Leonard M Neckers (Len Neckers)

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 11

Top Topics

Renal Cell Carcinoma

Radical Prostatectomy

Prostate Cancer

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Scientific reports

Clinical cancer research : an official journal of the American Association for Cancer Research

This page only lists publications with an associated author ORCID identifier.

Publications

Frank J Echtenkamp, Ryo Ishida, Genesis M Rivera-Marquez, Marisa Maisiak, Oleta T Johnson, Jonathan H Shrimp, Arnav Sinha, Stephen John Ralph, Ian Nisbet, Murali Krishna Cherukuri, Jason E Gestwicki, Leonard M Neckers
Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer. PNAS nexus 2 (4) (2023)
Grace B McKay-Corkum, Victor J Collins, Choh Yeung, Takeshi Ito, Sameer H Issaq, David O Holland, Ksenia Vulikh, Yiping Zhang, Unsun Lee, Haiyan Lei, Arnulfo Mendoza, Jack F Shern, Marielle E Yohe, Kazutoshi Yamamoto, Kelli M Wilson, Jiuping Ji, Baktiar O Karim, Craig J Thomas, Murali C Krishna, Leonard M Neckers, Christine M Heske
Inhibition of NAD+-dependent metabolic processes induces cellular necrosis and tumor regression in rhabdomyosarcoma models. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Frank J Echtenkamp, Ryo Ishida, Genesis M Rivera-Marquez, Marisa Maisiak, Oleta T Johnson, Jonathan H Shrimp, Arnav Sinha, Stephen John Ralph, Ian Nisbet, Murali Krishna Cherukuri, Jason E Gestwicki, Leonard M Neckers
Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer. PNAS nexus 2 (4) (2023)
Frank J Echtenkamp, Ryo Ishida, Genesis M Rivera-Marquez, Marisa Maisiak, Oleta T Johnson, Jonathan H Shrimp, Arnav Sinha, Stephen John Ralph, Ian Nisbet, Murali Krishna Cherukuri, Jason E Gestwicki, Leonard M Neckers
Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer. PNAS nexus 2 (4) (2023)
Gabriela Chiosis, Chander S Digwal, Jane B Trepel, Leonard M Neckers
Structural and functional complexity of HSP90 in cellular homeostasis and disease. Nature reviews. Molecular cell biology (2023)
Frank J Echtenkamp, Ryo Ishida, Genesis M Rivera-Marquez, Marisa Maisiak, Oleta T Johnson, Jonathan H Shrimp, Arnav Sinha, Stephen John Ralph, Ian Nisbet, Murali Krishna Cherukuri, Jason E Gestwicki, Leonard M Neckers
Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer. PNAS nexus 2 (4) (2023)
Anderson R Frank, Vicky Li, Spencer D Shelton, Jiwoong Kim, Gordon M Stott, Leonard M Neckers, Yang Xie, Noelle S Williams, Prashant Mishra, David G McFadden
Mitochondrial-encoded complex I impairment induces a targetable dependency on aerobic fermentation in Hurthle cell carcinoma of the thyroid. Cancer discovery (2023)
Dalton Hermans, Sanjivan Gautam, Juan Carlos García-Cañaveras, Daniel Gromer, Suman Mitra, Rosanne Spolski, Peng Li, Stephen Christensen, Rosa Nguyen, Jian-Xin Lin, Jangsuk Oh, Ning Du, Sharon Veenbergen, Jessica Fioravanti, Risa Ebina-Shibuya, Christopher K E Bleck, Leonard M Neckers, Joshua D Rabinowitz, Luca Gattinoni, Warren J Leonard
Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8+ T cell stemness and antitumor immunity. Proceedings of the National Academy of Sciences of the United States of America 117 (11) (2020)
Wanping Xu, Kristin Beebe, Juan D Chavez, Marta Boysen, YinYing Lu, Abbey D Zuehlke, Dimitra Keramisanou, Jane B Trepel, Chrisostomos Prodromou, Matthias P Mayer, James E Bruce, Ioannis Gelis, Leonard M Neckers
Hsp90 middle domain phosphorylation initiates a complex conformational program to recruit the ATPase-stimulating cochaperone Aha1. Nature communications 10 (1) (2019)
Carole Sourbier, Christopher J Ricketts, Pei-Jyun Liao, Shingo Matsumoto, Darmood Wei, Martin Lang, Reema Railkar, Youfeng Yang, Ming-Hui Wei, Piyush Agarwal, Murali Krishna, James B Mitchell, Jane B Trepel, Leonard M Neckers, W Marston Linehan
Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-Myc. Scientific reports 9 (1) (2019)
Abbey D Zuehlke, Michael A Moses, Leonard M Neckers
Heat shock protein 90: its inhibition and function. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 373 (1738) (2018)