Xuejun Chen

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 24

Top Topics

Men Who Have Sex With Men

Saccharomyces Cerevisiae

Top Venues

Nature communications

Science translational medicine

Nature medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Jason Gorman, Crystal Sao-Fong Cheung, Zhijian Duan, Li Ou, Maple Wang, Xuejun Chen, Cheng Cheng, Andrea Biju, Yaping Sun, Pengfei Wang, Yongping Yang, Baoshan Zhang, Jeffrey C Boyington, Tatsiana Bylund, Sam Charaf, Steven J Chen, Haijuan Du, Amy R Henry, Tracy Liu, Edward K Sarfo, Chaim A Schramm, Chen-Hsiang Shen, Tyler Stephens, I-Ting Teng, John-Paul Todd, Yaroslav Tsybovsky, Raffaello Verardi, Danyi Wang, Shuishu Wang, Zhantong Wang, Cheng-Yan Zheng, Tongqing Zhou, Daniel C Douek, John R Mascola, David D Ho, Mitchell Ho, Peter D Kwong
Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability. Nature communications 15 (1) (2024)
Joana Dias, Giulia Fabozzi, Slim Fourati, Xuejun Chen, Cuiping Liu, David R Ambrozak, Amy Ransier, Farida Laboune, Jianfei Hu, Wei Shi, Kylie March, Anna A Maximova, Stephen D Schmidt, Jakob Samsel, Chloe Adrienna Talana, Keenan Ernste, Sung Hee Ko, Margaret E Lucas, Pierce E Radecki, Kristin L Boswell, Yoshiaki Nishimura, John-Paul Todd, Malcolm A Martin, Constantinos Petrovas, Eli A Boritz, Nicole A Doria-Rose, Daniel C Douek, Rafick-Pierre Sekaly, Jeffrey D Lifson, Mangaiarkarasi Asokan, Lucio Gama, John R Mascola, Amarendra Pegu, Richard A Koup
Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIV AD8-EO infection. Nature communications 15 (1) (2024)
Amarendra Pegu, Sarah E Lovelace, Megan E DeMouth, Michelle D Cully, Daniel J Morris, Yingying Li, Keyun Wang, Stephen D Schmidt, Misook Choe, Cuiping Liu, Xuejun Chen, Elise G Viox, Ariana P Rowshan, Justin D Taft, Baoshan Zhang, Kai Xu, Hongying Duan, Li Ou, John-Paul M Todd, Rui Kong, Hui Li, George M Shaw, Nicole A Doria-Rose, Peter D Kwong, Richard A Koup, John R Mascola
Antibodies targeting the fusion peptide on the HIV envelope provide protection to rhesus macaques against mucosal SHIV challenge. Science translational medicine 16 (730) (2024)
Jason Gorman, Crystal Sao-Fong Cheung, Zhijian Duan, Li Ou, Maple Wang, Xuejun Chen, Cheng Cheng, Andrea Biju, Yaping Sun, Pengfei Wang, Yongping Yang, Baoshan Zhang, Jeffrey C Boyington, Tatsiana Bylund, Sam Charaf, Steven J Chen, Haijuan Du, Amy R Henry, Tracy Liu, Edward K Sarfo, Chaim A Schramm, Chen-Hsiang Shen, Tyler Stephens, I-Ting Teng, John-Paul Todd, Yaroslav Tsybovsky, Raffaello Verardi, Danyi Wang, Shuishu Wang, Zhantong Wang, Cheng-Yan Zheng, Tongqing Zhou, Daniel C Douek, John R Mascola, David D Ho, Mitchell Ho, Peter D Kwong
Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability. Nature communications 15 (1) (2024)
