Herbert Waldmann

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 107

Top Venues

Angewandte Chemie (International ed. in English)

Journal of medicinal chemistry

Nature chemistry

Chembiochem : a European journal of chemical biology

Max-Planck-Gesellschaft

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Max-Planck-Gesellschaft Jul 01 1999

Germany

Department Director :: Chemical Biology

Publications

Anastasia Knyazeva, Shuang Li, Dale P Corkery, Kasturika Shankar, Laura K Herzog, Xuepei Zhang, Birendra Singh, Georg Niggemeyer, David Grill, Jonathan D Gilthorpe, Massimiliano Gaetani, Lars-Anders Carlson, Herbert Waldmann, Yao-Wen Wu
A chemical inhibitor of IST1-CHMP1B interaction impairs endosomal recycling and induces noncanonical LC3 lipidation. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Anastasia Knyazeva, Shuang Li, Dale P Corkery, Kasturika Shankar, Laura K Herzog, Xuepei Zhang, Birendra Singh, Georg Niggemeyer, David Grill, Jonathan D Gilthorpe, Massimiliano Gaetani, Lars-Anders Carlson, Herbert Waldmann, Yao-Wen Wu
A chemical inhibitor of IST1-CHMP1B interaction impairs endosomal recycling and induces noncanonical LC3 lipidation. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Sohan Patil, Gregor S Cremosnik, Lara Dötsch, Jana Flegel, Britta Schulte, Kerstin C Maier, Kristina Žumer, Patrick Cramer, Petra Janning, Sonja Sievers, Slava Ziegler, Herbert Waldmann
The Pseudo-Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2. Angewandte Chemie (International ed. in English) (2024)
Sukdev Bag, Jie Liu, Sohan Patil, Jana Bonowski, Sandra Koska, Beate Schölermann, Ruirui Zhang, Lin Wang, Axel Pahl, Sonja Sievers, Lukas Brieger, Carsten Strohmann, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
A divergent intermediate strategy yields biologically diverse pseudo-natural products. Nature chemistry 16 (6) (2024)
Lara Dötsch, Caitlin Davies, Elisabeth Hennes, Julia Schönfeld, Adarsh Kumar, Celine Da Cruz Lopes Guita, Johanna H M Ehrler, Kerstin Hiesinger, Sasikala Thavam, Petra Janning, Sonja Sievers, Stefan Knapp, Ewgenij Proschak, Slava Ziegler, Herbert Waldmann
Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator. Journal of medicinal chemistry 67 (6) (2024)
Soheila Rezaei Adariani, Daya Agne, Sandra Koska, Annina Burhop, Carina Seitz, Jens Warmers, Petra Janning, Malte Metz, Axel Pahl, Sonja Sievers, Herbert Waldmann, Slava Ziegler
Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay. Journal of medicinal chemistry (2024)
A Lina Heinzke, Axel Pahl, Barbara Zdrazil, Andrew R Leach, Herbert Waldmann, Robert J Young, Paul D Leeson
Occurrence of "Natural Selection" in Successful Small Molecule Drug Discovery. Journal of medicinal chemistry 67 (13) (2024)
Axel Pahl, Jie Liu, Sohan Patil, Soheila Rezaei Adariani, Beate Schölermann, Jens Warmers, Jana Bonowski, Sandra Koska, Yasemin Akbulut, Carina Seitz, Sonja Sievers, Slava Ziegler, Herbert Waldmann
Illuminating Dark Chemical Matter Using the Cell Painting Assay. Journal of medicinal chemistry 67 (11) (2024)
Axel Pahl, Jie Liu, Sohan Patil, Soheila Rezaei Adariani, Beate Schölermann, Jens Warmers, Jana Bonowski, Sandra Koska, Yasemin Akbulut, Carina Seitz, Sonja Sievers, Slava Ziegler, Herbert Waldmann
Illuminating Dark Chemical Matter Using the Cell Painting Assay. Journal of medicinal chemistry (2024)
A Lina Heinzke, Axel Pahl, Barbara Zdrazil, Andrew R Leach, Herbert Waldmann, Robert J Young, Paul D Leeson
Occurrence of "Natural Selection" in Successful Small Molecule Drug Discovery. Journal of medicinal chemistry 67 (13) (2024)
Aishvarya Tandon, Anna Santura, Herbert Waldmann, Axel Pahl, Paul Czodrowski
Identification of lysosomotropism using explainable machine learning and morphological profiling cell painting data. RSC medicinal chemistry 15 (8) (2024)
