Brian K Kobilka (Brian Kobilka)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 82

Top Venues

Nature

Science (New York, N.Y.)

Nature communications

Nature chemical biology

Stanford University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Stanford University Dec 01 1989

United States

Professor :: Molecular and Cellular Physiology

Publications

Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature (2024)
Evan S O'Brien, Vipin Ashok Rangari, Amal El Daibani, Shainnel O Eans, Haylee R Hammond, Elizabeth White, Haoqing Wang, Yuki Shiimura, Kaavya Krishna Kumar, Qianru Jiang, Kevin Appourchaux, Weijiao Huang, Chensong Zhang, Brandon J Kennedy, Jesper M Mathiesen, Tao Che, Jay P McLaughlin, Susruta Majumdar, Brian K Kobilka
A µ-opioid receptor modulator that works cooperatively with naloxone. Nature 631 (8021) (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature (2024)
Kaavya Krishna Kumar, Haoqing Wang, Chris Habrian, Naomi R Latorraca, Jun Xu, Evan S O'Brien, Chensong Zhang, Elizabeth Montabana, Antoine Koehl, Susan Marqusee, Ehud Y Isacoff, Brian K Kobilka
Stepwise activation of a metabotropic glutamate receptor. Nature (2024)
Kaavya Krishna Kumar, Haoqing Wang, Chris Habrian, Naomi R Latorraca, Jun Xu, Evan S O'Brien, Chensong Zhang, Elizabeth Montabana, Antoine Koehl, Susan Marqusee, Ehud Y Isacoff, Brian K Kobilka
Author Correction: Stepwise activation of a metabotropic glutamate receptor. Nature (2024)
Makaía M Papasergi-Scott, Guillermo Pérez Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K Kobilka, Peter W Hildebrand, Georgios Skiniotis
Time-resolved cryo-EM of G-protein activation by a GPCR. Nature 629 (8014) (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature 629 (8011) (2024)
Evan S O'Brien, Vipin Ashok Rangari, Amal El Daibani, Shainnel O Eans, Haylee R Hammond, Elizabeth White, Haoqing Wang, Yuki Shiimura, Kaavya Krishna Kumar, Qianru Jiang, Kevin Appourchaux, Weijiao Huang, Chensong Zhang, Brandon J Kennedy, Jesper M Mathiesen, Tao Che, Jay P McLaughlin, Susruta Majumdar, Brian K Kobilka
A µ-opioid receptor modulator that works cooperatively with naloxone. Nature 631 (8021) (2024)
Evan S O'Brien, Vipin Ashok Rangari, Amal El Daibani, Shainnel O Eans, Haylee R Hammond, Elizabeth White, Haoqing Wang, Yuki Shiimura, Kaavya Krishna Kumar, Qianru Jiang, Kevin Appourchaux, Weijiao Huang, Chensong Zhang, Brandon J Kennedy, Jesper M Mathiesen, Tao Che, Jay P McLaughlin, Susruta Majumdar, Brian K Kobilka
A µ-opioid receptor modulator that works cooperatively with naloxone. Nature (2024)
Hossein Batebi, Guillermo Pérez Hernández, Sabrina N Rahman, Baoliang Lan, Antje Kamprad, Mingyu Shi, David Speck, Johanna K S Tiemann, Ramon Guixà-Gonzaléz, Franziska Reinhardt, Peter F Stadler, Makaía M Papasergi-Scott, Georgios Skiniotis, Patrick Scheerer, Brian K Kobilka, Jesper M Mathiesen, Xiangyu Liu, Peter W Hildebrand
Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor. Nature structural & molecular biology (2024)
Makaía M Papasergi-Scott, Guillermo Pérez Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K Kobilka, Peter W Hildebrand, Georgios Skiniotis
Time-resolved cryo-EM of G-protein activation by a GPCR. Nature (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature 629 (8011) (2024)