Jason Gorman, Crystal Sao-Fong Cheung, Zhijian Duan, Li Ou, Maple Wang, Xuejun Chen, Cheng Cheng, Andrea Biju, Yaping Sun, Pengfei Wang, Yongping Yang, Baoshan Zhang, Jeffrey C Boyington, Tatsiana Bylund, Sam Charaf, Steven J Chen, Haijuan Du, Amy R Henry, Tracy Liu, Edward K Sarfo, Chaim A Schramm, Chen-Hsiang Shen, Tyler Stephens, I-Ting Teng, John-Paul Todd, Yaroslav Tsybovsky, Raffaello Verardi, Danyi Wang, Shuishu Wang, Zhantong Wang, Cheng-Yan Zheng, Tongqing Zhou, Daniel C Douek, John R Mascola, David D Ho, Mitchell Ho, Peter D Kwong
Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability. Nature communications 15 (1) (2024)
Christopher A Cottrell, Xiaozhen Hu, Jeong Hyun Lee, Patrick D Skog, Sai Luo, Claudia T Flynn, Katherine R McKenney, Jonathan Hurtado, Oleksandr Kalyuzhniy, Alessia Liguori, Jordan R Willis, Elise Landais, Sebastian Rämisch, Xuejun Chen, Sabyasachi Baboo, Sunny Himansu, Jolene K Diedrich, Hongying Duan, Cheng Cheng, Torben Schiffner, Daniel L V Bader, Daniel W Kulp, Ryan Tingle, Erik Georgeson, Saman Eskandarzadeh, Nushin Alavi, Danny Lu, Troy Sincomb, Michael Kubitz, Tina-Marie Mullen, John Yates Iii, James C Paulson, John R Mascola, Frederick W Alt, Bryan Briney, Devin Sok, William R Schief
Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice. Science translational medicine 16 (748) (2024)
Joana Dias, Giulia Fabozzi, Slim Fourati, Xuejun Chen, Cuiping Liu, David R Ambrozak, Amy Ransier, Farida Laboune, Jianfei Hu, Wei Shi, Kylie March, Anna A Maximova, Stephen D Schmidt, Jakob Samsel, Chloe Adrienna Talana, Keenan Ernste, Sung Hee Ko, Margaret E Lucas, Pierce E Radecki, Kristin L Boswell, Yoshiaki Nishimura, John-Paul Todd, Malcolm A Martin, Constantinos Petrovas, Eli A Boritz, Nicole A Doria-Rose, Daniel C Douek, Rafick-Pierre Sekaly, Jeffrey D Lifson, Mangaiarkarasi Asokan, Lucio Gama, John R Mascola, Amarendra Pegu, Richard A Koup
Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIV AD8-EO infection. Nature communications 15 (1) (2024)
Christopher A Cottrell, Xiaozhen Hu, Jeong Hyun Lee, Patrick D Skog, Sai Luo, Claudia T Flynn, Katherine R McKenney, Jonathan Hurtado, Oleksandr Kalyuzhniy, Alessia Liguori, Jordan R Willis, Elise Landais, Sebastian Rämisch, Xuejun Chen, Sabyasachi Baboo, Sunny Himansu, Jolene K Diedrich, Hongying Duan, Cheng Cheng, Torben Schiffner, Daniel L V Bader, Daniel W Kulp, Ryan Tingle, Erik Georgeson, Saman Eskandarzadeh, Nushin Alavi, Danny Lu, Troy Sincomb, Michael Kubitz, Tina-Marie Mullen, John Yates Iii, James C Paulson, John R Mascola, Frederick W Alt, Bryan Briney, Devin Sok, William R Schief
Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice. Science translational medicine 16 (748) (2024)
Joana Dias, Giulia Fabozzi, Slim Fourati, Xuejun Chen, Cuiping Liu, David R Ambrozak, Amy Ransier, Farida Laboune, Jianfei Hu, Wei Shi, Kylie March, Anna A Maximova, Stephen D Schmidt, Jakob Samsel, Chloe Adrienna Talana, Keenan Ernste, Sung Hee Ko, Margaret E Lucas, Pierce E Radecki, Kristin L Boswell, Yoshiaki Nishimura, John-Paul Todd, Malcolm A Martin, Constantinos Petrovas, Eli A Boritz, Nicole A Doria-Rose, Daniel C Douek, Rafick-Pierre Sekaly, Jeffrey D Lifson, Mangaiarkarasi Asokan, Lucio Gama, John R Mascola, Amarendra Pegu, Richard A Koup
Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIV AD8-EO infection. Nature communications 15 (1) (2024)
Christopher A Cottrell, Xiaozhen Hu, Jeong Hyun Lee, Patrick D Skog, Sai Luo, Claudia T Flynn, Katherine R McKenney, Jonathan Hurtado, Oleksandr Kalyuzhniy, Alessia Liguori, Jordan R Willis, Elise Landais, Sebastian Rämisch, Xuejun Chen, Sabyasachi Baboo, Sunny Himansu, Jolene K Diedrich, Hongying Duan, Cheng Cheng, Torben Schiffner, Daniel L V Bader, Daniel W Kulp, Ryan Tingle, Erik Georgeson, Saman Eskandarzadeh, Nushin Alavi, Danny Lu, Troy Sincomb, Michael Kubitz, Tina-Marie Mullen, John Yates Iii, James C Paulson, John R Mascola, Frederick W Alt, Bryan Briney, Devin Sok, William R Schief
Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice. Science translational medicine 16 (748) (2024)
Jason Gorman, Crystal Sao-Fong Cheung, Zhijian Duan, Li Ou, Maple Wang, Xuejun Chen, Cheng Cheng, Andrea Biju, Yaping Sun, Pengfei Wang, Yongping Yang, Baoshan Zhang, Jeffrey C Boyington, Tatsiana Bylund, Sam Charaf, Steven J Chen, Haijuan Du, Amy R Henry, Tracy Liu, Edward K Sarfo, Chaim A Schramm, Chen-Hsiang Shen, Tyler Stephens, I-Ting Teng, John-Paul Todd, Yaroslav Tsybovsky, Raffaello Verardi, Danyi Wang, Shuishu Wang, Zhantong Wang, Cheng-Yan Zheng, Tongqing Zhou, Daniel C Douek, John R Mascola, David D Ho, Mitchell Ho, Peter D Kwong
Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability. Nature communications 15 (1) (2024)
Jason Gorman, Crystal Sao-Fong Cheung, Zhijian Duan, Li Ou, Maple Wang, Xuejun Chen, Cheng Cheng, Andrea Biju, Yaping Sun, Pengfei Wang, Yongping Yang, Baoshan Zhang, Jeffrey C Boyington, Tatsiana Bylund, Sam Charaf, Steven J Chen, Haijuan Du, Amy R Henry, Tracy Liu, Edward K Sarfo, Chaim A Schramm, Chen-Hsiang Shen, Tyler Stephens, I-Ting Teng, John-Paul Todd, Yaroslav Tsybovsky, Raffaello Verardi, Danyi Wang, Shuishu Wang, Zhantong Wang, Cheng-Yan Zheng, Tongqing Zhou, Daniel C Douek, John R Mascola, David D Ho, Mitchell Ho, Peter D Kwong
Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability. Nature communications 15 (1) (2024)
Christopher A Cottrell, Xiaozhen Hu, Jeong Hyun Lee, Patrick D Skog, Sai Luo, Claudia T Flynn, Katherine R McKenney, Jonathan Hurtado, Oleksandr Kalyuzhniy, Alessia Liguori, Jordan R Willis, Elise Landais, Sebastian Rämisch, Xuejun Chen, Sabyasachi Baboo, Sunny Himansu, Jolene K Diedrich, Hongying Duan, Cheng Cheng, Torben Schiffner, Daniel L V Bader, Daniel W Kulp, Ryan Tingle, Erik Georgeson, Saman Eskandarzadeh, Nushin Alavi, Danny Lu, Troy Sincomb, Michael Kubitz, Tina-Marie Mullen, John Yates Iii, James C Paulson, John R Mascola, Frederick W Alt, Bryan Briney, Devin Sok, William R Schief
Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice. Science translational medicine (2024)