Anastasia Knyazeva, Shuang Li, Dale P Corkery, Kasturika Shankar, Laura K Herzog, Xuepei Zhang, Birendra Singh, Georg Niggemeyer, David Grill, Jonathan D Gilthorpe, Massimiliano Gaetani, Lars-Anders Carlson, Herbert Waldmann, Yao-Wen Wu
A chemical inhibitor of IST1-CHMP1B interaction impairs endosomal recycling and induces noncanonical LC3 lipidation. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Lara Dötsch, Caitlin Davies, Elisabeth Hennes, Julia Schönfeld, Adarsh Kumar, Celine Da Cruz Lopes Guita, Johanna H M Ehrler, Kerstin Hiesinger, Sasikala Thavam, Petra Janning, Sonja Sievers, Stefan Knapp, Ewgenij Proschak, Slava Ziegler, Herbert Waldmann
Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator. Journal of medicinal chemistry 67 (6) (2024)
Axel Pahl, Jie Liu, Sohan Patil, Soheila Rezaei Adariani, Beate Schölermann, Jens Warmers, Jana Bonowski, Sandra Koska, Yasemin Akbulut, Carina Seitz, Sonja Sievers, Slava Ziegler, Herbert Waldmann
Illuminating Dark Chemical Matter Using the Cell Painting Assay. Journal of medicinal chemistry 67 (11) (2024)
A Lina Heinzke, Axel Pahl, Barbara Zdrazil, Andrew R Leach, Herbert Waldmann, Robert J Young, Paul D Leeson
Occurrence of "Natural Selection" in Successful Small Molecule Drug Discovery. Journal of medicinal chemistry 67 (13) (2024)
Lin Wang, Furkan Yilmaz, Okan Yildirim, Beate Schölermann, Sukdev Bag, Luca Greiner, Axel Pahl, Sonja Sievers, Rebecca Scheel, Carsten Strohmann, Christopher Squire, Daniel J Foley, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
Discovery of a Novel Pseudo-Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Axel Pahl, Jie Liu, Sohan Patil, Soheila Rezaei Adariani, Beate Schölermann, Jens Warmers, Jana Bonowski, Sandra Koska, Yasemin Akbulut, Carina Seitz, Sonja Sievers, Slava Ziegler, Herbert Waldmann
Illuminating Dark Chemical Matter Using the Cell Painting Assay. Journal of medicinal chemistry 67 (11) (2024)
Soheila Rezaei Adariani, Daya Agne, Sandra Koska, Annina Burhop, Carina Seitz, Jens Warmers, Petra Janning, Malte Metz, Axel Pahl, Sonja Sievers, Herbert Waldmann, Slava Ziegler
Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay. Journal of medicinal chemistry 67 (15) (2024)
Lara Dötsch, Caitlin Davies, Elisabeth Hennes, Julia Schönfeld, Adarsh Kumar, Celine Da Cruz Lopes Guita, Johanna H M Ehrler, Kerstin Hiesinger, Sasikala Thavam, Petra Janning, Sonja Sievers, Stefan Knapp, Ewgenij Proschak, Slava Ziegler, Herbert Waldmann
Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator. Journal of medicinal chemistry 67 (6) (2024)
Lara Dötsch, Caitlin Davies, Elisabeth Hennes, Julia Schönfeld, Adarsh Kumar, Celine Da Cruz Lopes Guita, Johanna H M Ehrler, Kerstin Hiesinger, Sasikala Thavam, Petra Janning, Sonja Sievers, Stefan Knapp, Ewgenij Proschak, Slava Ziegler, Herbert Waldmann
Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator. Journal of medicinal chemistry (2024)
Anastasia Knyazeva, Shuang Li, Dale P Corkery, Kasturika Shankar, Laura K Herzog, Xuepei Zhang, Birendra Singh, Georg Niggemeyer, David Grill, Jonathan D Gilthorpe, Massimiliano Gaetani, Lars-Anders Carlson, Herbert Waldmann, Yao-Wen Wu
A chemical inhibitor of IST1-CHMP1B interaction impairs endosomal recycling and induces noncanonical LC3 lipidation. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Soheila Rezaei Adariani, Daya Agne, Sandra Koska, Annina Burhop, Carina Seitz, Jens Warmers, Petra Janning, Malte Metz, Axel Pahl, Sonja Sievers, Herbert Waldmann, Slava Ziegler
Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay. Journal of medicinal chemistry 67 (15) (2024)
Elisabeth Hennes, Belén Lucas, Natalie S Scholes, Xiu-Fen Cheng, Daniel C Scott, Matthias Bischoff, Katharina Reich, Raphael Gasper, María Lucas, Teng Teng Xu, Lisa-Marie Pulvermacher, Lara Dötsch, Hana Imrichova, Alexandra Brause, Kesava Reddy Naredla, Sonja Sievers, Kamal Kumar, Petra Janning, Malte Gersch, Peter J Murray, Brenda A Schulman, Georg E Winter, Slava Ziegler, Herbert Waldmann