Makaía M Papasergi-Scott, Guillermo Pérez Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K Kobilka, Peter W Hildebrand, Georgios Skiniotis
Time-resolved cryo-EM of G-protein activation by a GPCR. Nature (2024)
Makaía M Papasergi-Scott, Guillermo Pérez Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K Kobilka, Peter W Hildebrand, Georgios Skiniotis
Time-resolved cryo-EM of G-protein activation by a GPCR. Nature (2024)
Evan S O'Brien, Vipin Ashok Rangari, Amal El Daibani, Shainnel O Eans, Haylee R Hammond, Elizabeth White, Haoqing Wang, Yuki Shiimura, Kaavya Krishna Kumar, Qianru Jiang, Kevin Appourchaux, Weijiao Huang, Chensong Zhang, Brandon J Kennedy, Jesper M Mathiesen, Tao Che, Jay P McLaughlin, Susruta Majumdar, Brian K Kobilka
A µ-opioid receptor modulator that works cooperatively with naloxone. Nature (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature 629 (8011) (2024)
Kaavya Krishna Kumar, Haoqing Wang, Chris Habrian, Naomi R Latorraca, Jun Xu, Evan S O'Brien, Chensong Zhang, Elizabeth Montabana, Antoine Koehl, Susan Marqusee, Ehud Y Isacoff, Brian K Kobilka
Stepwise activation of a metabotropic glutamate receptor. Nature (2024)
Kaavya Krishna Kumar, Haoqing Wang, Chris Habrian, Naomi R Latorraca, Jun Xu, Evan S O'Brien, Chensong Zhang, Elizabeth Montabana, Antoine Koehl, Susan Marqusee, Ehud Y Isacoff, Brian K Kobilka
Stepwise activation of a metabotropic glutamate receptor. Nature (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature 629 (8011) (2024)
Makaía M Papasergi-Scott, Guillermo Pérez Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K Kobilka, Peter W Hildebrand, Georgios Skiniotis
Time-resolved cryo-EM of G-protein activation by a GPCR. Nature 629 (8014) (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature 629 (8011) (2024)
Evan S O'Brien, Vipin Ashok Rangari, Amal El Daibani, Shainnel O Eans, Haylee R Hammond, Elizabeth White, Haoqing Wang, Yuki Shiimura, Kaavya Krishna Kumar, Qianru Jiang, Kevin Appourchaux, Weijiao Huang, Chensong Zhang, Brandon J Kennedy, Jesper M Mathiesen, Tao Che, Jay P McLaughlin, Susruta Majumdar, Brian K Kobilka
A µ-opioid receptor modulator that works cooperatively with naloxone. Nature 631 (8021) (2024)
Makaía M Papasergi-Scott, Guillermo Pérez Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K Kobilka, Peter W Hildebrand, Georgios Skiniotis
Time-resolved cryo-EM of G-protein activation by a GPCR. Nature (2024)
Makaía M Papasergi-Scott, Guillermo Pérez Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K Kobilka, Peter W Hildebrand, Georgios Skiniotis
Time-resolved cryo-EM of G-protein activation by a GPCR. Nature 629 (8014) (2024)
Kaavya Krishna Kumar, Haoqing Wang, Chris Habrian, Naomi R Latorraca, Jun Xu, Evan S O'Brien, Chensong Zhang, Elizabeth Montabana, Antoine Koehl, Susan Marqusee, Ehud Y Isacoff, Brian K Kobilka
Stepwise activation of a metabotropic glutamate receptor. Nature 629 (8013) (2024)
Kaavya Krishna Kumar, Haoqing Wang, Chris Habrian, Naomi R Latorraca, Jun Xu, Evan S O'Brien, Chensong Zhang, Elizabeth Montabana, Antoine Koehl, Susan Marqusee, Ehud Y Isacoff, Brian K Kobilka
Stepwise activation of a metabotropic glutamate receptor. Nature 629 (8013) (2024)
Kaavya Krishna Kumar, Haoqing Wang, Chris Habrian, Naomi R Latorraca, Jun Xu, Evan S O'Brien, Chensong Zhang, Elizabeth Montabana, Antoine Koehl, Susan Marqusee, Ehud Y Isacoff, Brian K Kobilka
