathan E Campbell
GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cells. Science advances 7 (11) (2021)
Francis S Willard, David B Wainscott, Aaron D Showalter, Cynthia Stutsman, Wenzhen Ma, Guemalli R Cardona, Richard W Zink, Christopher M Corkins, Qi Chen, Nathan Yumibe, Javier Agejas, Graham R Cumming, José Miguel Minguez, Alma Jiménez, Ana I Mateo, Ana M Castaño, Daniel A Briere, Kyle W Sloop, Ana B Bueno
Discovery of an Orally Efficacious Positive Allosteric Modulator of the Glucagon-like Peptide-1 Receptor. Journal of medicinal chemistry 64 (6) (2021)
Megan E Capozzi, Reilly W Coch, Jepchumba Koech, Inna I Astapova, Jacob B Wait, Sara E Encisco, Jonathan D Douros, Kimberly El, Brian Finan, Kyle W Sloop, Mark A Herman, David A D'Alessio, Jonathan E Campbell
The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition. Diabetes 69 (5) (2020)
Takahiro Kawai, Bingfa Sun, Hitoshi Yoshino, Dan Feng, Yoshiyuki Suzuki, Masanori Fukazawa, Shunsuke Nagao, David B Wainscott, Aaron D Showalter, Brian A Droz, Tong Sun Kobilka, Matthew P Coghlan, Francis S Willard, Yoshiki Kawabe, Brian K Kobilka, Kyle W Sloop
Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist. Proceedings of the National Academy of Sciences of the United States of America 117 (47) (2020)
Ana B Bueno, Bingfa Sun, Francis S Willard, Dan Feng, Joseph D Ho, David B Wainscott, Aaron D Showalter, Michal Vieth, Qi Chen, Cynthia Stutsman, Betty Chau, James Ficorilli, Francisco J Agejas, Graham R Cumming, Alma Jiménez, Isabel Rojo, Tong Sun Kobilka, Brian K Kobilka, Kyle W Sloop
Structural insights into probe-dependent positive allosterism of the GLP-1 receptor. Nature chemical biology 16 (10) (2020)
Yanqing Zhang, Keshab R Parajuli, Genevieve E Fava, Rajesh Gupta, Weiwei Xu, Lauren U Nguyen, Anadil F Zakaria, Vivian A Fonseca, Hongjun Wang, Franck Mauvais-Jarvis, Kyle W Sloop, Hongju Wu
GLP-1 Receptor in Pancreatic α-Cells Regulates Glucagon Secretion in a Glucose-Dependent Bidirectional Manner. Diabetes 68 (1) (2018)
Daniel A Briere, Ana B Bueno, Ellen J Gunn, M Dodson Michael, Kyle W Sloop
Mechanisms to Elevate Endogenous GLP-1 Beyond Injectable GLP-1 Analogs and Metabolic Surgery. Diabetes 67 (2) (2017)
Ana B Bueno, Aaron D Showalter, David B Wainscott, Cynthia Stutsman, Aranzazu Marín, James Ficorilli, Over Cabrera, Francis S Willard, Kyle W Sloop
Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles. The Journal of biological chemistry 291 (20) (2016)