Michael T Laub

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 42

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

mBio

eLife

Massachusetts Institute of Technology

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Massachusetts Institute of Technology Jul 01 2016

United States

Professor :: Biology

Howard Hughes Medical Institute

United States

Investigator

Massachusetts Institute of Technology - Jun 30 2016

United States

Associate Professor :: Biology

Howard Hughes Medical Institute

United States

Early Career Scientist

Publications

David Ding, Ada Y Shaw, Sam Sinai, Nathan Rollins, Noam Prywes, David F Savage, Michael T Laub, Debora S Marks
Protein design using structure-based residue preferences. Nature communications 15 (1) (2024)
David Ding, Ada Y Shaw, Sam Sinai, Nathan Rollins, Noam Prywes, David F Savage, Michael T Laub, Debora S Marks
Protein design using structure-based residue preferences. Nature communications 15 (1) (2024)
Chantal K Guegler, Gabriella I C Teodoro, Sriram Srikant, Keerthana Chetlapalli, Christopher R Doering, Dia A Ghose, Michael T Laub
A phage-encoded RNA-binding protein inhibits the antiviral activity of a toxin-antitoxin system. Nucleic acids research 52 (3) (2024)
David Ding, Ada Y Shaw, Sam Sinai, Nathan Rollins, Noam Prywes, David F Savage, Michael T Laub, Debora S Marks
Protein design using structure-based residue preferences. Nature communications 15 (1) (2024)
Chantal K Guegler, Gabriella I C Teodoro, Sriram Srikant, Keerthana Chetlapalli, Christopher R Doering, Dia A Ghose, Michael T Laub
A phage-encoded RNA-binding protein inhibits the antiviral activity of a toxin-antitoxin system. Nucleic acids research 52 (3) (2024)
Chantal K Guegler, Gabriella I C Teodoro, Sriram Srikant, Keerthana Chetlapalli, Christopher R Doering, Dia A Ghose, Michael T Laub
A phage-encoded RNA-binding protein inhibits the antiviral activity of a toxin-antitoxin system. Nucleic acids research 52 (3) (2024)
Christopher N Vassallo, Christopher R Doering, Megan L Littlehale, Gabriella I C Teodoro, Michael T Laub
Author Correction: A functional selection reveals previously undetected anti-phage defence systems in the E. coli pangenome. Nature microbiology (2024)
David Ding, Ada Y Shaw, Sam Sinai, Nathan Rollins, Noam Prywes, David F Savage, Michael T Laub, Debora S Marks
Protein design using structure-based residue preferences. Nature communications 15 (1) (2024)
Idan Frumkin, Michael T Laub
Selection of a de novo gene that can promote survival of Escherichia coli by modulating protein homeostasis pathways. Nature ecology & evolution (2023)
Chantal K Guegler, Gabriella I C Teodoro, Sriram Srikant, Keerthana Chetlapalli, Christopher R Doering, Dia A Ghose, Michael T Laub
A phage-encoded RNA-binding protein inhibits the antiviral activity of a toxin-antitoxin system. Nucleic acids research (2023)
Ross D Jones, Yili Qian, Katherine Ilia, Benjamin Wang, Michael T Laub, Domitilla Del Vecchio, Ron Weiss
Author Correction: Robust and tunable signal processing in mammalian cells via engineered covalent modification cycles. Nature communications 14 (1) (2023)
Dia A Ghose, Kaitlyn E Przydzial, Emily M Mahoney, Amy E Keating, Michael T Laub
Marginal specificity in protein interactions constrains evolution of a paralogous family. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Dia A Ghose, Kaitlyn E Przydzial, Emily M Mahoney, Amy E Keating, Michael T Laub
Marginal specificity in protein interactions constrains evolution of a paralogous family. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Dia A Ghose, Kaitlyn E Przydzial, Emily M Mahoney, Amy E Keating, Michael T Laub
Marginal specificity in protein interactions constrains evolution of a paralogous family. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Aoshu Zhong, Xiaofang Jiang, Alison B Hickman, Katherine Klier, Gabriella I C Teodoro, Fred Dyda, Michael T Laub, Gisela Storz
Toxic antiphage defense proteins inhibited by intragenic antitoxin proteins. Proceedings of the National Academy of Sciences of the United States of America 120 (31) (2023)
Dia A Ghose, Kaitlyn E Przydzial, Emily M Mahoney, Amy E Keating, Michael T Laub
Marginal specificity in protein interactions constrains evolution of a paralogous family. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Dia A Ghose, Kaitlyn E Przydzial, Emily M Mahoney, Amy E Keating, Michael T Laub
Marginal specificity in protein interactions constrains evolution of a paralogous family. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Dia A Ghose, Kaitlyn E Przydzial, Emily M Mahoney, Amy E Keating, Michael T Laub
Marginal specificity in protein interactions constrains evolution of a paralogous family. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Dia A Ghose, Kaitlyn E Przydzial, Emily M Mahoney, Amy E Keating, Michael T Laub
Marginal specificity in protein interactions constrains evolution of a paralogous family. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Isabel Nocedal, Michael T Laub
Ancestral reconstruction of duplicated signaling proteins reveals the evolution of signaling specificity. eLife 11 (2022)
