Sjors H W Scheres (Sjors Hw Scheres)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 81

Top Venues

Nature

Proceedings of the National Academy of Sciences of the United States of America

eLife

bioRxiv : the preprint server for biology

MRC Laboratory of Molecular Biology

Universiteit Utrecht (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

MRC Laboratory of Molecular Biology Jun 01 2010

United Kingdom

Group Leader :: Structural Studies

Centro Nacional de Biotecnología Jun 01 2003 - May 31 2010

Spain

Post-doc :: Biocomputing Unit

Education History

Universiteit Utrecht Jun 01 1998 - May 31 2003

Netherlands

PHD :: Chemistry

Publications

Manuel Schweighauser, Yang Shi, Alexey G Murzin, Holly J Garringer, Ruben Vidal, Jill R Murrell, M Elena Erro, Harro Seelaar, Isidro Ferrer, John C van Swieten, Bernardino Ghetti, Sjors H W Scheres, Michel Goedert
Novel tau filament folds in individuals with MAPT mutations P301L and P301T. bioRxiv : the preprint server for biology (2024)
Alister Burt, Bogdan Toader, Rangana Warshamanage, Andriko von Kügelgen, Euan Pyle, Jasenko Zivanov, Dari Kimanius, Tanmay A M Bharat, Sjors H W Scheres
An image processing pipeline for electron cryo-tomography in RELION-5. FEBS open bio (2024)
Gerard J Kleywegt, Paul D Adams, Sarah Jane Butcher, Catherine L Lawson, Alexis L Rohou, Peter B Rosenthal, Sriram Subramaniam, Andriy Kryshtafovych, Sanja Abbott, Philip R Baldwin, John M Berrisford, Gérard Bricogne, Preeti Choudhary, Tristan I Croll, Radostin Danev, Sai J Ganesan, Timothy Grant, Aleksandras Gutmanas, Richard Henderson, J Bernard Heymann, Juha T Huiskonen, Andrei Istrate, Takayuki Kato, Gabriel C Lander, Shee-Mei Lok, Steven J Ludtke, Garib N Murshudov, Ryan Pye, Grigore D Pintilie, Jane S Richardson, Carsten Sachse, Osman Salih, Sjors H W Scheres, Gunnar F Schröder, Carlos Oscar S Sorzano, Scott M Stagg, Zhe Wang, Rangana Warshamanage, John D Westbrook, Martyn David Winn, Jasmine Y Young, Stephen K Burley, Jeffrey C Hoch, Genji Kurisu, Kyle L Morris, Ardan Patwardhan, Sameer Velankar
Community recommendations on cryoEM data archiving and validation. IUCrJ (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Gerard J Kleywegt, Paul D Adams, Sarah Jane Butcher, Catherine L Lawson, Alexis L Rohou, Peter B Rosenthal, Sriram Subramaniam, Andriy Kryshtafovych, Sanja Abbott, Philip R Baldwin, John M Berrisford, Gérard Bricogne, Preeti Choudhary, Tristan I Croll, Radostin Danev, Sai J Ganesan, Timothy Grant, Aleksandras Gutmanas, Richard Henderson, J Bernard Heymann, Juha T Huiskonen, Andrei Istrate, Takayuki Kato, Gabriel C Lander, Shee-Mei Lok, Steven J Ludtke, Garib N Murshudov, Ryan Pye, Grigore D Pintilie, Jane S Richardson, Carsten Sachse, Osman Salih, Sjors H W Scheres, Gunnar F Schröder, Carlos Oscar S Sorzano, Scott M Stagg, Zhe Wang, Rangana Warshamanage, John D Westbrook, Martyn David Winn, Jasmine Y Young, Stephen K Burley, Jeffrey C Hoch, Genji Kurisu, Kyle L Morris, Ardan Patwardhan, Sameer Velankar
Community recommendations on cryoEM data archiving and validation. IUCrJ 11 (Pt 2) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature 628 (8007) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Dari Kimanius, Kiarash Jamali, Max E Wilkinson, Sofia Lövestam, Vaithish Velazhahan, Takanori Nakane, Sjors H W Scheres
Data-driven regularization lowers the size barrier of cryo-EM structure determination. Nature methods 21 (7) (2024)
Chao Qi, Sofia Lövestam, Alexey G Murzin, Sew Peak-Chew, Catarina Franco, Marika Bogdani, Caitlin Latimer, Jill R Murrell, Patrick W Cullinane, Zane Jaunmuktane, Thomas D Bird, Bernardino Ghetti, Sjors H W Scheres, Michel Goedert
Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W. bioRxiv : the preprint server for biology (2024)
Gerard J Kleywegt, Paul D Adams, Sarah Jane Butcher, Catherine L Lawson, Alexis L Rohou, Peter B Rosenthal, Sriram Subramaniam, Andriy Kryshtafovych, Sanja Abbott, Philip R Baldwin, John M Berrisford, Gérard Bricogne, Preeti Choudhary, Tristan I Croll, Radostin Danev, Sai J Ganesan, Timothy Grant, Aleksandras Gutmanas, Richard Henderson, J Bernard Heymann, Juha T Huiskonen, Andrei Istrate, Takayuki Kato, Gabriel C Lander, Shee-Mei Lok, Steven J Ludtke, Garib N Murshudov, Ryan Pye, Grigore D Pintilie, Jane S Richardson, Carsten Sachse, Osman Salih, Sjors H W Scheres, Gunnar F Schröder, Carlos Oscar S Sorzano, Scott M Stagg, Zhe Wang, Rangana Warshamanage, John D Westbrook, Martyn David Winn, Jasmine Y Young, Stephen K Burley, Jeffrey C Hoch, Genji Kurisu, Kyle L Morris, Ardan Patwardhan, Sameer Velankar
Community recommendations on cryoEM data archiving and validation. IUCrJ (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Dari Kimanius, Kiarash Jamali, Max E Wilkinson, Sofia Lövestam, Vaithish Velazhahan, Takanori Nakane, Sjors H W Scheres
Data-driven regularization lowers the size barrier of cryo-EM structure determination. Nature methods 21 (7) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Gerard J Kleywegt, Paul D Adams, Sarah Jane Butcher, Catherine L Lawson, Alexis L Rohou, Peter B Rosenthal, Sriram Subramaniam, Andriy Kryshtafovych, Sanja Abbott, Philip R Baldwin, John M Berrisford, Gérard Bricogne, Preeti Choudhary, Tristan I Croll, Radostin Danev, Sai J Ganesan, Timothy Grant, Aleksandras Gutmanas, Richard Henderson, J Bernard Heymann, Juha T Huiskonen, Andrei Istrate, Takayuki Kato, Gabriel C Lander, Shee-Mei Lok, Steven J Ludtke, Garib N Murshudov, Ryan Pye, Grigore D Pintilie, Jane S Richardson, Carsten Sachse, Osman Salih, Sjors H W Scheres, Gunnar F Schröder, Carlos Oscar S Sorzano, Scott M Stagg, Zhe Wang, Rangana Warshamanage, John D Westbrook, Martyn David Winn, Jasmine Y Young, Stephen K Burley, Jeffrey C Hoch, Genji Kurisu, Kyle L Morris, Ardan Patwardhan, Sameer Velankar
Community recommendations on cryoEM data archiving and validation. IUCrJ 11 (Pt 2) (2024)
Manuel Schweighauser, Yang Shi, Alexey G Murzin, Holly J Garringer, Ruben Vidal, Jill R Murrell, M Elena Erro, Harro Seelaar, Isidro Ferrer, John C van Swieten, Bernardino Ghetti, Sjors H W Scheres, Michel Goedert
Novel tau filament folds in individuals with MAPT mutations P301L and P301T. bioRxiv : the preprint server for biology (2024)
Dari Kimanius, Kiarash Jamali, Max E Wilkinson, Sofia Lövestam, Vaithish Velazhahan, Takanori Nakane, Sjors H W Scheres
Data-driven regularization lowers the size barrier of cryo-EM structure determination. Nature methods 21 (7) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature 628 (8007) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature 628 (8007) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Chao Qi, Sofia Lövestam, Alexey G Murzin, Sew Peak-Chew, Catarina Franco, Marika Bogdani, Caitlin Latimer, Jill R Murrell, Patrick W Cullinane, Zane Jaunmuktane, Thomas D Bird, Bernardino Ghetti, Sjors H W Scheres, Michel Goedert
Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W. bioRxiv : the preprint server for biology (2024)
