Megumu K Saito

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 26

Top Topics

Top Venues

Life science alliance

The Journal of experimental medicine

Scientific reports

This page only lists publications with an associated author ORCID identifier.

Publications

Yukiko Takeda, Masahiro Ueki, Junpei Matsuhiro, Erik Walinda, Takayuki Tanaka, Masafumi Yamada, Hiroaki Fujita, Shunichiro Takezaki, Ichiro Kobayashi, Sakura Tamaki, Sanae Nagata, Noriko Miyake, Naomichi Matsumoto, Mitsujiro Osawa, Takahiro Yasumi, Toshio Heike, Fumiaki Ohtake, Megumu K Saito, Junya Toguchida, Junko Takita, Tadashi Ariga, Kazuhiro Iwai
A de novo dominant-negative variant is associated with OTULIN-related autoinflammatory syndrome. The Journal of experimental medicine 221 (6) (2024)
Yukiko Takeda, Masahiro Ueki, Junpei Matsuhiro, Erik Walinda, Takayuki Tanaka, Masafumi Yamada, Hiroaki Fujita, Shunichiro Takezaki, Ichiro Kobayashi, Sakura Tamaki, Sanae Nagata, Noriko Miyake, Naomichi Matsumoto, Mitsujiro Osawa, Takahiro Yasumi, Toshio Heike, Fumiaki Ohtake, Megumu K Saito, Junya Toguchida, Junko Takita, Tadashi Ariga, Kazuhiro Iwai
A de novo dominant-negative variant is associated with OTULIN-related autoinflammatory syndrome. The Journal of experimental medicine 221 (6) (2024)
Yukiko Takeda, Masahiro Ueki, Junpei Matsuhiro, Erik Walinda, Takayuki Tanaka, Masafumi Yamada, Hiroaki Fujita, Shunichiro Takezaki, Ichiro Kobayashi, Sakura Tamaki, Sanae Nagata, Noriko Miyake, Naomichi Matsumoto, Mitsujiro Osawa, Takahiro Yasumi, Toshio Heike, Fumiaki Ohtake, Megumu K Saito, Junya Toguchida, Junko Takita, Tadashi Ariga, Kazuhiro Iwai
A de novo dominant-negative variant is associated with OTULIN-related autoinflammatory syndrome. The Journal of experimental medicine 221 (6) (2024)
Yukiko Takeda, Masahiro Ueki, Junpei Matsuhiro, Erik Walinda, Takayuki Tanaka, Masafumi Yamada, Hiroaki Fujita, Shunichiro Takezaki, Ichiro Kobayashi, Sakura Tamaki, Sanae Nagata, Noriko Miyake, Naomichi Matsumoto, Mitsujiro Osawa, Takahiro Yasumi, Toshio Heike, Fumiaki Ohtake, Megumu K Saito, Junya Toguchida, Junko Takita, Tadashi Ariga, Kazuhiro Iwai
A de novo dominant-negative variant is associated with OTULIN-related autoinflammatory syndrome. The Journal of experimental medicine 221 (6) (2024)
Megumu K Saito, Mitsujiro Osawa, Nao Tsuchida, Kotaro Shiraishi, Akira Niwa, Knut Woltjen, Isao Asaka, Katsuhisa Ogata, Suminobu Ito, Shuzo Kobayashi, Shinya Yamanaka
A disease-specific iPS cell resource for studying rare and intractable diseases. Inflammation and regeneration 43 (1) (2023)
Akihiro Ikenaka, Yohko Kitagawa, Michiko Yoshida, Chuang-Yu Lin, Akira Niwa, Tatsutoshi Nakahata, Megumu K Saito
SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis. Life science alliance 6 (3) (2023)
Akihiro Ikenaka, Yohko Kitagawa, Michiko Yoshida, Chuang-Yu Lin, Akira Niwa, Tatsutoshi Nakahata, Megumu K Saito
SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis. Life science alliance 6 (3) (2023)