Monovalent Pseudo-Natural Product Degraders Supercharge the Native Degradation of IDO1 by KLHDC3. bioRxiv : the preprint server for biology (2024)
Sohan Patil, Gregor S Cremosnik, Lara Dötsch, Jana Flegel, Britta Schulte, Kerstin C Maier, Kristina Žumer, Patrick Cramer, Petra Janning, Sonja Sievers, Slava Ziegler, Herbert Waldmann
The Pseudo-Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2. Angewandte Chemie (International ed. in English) 63 (32) (2024)
A Lina Heinzke, Axel Pahl, Barbara Zdrazil, Andrew R Leach, Herbert Waldmann, Robert J Young, Paul D Leeson
Occurrence of "Natural Selection" in Successful Small Molecule Drug Discovery. Journal of medicinal chemistry 67 (13) (2024)
Soheila Rezaei Adariani, Daya Agne, Sandra Koska, Annina Burhop, Carina Seitz, Jens Warmers, Petra Janning, Malte Metz, Axel Pahl, Sonja Sievers, Herbert Waldmann, Slava Ziegler
Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay. Journal of medicinal chemistry 67 (15) (2024)
Sukdev Bag, Jie Liu, Sohan Patil, Jana Bonowski, Sandra Koska, Beate Schölermann, Ruirui Zhang, Lin Wang, Axel Pahl, Sonja Sievers, Lukas Brieger, Carsten Strohmann, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
A divergent intermediate strategy yields biologically diverse pseudo-natural products. Nature chemistry 16 (6) (2024)
Axel Pahl, Oleksandr O Grygorenko, Ivan S Kondratov, Herbert Waldmann
Identification of readily available pseudo-natural products. RSC medicinal chemistry 15 (8) (2024)
Sohan Patil, Gregor S Cremosnik, Lara Dötsch, Jana Flegel, Britta Schulte, Kerstin C Maier, Kristina Žumer, Patrick Cramer, Petra Janning, Sonja Sievers, Slava Ziegler, Herbert Waldmann
The Pseudo-Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2. Angewandte Chemie (International ed. in English) 63 (32) (2024)
Sohan Patil, Gregor S Cremosnik, Lara Dötsch, Jana Flegel, Britta Schulte, Kerstin C Maier, Kristina Žumer, Patrick Cramer, Petra Janning, Sonja Sievers, Slava Ziegler, Herbert Waldmann
The Pseudo-Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2. Angewandte Chemie (International ed. in English) 63 (32) (2024)
Sukdev Bag, Jie Liu, Sohan Patil, Jana Bonowski, Sandra Koska, Beate Schölermann, Ruirui Zhang, Lin Wang, Axel Pahl, Sonja Sievers, Lukas Brieger, Carsten Strohmann, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
A divergent intermediate strategy yields biologically diverse pseudo-natural products. Nature chemistry 16 (6) (2024)
Aishvarya Tandon, Anna Santura, Herbert Waldmann, Axel Pahl, Paul Czodrowski
Identification of lysosomotropism using explainable machine learning and morphological profiling cell painting data. RSC medicinal chemistry 15 (8) (2024)
Anastasia Knyazeva, Shuang Li, Dale P Corkery, Kasturika Shankar, Laura K Herzog, Xuepei Zhang, Birendra Singh, Georg Niggemeyer, David Grill, Jonathan D Gilthorpe, Massimiliano Gaetani, Lars-Anders Carlson, Herbert Waldmann, Yao-Wen Wu
A chemical inhibitor of IST1-CHMP1B interaction impairs endosomal recycling and induces noncanonical LC3 lipidation. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Lara Dötsch, Caitlin Davies, Elisabeth Hennes, Julia Schönfeld, Adarsh Kumar, Celine Da Cruz Lopes Guita, Johanna H M Ehrler, Kerstin Hiesinger, Sasikala Thavam, Petra Janning, Sonja Sievers, Stefan Knapp, Ewgenij Proschak, Slava Ziegler, Herbert Waldmann
Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator. Journal of medicinal chemistry 67 (6) (2024)
Lin Wang, Furkan Yilmaz, Okan Yildirim, Beate Schölermann, Sukdev Bag, Luca Greiner, Axel Pahl, Sonja Sievers, Rebecca Scheel, Carsten Strohmann, Christopher Squire, Daniel J Foley, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
Discovery of a Novel Pseudo-Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (21) (2024)