Gerard J Kleywegt, Paul D Adams, Sarah Jane Butcher, Catherine L Lawson, Alexis L Rohou, Peter B Rosenthal, Sriram Subramaniam, Andriy Kryshtafovych, Sanja Abbott, Philip R Baldwin, John M Berrisford, Gérard Bricogne, Preeti Choudhary, Tristan I Croll, Radostin Danev, Sai J Ganesan, Timothy Grant, Aleksandras Gutmanas, Richard Henderson, J Bernard Heymann, Juha T Huiskonen, Andrei Istrate, Takayuki Kato, Gabriel C Lander, Shee-Mei Lok, Steven J Ludtke, Garib N Murshudov, Ryan Pye, Grigore D Pintilie, Jane S Richardson, Carsten Sachse, Osman Salih, Sjors H W Scheres, Gunnar F Schröder, Carlos Oscar S Sorzano, Scott M Stagg, Zhe Wang, Rangana Warshamanage, John D Westbrook, Martyn David Winn, Jasmine Y Young, Stephen K Burley, Jeffrey C Hoch, Genji Kurisu, Kyle L Morris, Ardan Patwardhan, Sameer Velankar
Community recommendations on cryoEM data archiving and validation. IUCrJ 11 (Pt 2) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature 628 (8007) (2024)
Dari Kimanius, Kiarash Jamali, Max E Wilkinson, Sofia Lövestam, Vaithish Velazhahan, Takanori Nakane, Sjors H W Scheres
Data-driven regularization lowers the size barrier of cryo-EM structure determination. Nature methods (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature 628 (8007) (2024)
Sjors H W Scheres
Alzheimer's plaques and tangles revealed by 3D microscopy. Nature 631 (8022) (2024)
Johannes Schwab, Dari Kimanius, Alister Burt, Tom Dendooven, Sjors H W Scheres
DynaMight: estimating molecular motions with improved reconstruction from cryo-EM images. Nature methods (2024)
Sjors H W Scheres
Alzheimer's plaques and tangles revealed by 3D microscopy. Nature 631 (8022) (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature (2024)
Gerard J Kleywegt, Paul D Adams, Sarah Jane Butcher, Catherine L Lawson, Alexis L Rohou, Peter B Rosenthal, Sriram Subramaniam, Andriy Kryshtafovych, Sanja Abbott, Philip R Baldwin, John M Berrisford, Gérard Bricogne, Preeti Choudhary, Tristan I Croll, Radostin Danev, Sai J Ganesan, Timothy Grant, Aleksandras Gutmanas, Richard Henderson, J Bernard Heymann, Juha T Huiskonen, Andrei Istrate, Takayuki Kato, Gabriel C Lander, Shee-Mei Lok, Steven J Ludtke, Garib N Murshudov, Ryan Pye, Grigore D Pintilie, Jane S Richardson, Carsten Sachse, Osman Salih, Sjors H W Scheres, Gunnar F Schröder, Carlos Oscar S Sorzano, Scott M Stagg, Zhe Wang, Rangana Warshamanage, John D Westbrook, Martyn David Winn, Jasmine Y Young, Stephen K Burley, Jeffrey C Hoch, Genji Kurisu, Kyle L Morris, Ardan Patwardhan, Sameer Velankar
Community recommendations on cryoEM data archiving and validation. IUCrJ 11 (Pt 2) (2024)
Manuel Schweighauser, Yang Shi, Alexey G Murzin, Holly J Garringer, Ruben Vidal, Jill R Murrell, M Elena Erro, Harro Seelaar, Isidro Ferrer, John C van Swieten, Bernardino Ghetti, Sjors H W Scheres, Michel Goedert
Novel tau filament folds in individuals with MAPT mutations P301L and P301T. bioRxiv : the preprint server for biology (2024)
Sjors H W Scheres
Alzheimer's plaques and tangles revealed by 3D microscopy. Nature (2024)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres
Automated model building and protein identification in cryo-EM maps. Nature 628 (8007) (2024)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold. bioRxiv : the preprint server for biology (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Tom Dendooven, Ziguo Zhang, Jing Yang, Stephen H McLaughlin, Johannes Schwab, Sjors H W Scheres, Stanislau Yatskevich, David Barford
Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere. Science advances 9 (30) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold. bioRxiv : the preprint server for biology (2023)
Yang Yang, Wenjuan Zhang, Alexey G Murzin, Manuel Schweighauser, Melissa Huang, Sofia Lövestam, Sew Y Peak-Chew, Takashi Saito, Takaomi C Saido, Jennifer Macdonald, Isabelle Lavenir, Bernardino Ghetti, Caroline Graff, Amit Kumar, Agneta Nordberg, Michel Goedert, Sjors H W Scheres
Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains. Acta neuropathologica 145 (3) (2023)
Yang Yang, Wenjuan Zhang, Alexey G Murzin, Manuel Schweighauser, Melissa Huang, Sofia Lövestam, Sew Y Peak-Chew, Takashi Saito, Takaomi C Saido, Jennifer Macdonald, Isabelle Lavenir, Bernardino Ghetti, Caroline Graff, Amit Kumar, Agneta Nordberg, Michel Goedert, Sjors H W Scheres
Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains. Acta neuropathologica 145 (3) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold. bioRxiv : the preprint server for biology (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Airi Tarutani, Sofia Lövestam, Xianjun Zhang, Abhay Kotecha, Andrew C Robinson, David M A Mann, Yuko Saito, Shigeo Murayama, Taisuke Tomita, Michel Goedert, Sjors H W Scheres, Masato Hasegawa
Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration. FEBS open bio (2023)
Sjors H W Scheres, Benjamin Ryskeldi-Falcon, Michel Goedert
Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids. Nature 621 (7980) (2023)
Yang Yang, Wenjuan Zhang, Alexey G Murzin, Manuel Schweighauser, Melissa Huang, Sofia Lövestam, Sew Y Peak-Chew, Takashi Saito, Takaomi C Saido, Jennifer Macdonald, Isabelle Lavenir, Bernardino Ghetti, Caroline Graff, Amit Kumar, Agneta Nordberg, Michel Goedert, Sjors H W Scheres
Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains. Acta neuropathologica 145 (3) (2023)
Yang Yang, Wenjuan Zhang, Alexey G Murzin, Manuel Schweighauser, Melissa Huang, Sofia Lövestam, Sew Y Peak-Chew, Takashi Saito, Takaomi C Saido, Jennifer Macdonald, Isabelle Lavenir, Bernardino Ghetti, Caroline Graff, Amit Kumar, Agneta Nordberg, Michel Goedert, Sjors H W Scheres
Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains. Acta neuropathologica (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Sofia Lövestam, David Li, Jane L Wagstaff, Abhay Kotecha, Dari Kimanius, Stephen H McLaughlin, Alexey G Murzin, Stefan M V Freund, Michel Goedert, Sjors H W Scheres
Disease-specific tau filaments assemble via polymorphic intermediates. Nature (2023)
Yang Yang, Wenjuan Zhang, Alexey G Murzin, Manuel Schweighauser, Melissa Huang, Sofia Lövestam, Sew Y Peak-Chew, Takashi Saito, Takaomi C Saido, Jennifer Macdonald, Isabelle Lavenir, Bernardino Ghetti, Caroline Graff, Amit Kumar, Agneta Nordberg, Michel Goedert, Sjors H W Scheres
Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains. Acta neuropathologica 145 (3) (2023)
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Jasenko Zivanov, Joaquin Otón, Zunlong Ke, Andriko von Kügelgen, Euan Pyle, Kun Qu, Dustin Morado, Daniel Castaño-Díez, Giulia Zanetti, Tanmay A M Bharat, John A G Briggs, Sjors H W Scheres
A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0. eLife 11 (2022)
Yang Yang, Yang Shi, Manuel Schweighauser, Xianjun Zhang, Abhay Kotecha, Alexey G Murzin, Holly J Garringer, Patrick W Cullinane, Yuko Saito, Tatiana M Foroud, Thomas Treharne Warner, Kazuko Hasegawa, Ruben Vidal, Shigeo Murayama, Tamas Revesz, Bernardino F Ghetti, Masato Hasegawa, Tammaryn Lashley, Sjors H W Scheres, Michel Goedert
Structures of α-synuclein filaments from human brains with Lewy pathology. Nature 610 (7933) (2022)
Sofia Lövestam, Fujiet Adrian Koh, Bart van Knippenberg, Abhay Kotecha, Alexey G Murzin, Michel Goedert, Sjors H W Scheres
Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy. eLife 11 (2022)
Saskia E Bakker, Julien Bergeron, Alok Bharadwaj, David Bhella, Per Bullough, Pak-Lee Chau, René A W Frank, Arjen J Jakobi, Agnel Praveen Joseph, Werner Kühlbrandt, Indrajit Lahiri, Rebbekah Menday, Stephen P Muench, Mark Nakasone, Dmitry Nerukh, Giulia Paris, Christopher J Russo, Helen R Saibil, Sjors H W Scheres, Vidhi Sehrawat, Archna R Shah, Andrea Thorn, José Luis Vilas, Giulia Zanetti
