Robert J Young

ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 12

Top Venues

Journal of medicinal chemistry

SLAS discovery : advancing life sciences R & D

Biochemistry

Expert opinion on drug discovery

Blue Burgundy

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Blue Burgundy Sep 01 2019

United Kingdom

Principal

GlaxoSmithKline Plc Feb 14 1990 - Jul 05 2019

United Kingdom

GSK Fellow, Senior Scientific Investigator :: NCE Medicinal Chemistry

Publications

Robert J Young
Today's drug discovery and the shadow of the rule of 5. Expert opinion on drug discovery (2023)
Robert J Young, Sabine L Flitsch, Michael Grigalunas, Paul D Leeson, Ronald J Quinn, Nicholas J Turner, Herbert Waldmann
The Time and Place for Nature in Drug Discovery. JACS Au 2 (11) (2022)
Shenaz B Bunally, Christopher N Luscombe, Robert J Young
Using Physicochemical Measurements to Influence Better Compound Design. SLAS discovery : advancing life sciences R & D 24 (8) (2020)
Elizabeth Fullam, Robert J Young
Physicochemical properties and Mycobacterium tuberculosis transporters: keys to efficacious antitubercular drugs? RSC medicinal chemistry 12 (1) (2020)
John Liddle, Jonathan P Hutchinson, Semra Kitchen, Paul Rowland, Margarete Neu, Ted Cecconie, Duncan S Holmes, Emma Jones, Justyna Korczynska, Despoina Koumantou, Jonathan D Lea, Leng Nickels, Michelle Pemberton, Alex Phillipou, Jessica L Schneck, Hester Sheehan, Christopher P Tinworth, Iain Uings, Justyna Wojno-Picon, Robert J Young, Efstratios Stratikos
Targeting the Regulatory Site of ER Aminopeptidase 1 Leads to the Discovery of a Natural Product Modulator of Antigen Presentation. Journal of medicinal chemistry 63 (6) (2020)
Jennifer A Borthwick, Carlos Alemparte, Ian Wall, Benjamin C Whitehurst, Argyrides Argyrou, Glenn A Burley, Paco de Dios-Anton, Laura Guijarro, Maria Candida Monteiro, Fatima Ortega, Colin J Suckling, Julia Castro Pichel, Mónica Cacho, Robert J Young
Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase Inhibitors: Expeditious Reconstruction of Suboptimal Hits into a Series with Potent in Vivo Activity. Journal of medicinal chemistry 63 (5) (2020)
Ruben Gomez-Sanchez, Stephen Besley, Zoe Zeliku, Robert J Young
Method Development and Application of an Accelerated Solution Stability Screen for Drug Discovery. SLAS discovery : advancing life sciences R & D 25 (10) (2020)
Christopher P Tinworth, Robert J Young
Facts, Patterns, and Principles in Drug Discovery: Appraising the Rule of 5 with Measured Physicochemical Data. Journal of medicinal chemistry 63 (18) (2020)
Graham L Simpson, Sophie M Bertrand, Jennifer A Borthwick, Nino Campobasso, Julien Chabanet, Susan Chen, Julia Coggins, Josh Cottom, Siegfried B Christensen, Helen C Dawson, Helen L Evans, Andrew N Hobbs, Xuan Hong, Biju Mangatt, Jordi Munoz-Muriedas, Allen Oliff, Donghui Qin, Paul Scott-Stevens, Paris Ward, Yoshiaki Washio, Jingsong Yang, Robert J Young
Identification and Optimization of Novel Small c-Abl Kinase Activators Using Fragment and HTS Methodologies. Journal of medicinal chemistry 62 (4) (2019)
Yvett Sosa, Roman Deniskin, I J Frame, Matthew S Steiginga, Deepak Bandyopadhyay, Todd L Graybill, Lorena A Kallal, Michael T Ouellette, Andrew J Pope, Katherine L Widdowson, Robert J Young, Myles H Akabas
Identification via a Parallel Hit Progression Strategy of Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit Plasmodium falciparum Parasite Proliferation. ACS infectious diseases 5 (10) (2019)
Robert J Young, Paul D Leeson
Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations. Journal of medicinal chemistry 61 (15) (2018)
Peter D Craggs, Stephane Mouilleron, Martin Rejzek, Cesira de Chiara, Robert J Young, Robert A Field, Argyrides Argyrou, Luiz Pedro Sorio de Carvalho
The Mechanism of Acetyl Transfer Catalyzed by Mycobacterium tuberculosis GlmU. Biochemistry 57 (24) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Robert J Young