Author Correction: Stepwise activation of a metabotropic glutamate receptor. Nature (2024)
Evan S O'Brien, Vipin Ashok Rangari, Amal El Daibani, Shainnel O Eans, Haylee R Hammond, Elizabeth White, Haoqing Wang, Yuki Shiimura, Kaavya Krishna Kumar, Qianru Jiang, Kevin Appourchaux, Weijiao Huang, Chensong Zhang, Brandon J Kennedy, Jesper M Mathiesen, Tao Che, Jay P McLaughlin, Susruta Majumdar, Brian K Kobilka
A µ-opioid receptor modulator that works cooperatively with naloxone. Nature 631 (8021) (2024)
Kaavya Krishna Kumar, Haoqing Wang, Chris Habrian, Naomi R Latorraca, Jun Xu, Evan S O'Brien, Chensong Zhang, Elizabeth Montabana, Antoine Koehl, Susan Marqusee, Ehud Y Isacoff, Brian K Kobilka
Stepwise activation of a metabotropic glutamate receptor. Nature 629 (8013) (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy. bioRxiv : the preprint server for biology (2023)
Franziska Marie Heydenreich, Maria Marti-Solano, Manbir Sandhu, Brian K Kobilka, Michel Bouvier, M Madan Babu
Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.) 382 (6677) (2023)
Jie Heng, Yunfei Hu, Guillermo Pérez Hernández, Asuka Inoue, Jiawei Zhao, Xiuyan Ma, Xiaoou Sun, Kouki Kawakami, Tatsuya Ikuta, Jienv Ding, Yujie Yang, Lujia Zhang, Sijia Peng, Xiaogang Niu, Hongwei Li, Ramon Guixà-Gonzaléz, Changwen Jin, Peter W Hildebrand, Chunlai Chen, Brian K Kobilka
Function and dynamics of the intrinsically disordered carboxyl terminus of β2 adrenergic receptor. Nature communications 14 (1) (2023)
Jun Xu, Qinggong Wang, Harald Hübner, Yunfei Hu, Xiaogang Niu, Haoqing Wang, Shoji Maeda, Asuka Inoue, Yuyong Tao, Peter Gmeiner, Yang Du, Changwen Jin, Brian K Kobilka
Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature communications 14 (1) (2023)
Makaía M Papasergi-Scott, Guillermo Pérez Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay Burak Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K Kobilka, Peter W Hildebrand, Georgios Skiniotis
Time-resolved cryo-EM of G protein activation by a GPCR. bioRxiv : the preprint server for biology (2023)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy. bioRxiv : the preprint server for biology (2023)
Jun Xu, Qinggong Wang, Harald Hübner, Yunfei Hu, Xiaogang Niu, Haoqing Wang, Shoji Maeda, Asuka Inoue, Yuyong Tao, Peter Gmeiner, Yang Du, Changwen Jin, Brian K Kobilka
Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature communications 14 (1) (2023)
Xinyu Xu, Jeremy Shonberg, Jonas Kaindl, Mary J Clark, Anne Stößel, Luis Maul, Daniel Mayer, Harald Hübner, Kunio Hirata, A J Venkatakrishnan, Ron O Dror, Brian K Kobilka, Roger K Sunahara, Xiangyu Liu, Peter Gmeiner
Constrained catecholamines gain β 2 AR selectivity through allosteric effects on pocket dynamics. Nature communications 14 (1) (2023)
Yosuke Toyoda, Angqi Zhu, Fang Kong, Sisi Shan, Jiawei Zhao, Nan Wang, Xiaoou Sun, Linqi Zhang, Chuangye Yan, Brian K Kobilka, Xiangyu Liu
Structural basis of α 1A -adrenergic receptor activation and recognition by an extracellular nanobody. Nature communications 14 (1) (2023)
Xinyu Xu, Jeremy Shonberg, Jonas Kaindl, Mary J Clark, Anne Stößel, Luis Maul, Daniel Mayer, Harald Hübner, Kunio Hirata, A J Venkatakrishnan, Ron O Dror, Brian K Kobilka, Roger K Sunahara, Xiangyu Liu, Peter Gmeiner