Elisabeth Hennes, Belén Lucas, Natalie S Scholes, Xiu-Fen Cheng, Daniel C Scott, Matthias Bischoff, Katharina Reich, Raphael Gasper, María Lucas, Teng Teng Xu, Lisa-Marie Pulvermacher, Lara Dötsch, Hana Imrichova, Alexandra Brause, Kesava Reddy Naredla, Sonja Sievers, Kamal Kumar, Petra Janning, Malte Gersch, Peter J Murray, Brenda A Schulman, Georg E Winter, Slava Ziegler, Herbert Waldmann
Monovalent Pseudo-Natural Product Degraders Supercharge the Native Degradation of IDO1 by KLHDC3. bioRxiv : the preprint server for biology (2024)
A Lina Heinzke, Axel Pahl, Barbara Zdrazil, Andrew R Leach, Herbert Waldmann, Robert J Young, Paul D Leeson
Occurrence of "Natural Selection" in Successful Small Molecule Drug Discovery. Journal of medicinal chemistry (2024)
Marko Cigler, Hana Imrichova, Fabian Frommelt, Lucie Caramelle, Laura Depta, Andrea Rukavina, Chrysanthi Kagiou, J Thomas Hannich, Cristina Mayor-Ruiz, Giulio Superti-Furga, Sonja Sievers, Alison Forrester, Luca Laraia, Herbert Waldmann, Georg E Winter
Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP. Nature chemical biology (2024)
Lin Wang, Furkan Yilmaz, Okan Yildirim, Beate Schölermann, Sukdev Bag, Luca Greiner, Axel Pahl, Sonja Sievers, Rebecca Scheel, Carsten Strohmann, Christopher Squire, Daniel J Foley, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
Discovery of a Novel Pseudo-Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (21) (2024)
Lin Wang, Furkan Yilmaz, Okan Yildirim, Beate Schölermann, Sukdev Bag, Luca Greiner, Axel Pahl, Sonja Sievers, Rebecca Scheel, Carsten Strohmann, Christopher Squire, Daniel J Foley, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
Discovery of a Novel Pseudo-Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (21) (2024)
Sukdev Bag, Jie Liu, Sohan Patil, Jana Bonowski, Sandra Koska, Beate Schölermann, Ruirui Zhang, Lin Wang, Axel Pahl, Sonja Sievers, Lukas Brieger, Carsten Strohmann, Slava Ziegler, Michael Grigalunas, Herbert Waldmann
A divergent intermediate strategy yields biologically diverse pseudo-natural products. Nature chemistry (2024)
Soheila Rezaei Adariani, Daya Agne, Sandra Koska, Annina Burhop, Carina Seitz, Jens Warmers, Petra Janning, Malte Metz, Axel Pahl, Sonja Sievers, Herbert Waldmann, Slava Ziegler
Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay. Journal of medicinal chemistry 67 (15) (2024)
Axel Pahl, Oleksandr O Grygorenko, Ivan S Kondratov, Herbert Waldmann
Identification of readily available pseudo-natural products. RSC medicinal chemistry 15 (8) (2024)
Yuquan Tong, Yeongju Lee, Xiaohui Liu, Jessica L Childs-Disney, Blessy M Suresh, Raphael I Benhamou, Chunying Yang, Weimin Li, Matthew G Costales, Hafeez S Haniff, Sonja Sievers, Daniel Abegg, Tristan Wegner, Tiffany O Paulisch, Elizabeth Lekah, Maison Grefe, Gogce Crynen, Montina Van Meter, Tenghui Wang, Quentin M R Gibaut, John L Cleveland, Alexander Adibekian, Frank Glorius, Herbert Waldmann, Matthew D Disney
Programming inactive RNA-binding small molecules into bioactive degraders. Nature (2023)
Gang Xue, Jianing Xie, Matthias Hinterndorfer, Marko Cigler, Lara Dötsch, Hana Imrichova, Philipp Lampe, Xiufen Cheng, Soheila Rezaei Adariani, Georg E Winter, Herbert Waldmann
Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype. Nature communications 14 (1) (2023)
Adrian Krzyzanowski, Axel Pahl, Michael Grigalunas, Herbert Waldmann
Spacial Score─A Comprehensive Topological Indicator for Small-Molecule Complexity. Journal of medicinal chemistry (2023)
Jie Liu, Ruirui Zhang, Shubhadip Mallick, Sohan Patil, Chantal Wientjens, Jana Flegel, Anna Krupp, Carsten Strohmann, Corentin Grassin, Christian Merten, Axel Pahl, Michael Grigalunas, Herbert Waldmann
A highly enantioselective intramolecular 1,3-dipolar cycloaddition yields novel pseudo-natural product inhibitors of the Hedgehog signalling pathway. Chemical science 14 (29) (2023)
