Lak Shin Jeong

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 30

Top Topics

Hepatitis C Virus

Network Analysis

Structure Activity Relationship

Top Venues

Journal of medicinal chemistry

Organic letters

The Journal of organic chemistry

Pharmaceuticals (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Gibae Kim, Dnyandev B Jarhad, Grim Lee, Gyudong Kim, Xiyan Hou, Jinha Yu, Chang Soo Lee, Eugene Warnick, Zhan-Guo Gao, Sang Yeop Ahn, Dongik Kwak, Kichul Park, Summer Dabin Lee, Tae-Uk Park, So-Young Jung, Jong Hyun Lee, Jong-Ryoul Choi, Myeongjoong Kim, Donghyun Kim, Bongtae Kim, Kenneth A Jacobson, Lak Shin Jeong
Structural Modification and Biological Evaluation of 2,8-Disubstituted Adenine and Its Nucleosides as A 2A Adenosine Receptor Antagonists: Exploring the Roles of Ribose at Adenosine Receptors. Journal of medicinal chemistry 67 (12) (2024)
Gibae Kim, Xiyan Hou, Woong Sub Byun, Gyudong Kim, Dnyandev B Jarhad, Grim Lee, Young Eum Hyun, Jinha Yu, Chang Soo Lee, Shuhao Qu, Eugene Warnick, Zhan-Guo Gao, Ji Yong Kim, Seunghee Ji, Hyunwoo Shin, Jong-Ryoul Choi, Kenneth A Jacobson, Hyuk Woo Lee, Sang-Kook Lee, Lak Shin Jeong
Correction to "Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A 2A /A 3 Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity". Journal of medicinal chemistry 67 (3) (2024)
Gibae Kim, Dnyandev B Jarhad, Grim Lee, Gyudong Kim, Xiyan Hou, Jinha Yu, Chang Soo Lee, Eugene Warnick, Zhan-Guo Gao, Sang Yeop Ahn, Dongik Kwak, Kichul Park, Summer Dabin Lee, Tae-Uk Park, So-Young Jung, Jong Hyun Lee, Jong-Ryoul Choi, Myeongjoong Kim, Donghyun Kim, Bongtae Kim, Kenneth A Jacobson, Lak Shin Jeong
Structural Modification and Biological Evaluation of 2,8-Disubstituted Adenine and Its Nucleosides as A 2A Adenosine Receptor Antagonists: Exploring the Roles of Ribose at Adenosine Receptors. Journal of medicinal chemistry 67 (12) (2024)
Gibae Kim, Dnyandev B Jarhad, Grim Lee, Gyudong Kim, Xiyan Hou, Jinha Yu, Chang Soo Lee, Eugene Warnick, Zhan-Guo Gao, Sang Yeop Ahn, Dongik Kwak, Kichul Park, Summer Dabin Lee, Tae-Uk Park, So-Young Jung, Jong Hyun Lee, Jong-Ryoul Choi, Myeongjoong Kim, Donghyun Kim, Bongtae Kim, Kenneth A Jacobson, Lak Shin Jeong
Structural Modification and Biological Evaluation of 2,8-Disubstituted Adenine and Its Nucleosides as A 2A Adenosine Receptor Antagonists: Exploring the Roles of Ribose at Adenosine Receptors. Journal of medicinal chemistry (2024)
Gibae Kim, Xiyan Hou, Woong Sub Byun, Gyudong Kim, Dnyandev B Jarhad, Grim Lee, Young Eum Hyun, Jinha Yu, Chang Soo Lee, Shuhao Qu, Eugene Warnick, Zhan-Guo Gao, Ji Yong Kim, Seunghee Ji, Hyunwoo Shin, Jong-Ryoul Choi, Kenneth A Jacobson, Hyuk Woo Lee, Sang-Kook Lee, Lak Shin Jeong
Correction to "Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A 2A /A 3 Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity". Journal of medicinal chemistry (2024)