Author Correction: Constrained catecholamines gain β 2 AR selectivity through allosteric effects on pocket dynamics. Nature communications 14 (1) (2023)
Franziska Marie Heydenreich, Maria Marti-Solano, Manbir Sandhu, Brian K Kobilka, Michel Bouvier, M Madan Babu
Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.) 382 (6677) (2023)
Kaavya Krishna Kumar, Michael J Robertson, Elina Thadhani, Haoqing Wang, Carl-Mikael Suomivuori, Alexander S Powers, Lipin Ji, Spyros P Nikas, Ron O Dror, Asuka Inoue, Alexandros Makriyannis, Georgios Skiniotis, Brian K Kobilka
Structural basis for activation of CB1 by an endocannabinoid analog. Nature communications 14 (1) (2023)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy. bioRxiv : the preprint server for biology (2023)
Franziska Marie Heydenreich, Maria Marti-Solano, Manbir Sandhu, Brian K Kobilka, Michel Bouvier, M Madan Babu
Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.) 382 (6677) (2023)
Franziska Marie Heydenreich, Maria Marti-Solano, Manbir Sandhu, Brian K Kobilka, Michel Bouvier, M Madan Babu
Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.) 382 (6677) (2023)
Franziska Marie Heydenreich, Maria Marti-Solano, Manbir Sandhu, Brian K Kobilka, Michel Bouvier, M Madan Babu
Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.) 382 (6677) (2023)
Franziska Marie Heydenreich, Maria Marti-Solano, Manbir Sandhu, Brian K Kobilka, Michel Bouvier, M Madan Babu
Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.) 382 (6677) (2023)
Jun Xu, Qinggong Wang, Harald Hübner, Yunfei Hu, Xiaogang Niu, Haoqing Wang, Shoji Maeda, Asuka Inoue, Yuyong Tao, Peter Gmeiner, Yang Du, Changwen Jin, Brian K Kobilka
Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature communications 14 (1) (2023)
Kaavya Krishna Kumar, Michael J Robertson, Elina Thadhani, Haoqing Wang, Carl-Mikael Suomivuori, Alexander S Powers, Lipin Ji, Spyros P Nikas, Ron O Dror, Asuka Inoue, Alexandros Makriyannis, Georgios Skiniotis, Brian K Kobilka
Structural basis for activation of CB1 by an endocannabinoid analog. Nature communications 14 (1) (2023)
Franziska Marie Heydenreich, Maria Marti-Solano, Manbir Sandhu, Brian K Kobilka, Michel Bouvier, M Madan Babu
Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.) 382 (6677) (2023)
Franziska Marie Heydenreich, Maria Marti-Solano, Manbir Sandhu, Brian K Kobilka, Michel Bouvier, M Madan Babu
Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.) 382 (6677) (2023)
Kaavya Krishna Kumar, Michael J Robertson, Elina Thadhani, Haoqing Wang, Carl-Mikael Suomivuori, Alexander S Powers, Lipin Ji, Spyros P Nikas, Ron O Dror, Asuka Inoue, Alexandros Makriyannis, Georgios Skiniotis, Brian K Kobilka
Structural basis for activation of CB1 by an endocannabinoid analog. Nature communications 14 (1) (2023)
Franziska Marie Heydenreich, Maria Marti-Solano, Manbir Sandhu, Brian K Kobilka, Michel Bouvier, M Madan Babu
Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.) 382 (6677) (2023)
Qianhui Qu, Weijiao Huang, Deniz Aydin, Joseph M Paggi, Alpay B Seven, Haoqing Wang, Soumen Chakraborty, Tao Che, Jeffrey F DiBerto, Michael J Robertson, Asuka Inoue, Carl-Mikael Suomivuori, Bryan L Roth, Susruta Majumdar, Ron O Dror, Brian K Kobilka, Georgios Skiniotis