Caitlin Davies, Lara Dötsch, Maria Gessica Ciulla, Elisabeth Hennes, Kei Yoshida, Raphael Gasper, Rebecca Scheel, Sonja Sievers, Carsten Strohmann, Kamal Kumar, Slava Ziegler, Herbert Waldmann
Identification of a Novel Pseudo-Natural Product Type IV IDO1 Inhibitor Chemotype. Angewandte Chemie (International ed. in English) 61 (40) (2022)
Hiromasa Yoshioka, Tatsuro Kawamura, Makoto Muroi, Yasumitsu Kondoh, Kaori Honda, Makoto Kawatani, Harumi Aono, Herbert Waldmann, Nobumoto Watanabe, Hiroyuki Osada
Identification of a Small Molecule That Enhances Ferroptosis via Inhibition of Ferroptosis Suppressor Protein 1 (FSP1). ACS chemical biology 17 (2) (2022)
Adrian Krzyzanowski, Lea Marie Esser, Anthony Willaume, Renaud Prudent, Christoph Peter, Peter 't Hart, Herbert Waldmann
Development of Macrocyclic PRMT5-Adaptor Protein Interaction Inhibitors. Journal of medicinal chemistry 65 (22) (2022)
Georg Niggemeyer, Anastasia Knyazeva, Raphael Gasper, Dale Corkery, Pia Bodenbinder, Julian J Holstein, Sonja Sievers, Yao-Wen Wu, Herbert Waldmann
Synthesis of 20-Membered Macrocyclic Pseudo-Natural Products Yields Inducers of LC3 Lipidation. Angewandte Chemie (International ed. in English) 61 (11) (2022)
Jana Flegel, Saad Shaaban, Zhi Jun Jia, Britta Schulte, Yilong Lian, Adrian Krzyzanowski, Malte Metz, Tabea Schneidewind, Fabian Wesseler, Anke Flegel, Alisa Reich, Alexandra Brause, Gang Xue, Minghao Zhang, Lara Dötsch, Isabelle D Stender, Jan-Erik Hoffmann, Rebecca Scheel, Petra Janning, Fraydoon Rastinejad, Dennis Schade, Carsten Strohmann, Andrey P Antonchick, Sonja Sievers, Pedro Moura-Alves, Slava Ziegler, Herbert Waldmann
The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation. Journal of medicinal chemistry (2022)
Lea Katharina Picard, Elisabeth Littwitz-Salomon, Herbert Waldmann, Carsten Watzl
Inhibition of Glucose Uptake Blocks Proliferation but Not Cytotoxic Activity of NK Cells. Cells 11 (21) (2022)
Mohammad Akbarzadeh, Jana Flegel, Sumersing Patil, Erchang Shang, Rishikesh Narayan, Marcel Buchholzer, Neda S Kazemein Jasemi, Michael Grigalunas, Adrian Krzyzanowski, Daniel Abegg, Anton Shuster, Marco Potowski, Hacer Karatas, George Karageorgis, Niloufar Mosaddeghzadeh, Mia-Lisa Zischinsky, Christian Merten, Christopher Golz, Lucas Brieger, Carsten Strohmann, Andrey P Antonchick, Petra Janning, Alexander Adibekian, Roger S Goody, Mohammad Reza Ahmadian, Slava Ziegler, Herbert Waldmann
The Pseudo-Natural Product Rhonin Targets RHOGDI. Angewandte Chemie (International ed. in English) 61 (18) (2022)
Daniel J Foley, Herbert Waldmann
Ketones as strategic building blocks for the synthesis of natural product-inspired compounds. Chemical Society reviews 51 (10) (2022)
Michael Grigalunas, Sohan Patil, Adrian Krzyzanowski, Axel Pahl, Jana Flegel, Beate Schölermann, Jianing Xie, Sonja Sievers, Slava Ziegler, Herbert Waldmann
Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (67) (2022)
Fabian Wesseler, Daniel Riege, Mahesh Puthanveedu, Jonas Halver, Eva Müller, Jessica Bertrand, Andrey P Antonchick, Sonja Sievers, Herbert Waldmann, Dennis Schade
Probing Embryonic Development Enables the Discovery of Unique Small-Molecule Bone Morphogenetic Protein Potentiators. Journal of medicinal chemistry 65 (5) (2022)
Fabian Wesseler, Stefan Lohmann, Daniel Riege, Jonas Halver, Aileen Roth, Christian Pichlo, Sabrina Weber, Masanari Takamiya, Eva Müller, Jana Ketzel, Jana Flegel, Adrian Gihring, Sepand Rastegar, Jessica Bertrand, Ulrich Baumann, Uwe Knippschild, Christian Peifer, Sonja Sievers, Herbert Waldmann, Dennis Schade
Phenotypic Discovery of Triazolo[1,5- c ]quinazolines as a First-In-Class Bone Morphogenetic Protein Amplifier Chemotype. Journal of medicinal chemistry 65 (22) (2022)
Robert J Young, Sabine L Flitsch, Michael Grigalunas, Paul D Leeson, Ronald J Quinn, Nicholas J Turner, Herbert Waldmann
The Time and Place for Nature in Drug Discovery. JACS Au 2 (11) (2022)
