Mario Juan Borgnia (Mario J Borgnia)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 37

Top Topics

Structural Basis

Electron Microscopy

Arabidopsis Thaliana

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

Nature structural & molecular biology

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Erica J Washington, Ye Zhou, Allen L Hsu, Matthew Petrovich, Jennifer L Tenor, Dena L Toffaletti, Ziqiang Guan, John R Perfect, Mario Juan Borgnia, Alberto Bartesaghi, Richard G Brennan
Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : A target for antifungals. Proceedings of the National Academy of Sciences of the United States of America 121 (32) (2024)
Chen Qiu, Sarah L Crittenden, Brian H Carrick, Lucas B Dillard, Stephany J Costa Dos Santos, Venkata P Dandey, Robert C Dutcher, Elizabeth G Viverette, Robert N Wine, Jennifer Woodworth, Zachary T Campbell, Marvin Wickens, Mario Juan Borgnia, Judith Kimble, Traci M Tanaka Hall
A higher order PUF complex is central to regulation of C. elegans germline stem cells. bioRxiv : the preprint server for biology (2024)
Nicholas J Wright, Feng Zhang, Yang Suo, Lingyang Kong, Ying Yin, Justin G Fedor, Kedar Sharma, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Antiviral drug recognition and elevator-type transport motions of CNT3. Nature chemical biology 20 (9) (2024)
Nicholas J Wright, Feng Zhang, Yang Suo, Lingyang Kong, Ying Yin, Justin G Fedor, Kedar Sharma, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Antiviral drug recognition and elevator-type transport motions of CNT3. Nature chemical biology 20 (9) (2024)
Cassandra K Hayne, Kevin John U Butay, Zachary D Stewart, Juno M Krahn, Lalith Perera, Jason G Williams, Robert M Petrovitch, Leesa J Deterding, A Gregory Matera, Mario Juan Borgnia, Robin E Stanley
Author Correction: Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex. Nature structural & molecular biology (2024)
Erica J Washington, Ye Zhou, Allen L Hsu, Matthew Petrovich, Jennifer L Tenor, Dena L Toffaletti, Ziqiang Guan, John R Perfect, Mario Juan Borgnia, Alberto Bartesaghi, Richard G Brennan
Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : A target for antifungals. Proceedings of the National Academy of Sciences of the United States of America 121 (32) (2024)
Chen Qiu, Sarah L Crittenden, Brian H Carrick, Lucas B Dillard, Stephany J Costa Dos Santos, Venkata P Dandey, Robert C Dutcher, Elizabeth G Viverette, Robert N Wine, Jennifer Woodworth, Zachary T Campbell, Marvin Wickens, Mario Juan Borgnia, Judith Kimble, Traci M Tanaka Hall
A higher order PUF complex is central to regulation of C. elegans germline stem cells. bioRxiv : the preprint server for biology (2024)
Erica J Washington, Ye Zhou, Allen L Hsu, Matthew Petrovich, Jennifer L Tenor, Dena L Toffaletti, Ziqiang Guan, John R Perfect, Mario Juan Borgnia, Alberto Bartesaghi, Richard G Brennan
Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : A target for antifungals. Proceedings of the National Academy of Sciences of the United States of America 121 (32) (2024)
Nicholas J Wright, Feng Zhang, Yang Suo, Lingyang Kong, Ying Yin, Justin G Fedor, Kedar Sharma, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Antiviral drug recognition and elevator-type transport motions of CNT3. Nature chemical biology (2024)
Erica J Washington, Ye Zhou, Allen L Hsu, Matthew Petrovich, Jennifer L Tenor, Dena L Toffaletti, Ziqiang Guan, John R Perfect, Mario Juan Borgnia, Alberto Bartesaghi, Richard G Brennan
Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : A target for antifungals. Proceedings of the National Academy of Sciences of the United States of America 121 (32) (2024)
Shivesh Kumar, Yan Wang, Ye Zhou, Lucas Dillard, Fay-Wei Li, Carly A Sciandra, Ning Sui, Rodolfo Zentella, Emily Zahn, Jeffrey Shabanowitz, Donald F Hunt, Mario Juan Borgnia, Alberto Bartesaghi, Tai-Ping Sun, Pei Zhou
Structure and dynamics of the Arabidopsis O-fucosyltransferase SPINDLY. Nature communications 14 (1) (2023)