Map/model validation and machine learning in EM: general discussion. Faraday discussions 240 (0) (2022)
Yang Yang, Diana Arseni, Wenjuan Zhang, Melissa Huang, Sofia Lövestam, Manuel Schweighauser, Abhay Kotecha, Alexey G Murzin, Sew Y Peak-Chew, Jennifer Macdonald, Isabelle Lavenir, Holly J Garringer, Ellen Gelpí, Kathy L Newell, Gábor G Kovács, Ruben Vidal, Bernardino F Ghetti, Benjamin Ryskeldi-Falcon, Sjors H W Scheres, Michel Goedert
Cryo-EM structures of amyloid-β 42 filaments from human brains. Science (New York, N.Y.) 375 (6577) (2022)
Manuel Schweighauser, Diana Arseni, Mehtap Bacioglu, Melissa Huang, Sofia Lövestam, Yang Shi, Yang Yang, Wenjuan Zhang, Abhay Kotecha, Holly J Garringer, Ruben Vidal, Grace I Hallinan, Kathy L Newell, Airi Tarutani, Shigeo Murayama, Masayuki Miyazaki, Yuko Saito, Mari Yoshida, Kazuko Hasegawa, Tammaryn Lashley, Tamas Revesz, Gábor G Kovács, John van Swieten, Masaki Takao, Masato Hasegawa, Bernardino F Ghetti, Maria Grazia Spillantini, Benjamin Ryskeldi-Falcon, Alexey G Murzin, Michel Goedert, Sjors H W Scheres
Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature 605 (7909) (2022)
Sofia Lövestam, Sjors H W Scheres
High-throughput cryo-EM structure determination of amyloids. Faraday discussions 240 (0) (2022)
Sofia Lövestam, Manuel Schweighauser, Tomoyasu Matsubara, Shigeo Murayama, Taisuke Tomita, Takashi Ando, Kazuko Hasegawa, Mari Yoshida, Airi Tarutani, Masato Hasegawa, Michel Goedert, Sjors H W Scheres
Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy. FEBS open bio 11 (4) (2021)
Yang Shi, Wenjuan Zhang, Yang Yang, Alexey G Murzin, Benjamin Falcon, Abhay Kotecha, Mike van Beers, Airi Tarutani, Fuyuki Kametani, Holly J Garringer, Ruben Vidal, Grace I Hallinan, Tammaryn Lashley, Yuko Saito, Shigeo Murayama, Mari Yoshida, Hidetomo Tanaka, Akiyoshi Kakita, Takeshi Ikeuchi, Andrew C Robinson, David M A Mann, Gábor G Kovács, Tamas Revesz, Bernardino F Ghetti, Masato Hasegawa, Michel Goedert, Sjors H W Scheres
Structure-based classification of tauopathies. Nature 598 (7880) (2021)
Zunlong Ke, Joaquin Otón, Kun Qu, Mirko Cortese, Vojtech Zila, Lesley McKeane, Takanori Nakane, Jasenko Zivanov, Christopher John Neufeldt, Berati Cerikan, John M Lu, Julia Peukes, Xiaoli Xiong, Hans-Georg Kräusslich, Sjors H W Scheres, Ralf F W Bartenschlager, John A G Briggs
Structures and distributions of SARS-CoV-2 spike proteins on intact virions. Nature 588 (7838) (2020)
Massimo Kube, Fabian Kohler, Elija Feigl, Baki Nagel-Yüksel, Elena M Willner, Jonas J Funke, Thomas Gerling, Pierre Stömmer, Maximilian N Honemann, Thomas G Martin, Sjors H W Scheres, Hendrik Dietz
Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution. Nature communications 11 (1) (2020)
Wenjuan Zhang, Airi Tarutani, Kathy L Newell, Alexey G Murzin, Tomoyasu Matsubara, Benjamin Falcon, Ruben Vidal, Holly J Garringer, Yang Shi, Takeshi Ikeuchi, Shigeo Murayama, Bernardino F Ghetti, Masato Hasegawa, Michel Goedert, Sjors H W Scheres
Novel tau filament fold in corticobasal degeneration. Nature 580 (7802) (2020)
Takanori Nakane, Abhay Kotecha, Andrija Sente, Greg McMullan, Simonas Masiulis, Patricia M G E Brown, Ioana T Grigoras, Lina Malinauskaite, Tomas Malinauskas, Jonas Miehling, Tomasz Uchański, Lingbo Yu, Dimple Karia, Evgeniya V Pechnikova, Erwin de Jong, Jeroen Keizer, Maarten Bischoff, Jamie McCormack, Peter Tiemeijer, Steven W Hardwick, Dimitri Y Chirgadze, Garib Murshudov, A Radu Aricescu, Sjors H W Scheres