Insights into distinct signaling profiles of the µOR activated by diverse agonists. Nature chemical biology (2022)
Naotaka Tsutsumi, Shoji Maeda, Qianhui Qu, Martin Vögele, Kevin M Jude, Carl-Mikael Suomivuori, Ouliana Panova, Deepa Waghray, Hideaki E Kato, Andrew Velasco, Ron O Dror, Georgios Skiniotis, Brian K Kobilka, K Christopher Garcia
Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins. Science advances 8 (3) (2022)
Abdelfattah Faouzi, Haoqing Wang, Saheem A Zaidi, Jeffrey F DiBerto, Tao Che, Qianhui Qu, Michael J Robertson, Manish K Madasu, Amal El Daibani, Balazs R Varga, Tiffany Zhang, Claudia Ruiz, Shan Liu, Jin Xu, Kevin Appourchaux, Samuel T Slocum, Shainnel O Eans, Michael D Cameron, Ream Al-Hasani, Ying Xian Pan, Bryan L Roth, Jay P McLaughlin, Georgios Skiniotis, Vsevolod Katritch, Brian K Kobilka, Susruta Majumdar
Structure-based design of bitopic ligands for the µ-opioid receptor. Nature (2022)
Tetiana Serdiuk, Moutusi Manna, Cheng Zhang, Stefania A Mari, Waldemar Kulig, Kristyna Pluhackova, Brian K Kobilka, Ilpo Vattulainen, Daniel J Müller
A cholesterol analog stabilizes the human β 2 -adrenergic receptor nonlinearly with temperature. Science signaling 15 (737) (2022)
Bingfa Sun, Francis S Willard, Dan Feng, Jorge Alsina-Fernandez, Qi Chen, Michal Vieth, Joseph D Ho, Aaron D Showalter, Cynthia Stutsman, Liyun Ding, Todd M Suter, James D Dunbar, John W Carpenter, Faiz Ahmad Mohammed, Eitaro Aihara, Robert A Brown, Ana B Bueno, Paul J Emmerson, Julie S Moyers, Tong Sun Kobilka, Matthew P Coghlan, Brian K Kobilka, Kyle W Sloop
Structural determinants of dual incretin receptor agonism by tirzepatide. Proceedings of the National Academy of Sciences of the United States of America 119 (13) (2022)
Paul J Utz, Mukesh K Jain, Vivian G Cheung, Brian K Kobilka, Robert J Lefkowitz, Tadataka Yamada, Victor J Dzau
Translating science to medicine: The case for physician-scientists. Science translational medicine 14 (632) (2022)
Bingfa Sun, Dan Feng, Matthew Ling-Hon Chu, Inbar Fish, Silvia Lovera, Zara A Sands, Alastair D G Lawson, Anne Valade, Martyn Wood, Tom Ceska, Tong Sun Kobilka, Florence Lebon, Brian K Kobilka
Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist. Nature communications 12 (1) (2021)
Alpay B Seven, Ximena Barros-Álvarez, Marine de Lapeyrière, Makaía M Papasergi-Scott, Michael J Robertson, Chensong Zhang, Robert M Nwokonko, Yang Gao, Justin G Meyerowitz, Jean-Philippe Rocher, Dominik Schelshorn, Brian K Kobilka, Jesper Mosolff Mathiesen, Georgios Skiniotis
G-protein activation by a metabotropic glutamate receptor. Nature 595 (7867) (2021)
Daopeng Yuan, Zhongmin Liu, Jonas Kaindl, Shoji Maeda, Jiawei Zhao, Xiaoou Sun, Jun Xu, Peter Gmeiner, Hong-Wei Wang, Brian K Kobilka
Activation of the α2B adrenoceptor by the sedative sympatholytic dexmedetomidine. Nature chemical biology 16 (5) (2020)
Takahiro Kawai, Bingfa Sun, Hitoshi Yoshino, Dan Feng, Yoshiyuki Suzuki, Masanori Fukazawa, Shunsuke Nagao, David B Wainscott, Aaron D Showalter, Brian A Droz, Tong Sun Kobilka, Matthew P Coghlan, Francis S Willard, Yoshiki Kawabe, Brian K Kobilka, Kyle W Sloop
Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist. Proceedings of the National Academy of Sciences of the United States of America 117 (47) (2020)
