Seok-Yong Lee

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 38

Top Venues

Nature communications

Nature structural & molecular biology

Science (New York, N.Y.)

Nature chemical biology

Duke Medicine

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Duke Medicine Sep 01 2009

United States

Professor :: Biochemistry

Publications

Nicholas J Wright, Feng Zhang, Yang Suo, Lingyang Kong, Ying Yin, Justin G Fedor, Kedar Sharma, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Antiviral drug recognition and elevator-type transport motions of CNT3. Nature chemical biology 20 (9) (2024)
Kazuki Yamamoto, Toyotaka Sato, Aili Hao, Kenta Asao, Rintaro Kaguchi, Shintaro Kusaka, Radhakrishnam Raju Ruddarraju, Daichi Kazamori, Kiki Seo, Satoshi Takahashi, Motohiro Horiuchi, Shin-Ichi Yokota, Seok-Yong Lee, Satoshi Ichikawa
Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target. Nature communications 15 (1) (2024)
Nicholas J Wright, Feng Zhang, Yang Suo, Lingyang Kong, Ying Yin, Justin G Fedor, Kedar Sharma, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Antiviral drug recognition and elevator-type transport motions of CNT3. Nature chemical biology 20 (9) (2024)
Ying Yin, Cheon-Gyu Park, Feng Zhang, Justin G Fedor, Shasha Feng, Yang Suo, Wonpil Im, Seok-Yong Lee
Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8. Science advances 10 (31) (2024)
Ying Yin, Cheon-Gyu Park, Feng Zhang, Justin G Fedor, Shasha Feng, Yang Suo, Wonpil Im, Seok-Yong Lee
Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8. Science advances 10 (31) (2024)
Ying Yin, Cheon-Gyu Park, Feng Zhang, Justin G Fedor, Shasha Feng, Yang Suo, Wonpil Im, Seok-Yong Lee
Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8. Science advances 10 (31) (2024)
Kazuki Yamamoto, Toyotaka Sato, Aili Hao, Kenta Asao, Rintaro Kaguchi, Shintaro Kusaka, Radhakrishnam Raju Ruddarraju, Daichi Kazamori, Kiki Seo, Satoshi Takahashi, Motohiro Horiuchi, Shin-Ichi Yokota, Seok-Yong Lee, Satoshi Ichikawa
Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target. Nature communications 15 (1) (2024)
Nicholas J Wright, Feng Zhang, Yang Suo, Lingyang Kong, Ying Yin, Justin G Fedor, Kedar Sharma, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Antiviral drug recognition and elevator-type transport motions of CNT3. Nature chemical biology (2024)
Kazuki Yamamoto, Toyotaka Sato, Aili Hao, Kenta Asao, Rintaro Kaguchi, Shintaro Kusaka, Radhakrishnam Raju Ruddarraju, Daichi Kazamori, Kiki Seo, Satoshi Takahashi, Motohiro Horiuchi, Shin-Ichi Yokota, Seok-Yong Lee, Satoshi Ichikawa
Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target. Nature communications 15 (1) (2024)
Kazuki Yamamoto, Toyotaka Sato, Aili Hao, Kenta Asao, Rintaro Kaguchi, Shintaro Kusaka, Radhakrishnam Raju Ruddarraju, Daichi Kazamori, Kiki Seo, Satoshi Takahashi, Motohiro Horiuchi, Shin-Ichi Yokota, Seok-Yong Lee, Satoshi Ichikawa
Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target. Nature communications 15 (1) (2024)
Do Hoon Kwon, Feng Zhang, Brett A McCray, Meha Kumar, Jeremy M Sullivan, Charlotte J Sumner, Seok-Yong Lee
Structural insights into TRPV4-Rho GTPase signaling complex function and disease. bioRxiv : the preprint server for biology (2023)
Do Hoon Kwon, Feng Zhang, Brett A McCray, Shasha Feng, Meha Kumar, Jeremy M Sullivan, Wonpil Im, Charlotte J Sumner, Seok-Yong Lee
TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease. Nature communications 14 (1) (2023)
Yang Suo, Nicholas J Wright, Hugo Guterres, Justin G Fedor, Kevin John U Butay, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2. Nature structural & molecular biology (2023)
Yang Suo, Nicholas J Wright, Hugo Guterres, Justin G Fedor, Kevin John U Butay, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Molecular basis of polyspecific drug binding and transport by OCT1 and OCT2. bioRxiv : the preprint server for biology (2023)
Zhenning Ren, Abhishek Chhetri, Ziqiang Guan, Yang Suo, Kenichi Yokoyama, Seok-Yong Lee
Structural basis for inhibition and regulation of a chitin synthase from Candida albicans. Nature structural & molecular biology 29 (7) (2022)
Ying Yin, Feng Zhang, Shasha Feng, Kevin John U Butay, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2 . Science (New York, N.Y.) 378 (6616) (2022)
Takeshi Nakaya, Miyuki Yabe, Ellene H Mashalidis, Toyotaka Sato, Kazuki Yamamoto, Yuta Hikiji, Akira Katsuyama, Motoko Shinohara, Yusuke Minato, Satoshi Takahashi, Motohiro Horiuchi, Shin-Ichi Yokota, Seok-Yong Lee, Satoshi Ichikawa
Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY. Nature communications 13 (1) (2022)
Do Hoon Kwon, Feng Zhang, Justin G Fedor, Yang Suo, Seok-Yong Lee
Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis. Nature communications 13 (1) (2022)
Takeshi Nakaya, Miyuki Yabe, Ellene H Mashalidis, Toyotaka Sato, Kazuki Yamamoto, Yuta Hikiji, Akira Katsuyama, Motoko Shinohara, Yusuke Minato, Satoshi Takahashi, Motohiro Horiuchi, Shin-Ichi Yokota, Seok-Yong Lee, Satoshi Ichikawa
Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY. Nature communications 13 (1) (2022)
Nicholas J Wright, Justin G Fedor, Han Zhang, Pyeonghwa Jeong, Yang Suo, Jiho Yoo, Jiyong Hong, Wonpil Im, Seok-Yong Lee
Methotrexate recognition by the human reduced folate carrier SLC19A1. Nature 609 (7929) (2022)
Takeshi Nakaya, Miyuki Yabe, Ellene H Mashalidis, Toyotaka Sato, Kazuki Yamamoto, Yuta Hikiji, Akira Katsuyama, Motoko Shinohara, Yusuke Minato, Satoshi Takahashi, Motohiro Horiuchi, Shin-Ichi Yokota, Seok-Yong Lee, Satoshi Ichikawa
Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY. Nature communications 13 (1) (2022)
Takeshi Nakaya, Miyuki Yabe, Ellene H Mashalidis, Toyotaka Sato, Kazuki Yamamoto, Yuta Hikiji, Akira Katsuyama, Motoko Shinohara, Yusuke Minato, Satoshi Takahashi, Motohiro Horiuchi, Shin-Ichi Yokota, Seok-Yong Lee, Satoshi Ichikawa
Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY. Nature communications 13 (1) (2022)
Ru-Rong Ji, Seok-Yong Lee
Molecular Sensors of Temperature, Pressure, and Pain with Special Focus on TRPV1, TRPM8, and PIEZO2 Ion Channels. Neuroscience bulletin 37 (12) (2021)
Do Hoon Kwon, Feng Zhang, Yang Suo, Jonathan Bouvette, Mario Juan Borgnia, Seok-Yong Lee
Heat-dependent opening of TRPV1 in the presence of capsaicin. Nature structural & molecular biology 28 (7) (2021)
Nicholas J Wright, Seok-Yong Lee
Toward a Molecular Basis of Cellular Nucleoside Transport in Humans. Chemical reviews 121 (9) (2020)
Alvin C Y Kuk, Aili Hao, Ziqiang Guan, Seok-Yong Lee
Visualizing conformation transitions of the Lipid II flippase MurJ. Nature communications 10 (1) (2019)
Lejla Zubcevic, Allen L Hsu, Mario Juan Borgnia, Seok-Yong Lee
Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes. eLife 8 (2019)
Ying Yin, Son C Le, Allen L Hsu, Mario Juan Borgnia, Huanghe Yang, Seok-Yong Lee
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel. Science (New York, N.Y.) 363 (6430) (2019)
Ying Yin, Mengyu Wu, Allen L Hsu, William F Borschel, Mario J Borgnia, Gabriel C Lander, Seok-Yong Lee
Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel. Nature communications 10 (1) (2019)
Nicholas J Wright, Seok-Yong Lee
Structures of human ENT1 in complex with adenosine reuptake inhibitors. Nature structural & molecular biology 26 (7) (2019)
Geoffrey S Pitt, Seok-Yong Lee
Ca2+/CaM interaction with voltage-gated Na+ channels. Proceedings of the National Academy of Sciences of the United States of America (2019)
Lejla Zubcevic, William F Borschel, Allen L Hsu, Mario Juan Borgnia, Seok-Yong Lee
Regulatory switch at the cytoplasmic interface controls TRPV channel gating. eLife 8 (2019)
Ellene H Mashalidis, Benjamin Kaeser, Yuma Terasawa, Akira Katsuyama, Do-Yeon Kwon, Kiyoun Lee, Jiyong Hong, Satoshi Ichikawa, Seok-Yong Lee
Chemical logic of MraY inhibition by antibacterial nucleoside natural products. Nature communications 10 (1) (2019)
Lejla Zubcevic, Mark A Herzik, Mengyu Wu, William F Borschel, Marscha Hirschi, Albert S Song, Gabriel C Lander, Seok-Yong Lee
Conformational ensemble of the human TRPV3 ion channel. Nature communications 9 (1) (2018)
Jiho Yoo, Mengyu Wu, Ying Yin, Mark A Herzik, Gabriel C Lander, Seok-Yong Lee
Cryo-EM structure of a mitochondrial calcium uniporter. Science (New York, N.Y.) 361 (6401) (2018)
Jiho Yoo, Ellene H Mashalidis, Alvin C Y Kuk, Kazuki Yamamoto, Benjamin Kaeser, Satoshi Ichikawa, Seok-Yong Lee
GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation. Nature structural & molecular biology 25 (3) (2018)
Lejla Zubcevic, Son C Le, Huanghe Yang, Seok-Yong Lee
Conformational plasticity in the selectivity filter of the TRPV2 ion channel. Nature structural & molecular biology 25 (5) (2018)
Ying Yin, Mengyu Wu, Lejla Zubcevic, William F Borschel, Gabriel C Lander, Seok-Yong Lee
Structure of the cold- and menthol-sensing ion channel TRPM8. Science (New York, N.Y.) 359 (6372) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Seok-Yong Lee