Akihiro Ikenaka, Yohko Kitagawa, Michiko Yoshida, Chuang-Yu Lin, Akira Niwa, Tatsutoshi Nakahata, Megumu K Saito
SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis. Life science alliance 6 (3) (2023)
Akihiro Ikenaka, Yohko Kitagawa, Michiko Yoshida, Chuang-Yu Lin, Akira Niwa, Tatsutoshi Nakahata, Megumu K Saito
SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis. Life science alliance 6 (3) (2023)
Akihiro Ikenaka, Yohko Kitagawa, Michiko Yoshida, Chuang-Yu Lin, Akira Niwa, Tatsutoshi Nakahata, Megumu K Saito
SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis. Life science alliance 6 (3) (2023)
Akihiro Ikenaka, Yohko Kitagawa, Michiko Yoshida, Chuang-Yu Lin, Akira Niwa, Tatsutoshi Nakahata, Megumu K Saito
SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis. Life science alliance 6 (3) (2023)
Shigeharu Oh, Akira Niwa, Ayako Nagahashi, Isao Asaka, Tatsutoshi Nakahata, Megumu K Saito
iPS cells from Chediak-Higashi syndrome patients recapitulate the giant granules in myeloid cells. Pediatrics international : official journal of the Japan Pediatric Society (2022)
Masahiko Nishitani-Isa, Kojiro Mukai, Yoshitaka Honda, Hiroshi Nihira, Takayuki Tanaka, Hirofumi Shibata, Kumi Kodama, Eitaro Hiejima, Kazushi Izawa, Yuri Kawasaki, Mitsujiro Osawa, Yu Katata, Sachiko Onodera, Tatsuya Watanabe, Takashi Uchida, Shigeo Kure, Junko Takita, Osamu Ohara, Megumu K Saito, Ryuta Nishikomori, Tomohiko Taguchi, Yoji Sasahara, Takahiro Yasumi
Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation. The Journal of experimental medicine 219 (6) (2022)
Megumu K Saito
Elucidation of the Pathogenesis of Autoinflammatory Diseases Using iPS Cells. Children (Basel, Switzerland) 8 (2) (2021)
Takayuki Hamabata, Katsutsugu Umeda, Kagehiro Kouzuki, Takayuki Tanaka, Tomoo Daifu, Seishiro Nodomi, Satoshi Saida, Itaru Kato, Shiro Baba, Hidefumi Hiramatsu, Mitsujiro Osawa, Akira Niwa, Megumu K Saito, Yasuhiko Kamikubo, Souichi Adachi, Yoshiko Hashii, Akira Shimada, Hiroyoshi Watanabe, Kenji Osafune, Keisuke Okita, Tatsutoshi Nakahata, Kenichiro Watanabe, Junko Takita, Toshio Heike
Author Correction: Pluripotent stem cell model of Shwachman-Diamond syndrome reveals apoptotic predisposition of hemoangiogenic progenitors. Scientific reports 11 (1) (2021)
Ryosuke Seki, Akira Ohta, Akira Niwa, Yoshinori Sugimine, Haruna Naito, Tatsutoshi Nakahata, Megumu K Saito
Induced pluripotent stem cell-derived monocytic cell lines from a NOMID patient serve as a screening platform for modulating NLRP3 inflammasome activity. PloS one 15 (8) (2020)
Naoya Kase, Madoka Terashima, Akira Ohta, Akira Niwa, Fumiko Honda-Ozaki, Yuri Kawasaki, Tatsutoshi Nakahata, Nobuo Kanazawa, Megumu K Saito
Pluripotent stem cell-based screening identifies CUDC-907 as an effective compound for restoring the in vitro phenotype of Nakajo-Nishimura syndrome. Stem cells translational medicine 10 (3) (2020)