Kevin Gozzi, Ngat T Tran, Joshua W Modell, Tung B K Le, Michael T Laub
Prophage-like gene transfer agents promote Caulobacter crescentus survival and DNA repair during stationary phase. PLoS biology 20 (11) (2022)
David Ding, Anna G Green, Boyuan Wang, Thuy-Lan Vo Lite, Eli N Weinstein, Debora S Marks, Michael T Laub
Co-evolution of interacting proteins through non-contacting and non-specific mutations. Nature ecology & evolution 6 (5) (2022)
Sriram Srikant, Chantal K Guegler, Michael T Laub
The evolution of a counter-defense mechanism in a virus constrains its host range. eLife 11 (2022)
Ross D Jones, Yili Qian, Katherine Ilia, Benjamin Wang, Michael T Laub, Domitilla Del Vecchio, Ron Weiss
Robust and tunable signal processing in mammalian cells via engineered covalent modification cycles. Nature communications 13 (1) (2022)
Negar Shahsavari, Boyuan Wang, Yu Imai, Miho Mori, Sangkeun Son, Libang Liang, Nils Böhringer, Sylvie Manuse, Michael F Gates, Madeleine Morrissette, Rachel Corsetti, Josh L Espinoza, Chris L Dupont, Michael T Laub, Kim Lewis
A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP. mBio 13 (3) (2022)
Tong Zhang, Hedvig Tamman, Kyo Coppieters 't Wallant, Tatsuaki Kurata, Michele LeRoux, Sriram Srikant, Tetiana Brodiazhenko, Albinas Cepauskas, Ariel Talavera, Chloe Martens, Gemma Catherine Atkinson, Vasili Hauryliuk, Abel Garcia-Pino, Michael T Laub
Direct activation of a bacterial innate immune system by a viral capsid protein. Nature 612 (7938) (2022)
Michele LeRoux, Sriram Srikant, Gabriella I C Teodoro, Tong Zhang, Megan L Littlehale, Shany Doron, Mohsen Badiee, Anthony K L Leung, Rotem Sorek, Michael T Laub
The DarTG toxin-antitoxin system provides phage defence by ADP-ribosylating viral DNA. Nature microbiology 7 (7) (2022)
Christopher N Vassallo, Christopher R Doering, Megan L Littlehale, Gabriella I C Teodoro, Michael T Laub
A functional selection reveals previously undetected anti-phage defence systems in the E. coli pangenome. Nature microbiology 7 (10) (2022)
Mary K Thompson, Isabel Nocedal, Peter H Culviner, Tong Zhang, Kevin R Gozzi, Michael T Laub
Escherichia coli SymE is a DNA-binding protein that can condense the nucleoid. Molecular microbiology 117 (4) (2022)
Gabriel T Filsinger, Timothy M Wannier, Felix B Pedersen, Isaac D Lutz, Julie Zhang, Devon A Stork, Anik Debnath, Kevin Gozzi, Helene Kuchwara, Verena Volf, Stan Wang, Xavier Rios, Christopher J Gregg, Marc J Lajoie, Seth L Shipman, John Aach, Michael T Laub, George M Church
Characterizing the portability of phage-encoded homologous recombination proteins. Nature chemical biology 17 (4) (2021)
Peter H Culviner, Isabel Nocedal, Sarah M Fortune, Michael T Laub
Global Analysis of the Specificities and Targets of Endoribonucleases from Escherichia coli Toxin-Antitoxin Systems. mBio 12 (5) (2021)
Monica S Guo, Ryo Kawamura, Megan L Littlehale, John F Marko, Michael T Laub
High-resolution, genome-wide mapping of positive supercoiling in chromosomes. eLife 10 (2021)
Benjamin X Wang, Kyle C Cady, Gerardo C Oyarce, Katharina Ribbeck, Michael T Laub
Two-Component Signaling Systems Regulate Diverse Virulence-Associated Traits in Pseudomonas aeruginosa. Applied and environmental microbiology 87 (11) (2021)
Peter H Culviner, Chantal K Guegler, Michael T Laub
A Simple, Cost-Effective, and Robust Method for rRNA Depletion in RNA-Sequencing Studies. mBio 11 (2) (2020)
Mathilde Guzzo, Lennice K Castro, Christopher R Reisch, Monica S Guo, Michael T Laub
A CRISPR Interference System for Efficient and Rapid Gene Knockdown in Caulobacter crescentus. mBio 11 (1) (2020)
Thuy-Lan Vo Lite, Robert A Grant, Isabel Nocedal, Megan L Littlehale, Monica S Guo, Michael T Laub
Uncovering the basis of protein-protein interaction specificity with a combinatorially complete library. eLife 9 (2020)
James A Kraemer, Allen G Sanderlin, Michael T Laub
The Stringent Response Inhibits DNA Replication Initiation in E. coli by Modulating Supercoiling of oriC. mBio 10 (4) (2019)
Philip Davidson, Rory Eutsey, Brendan Redler, N Luisa Hiller, Michael T Laub, Dannie Durand
Flexibility and constraint: Evolutionary remodeling of the sporulation initiation pathway in Firmicutes. PLoS genetics 14 (9) (2018)
Boyuan Wang, Peng Dai, David Ding, Amanda Del Rosario, Robert A Grant, Bradley L Pentelute, Michael T Laub
Affinity-based capture and identification of protein effectors of the growth regulator ppGpp. Nature chemical biology 15 (2) (2018)
Anjana Badrinarayanan, Tung B K Le, Jan-Hendrik Spille, Ibrahim I Cisse, Michael T Laub
Global analysis of double-strand break processing reveals in vivo properties of the helicase-nuclease complex AddAB. PLoS genetics 13 (5) (2017)
Leonor García-Bayona, Monica S Guo, Michael T Laub
Contact-dependent killing by Caulobacter crescentus via cell surface-associated, glycine zipper proteins. eLife 6 (2017)
Tung B K Le, Michael T Laub
Transcription rate and transcript length drive formation of chromosomal interaction domain boundaries. The EMBO journal 35 (14) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Michael T Laub