Gibae Kim, Dnyandev B Jarhad, Grim Lee, Gyudong Kim, Xiyan Hou, Jinha Yu, Chang Soo Lee, Eugene Warnick, Zhan-Guo Gao, Sang Yeop Ahn, Dongik Kwak, Kichul Park, Summer Dabin Lee, Tae-Uk Park, So-Young Jung, Jong Hyun Lee, Jong-Ryoul Choi, Myeongjoong Kim, Donghyun Kim, Bongtae Kim, Kenneth A Jacobson, Lak Shin Jeong
Structural Modification and Biological Evaluation of 2,8-Disubstituted Adenine and Its Nucleosides as A 2A Adenosine Receptor Antagonists: Exploring the Roles of Ribose at Adenosine Receptors. Journal of medicinal chemistry 67 (12) (2024)
Gibae Kim, Xiyan Hou, Woong Sub Byun, Gyudong Kim, Dnyandev B Jarhad, Grim Lee, Young Eum Hyun, Jinha Yu, Chang Soo Lee, Shuhao Qu, Eugene Warnick, Zhan-Guo Gao, Ji Yong Kim, Seunghee Ji, Hyunwoo Shin, Jong-Ryoul Choi, Kenneth A Jacobson, Hyuk Woo Lee, Sang-Kook Lee, Lak Shin Jeong
Correction to "Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A 2A /A 3 Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity". Journal of medicinal chemistry 67 (3) (2024)
Gibae Kim, Dnyandev B Jarhad, Grim Lee, Gyudong Kim, Xiyan Hou, Jinha Yu, Chang Soo Lee, Eugene Warnick, Zhan-Guo Gao, Sang Yeop Ahn, Dongik Kwak, Kichul Park, Summer Dabin Lee, Tae-Uk Park, So-Young Jung, Jong Hyun Lee, Jong-Ryoul Choi, Myeongjoong Kim, Donghyun Kim, Bongtae Kim, Kenneth A Jacobson, Lak Shin Jeong
Structural Modification and Biological Evaluation of 2,8-Disubstituted Adenine and Its Nucleosides as A 2A Adenosine Receptor Antagonists: Exploring the Roles of Ribose at Adenosine Receptors. Journal of medicinal chemistry 67 (12) (2024)
Gibae Kim, Xiyan Hou, Woong Sub Byun, Gyudong Kim, Dnyandev B Jarhad, Grim Lee, Young Eum Hyun, Jinha Yu, Chang Soo Lee, Shuhao Qu, Eugene Warnick, Zhan-Guo Gao, Ji Yong Kim, Seunghee Ji, Hyunwoo Shin, Jong-Ryoul Choi, Kenneth A Jacobson, Hyuk Woo Lee, Sang-Kook Lee, Lak Shin Jeong
Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A 2A /A 3 Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity. Journal of medicinal chemistry (2023)
Eun-Ji Kwon, Karishma K Mashelkar, Juhee Seo, Yoon-Ze Shin, Kisu Sung, Sung Chul Jang, Sang Won Cheon, Haeseung Lee, Hyuk Woo Lee, Gyudong Kim, Byung Woo Han, Sang-Kook Lee, Lak Shin Jeong, Hyuk-Jin Cha
In Silico Discovery of 5'-Modified 7-Deoxy-7-ethynyl-4'-thioadenosine as a HASPIN Inhibitor and Its Synergistic Anticancer Effect with the PLK1 Inhibitor. ACS central science 9 (6) (2023)
Kisu Sung, Vikas R Aswar, Jiyoon Song, Dnyandev B Jarhad, Lak Shin Jeong
Stereoselective Approach for the Synthesis of Diverse 1'-Modified Carbanucleosides. Organic letters (2023)
Young Eum Hyun, Seungchan An, Minjae Kim, In Guk Park, Sanghee Yoon, Hafiz Muhammad Ahmad Javaid, Thi Ngoc Lan Vu, Gyudong Kim, Hongseok Choi, Hyuk Woo Lee, Minsoo Noh, Joo Young Huh, Sun Choi, Hong-Rae Kim, Lak Shin Jeong
Structure-Activity Relationships of Truncated 1'-Homologated Carbaadenosine Derivatives as New PPARγ/δ Ligands: A Study on Sugar Puckering Affecting Binding to PPARs. Journal of medicinal chemistry (2023)