Erica J Washington, Ye Zhou, Allen L Hsu, Matthew Petrovich, Mario Juan Borgnia, Alberto Bartesaghi, Richard G Brennan
Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : a target for novel antifungals. bioRxiv : the preprint server for biology (2023)
Yang Suo, Nicholas J Wright, Hugo Guterres, Justin G Fedor, Kevin John U Butay, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2. Nature structural & molecular biology (2023)
Cassandra K Hayne, Kevin John U Butay, Zachary D Stewart, Juno M Krahn, Lalith Perera, Jason G Williams, Robert M Petrovitch, Leesa J Deterding, A Gregory Matera, Mario Juan Borgnia, Robin E Stanley
Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex. Nature structural & molecular biology (2023)
Shivesh Kumar, Yan Wang, Ye Zhou, Lucas Dillard, Fay-Wei Li, Carly A Sciandra, Ning Sui, Rodolfo Zentella, Emily Zahn, Jeffrey Shabanowitz, Donald F Hunt, Mario Juan Borgnia, Alberto Bartesaghi, Tai-Ping Sun, Pei Zhou
Structure and dynamics of the Arabidopsis O-fucosyltransferase SPINDLY. Nature communications 14 (1) (2023)
Shivesh Kumar, Yan Wang, Ye Zhou, Lucas Dillard, Fay-Wei Li, Carly A Sciandra, Ning Sui, Rodolfo Zentella, Emily Zahn, Jeffrey Shabanowitz, Donald F Hunt, Mario Juan Borgnia, Alberto Bartesaghi, Tai-Ping Sun, Pei Zhou
Structure and dynamics of the Arabidopsis O-fucosyltransferase SPINDLY. Nature communications 14 (1) (2023)
Yang Suo, Nicholas J Wright, Hugo Guterres, Justin G Fedor, Kevin John U Butay, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Molecular basis of polyspecific drug binding and transport by OCT1 and OCT2. bioRxiv : the preprint server for biology (2023)
Jessica Hong, Hyung Joon Kwon, Raul Cachau, Catherine Z Chen, Kevin John Butay, Zhijian Duan, Dan Li, Hua Ren, Tianyuzhou Liang, Jianghai Zhu, Venkata P Dandey, Negin P Martin, Dominic Esposito, Uriel Ortega-Rodriguez, Miao Xu, Mario Juan Borgnia, Hang Xie, Mitchell Ho
Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants. Proceedings of the National Academy of Sciences of the United States of America 119 (18) (2022)
Ying Yin, Feng Zhang, Shasha Feng, Kevin John U Butay, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2 . Science (New York, N.Y.) 378 (6616) (2022)
Brady A Travis, Jared V Peck, Raul Salinas, Brandon Dopkins, Nicholas Lent, Viet D Nguyen, Mario Juan Borgnia, Richard G Brennan, Maria A Schumacher
Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nature communications 13 (1) (2022)
Soumen Saha, Samagya Banskota, Jianqiao Liu, Nikita Zakharov, Michael J Dzuricky, Xinghai Li, Ping Fan, Sonal Deshpande, Ivan Spasojevic, Kedar Sharma, Mario Juan Borgnia, Jeffrey L Schaal, Ashutosh Raman, Sarah Kim, Jayanta Bhattacharyya, Ashutosh Chilkoti
Genetically Engineered Nanoparticles of Asymmetric Triblock Polypeptide with a Platinum(IV) Cargo Outperforms a Platinum(II) Analog and Free Drug in a Murine Cancer Model. Nano letters 22 (14) (2022)
Jacob Gordon, Fleur L Chapus, Elizabeth G Viverette, Jason G Williams, Leesa J Deterding, Juno M Krahn, Mario Juan Borgnia, Joseph Rodriguez, Alan John Warren, Robin E Stanley
Cryo-EM reveals the architecture of the PELP1-WDR18 molecular scaffold. Nature communications 13 (1) (2022)
Bradley P Klemm, Deepa Singh, Cassandra E Smith, Allen L Hsu, Lucas B Dillard, Juno M Krahn, Robert E London, Geoffrey A Mueller, Mario Juan Borgnia, Roel M Schaaper
Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase. Proceedings of the National Academy of Sciences of the United States of America 119 (37) (2022)
Amanda A Riccio, Jonathan Bouvette, Lalith Perera, Matthew J Longley, Juno M Krahn, Jason G Williams, Robert C Dutcher, Mario Juan Borgnia, William C Copeland
Structural insight and characterization of human Twinkle helicase in mitochondrial disease. Proceedings of the National Academy of Sciences of the United States of America 119 (32) (2022)
Jonathan Bouvette, Qinwen Huang, Amanda A Riccio, William C Copeland, Alberto Bartesaghi, Mario Juan Borgnia
