Michel Goedert

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 33

Top Topics

Amyotrophic Lateral Sclerosis

High Resolution

Electron Microscopy

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Acta neuropathologica communications

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Chao Qi, Sofia Lövestam, Alexey G Murzin, Sew Peak-Chew, Catarina Franco, Marika Bogdani, Caitlin Latimer, Jill R Murrell, Patrick W Cullinane, Zane Jaunmuktane, Thomas D Bird, Bernardino Ghetti, Sjors H W Scheres, Michel Goedert
Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W. bioRxiv : the preprint server for biology (2024)
Chao Qi, Sofia Lövestam, Alexey G Murzin, Sew Peak-Chew, Catarina Franco, Marika Bogdani, Caitlin Latimer, Jill R Murrell, Patrick W Cullinane, Zane Jaunmuktane, Thomas D Bird, Bernardino Ghetti, Sjors H W Scheres, Michel Goedert
Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W. bioRxiv : the preprint server for biology (2024)
Chao Qi, Masato Hasegawa, Masaki Takao, Motoko Sakai, Mayasuki Sasaki, Masashi Mizutani, Akio Akagi, Yasushi Iwasaki, Hiroaki Miyahara, Mari Yoshida, Sjors H W Scheres, Michel Goedert
Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy. Acta neuropathologica communications 11 (1) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold. bioRxiv : the preprint server for biology (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Chao Qi, Masato Hasegawa, Masaki Takao, Motoko Sakai, Mayasuki Sasaki, Masashi Mizutani, Akio Akagi, Yasushi Iwasaki, Hiroaki Miyahara, Mari Yoshida, Sjors H W Scheres, Michel Goedert
Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy. Acta neuropathologica communications 11 (1) (2023)
Chao Qi, Masato Hasegawa, Masaki Takao, Motoko Sakai, Mayasuki Sasaki, Masashi Mizutani, Akio Akagi, Yasushi Iwasaki, Hiroaki Miyahara, Mari Yoshida, Sjors H W Scheres, Michel Goedert
Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy. Acta neuropathologica communications 11 (1) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Chao Qi, Masato Hasegawa, Masaki Takao, Motoko Sakai, Mayasuki Sasaki, Masashi Mizutani, Akio Akagi, Yasushi Iwasaki, Hiroaki Miyahara, Mari Yoshida, Sjors H W Scheres, Michel Goedert
Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy. Acta neuropathologica communications 11 (1) (2023)
Aamir S Mukadam, Lauren V C Miller, Annabel E Smith, Marina Vaysburd, Siri Aastedatter Sakya, Sophie A I Sanford, Sophie Keeling, Benjamin J Tuck, Taxiarchis Katsinelos, Christopher Green, Lise R Skov, Sanne Simone Kaalund, Stian Foss, Keith Mayes, Kevin O'Connell, Mark Wing, Claire Knox, Jessica Banbury, Edward Avezov, James Benedict Rowe, Michel Goedert, Jan Terje Andersen, Leo C James, William A McEwan
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models. Science (New York, N.Y.) 379 (6639) (2023)
Chao Qi, Masato Hasegawa, Masaki Takao, Motoko Sakai, Mayasuki Sasaki, Masashi Mizutani, Akio Akagi, Yasushi Iwasaki, Hiroaki Miyahara, Mari Yoshida, Sjors H W Scheres, Michel Goedert
Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy. Acta neuropathologica communications 11 (1) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold. bioRxiv : the preprint server for biology (2023)
Manuel Schweighauser, Alexey G Murzin, Jennifer Macdonald, Isabelle Lavenir, R Anthony Crowther, Sjors H W Scheres, Michel Goedert
Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau. Acta neuropathologica communications 11 (1) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold. bioRxiv : the preprint server for biology (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Aamir S Mukadam, Lauren V C Miller, Annabel E Smith, Marina Vaysburd, Siri Aastedatter Sakya, Sophie A I Sanford, Sophie Keeling, Benjamin J Tuck, Taxiarchis Katsinelos, Christopher Green, Lise R Skov, Sanne Simone Kaalund, Stian Foss, Keith Mayes, Kevin O'Connell, Mark Wing, Claire Knox, Jessica Banbury, Edward Avezov, James Benedict Rowe, Michel Goedert, Jan Terje Andersen, Leo C James, William A McEwan