Young Eum Hyun, Dnyandev B Jarhad, Minjae Kim, Ayeon Yang, Gyudong Kim, Hong-Rae Kim, Lak Shin Jeong
Synthesis of Enantiomerically Pure Pyrimidine Ribonucleosides Locked in the South Conformation. Organic letters 24 (50) (2022)
Anna Shiriaeva, Daejin Park, Gyudong Kim, Yoonji Lee, Xiyan Hou, Dnyandev B Jarhad, Gibae Kim, Jinha Yu, Young Eum Hyun, Woomi Kim, Zhan-Guo Gao, Kenneth A Jacobson, Gye Won Han, Raymond C Stevens, Lak Shin Jeong, Sun Choi, Vadim Cherezov
GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A 2A Adenosine Receptor. Journal of medicinal chemistry 65 (17) (2022)
Mai Nguyen, Seungchan An, Yen Nguyen, Young Eum Hyun, Hongseok Choi, Linh Pham, Jung-Ae Kim, Minsoo Noh, Gyudong Kim, Lak Shin Jeong
Design, Synthesis, and Biological Activity of l-1'-Homologated Adenosine Derivatives. ACS medicinal chemistry letters 13 (7) (2022)
Young Sup Shin, Jun Young Lee, Sangeun Jeon, Jung-Eun Cho, Subeen Myung, Min Seong Jang, Seungtaek Kim, Jong Hwan Song, Hyoung Rae Kim, Hyeung-Geun Park, Lak Shin Jeong, Chul Min Park
Optimization of 2-Aminoquinazolin-4-(3 H )-one Derivatives as Potent Inhibitors of SARS-CoV-2: Improved Synthesis and Pharmacokinetic Properties. Pharmaceuticals (Basel, Switzerland) 15 (7) (2022)
Young Eum Hyun, Dnyandev B Jarhad, Minjae Kim, Ayeon Yang, Gyudong Kim, Hong-Rae Kim, Lak Shin Jeong
Synthesis of Enantiomerically Pure Pyrimidine Ribonucleosides Locked in the South Conformation. Organic letters (2022)
Young Eum Hyun, Dnyandev B Jarhad, Minjae Kim, Ayeon Yang, Gyudong Kim, Hong-Rae Kim, Lak Shin Jeong
Synthesis of Enantiomerically Pure Pyrimidine Ribonucleosides Locked in the South Conformation. Organic letters 24 (50) (2022)
Young Eum Hyun, Hong-Rae Kim, Lak Shin Jeong
Stereoselective Synthesis of (S)- and (N)-Cyclopropyl-Fused Carbocyclic Nucleosides Using Stereoselective Cyclopropanation. The Journal of organic chemistry 86 (14) (2021)
Karishma K Mashelkar, Woong Sub Byun, Hyejin Ko, Kisu Sung, Sushil K Tripathi, Seungchan An, Yun A Yum, Jee Youn Kwon, Minjae Kim, Gibae Kim, Eun-Ji Kwon, Hyuk Woo Lee, Minsoo Noh, Sang-Kook Lee, Lak Shin Jeong
Discovery of a Novel Template, 7-Substituted 7-Deaza-4'-Thioadenosine Derivatives as Multi-Kinase Inhibitors. Pharmaceuticals (Basel, Switzerland) 14 (12) (2021)
Yoonji Lee, Xiyan Hou, Jin Hee Lee, Akshata Nayak, Varughese Alexander, Pankaz K Sharma, Hyerim Chang, Khai Phan, Zhan-Guo Gao, Kenneth A Jacobson, Sun Choi, Lak Shin Jeong
Subtle Chemical Changes Cross the Boundary between Agonist and Antagonist: New A3 Adenosine Receptor Homology Models and Structural Network Analysis Can Predict This Boundary. Journal of medicinal chemistry 64 (17) (2021)
Seungchan An, Gyudong Kim, Hyun Jin Kim, Sungjin Ahn, Hyun Young Kim, Hyejin Ko, Young Eum Hyun, Mai Nguyen, Juri Jeong, Zijing Liu, Jinhe Han, Hongseok Choi, Jinha Yu, Ji Won Kim, Hyuk Woo Lee, Kenneth A Jacobson, Won Jea Cho, Young-Mi Kim, Keon Wook Kang, Minsoo Noh, Lak Shin Jeong