Daniel Hilger, Kaavya Krishna Kumar, Hongli Hu, Mie Fabricius Pedersen, Evan S O'Brien, Lise Giehm, Christine Jennings, Gözde Eskici, Asuka Inoue, Michael T Lerch, Jesper Mosolff Mathiesen, Georgios Skiniotis, Brian K Kobilka
Structural insights into differences in G protein activation by family A and family B GPCRs. Science (New York, N.Y.) 369 (6503) (2020)
Ana B Bueno, Bingfa Sun, Francis S Willard, Dan Feng, Joseph D Ho, David B Wainscott, Aaron D Showalter, Michal Vieth, Qi Chen, Cynthia Stutsman, Betty Chau, James Ficorilli, Francisco J Agejas, Graham R Cumming, Alma Jiménez, Isabel Rojo, Tong Sun Kobilka, Brian K Kobilka, Kyle W Sloop
Structural insights into probe-dependent positive allosterism of the GLP-1 receptor. Nature chemical biology 16 (10) (2020)
Michael T Lerch, Rachel Ann Matt, Matthieu Masureel, Matthias Elgeti, Kaavya Krishna Kumar, Daniel Hilger, Bryon Foys, Brian K Kobilka, Wayne L Hubbell
Viewing rare conformations of the β2 adrenergic receptor with pressure-resolved DEER spectroscopy. Proceedings of the National Academy of Sciences of the United States of America 117 (50) (2020)
Shoji Maeda, Jun Xu, Francois Marie N Kadji, Mary J Clark, Jiawei Zhao, Naotaka Tsutsumi, Junken Aoki, Roger K Sunahara, Asuka Inoue, K Christopher Garcia, Brian K Kobilka
Structure and selectivity engineering of the M1 muscarinic receptor toxin complex. Science (New York, N.Y.) 369 (6500) (2020)
Xiangyu Liu, Jonas Kaindl, Magdalena Korczynska, Anne Stößel, Daniela Dengler, Markus Stanek, Harald Hübner, Mary J Clark, Jake Mahoney, Rachel Ann Matt, Xinyu Xu, Kunio Hirata, Brian K Shoichet, Roger K Sunahara, Brian K Kobilka, Peter Gmeiner
An allosteric modulator binds to a conformational hub in the β2 adrenergic receptor. Nature chemical biology 16 (7) (2020)
Shoji Maeda, Qianhui Qu, Michael J Robertson, Georgios Skiniotis, Brian K Kobilka
Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes. Science (New York, N.Y.) 364 (6440) (2019)
Muhammad Ehsan, Yang Du, Iago Molist, Alpay Burak Seven, Parameswaran Hariharan, Jonas Sigurd Mortensen, Lubna Ghani, Claus J Løland, Georgios Skiniotis, Lan Guan, Bernadette Byrne, Brian K Kobilka, Pil Seok Chae
Vitamin E-based glycoside amphiphiles for membrane protein structural studies. Organic & biomolecular chemistry 16 (14) (2019)
Muhammad Ehsan, Ashwani Kumar, Jonas Sigurd Mortensen, Yang Du, Parameswaran Hariharan, Kaavya K Kumar, Betty Ha, Bernadette Byrne, Lan Guan, Brian K Kobilka, Claus J Løland, Pil Seok Chae
Self-Assembly Behaviors of a Penta-Phenylene Maltoside and Its Application for Membrane Protein Study. Chemistry, an Asian journal 14 (11) (2019)
Xiangyu Liu, Ali Masoudi, Alem W Kahsai, Li-Yin Huang, Biswaranjan Pani, Dean P Staus, Paul Jaehoon Shim, Kunio Hirata, Rishabh K Simhal, Allison M Schwalb, Paula K Rambarat, Seungkirl Ahn, Robert J Lefkowitz, Brian K Kobilka
Mechanism of β2AR regulation by an intracellular positive allosteric modulator. Science (New York, N.Y.) 364 (6447) (2019)
Manabendra Das, Yang Du, Jonas Sigurd Mortensen, Hyoung Eun Bae, Bernadette Byrne, Claus J Løland, Brian K Kobilka, Pil Seok Chae
An Engineered Lithocholate-Based Facial Amphiphile Stabilizes Membrane Proteins: Assessing the Impact of Detergent Customizability on Protein Stability. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (39) (2018)