Automated systematic evaluation of cryo-EM specimens with SmartScope. eLife 11 (2022)
Anvesh K R Dasari, Lucas Dillard, Sujung Yi, Elizabeth Viverette, Alimohammad Hojjatian, Urmi Sengupta, Rakez Kayed, Kenneth A Taylor, Mario Juan Borgnia, Kwang Hun Lim
Untwisted α-Synuclein Filaments Formed in the Presence of Lipid Vesicles. Biochemistry 61 (17) (2022)
Shivesh Kumar, Raul Zavaliev, Qinglin Wu, Ye Zhou, Jie Cheng, Lucas Dillard, Jordan Powers, John Withers, Jinshi Zhao, Ziqiang Guan, Mario Juan Borgnia, Alberto Bartesaghi, Xinnian Dong, Pei Zhou
Structural basis of NPR1 in activating plant immunity. Nature 605 (7910) (2022)
Jonathan Bouvette, Hsuan-Fu Liu, Xiaochen Du, Ye Zhou, Andrew P Sikkema, Juliana da Fonseca Rezende E Mello, Bradley P Klemm, Rick Huang, Roel M Schaaper, Mario Juan Borgnia, Alberto Bartesaghi
Beam image-shift accelerated data acquisition for near-atomic resolution single-particle cryo-electron tomography. Nature communications 12 (1) (2021)
Do Hoon Kwon, Feng Zhang, Yang Suo, Jonathan Bouvette, Mario Juan Borgnia, Seok-Yong Lee
Heat-dependent opening of TRPV1 in the presence of capsaicin. Nature structural & molecular biology 28 (7) (2021)
Monica C Pillon, Meredith N Frazier, Lucas B Dillard, Jason G Williams, Seda Kocaman, Juno M Krahn, Lalith Perera, Cassandra K Hayne, Jacob Gordon, Zachary D Stewart, Mack Sobhany, Leesa J Deterding, Allen L Hsu, Venkata P Dandey, Mario Juan Borgnia, Robin E Stanley
Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics. Nature communications 12 (1) (2021)
Ye Zhou, Panagiotis L Kastritis, Shannon E Dougherty, Jonathan Bouvette, Allen L Hsu, Laura Burbaum, Shyamal Mosalaganti, Stefan Pfeffer, Wim J H Hagen, Friedrich Förster, Mario Juan Borgnia, Christine Vogel, Martin Beck, Alberto Bartesaghi, Gustavo M Silva
Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. Proceedings of the National Academy of Sciences of the United States of America 117 (36) (2020)
Kevin O Saunders, Kevin Wiehe, Ming Tian, Priyamvada Acharya, Todd Bradley, S Munir Alam, Eden P Go, Richard M Scearce, Laura L Sutherland, Rory C Henderson, Allen L Hsu, Mario Juan Borgnia, Haiyan Chen, Xiaozhi Lu, Nelson R Wu, Brian Watts, Chuancang Jiang, David Easterhoff, Hwei-Ling Cheng, Kelly McGovern, Peyton Waddicor, Aimee Chapdelaine-Williams, Amanda Eaton, Jinsong Zhang, R Wes Rountree, Laurent Verkoczy, Mark A Tomai, Mark G Lewis, Heather R Desaire, Robert J Edwards, Derek W Cain, Mattia Bonsignori, David C Montefiori, Frederick W Alt, Barton F Haynes
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science (New York, N.Y.) 366 (6470) (2020)
Kathryn H Gunn, Benjamin S Roberts, Fengbin Wang, Joshua D Strauss, Mario Juan Borgnia, Edward H Egelman, Saskia B Neher
The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage. Proceedings of the National Academy of Sciences of the United States of America 117 (19) (2020)
Celia C LaBranche, Rory Henderson, Allen L Hsu, Shay Behrens, Xuejun Chen, Tongqing Zhou, Kevin Wiehe, Kevin O Saunders, S Munir Alam, Mattia Bonsignori, Mario Juan Borgnia, Quentin J Sattentau, Amanda Eaton, Kelli Greene, Hongmei Gao, Hua-Xin Liao, Wilton B Williams, James Peacock, Haili Tang, Lautaro G Perez, Robert J Edwards, Thomas B Kepler, Bette T Korber, Peter D Kwong, John R Mascola, Priyamvada Acharya, Barton F Haynes, David C Montefiori
Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies. PLoS pathogens 15 (9) (2019)
Lejla Zubcevic, Allen L Hsu, Mario Juan Borgnia, Seok-Yong Lee
Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes. eLife 8 (2019)
Ying Yin, Son C Le, Allen L Hsu, Mario Juan Borgnia, Huanghe Yang, Seok-Yong Lee
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel. Science (New York, N.Y.) 363 (6430) (2019)
Lejla Zubcevic, William F Borschel, Allen L Hsu, Mario Juan Borgnia, Seok-Yong Lee
Regulatory switch at the cytoplasmic interface controls TRPV channel gating. eLife 8 (2019)