Discovery and Structure-Activity Relationships of Novel Template, Truncated 1'-Homologated Adenosine Derivatives as Pure Dual PPARγ/δ Modulators. Journal of medicinal chemistry 63 (24) (2020)
Mi Jeong Heo, Sung Hyun Kang, Yun Seok Kim, Jung Min Lee, Jinha Yu, Hong-Rae Kim, Hyesol Lim, Kyoung Mee Kim, Joohee Jung, Lak Shin Jeong, Aree Moon, Sang Geon Kim
UBC12-mediated SREBP-1 neddylation worsens metastatic tumor prognosis. International journal of cancer 147 (9) (2020)
Hyejin Lee, Dnyandev B Jarhad, Jinha Yu, Choongho Lee, Lak Shin Jeong
Asymmetric Synthesis of 2'-C-Methyl-4'-selenonucleosides as Anti-Hepatitis C Virus Agents. The Journal of organic chemistry 84 (22) (2019)
Ji-Seong Yoon, Gyudong Kim, Dnyandev B Jarhad, Hong-Rae Kim, Young-Sup Shin, Shuhao Qu, Pramod K Sahu, Hea Ok Kim, Hyuk Woo Lee, Su Bin Wang, Yun Jeong Kong, Tong-Shin Chang, Natacha S Ogando, Kristina Kovacikova, Eric J Snijder, Clara C Posthuma, Martijn J van Hemert, Lak Shin Jeong
Design, Synthesis, and Anti-RNA Virus Activity of 6'-Fluorinated-Aristeromycin Analogues. Journal of medicinal chemistry 62 (13) (2019)
Dnyandev B Jarhad, Karishma K Mashelkar, Hong-Rae Kim, Minsoo Noh, Lak Shin Jeong
Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics. Journal of medicinal chemistry 61 (22) (2018)
Gyudong Kim, Ji-Seong Yoon, Dnyandev B Jarhad, Young Sup Shin, Mahesh S Majik, Varughese A Mulamoottil, Xiyan Hou, Shuhao Qu, Jiyong Park, Mu-Hyun Baik, Lak Shin Jeong
Asymmetric Synthesis of (-)-6'-β-Fluoro-aristeromycin via Stereoselective Electrophilic Fluorination. Organic letters 19 (21) (2018)
Hye Sook Min, Jin Joo Cha, Kitae Kim, Jung Eun Kim, Jung Yeon Ghee, Hyunwook Kim, Ji Eun Lee, Jee-Young Han, Lak Shin Jeong, Dae Ryong Cha, Young Sun Kang
Renoprotective Effects of a Highly Selective A3 Adenosine Receptor Antagonist in a Mouse Model of Adriamycin-induced Nephropathy. Journal of Korean medical science 31 (9) (2017)
Jinha Yu, Long Xuan Zhao, Jongmi Park, Hyuk Woo Lee, Pramod K Sahu, Minghua Cui, Steven M Moss, Eva Hammes, Eugene Warnick, Zhan-Guo Gao, Minsoo Noh, Sun Choi, Hee-Chul Ahn, Jungwon Choi, Kenneth A Jacobson, Lak Shin Jeong
N6-Substituted 5'-N-Methylcarbamoyl-4'-selenoadenosines as Potent and Selective A3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation. Journal of medicinal chemistry 60 (8) (2017)
Jinha Yu, Seyeon Ahn, Hee Jin Kim, Moonyoung Lee, Sungjin Ahn, Jungmin Kim, Sun Hee Jin, Eunyoung Lee, Gyudong Kim, Jae Hoon Cheong, Kenneth A Jacobson, Lak Shin Jeong, Minsoo Noh
Polypharmacology of N6-(3-Iodobenzyl)adenosine-5'-N-methyluronamide (IB-MECA) and Related A3 Adenosine Receptor Ligands: Peroxisome Proliferator Activated Receptor (PPAR) γ Partial Agonist and PPARδ Antagonist Activity Suggests Their Antidiabetic Potential. Journal of medicinal chemistry 60 (17) (2017)