Muhammad Ehsan, Manabendra Das, Valerie Stern, Yang Du, Jonas Sigurd Mortensen, Parameswaran Hariharan, Bernadette Byrne, Claus J Løland, Brian K Kobilka, Lan Guan, Pil Seok Chae
Steroid-Based Amphiphiles for Membrane Protein Study: The Importance of Alkyl Spacers for Protein Stability. Chembiochem : a European journal of chemical biology 19 (13) (2018)
Manabendra Das, Yang Du, Jonas Sigurd Mortensen, Parameswaran Hariharan, Hyun Sung Lee, Bernadette Byrne, Claus J Løland, Lan Guan, Brian K Kobilka, Pil Seok Chae
Rationally Engineered Tandem Facial Amphiphiles for Improved Membrane Protein Stabilization Efficacy. Chembiochem : a European journal of chemical biology 19 (20) (2018)
Hyoung Eun Bae, Yang Du, Parameswaran Hariharan, Jonas Sigurd Mortensen, Kaavya K Kumar, Betty Ha, Manabendra Das, Hyun Sung Lee, Claus J Løland, Lan Guan, Brian K Kobilka, Pil Seok Chae
Asymmetric maltose neopentyl glycol amphiphiles for a membrane protein study: effect of detergent asymmetricity on protein stability. Chemical science 10 (4) (2018)
Hazrat Hussain, Yang Du, Elena B Tikhonova, Jonas Sigurd Mortensen, Orquidea M de Castro Ribeiro, Claudia Santillan, Manabendra Das, Muhammad Ehsan, Claus J Løland, Lan Guan, Brian K Kobilka, Bernadette Byrne, Pil Seok Chae
Resorcinarene-Based Facial Glycosides: Implication of Detergent Flexibility on Membrane-Protein Stability. Chemistry (Weinheim an der Bergstrasse, Germany) 23 (28) (2017)
Aiman Sadaf, Yang Du, Claudia Santillan, Jonas Sigurd Mortensen, Iago Molist, Alpay Burak Seven, Parameswaran Hariharan, Georgios Skiniotis, Claus J Løland, Brian K Kobilka, Lan Guan, Bernadette Byrne, Pil Seok Chae
Dendronic trimaltoside amphiphiles (DTMs) for membrane protein study. Chemical science 8 (12) (2017)
Manabendra Das, Yang Du, Jonas Sigurd Mortensen, Orquidea M de Castro Ribeiro, Parameswaran Hariharan, Lan Guan, Claus J Løland, Brian K Kobilka, Bernadette Byrne, Pil Seok Chae
Butane-1,2,3,4-tetraol-based amphiphilic stereoisomers for membrane protein study: importance of chirality in the linker region. Chemical science 8 (2) (2016)
Hazrat Hussain, Yang Du, Nicola J Scull, Jonas Sigurd Mortensen, Jeffrey Tarrasch, Hyoung Eun Bae, Claus J Løland, Bernadette Byrne, Brian K Kobilka, Pil Seok Chae
Accessible Mannitol-Based Amphiphiles (MNAs) for Membrane Protein Solubilisation and Stabilisation. Chemistry (Weinheim an der Bergstrasse, Germany) 22 (21) (2016)
Kyung-Ho Cho, Parameswaran Hariharan, Jonas Sigurd Mortensen, Yang Du, Anne Kathrine Nielsen, Bernadette Byrne, Brian K Kobilka, Claus J Løland, Lan Guan, Pil Seok Chae
Isomeric Detergent Comparison for Membrane Protein Stability: Importance of Inter-Alkyl-Chain Distance and Alkyl Chain Length. Chembiochem : a European journal of chemical biology 17 (24) (2016)
Kyung-Ho Cho, Orquidea M de Castro Ribeiro, Yang Du, Elena B Tikhonova, Jonas Sigurd Mortensen, Kelsey Markham, Parameswaran Hariharan, Claus J Løland, Lan Guan, Brian K Kobilka, Bernadette Byrne, Pil Seok Chae
Mesitylene-Cored Glucoside Amphiphiles (MGAs) for Membrane Protein Studies: Importance of Alkyl Chain Density in Detergent Efficacy. Chemistry (Weinheim an der Bergstrasse, Germany) 22 (52) (2016)

Brian K Kobilka.css-eqlu8i{font-size:small;padding-left:4px;} (Brian Kobilka)

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Brian K Kobilka (Brian Kobilka)