Michael M Desai

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 41

Top Topics

Body Composition

Genome Wide Association

Respiratory Syndrome Coronavirus

Angiotensin Converting Enzyme

Top Venues

bioRxiv : the preprint server for biology

Proceedings of the National Academy of Sciences of the United States of America

Science (New York, N.Y.)

This page only lists publications with an associated author ORCID identifier.

Publications

Matthew J Melissa, Michael M Desai
A dynamical limit to evolutionary adaptation. Proceedings of the National Academy of Sciences of the United States of America 121 (4) (2024)
Matthew J Melissa, Michael M Desai
A dynamical limit to evolutionary adaptation. Proceedings of the National Academy of Sciences of the United States of America 121 (4) (2024)
Berk A Alpay, Michael M Desai
Effects of selection stringency on the outcomes of directed evolution. bioRxiv : the preprint server for biology (2024)
Matthew J Melissa, Michael M Desai
A dynamical limit to evolutionary adaptation. Proceedings of the National Academy of Sciences of the United States of America 121 (4) (2024)
Matthew J Melissa, Michael M Desai
A dynamical limit to evolutionary adaptation. Proceedings of the National Academy of Sciences of the United States of America 121 (4) (2024)
Berk A Alpay, Michael M Desai
Effects of selection stringency on the outcomes of directed evolution. bioRxiv : the preprint server for biology (2024)
Matthew J Melissa, Michael M Desai
A dynamical limit to evolutionary adaptation. Proceedings of the National Academy of Sciences of the United States of America 121 (4) (2024)
Berk A Alpay, Michael M Desai
Effects of selection stringency on the outcomes of directed evolution. bioRxiv : the preprint server for biology (2024)
Thomas Dupic, Angela M Phillips, Michael M Desai
Protein sequence landscapes are not so simple: on reference-free versus reference-based inference. bioRxiv : the preprint server for biology (2024)
Berk A Alpay, Michael M Desai
Effects of selection stringency on the outcomes of directed evolution. bioRxiv : the preprint server for biology (2024)
Thomas Dupic, Angela M Phillips, Michael M Desai
Protein sequence landscapes are not so simple: on reference-free versus reference-based inference. bioRxiv : the preprint server for biology (2024)
Matthew J Melissa, Michael M Desai
A dynamical limit to evolutionary adaptation. Proceedings of the National Academy of Sciences of the United States of America 121 (4) (2024)
Vivian Chen, Milo S Johnson, Lucas Hérissant, Parris T Humphrey, David C Yuan, Yuping Li, Atish Agarwala, Samuel B Hoelscher, Dmitri A Petrov, Michael M Desai, Gavin Sherlock
Evolution of haploid and diploid populations reveals common, strong, and variable pleiotropic effects in non-home environments. eLife 12 (2023)
Alief Moulana, Thomas Dupic, Angela M Phillips, Jeffrey Chang, Anne A Roffler, Allison J Greaney, Tyler N Starr, Jesse D Bloom, Michael M Desai
The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution. eLife 12 (2023)
Alief Moulana, Thomas Dupic, Angela M Phillips, Jeffrey Chang, Anne A Roffler, Allison J Greaney, Tyler N Starr, Jesse D Bloom, Michael M Desai
The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution. eLife 12 (2023)
Angela M Phillips, Daniel P Maurer, Caelan Brooks, Thomas Dupic, Aaron G Schmidt, Michael M Desai
Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody. eLife 12 (2023)
Milo S Johnson, Gautam Reddy, Michael M Desai
Epistasis and evolution: recent advances and an outlook for prediction. BMC biology 21 (1) (2023)
Angela M Phillips, Daniel P Maurer, Caelan Brooks, Thomas Dupic, Aaron G Schmidt, Michael M Desai
Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody. eLife 12 (2023)
Alief Moulana, Thomas Dupic, Angela M Phillips, Jeffrey Chang, Anne A Roffler, Allison J Greaney, Tyler N Starr, Jesse D Bloom, Michael M Desai
The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution. eLife 12 (2023)
Alief Moulana, Thomas Dupic, Angela M Phillips, Jeffrey Chang, Anne A Roffler, Allison J Greaney, Tyler N Starr, Jesse D Bloom, Michael M Desai
The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution. eLife 12 (2023)
Matthew J Melissa, Michael M Desai