Amarendra Pegu, Sarah E Lovelace, Megan E DeMouth, Michelle D Cully, Daniel J Morris, Yingying Li, Keyun Wang, Stephen D Schmidt, Misook Choe, Cuiping Liu, Xuejun Chen, Elise G Viox, Ariana P Rowshan, Justin D Taft, Baoshan Zhang, Kai Xu, Hongying Duan, Li Ou, John-Paul M Todd, Rui Kong, Hui Li, George M Shaw, Nicole A Doria-Rose, Peter D Kwong, Richard A Koup, John R Mascola
Antibodies targeting the fusion peptide on the HIV envelope provide protection to rhesus macaques against mucosal SHIV challenge. Science translational medicine 16 (730) (2024)
Jason Gorman, Crystal Sao-Fong Cheung, Zhijian Duan, Li Ou, Maple Wang, Xuejun Chen, Cheng Cheng, Andrea Biju, Yaping Sun, Pengfei Wang, Yongping Yang, Baoshan Zhang, Jeffrey C Boyington, Tatsiana Bylund, Sam Charaf, Steven J Chen, Haijuan Du, Amy R Henry, Tracy Liu, Edward K Sarfo, Chaim A Schramm, Chen-Hsiang Shen, Tyler Stephens, I-Ting Teng, John-Paul Todd, Yaroslav Tsybovsky, Raffaello Verardi, Danyi Wang, Shuishu Wang, Zhantong Wang, Cheng-Yan Zheng, Tongqing Zhou, Daniel C Douek, John R Mascola, David D Ho, Mitchell Ho, Peter D Kwong
Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability. Nature communications 15 (1) (2024)
Joseph P Casazza, Evan M Cale, Sandeep Narpala, Galina V Yamshchikov, Emily E Coates, Cynthia S Hendel, Laura Novik, LaSonji A Holman, Alicia T Widge, Preeti Apte, Ingelise Gordon, Martin R Gaudinski, Michelle Conan-Cibotti, Bob C Lin, Martha C Nason, Olga Trofymenko, Shinyi Telscher, Sarah H Plummer, Diane Wycuff, William C Adams, Janardan P Pandey, Adrian B McDermott, Mario Roederer, Avery N Sukienik, Sijy O'Dell, Jason G Gall, Britta Flach, Travis L Terry, Misook Choe, Wei Shi, Xuejun Chen, Florence Kaltovich, Kevin O Saunders, Judy A Stein, Nicole A Doria-Rose, Richard M Schwartz, Alejandro B Balazs, David Baltimore, Gary J Nabel, Richard A Koup, Barney S Graham, Julie E Ledgerwood, John R Mascola, null null
Safety and tolerability of AAV8 delivery of a broadly neutralizing antibody in adults living with HIV: a phase 1, dose-escalation trial. Nature medicine 28 (5) (2022)
Peng Zhang, Elisabeth Narayanan, Qingbo Liu, Yaroslav Tsybovsky, Kristin Boswell, Shilei Ding, Zonghui Hu, Dean Follmann, Yin Lin, Huiyi Miao, Hana Schmeisser, Denise Rogers, Samantha Falcone, Sayda M Elbashir, Vladimir Presnyak, Kapil Bahl, Madhu Prabhakaran, Xuejun Chen, Edward K Sarfo, David R Ambrozak, Rajeev Gautam, Malcom A Martin, Joanna Swerczek, Richard Herbert, Deborah Weiss, Johnathan Misamore, Giuseppe Ciaramella, Sunny Himansu, Guillaume Stewart-Jones, Adrian B McDermott, Richard A Koup, John R Mascola, Andrés Finzi, Andrea Carfi, Anthony S Fauci, Paolo Lusso
A multiclade env-gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques. Nature medicine (2021)
Jing Wen, Tracy Ordonez, Lan Wang, Di Wu, Jason Reed, John R Mascola, Xuejun Chen, Cuiping Liu, Amarendra Pegu, Jonah B Sacha, Yunfeng Lu, Nancy L Haigwood, Irvin S Y Chen
Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques. PLoS pathogens 17 (7) (2021)