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models. Science (New York, N.Y.) 379 (6639) (2023)
Sjors H W Scheres, Benjamin Ryskeldi-Falcon, Michel Goedert
Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids. Nature 621 (7980) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Yang Yang, Alexey G Murzin, Sew Peak-Chew, Catarina Franco, Holly J Garringer, Kathy L Newell, Bernardino Ghetti, Michel Goedert, Sjors H W Scheres
Cryo-EM structures of Aβ40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy. Acta neuropathologica communications 11 (1) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Sofia Lövestam, David Li, Jane L Wagstaff, Abhay Kotecha, Dari Kimanius, Stephen H McLaughlin, Alexey G Murzin, Stefan M V Freund, Michel Goedert, Sjors H W Scheres
Disease-specific tau filaments assemble via polymorphic intermediates. Nature (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Yang Yang, Yang Shi, Manuel Schweighauser, Xianjun Zhang, Abhay Kotecha, Alexey G Murzin, Holly J Garringer, Patrick W Cullinane, Yuko Saito, Tatiana M Foroud, Thomas Treharne Warner, Kazuko Hasegawa, Ruben Vidal, Shigeo Murayama, Tamas Revesz, Bernardino F Ghetti, Masato Hasegawa, Tammaryn Lashley, Sjors H W Scheres, Michel Goedert
Structures of α-synuclein filaments from human brains with Lewy pathology. Nature 610 (7933) (2022)
Sofia Lövestam, Fujiet Adrian Koh, Bart van Knippenberg, Abhay Kotecha, Alexey G Murzin, Michel Goedert, Sjors H W Scheres
Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy. eLife 11 (2022)
Yang Yang, Diana Arseni, Wenjuan Zhang, Melissa Huang, Sofia Lövestam, Manuel Schweighauser, Abhay Kotecha, Alexey G Murzin, Sew Y Peak-Chew, Jennifer Macdonald, Isabelle Lavenir, Holly J Garringer, Ellen Gelpí, Kathy L Newell, Gábor G Kovács, Ruben Vidal, Bernardino F Ghetti, Benjamin Ryskeldi-Falcon, Sjors H W Scheres, Michel Goedert
Cryo-EM structures of amyloid-β 42 filaments from human brains. Science (New York, N.Y.) 375 (6577) (2022)
Manuel Schweighauser, Diana Arseni, Mehtap Bacioglu, Melissa Huang, Sofia Lövestam, Yang Shi, Yang Yang, Wenjuan Zhang, Abhay Kotecha, Holly J Garringer, Ruben Vidal, Grace I Hallinan, Kathy L Newell, Airi Tarutani, Shigeo Murayama, Masayuki Miyazaki, Yuko Saito, Mari Yoshida, Kazuko Hasegawa, Tammaryn Lashley, Tamas Revesz, Gábor G Kovács, John van Swieten, Masaki Takao, Masato Hasegawa, Bernardino F Ghetti, Maria Grazia Spillantini, Benjamin Ryskeldi-Falcon, Alexey G Murzin, Michel Goedert, Sjors H W Scheres
Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature 605 (7909) (2022)
Michel Goedert
Cryo-EM structures of τ filaments from human brain. Essays in biochemistry (2021)
Sofia Lövestam, Manuel Schweighauser, Tomoyasu Matsubara, Shigeo Murayama, Taisuke Tomita, Takashi Ando, Kazuko Hasegawa, Mari Yoshida, Airi Tarutani, Masato Hasegawa, Michel Goedert, Sjors H W Scheres
Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy. FEBS open bio 11 (4) (2021)
Yang Shi, Wenjuan Zhang, Yang Yang, Alexey G Murzin, Benjamin Falcon, Abhay Kotecha, Mike van Beers, Airi Tarutani, Fuyuki Kametani, Holly J Garringer, Ruben Vidal, Grace I Hallinan, Tammaryn Lashley, Yuko Saito, Shigeo Murayama, Mari Yoshida, Hidetomo Tanaka, Akiyoshi Kakita, Takeshi Ikeuchi, Andrew C Robinson, David M A Mann, Gábor G Kovács, Tamas Revesz, Bernardino F Ghetti, Masato Hasegawa, Michel Goedert, Sjors H W Scheres
Structure-based classification of tauopathies. Nature 598 (7880) (2021)
Manuel Schweighauser, Yang Shi, Airi Tarutani, Fuyuki Kametani, Alexey G Murzin, Bernardino F Ghetti, Tomoyasu Matsubara, Taisuke Tomita, Takashi Ando, Kazuko Hasegawa, Shigeo Murayama, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Structures of α-synuclein filaments from multiple system atrophy. Nature 585 (7825) (2020)
Benjamin Ryskeldi-Falcon, Wenjuan Zhang, Manuel Schweighauser, Alexey G Murzin, Ruben Vidal, Holly J Garringer, Bernardino F Ghetti, Sjors H W Scheres, Michel Goedert
Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold. Acta neuropathologica 136 (5) (2018)