Michael Grigalunas

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 16

Top Topics

Tyrosine Kinase

High Throughput

Top Venues

Nature chemistry

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Angewandte Chemie (International ed. in English)

This page only lists publications with an associated author ORCID identifier.

Publications

Sukdev Bag, Jie Liu, Sohan Patil, Jana Bonowski, Sandra Koska, Beate Schölermann, Ruirui Zhang, Lin Wang, Axel Pahl, Sonja Sievers, Lukas Brieger, Carsten Strohmann, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
A divergent intermediate strategy yields biologically diverse pseudo-natural products. Nature chemistry 16 (6) (2024)
Lin Wang, Furkan Yilmaz, Okan Yildirim, Beate Schölermann, Sukdev Bag, Luca Greiner, Axel Pahl, Sonja Sievers, Rebecca Scheel, Carsten Strohmann, Christopher Squire, Daniel J Foley, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
Discovery of a Novel Pseudo-Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Sukdev Bag, Jie Liu, Sohan Patil, Jana Bonowski, Sandra Koska, Beate Schölermann, Ruirui Zhang, Lin Wang, Axel Pahl, Sonja Sievers, Lukas Brieger, Carsten Strohmann, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
A divergent intermediate strategy yields biologically diverse pseudo-natural products. Nature chemistry 16 (6) (2024)
Sukdev Bag, Jie Liu, Sohan Patil, Jana Bonowski, Sandra Koska, Beate Schölermann, Ruirui Zhang, Lin Wang, Axel Pahl, Sonja Sievers, Lukas Brieger, Carsten Strohmann, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
A divergent intermediate strategy yields biologically diverse pseudo-natural products. Nature chemistry 16 (6) (2024)
Lin Wang, Furkan Yilmaz, Okan Yildirim, Beate Schölermann, Sukdev Bag, Luca Greiner, Axel Pahl, Sonja Sievers, Rebecca Scheel, Carsten Strohmann, Christopher Squire, Daniel J Foley, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
Discovery of a Novel Pseudo-Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (21) (2024)
Lin Wang, Furkan Yilmaz, Okan Yildirim, Beate Schölermann, Sukdev Bag, Luca Greiner, Axel Pahl, Sonja Sievers, Rebecca Scheel, Carsten Strohmann, Christopher Squire, Daniel J Foley, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
Discovery of a Novel Pseudo-Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (21) (2024)
Lin Wang, Furkan Yilmaz, Okan Yildirim, Beate Schölermann, Sukdev Bag, Luca Greiner, Axel Pahl, Sonja Sievers, Rebecca Scheel, Carsten Strohmann, Christopher Squire, Daniel J Foley, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
Discovery of a Novel Pseudo-Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (21) (2024)
Sukdev Bag, Jie Liu, Sohan Patil, Jana Bonowski, Sandra Koska, Beate Schölermann, Ruirui Zhang, Lin Wang, Axel Pahl, Sonja Sievers, Lukas Brieger, Carsten Strohmann, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
A divergent intermediate strategy yields biologically diverse pseudo-natural products. Nature chemistry (2024)
Adrian Krzyzanowski, Axel Pahl, Michael Grigalunas, Herbert Waldmann
Spacial Score─A Comprehensive Topological Indicator for Small-Molecule Complexity. Journal of medicinal chemistry (2023)
Jie Liu, Ruirui Zhang, Shubhadip Mallick, Sohan Patil, Chantal Wientjens, Jana Flegel, Anna Krupp, Carsten Strohmann, Corentin Grassin, Christian Merten, Axel Pahl, Michael Grigalunas, Herbert Waldmann
A highly enantioselective intramolecular 1,3-dipolar cycloaddition yields novel pseudo-natural product inhibitors of the Hedgehog signalling pathway. Chemical science 14 (29) (2023)
Mohammad Akbarzadeh, Jana Flegel, Sumersing Patil, Erchang Shang, Rishikesh Narayan, Marcel Buchholzer, Neda S Kazemein Jasemi, Michael Grigalunas, Adrian Krzyzanowski, Daniel Abegg, Anton Shuster, Marco Potowski, Hacer Karatas, George Karageorgis, Niloufar Mosaddeghzadeh, Mia-Lisa Zischinsky, Christian Merten, Christopher Golz, Lucas Brieger, Carsten Strohmann, Andrey P Antonchick, Petra Janning, Alexander Adibekian, Roger S Goody, Mohammad Reza Ahmadian, Slava Ziegler, Herbert Waldmann
The Pseudo-Natural Product Rhonin Targets RHOGDI. Angewandte Chemie (International ed. in English) 61 (18) (2022)
Beate Schölermann, Jana Bonowski, Michael Grigalunas, Annina Burhop, Yusheng Xie, Joseph G F Hoock, Jie Liu, Mark Dow, Adam Nelson, Christine Nowak, Axel Pahl, Sonja Sievers, Slava Ziegler
Identification of Dihydroorotate Dehydrogenase Inhibitors Using the Cell Painting Assay. Chembiochem : a European journal of chemical biology 23 (22) (2022)
Michael Grigalunas, Sohan Patil, Adrian Krzyzanowski, Axel Pahl, Jana Flegel, Beate Schölermann, Jianing Xie, Sonja Sievers, Slava Ziegler, Herbert Waldmann
Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (67) (2022)
Robert J Young, Sabine L Flitsch, Michael Grigalunas, Paul D Leeson, Ronald J Quinn, Nicholas J Turner, Herbert Waldmann
The Time and Place for Nature in Drug Discovery. JACS Au 2 (11) (2022)
Michael Grigalunas, Susanne Brakmann, Herbert Waldmann
Chemical Evolution of Natural Product Structure. Journal of the American Chemical Society 144 (8) (2022)
Michael Grigalunas, Annina Burhop, Sarah Zinken, Axel Pahl, José-Manuel Gally, Niklas Wild, Yannik Mantel, Sonja Sievers, Daniel J Foley, Rebecca Scheel, Carsten Strohmann, Andrey P Antonchick, Herbert Waldmann
Natural product fragment combination to performance-diverse pseudo-natural products. Nature communications 12 (1) (2021)