Mariya B Shapiro, Tracy Cheever, Delphine C Malherbe, Shilpi Pandey, Jason Reed, Eun Sung Yang, Keyun Wang, Amarendra Pegu, Xuejun Chen, Don Siess, David Burke, Heidi Henderson, Rebecca Lewinsohn, Miranda Fischer, Jeffrey J Stanton, Michael K Axthelm, Christoph Kahl, Byung Park, Anne D Lewis, Jonah B Sacha, John R Mascola, Ann J Hessell, Nancy L Haigwood
Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity. Nature communications 11 (1) (2020)
Todd Bradley, Masayuki Kuraoka, Chen-Hao Yeh, Ming Tian, Huan Chen, Derek W Cain, Xuejun Chen, Cheng Cheng, Ali H Ellebedy, Robert Parks, Maggie Barr, Laura L Sutherland, Richard M Scearce, Cindy M Bowman, Hilary Bouton-Verville, Sampa Santra, Kevin Wiehe, Mark G Lewis, Ane Ogbe, Persephone Borrow, David Montefiori, Mattia Bonsignori, M Anthony Moody, Laurent Verkoczy, Kevin O Saunders, Rajesh M Valanparambil, John R Mascola, Garnett Kelsoe, Frederick W Alt, Barton F Haynes
Immune checkpoint modulation enhances HIV-1 antibody induction. Nature communications 11 (1) (2020)
Celia C LaBranche, Rory Henderson, Allen L Hsu, Shay Behrens, Xuejun Chen, Tongqing Zhou, Kevin Wiehe, Kevin O Saunders, S Munir Alam, Mattia Bonsignori, Mario Juan Borgnia, Quentin J Sattentau, Amanda Eaton, Kelli Greene, Hongmei Gao, Hua-Xin Liao, Wilton B Williams, James Peacock, Haili Tang, Lautaro G Perez, Robert J Edwards, Thomas B Kepler, Bette T Korber, Peter D Kwong, John R Mascola, Priyamvada Acharya, Barton F Haynes, David C Montefiori
Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies. PLoS pathogens 15 (9) (2019)
Qingbo Liu, Yen-Ting Lai, Peng Zhang, Mark K Louder, Amarendra Pegu, Reda Rawi, Mangaiarkarasi Asokan, Xuejun Chen, Chen-Hsiang Shen, Gwo-Yu Chuang, Eun Sung Yang, Huiyi Miao, Yuge Wang, Anthony S Fauci, Peter D Kwong, John R Mascola, Paolo Lusso
Improvement of antibody functionality by structure-guided paratope engraftment. Nature communications 10 (1) (2019)
Boris Julg, Lawrence J Tartaglia, Brandon F Keele, Kshitij Wagh, Amarendra Pegu, Devin Sok, Peter Abbink, Stephen D Schmidt, Keyun Wang, Xuejun Chen, M Gordon Joyce, Ivelin S Georgiev, Misook Choe, Peter D Kwong, Nicole A Doria-Rose, Khoa Le, Mark K Louder, Robert T Bailer, Penny L Moore, Bette T Korber, Michael S Seaman, Salim S Abdool Karim, Lynn Morris, Richard A Koup, John R Mascola, Dennis R Burton, Dan H Barouch
Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge. Science translational medicine 9 (406) (2018)
Ling Xu, Amarendra Pegu, Ercole Rao, Nicole A Doria-Rose, Jochen Beninga, Krisha McKee, Dana M Lord, Ronnie R Wei, Gejing Deng, Mark K Louder, Stephen D Schmidt, Zachary Mankoff, Lan Wu, Mangaiarkarasi Asokan, Christian Beil, Christian Lange, Wulf Dirk Leuschner, Jochen Kruip, Rebecca Sendak, Young Do Kwon, Tongqing Zhou, Xuejun Chen, Robert T Bailer, Keyun Wang, Misook Choe, Lawrence J Tartaglia, Dan H Barouch, Sijy O'Dell, John-Paul Todd, Dennis R Burton, Mario Roederer, Mark Connors, Richard A Koup, Peter D Kwong, Zhi-Yong Yang, John R Mascola, Gary J Nabel
Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques. Science (New York, N.Y.) 358 (6359) (2017)