Michael Grigalunas, Susanne Brakmann, Herbert Waldmann
Chemical Evolution of Natural Product Structure. Journal of the American Chemical Society 144 (8) (2022)
Elisabeth Hennes, Philipp Lampe, Lara Dötsch, Nora Bruning, Lisa-Marie Pulvermacher, Sonja Sievers, Slava Ziegler, Herbert Waldmann
Cell-Based Identification of New IDO1 Modulator Chemotypes. Angewandte Chemie (International ed. in English) 60 (18) (2021)
Annina Burhop, Sukdev Bag, Michael Grigalunas, Sophie Woitalla, Pia Bodenbinder, Lukas Brieger, Carsten Strohmann, Axel Pahl, Sonja Sievers, Herbert Waldmann
Synthesis of Indofulvin Pseudo-Natural Products Yields a New Autophagy Inhibitor Chemotype. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 8 (19) (2021)
Michael Grigalunas, Annina Burhop, Sarah Zinken, Axel Pahl, José-Manuel Gally, Niklas Wild, Yannik Mantel, Sonja Sievers, Daniel J Foley, Rebecca Scheel, Carsten Strohmann, Andrey P Antonchick, Herbert Waldmann
Natural product fragment combination to performance-diverse pseudo-natural products. Nature communications 12 (1) (2021)
Okan Yildirim, Michael Grigalunas, Lukas Brieger, Carsten Strohmann, Andrey P Antonchick, Herbert Waldmann
Dynamic Catalytic Highly Enantioselective 1,3-Dipolar Cycloadditions. Angewandte Chemie (International ed. in English) 60 (36) (2021)
George Karageorgis, Daniel J Foley, Luca Laraia, Susanne Brakmann, Herbert Waldmann
Pseudo Natural Products-Chemical Evolution of Natural Product Structure. Angewandte Chemie (International ed. in English) 60 (29) (2021)
Saad Shaaban, Christian Merten, Herbert Waldmann
Catalytic Atroposelective C7 Functionalisation of Indolines and Indoles. Chemistry (Weinheim an der Bergstrasse, Germany) (2021)
Adrian Krzyzanowski, Raphael Gasper, Hélène Adihou, Peter 't Hart, Herbert Waldmann
Biochemical Investigation of the Interaction of pICln, RioK1 and COPR5 with the PRMT5-MEP50 Complex. Chembiochem : a European journal of chemical biology 22 (11) (2021)
Jie Liu, Gregor S Cremosnik, Felix Otte, Axel Pahl, Sonja Sievers, Carsten Strohmann, Herbert Waldmann
Design, Synthesis, and Biological Evaluation of Chemically and Biologically Diverse Pyrroquinoline Pseudo Natural Products. Angewandte Chemie (International ed. in English) 60 (9) (2021)
Gregor S Cremosnik, Jie Liu, Herbert Waldmann
Guided by evolution: from biology oriented synthesis to pseudo natural products. Natural product reports 37 (11) (2021)
José-Manuel Gally, Axel Pahl, Paul Czodrowski, Herbert Waldmann
Pseudonatural Products Occur Frequently in Biologically Relevant Compounds. Journal of chemical information and modeling 61 (11) (2021)
Jie Liu, Jana Flegel, Felix Otte, Axel Pahl, Sonja Sievers, Carsten Strohmann, Herbert Waldmann
Combination of Pseudo-Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo-Sesquiterpenoid Alkaloids. Angewandte Chemie (International ed. in English) 60 (39) (2021)
Peter 't Hart, Pascal Hommen, Anaïs Noisier, Adrian Krzyzanowski, Darijan Schüler, Arthur T Porfetye, Mohammad Akbarzadeh, Ingrid R Vetter, Hélène Adihou, Herbert Waldmann
Structure Based Design of Bicyclic Peptide Inhibitors of RbAp48. Angewandte Chemie (International ed. in English) 60 (4) (2020)
Tomoyuki Furuta, Yuya Mizukami, Lisa Asano, Kenjiro Kotake, Slava Ziegler, Hiroki Yoshida, Mizuki Watanabe, Shin-Ichi Sato, Herbert Waldmann, Makiya Nishikawa, Motonari Uesugi
Correction to "Nutrient-Based Chemical Library as a Source of Energy Metabolism Modulators". ACS chemical biology 15 (8) (2020)
Hélène Adihou, Ranganath Gopalakrishnan, Tim Förster, Stéphanie M Guéret, Raphael Gasper, Stefan Geschwindner, Carmen Carrillo García, Hacer Karatas, Ajaybabu V Pobbati, Mercedes Vazquez-Chantada, Paul Davey, Carola M Wassvik, Jeremy Kah Sheng Pang, Boon-Seng Soh, Wanjin Hong, Elisabetta Chiarparin, Dennis Schade, Alleyn T Plowright, Eric Valeur, Malin Lemurell, Tom N Grossmann, Herbert Waldmann