A dynamical limit to evolutionary adaptation. bioRxiv : the preprint server for biology (2023)
Angela M Phillips, Daniel P Maurer, Caelan Brooks, Thomas Dupic, Aaron G Schmidt, Michael M Desai
Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody. eLife 12 (2023)
Angela M Phillips, Daniel P Maurer, Caelan Brooks, Thomas Dupic, Aaron G Schmidt, Michael M Desai
Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody. eLife 12 (2023)
Alief Moulana, Thomas Dupic, Angela M Phillips, Jeffrey Chang, Anne A Roffler, Allison J Greaney, Tyler N Starr, Jesse D Bloom, Michael M Desai
The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution. eLife 12 (2023)
Alief Moulana, Thomas Dupic, Angela M Phillips, Jeffrey Chang, Anne A Roffler, Allison J Greaney, Tyler N Starr, Jesse D Bloom, Michael M Desai
The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution. eLife 12 (2023)
Alief Moulana, Thomas Dupic, Angela M Phillips, Jeffrey Chang, Anne A Roffler, Allison J Greaney, Tyler N Starr, Jesse D Bloom, Michael M Desai
The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution. eLife 12 (2023)
Angela M Phillips, Daniel P Maurer, Caelan Brooks, Thomas Dupic, Aaron G Schmidt, Michael M Desai
Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody. eLife 12 (2023)
Christopher W Baker, Alex N Nguyen Ba, Yekaterina Shulgina, José I Rojas Echenique, Michael M Desai
Idiosyncratic epistasis leads to global fitness-correlated trends. Science (New York, N.Y.) 376 (6593) (2022)
Jiseon Min, Misha Gupta, Michael M Desai, Daniel B Weissman
Spatial structure alters the site frequency spectrum produced by hitchhiking. Genetics 222 (3) (2022)
Milo S Johnson, Michael M Desai
Mutational robustness changes during long-term adaptation in laboratory budding yeast populations. eLife 11 (2022)
Matthew J Melissa, Benjamin H Good, Daniel S Fisher, Michael M Desai
Population genetics of polymorphism and divergence in rapidly evolving populations. Genetics 221 (4) (2022)
Alex N Nguyen Ba, Katherine R Lawrence, Artur Rego-Costa, Shreyas Gopalakrishnan, Daniel Temko, Franziska Michor, Michael M Desai
Barcoded bulk QTL mapping reveals highly polygenic and epistatic architecture of complex traits in yeast. eLife 11 (2022)
Alief Moulana, Thomas Dupic, Angela M Phillips, Jeffrey Chang, Serafina Nieves, Anne A Roffler, Allison J Greaney, Tyler N Starr, Jesse D Bloom, Michael M Desai
Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA.1. Nature communications 13 (1) (2022)
Christopher W Baker, Angela M Phillips, Alex N Nguyen Ba, Michael M Desai
Dynamics and variability in the pleiotropic effects of adaptation in laboratory budding yeast populations. eLife 10 (2021)
Milo S Johnson, Shreyas Gopalakrishnan, Juhee Goyal, Megan E Dillingham, Christopher W Bakerlee, Parris T Humphrey, Tanush Jagdish, Elizabeth R Jerison, Katya Kosheleva, Katherine R Lawrence, Jiseon Min, Alief Moulana, Angela M Phillips, Julia C Piper, Ramya Purkanti, Artur Rego-Costa, Michael J McDonald, Alex N Nguyen Ba, Michael M Desai
Phenotypic and molecular evolution across 10,000 generations in laboratory budding yeast populations. eLife 10 (2021)
Angela M Phillips, Katherine R Lawrence, Alief Moulana, Thomas Dupic, Jeffrey Chang, Milo S Johnson, Ivana Cvijovic, Thierry Mora, Aleksandra M Walczak, Michael M Desai
Binding affinity landscapes constrain the evolution of broadly neutralizing anti-influenza antibodies. eLife 10 (2021)
Gautam Reddy, Michael M Desai
Global epistasis emerges from a generic model of a complex trait. eLife 10 (2021)
Milo S Johnson, Alena Martsul, Sergey Kryazhimskiy, Michael M Desai
Higher-fitness yeast genotypes are less robust to deleterious mutations. Science (New York, N.Y.) 366 (6464) (2020)
Elizabeth R Jerison, Alex N Nguyen Ba, Michael M Desai, Sergey Kryazhimskiy
Chance and necessity in the pleiotropic consequences of adaptation for budding yeast. Nature ecology & evolution 4 (4) (2020)
José I Rojas Echenique, Sergey Kryazhimskiy, Alex N Nguyen Ba, Michael M Desai
Modular epistasis and the compensatory evolution of gene deletion mutants. PLoS genetics 15 (2) (2019)
Elizabeth R Jerison, Sergey Kryazhimskiy, James Kameron Mitchell, Joshua S Bloom, Leonid Kruglyak, Michael M Desai
Genetic variation in adaptability and pleiotropy in budding yeast. eLife 6 (2017)