Mitsuhiro Matsuda, Yoshihiro Yamanaka, Maya Uemura, Mitsujiro Osawa, Megumu K Saito, Ayako Nagahashi, Megumi Nishio, Long Guo, Shiro Ikegawa, Satoko Sakurai, Shunsuke Kihara, Thomas L Maurissen, Michiko Nakamura, Tomoko Matsumoto, Hiroyuki Yoshitomi, Makoto Ikeya, Noriaki Kawakami, Takuya Yamamoto, Knut Woltjen, Miki Ebisuya, Junya Toguchida, Cantas Alev
Recapitulating the human segmentation clock with pluripotent stem cells. Nature 580 (7801) (2020)
Takayuki Hamabata, Katsutsugu Umeda, Kagehiro Kouzuki, Takayuki Tanaka, Tomoo Daifu, Seishiro Nodomi, Satoshi Saida, Itaru Kato, Shiro Baba, Hidefumi Hiramatsu, Mitsujiro Osawa, Akira Niwa, Megumu K Saito, Yasuhiko Kamikubo, Souichi Adachi, Yoshiko Hashii, Akira Shimada, Hiroyoshi Watanabe, Kenji Osafune, Keisuke Okita, Tatsutoshi Nakahata, Kenichiro Watanabe, Junko Takita, Toshio Heike
Pluripotent stem cell model of Shwachman-Diamond syndrome reveals apoptotic predisposition of hemoangiogenic progenitors. Scientific reports 10 (1) (2020)
Jose Ichisima, Naoya M Suzuki, Bumpei Samata, Tomonari Awaya, Jun Takahashi, Masatoshi Hagiwara, Tatsutoshi Nakahata, Megumu K Saito
Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model. Journal of human genetics 64 (5) (2019)
Janin Grajcarek, Jean Monlong, Yoko Nishinaka-Arai, Michiko Nakamura, Miki Nagai, Shiori Matsuo, David R Lougheed, Hidetoshi Sakurai, Megumu K Saito, Guillaume Bourque, Knut Woltjen
Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations. Nature communications 10 (1) (2019)
Hiroaki Ono, Ryo Ohta, Yuri Kawasaki, Akira Niwa, Hidetoshi Takada, Tatsutoshi Nakahata, Shouichi Ohga, Megumu K Saito
Lysosomal membrane permeabilization causes secretion of IL-1β in human vascular smooth muscle cells. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 67 (10) (2018)
Kosuke Kirino, Tatsutoshi Nakahata, Tomoaki Taguchi, Megumu K Saito
Efficient derivation of sympathetic neurons from human pluripotent stem cells with a defined condition. Scientific reports 8 (1) (2018)
Takehiro Iki, Michihiro Tanaka, Shin-Ichiro Kitajiri, Tomoko Kita, Yuri Kawasaki, Akifumi Mizukoshi, Wataru Fujibuchi, Takayuki Nakagawa, Tatsutoshi Nakahata, Juichi Ito, Koichi Omori, Megumu K Saito
Microarray analyses of otospheres derived from the cochlea in the inner ear identify putative transcription factors that regulate the characteristics of otospheres. PloS one 12 (6) (2017)
Itaru Kato, Yoko Nishinaka, Masahiro Nakamura, Ayse U Akarca, Akira Niwa, Hiroki Ozawa, Kenichi Yoshida, Makiko Mori, Dapeng Wang, Makiko Morita, Hiroo Ueno, Yusuke Shiozawa, Yuichi Shiraishi, Satoru Miyano, Rajeev Gupta, Katsutsugu Umeda, Kenichiro Watanabe, Katsuyoshi Koh, Souichi Adachi, Toshio Heike, Megumu K Saito, Masashi Sanada, Seishi Ogawa, Teresa Marafioti, Akira Watanabe, Tatsutoshi Nakahata, Tariq Enver
Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA. Blood 129 (23) (2017)
Yoshinori Sugimine, Akira Niwa, Hiroyuki Matsubara, Kazuki Kobayashi, Yasuhiko Tabata, Toshio Heike, Tatsutoshi Nakahata, Megumu K Saito
A portable platform for stepwise hematopoiesis from human pluripotent stem cells within PET-reinforced collagen sponges. International journal of hematology 104 (6) (2016)