A protein tertiary structure mimetic modulator of the Hippo signalling pathway. Nature communications 11 (1) (2020)
Luca Laraia, Guillaume Garivet, Daniel J Foley, Nadine Kaiser, Sebastian Müller, Sarah Zinken, Thomas Pinkert, Julian Wilke, Dale Corkery, Axel Pahl, Sonja Sievers, Petra Janning, Christoph Arenz, Yaowen Wu, Raphaël Rodriguez, Herbert Waldmann
Image-Based Morphological Profiling Identifies a Lysosomotropic, Iron-Sequestering Autophagy Inhibitor. Angewandte Chemie (International ed. in English) 59 (14) (2020)
Saad Shaaban, Caitlin Davies, Christian Merten, Jana Flegel, Felix Otte, Carsten Strohmann, Herbert Waldmann
RhIII -Catalyzed C-H Activation of Aryl Hydroxamates for the Synthesis of Isoindolinones. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (47) (2020)
George Karageorgis, Daniel J Foley, Luca Laraia, Herbert Waldmann
Principle and design of pseudo-natural products. Nature chemistry 12 (3) (2020)
Tatsuro Kawamura, Yushi Futamura, Erchang Shang, Makoto Muroi, Petra Janning, Masayoshi Ueno, Julian Wilke, Shigeki Takeda, Yasumitsu Kondoh, Slava Ziegler, Nobumoto Watanabe, Herbert Waldmann, Hiroyuki Osada
Discovery of small-molecule modulator of heterotrimeric Gi-protein by integrated phenotypic profiling and chemical proteomics. Bioscience, biotechnology, and biochemistry 84 (12) (2020)
Daniel J Foley, Sarah Zinken, Dale P Corkery, Luca Laraia, Axel Pahl, Yao-Wen Wu, Herbert Waldmann
Phenotyping Reveals Targets of a Pseudo-Natural-Product Autophagy Inhibitor. Angewandte Chemie (International ed. in English) 59 (30) (2020)
Stéphanie M Guéret, Sasikala Thavam, Rodrigo J Carbajo, Marco Potowski, Niklas Larsson, Göran Dahl, Anita Dellsén, Tom N Grossmann, Alleyn T Plowright, Eric Valeur, Malin Lemurell, Herbert Waldmann
Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments. Journal of the American Chemical Society 142 (10) (2020)
Hacer Karatas, Mohammad Akbarzadeh, Hélène Adihou, Gernot Hahne, Ajaybabu V Pobbati, Elizabeth Yihui Ng, Stéphanie M Guéret, Sonja Sievers, Axel Pahl, Malte Metz, Sarah Zinken, Lara Dötsch, Christine Nowak, Sasikala Thavam, Alexandra Friese, CongBao Kang, Wanjin Hong, Herbert Waldmann
Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain Central Pocket. Journal of medicinal chemistry 63 (20) (2020)
Tabea Schneidewind, Alexandra Brause, Axel Pahl, Annina Burhop, Tom Mejuch, Sonja Sievers, Herbert Waldmann, Slava Ziegler
Morphological Profiling Identifies a Common Mode of Action for Small Molecules with Different Targets. Chembiochem : a European journal of chemical biology 21 (22) (2020)
Michael Winzker, Alexandra Friese, Uwe Koch, Petra Janning, Slava Ziegler, Herbert Waldmann
Development of a PDEδ-Targeting PROTACs that Impair Lipid Metabolism. Angewandte Chemie (International ed. in English) 59 (14) (2020)
Saad Shaaban, Houhua Li, Felix Otte, Carsten Strohmann, Andrey P Antonchick, Herbert Waldmann
Enantioselective Synthesis of Five-Membered-Ring Atropisomers with a Chiral Rh(III) Complex. Organic letters 22 (23) (2020)
Ajaybabu V Pobbati, Tom Mejuch, Sayan Chakraborty, Hacer Karatas, Sakshibeedu R Bharath, Stéphanie M Guéret, Pierre-Alexis Goy, Gernot Hahne, Axel Pahl, Sonja Sievers, Ernesto Guccione, Haiwei Song, Herbert Waldmann, Wanjin Hong
Identification of Quinolinols as Activators of TEAD-Dependent Transcription. ACS chemical biology 14 (12) (2019)
Alexandra Friese, Shobhna Kapoor, Tabea Schneidewind, Srinivasa Rao Vidadala, Juhi Sardana, Alexandra Brause, Tim Förster, Matthias Bischoff, Jessica Wagner, Petra Janning, Slava Ziegler, Herbert Waldmann
Chemical Genetics Reveals a Role of dCTP Pyrophosphatase 1 in Wnt Signaling. Angewandte Chemie (International ed. in English) 58 (37) (2019)
Lea Kremer, Elisabeth Hennes, Alexandra Brause, Andrei Ursu, Lucas Robke, Hideaki T Matsubayashi, Yuta Nihongaki, Jana Flegel, Ivana Mejdrová, Jan Eickhoff, Matthias Baumann, Radim Nencka, Petra Janning, Susanne Kordes, Hans R Schöler, Jared Sterneckert, Takanari Inoue, Slava Ziegler, Herbert Waldmann
Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß. Angewandte Chemie (International ed. in English) 58 (46) (2019)
Andreas Christoforow, Julian Wilke, Aylin Binici, Axel Pahl, Claude Ostermann, Sonja Sievers, Herbert Waldmann
Design, Synthesis, and Phenotypic Profiling of Pyrano-Furo-Pyridone Pseudo Natural Products. Angewandte Chemie (International ed. in English) 58 (41) (2019)
Javier Ceballos, Melanie Schwalfenberg, George Karageorgis, Elena S Reckzeh, Sonja Sievers, Claude Ostermann, Axel Pahl, Magnus Sellstedt, Jessica Nowacki, Marjorie A Carnero Corrales, Julian Wilke, Luca Laraia, Kirsten Tschapalda, Malte Metz, Dominik A Sehr, Silke Brand, Konstanze Winklhofer, Petra Janning, Slava Ziegler, Herbert Waldmann
Synthesis of Indomorphan Pseudo-Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3. Angewandte Chemie (International ed. in English) 58 (47) (2019)
Yao-Wen Wu, Herbert Waldmann
Toward the role of cholesterol and cholesterol transfer protein in autophagosome biogenesis. Autophagy 15 (12) (2019)
Elena S Reckzeh, Herbert Waldmann
Small-Molecule Inhibition of Glucose Transporters GLUT-1-4. Chembiochem : a European journal of chemical biology 21 (1-2) (2019)
Tomoyuki Furuta, Yuya Mizukami, Lisa Asano, Kenjiro Kotake, Slava Ziegler, Hiroki Yoshida, Mizuki Watanabe, Shin-Ichi Sato, Herbert Waldmann, Makiya Nishikawa, Motonari Uesugi
Nutrient-Based Chemical Library as a Source of Energy Metabolism Modulators. ACS chemical biology 14 (9) (2019)
Luca Laraia, Alexandra Friese, Dale P Corkery, Georgios Konstantinidis, Nelli Erwin, Walter Hofer, Hacer Karatas, Laura Klewer, Andreas Brockmeyer, Malte Metz, Beate Schölermann, Mridula Dwivedi, Lei Li, Pablo Rios-Munoz, Maja Köhn, Roland Winter, Ingrid R Vetter, Slava Ziegler, Petra Janning, Yao-Wen Wu, Herbert Waldmann
The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nature chemical biology 15 (7) (2019)
Houhua Li, Rajesh Gontla, Jana Flegel, Christian Merten, Slava Ziegler, Andrey P Antonchick, Herbert Waldmann
Enantioselective Formal C(sp3 )-H Bond Activation in the Synthesis of Bioactive Spiropyrazolone Derivatives. Angewandte Chemie (International ed. in English) 58 (1) (2018)
George Karageorgis, Elena S Reckzeh, Javier Ceballos, Melanie Schwalfenberg, Sonja Sievers, Claude Ostermann, Axel Pahl, Slava Ziegler, Herbert Waldmann
Chromopynones are pseudo natural product glucose uptake inhibitors targeting glucose transporters GLUT-1 and -3. Nature chemistry 10 (11) (2018)
Nadine Kaiser, Tom Mejuch, Roman Fedoryshchak, Petra Janning, Edward W Tate, Herbert Waldmann
Photoactivatable Myristic Acid Probes for UNC119-Cargo Interactions. Chembiochem : a European journal of chemical biology 20 (2) (2018)
Yen-Chun Lee, Kamal Kumar, Herbert Waldmann
Ligand-Directed Divergent Synthesis of Carbo- and Heterocyclic Ring Systems. Angewandte Chemie (International ed. in English) 57 (19) (2018)
Gang Shan, Jana Flegel, Houhua Li, Christian Merten, Slava Ziegler, Andrey P Antonchick, Herbert Waldmann
C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors. Angewandte Chemie (International ed. in English) 57 (43) (2018)
Zhi-Jun Jia, Gang Shan, Constantin G Daniliuc, Andrey P Antonchick, Herbert Waldmann
Enantioselective Synthesis of the Spirotropanyl Oxindole Scaffold through Bimetallic Relay Catalysis. Angewandte Chemie (International ed. in English) 57 (44) (2018)
Zhi-Jun Jia, Hiroshi Takayama, Yushi Futamura, Harumi Aono, Jonathan O Bauer, Carsten Strohmann, Andrey P Antonchick, Hiroyuki Osada, Herbert Waldmann
Catalytic Enantioselective Synthesis of a Pyrrolizidine-Alkaloid-Inspired Compound Collection with Antiplasmodial Activity. The Journal of organic chemistry 83 (13) (2018)

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Herbert Waldmann