Single-particle cryo-EM at atomic resolution. Nature 587 (7832) (2020)
Manuel Schweighauser, Yang Shi, Airi Tarutani, Fuyuki Kametani, Alexey G Murzin, Bernardino F Ghetti, Tomoyasu Matsubara, Taisuke Tomita, Takashi Ando, Kazuko Hasegawa, Shigeo Murayama, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goedert
Structures of α-synuclein filaments from multiple system atrophy. Nature 585 (7825) (2020)
Xiaoli Xiong, Kun Qu, Katarzyna A Ciazynska, Myra Hosmillo, Andrew P Carter, Soraya Ebrahimi, Zunlong Ke, Sjors H W Scheres, Laura Bergamaschi, Guinevere L Grice, Ying Zhang, null null, James A Nathan, Stephen Baker, Leo C James, Helen E Baxendale, Ian Goodfellow, Rainer Doffinger, John A G Briggs
A thermostable, closed SARS-CoV-2 spike protein trimer. Nature structural & molecular biology 27 (10) (2020)
Ruben Hervas, Michael J Rau, Younshim Park, Wenjuan Zhang, Alexey G Murzin, James A J Fitzpatrick, Sjors H W Scheres, Kausik Si
Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila. Science (New York, N.Y.) 367 (6483) (2020)
Samuel E Lacey, Shaoda He, Sjors H W Scheres, Andrew P Carter
Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule. eLife 8 (2019)
Wenjuan Zhang, Benjamin Falcon, Alexey G Murzin, Juan Fan, R Anthony Crowther, Michel Goedert, Sjors H W Scheres
Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. eLife 8 (2019)
Takanori Nakane, Dari Kimanius, Erik Lindahl, Sjors H W Scheres
Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION. eLife 7 (2018)
Jasenko Zivanov, Takanori Nakane, Björn O Forsberg, Dari Kimanius, Wim J H Hagen, Erik Lindahl, Sjors H W Scheres
New tools for automated high-resolution cryo-EM structure determination in RELION-3. eLife 7 (2018)
Benjamin Ryskeldi-Falcon, Wenjuan Zhang, Manuel Schweighauser, Alexey G Murzin, Ruben Vidal, Holly J Garringer, Bernardino F Ghetti, Sjors H W Scheres, Michel Goedert
Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold. Acta neuropathologica 136 (5) (2018)
Cornelius Gati, Artem Stetsenko, Dirk J Slotboom, Sjors H W Scheres, Albert Guskov
The structural basis of proton driven zinc transport by ZntB. Nature communications 8 (1) (2017)
Yini Li, Mengying Zhou, Qi Hu, Xiao-Chen Bai, Weiyun Huang, Sjors H W Scheres, Yigong Shi
Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme. Proceedings of the National Academy of Sciences of the United States of America 114 (7) (2017)
Rafael Fernandez-Leiro, Julian Conrad, Ji-Chun Yang, Stefan M V Freund, Sjors H W Scheres, Meindert Hugo Lamers
Self-correcting mismatches during high-fidelity DNA replication. Nature structural & molecular biology 24 (2) (2017)
Andreas Boland, Thomas G Martin, Ziguo Zhang, Jing Yang, Xiao-Chen Bai, Leifu Chang, Sjors H W Scheres, David Barford
Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution. Nature structural & molecular biology 24 (4) (2017)
Jan Löwe, Shaoda He, Sjors H W Scheres, Christos G Savva
X-ray and cryo-EM structures of monomeric and filamentous actin-like protein MamK reveal changes associated with polymerization. Proceedings of the National Academy of Sciences of the United States of America 113 (47) (2016)
Thomas G Martin, Tanmay A M Bharat, Andreas C Joerger, Xiao-Chen Bai, Florian Praetorius, Alan R Fersht, Hendrik Dietz, Sjors H W Scheres
Design of a molecular support for cryo-EM structure determination. Proceedings of the National Academy of Sciences of the United States of America 113 (47) (2016)
Dari Kimanius, Björn O Forsberg, Sjors H W Scheres, Erik Lindahl
Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2. eLife 5 (2016)
Rafael Fernandez-Leiro, Julian Conrad, Sjors H W Scheres, Meindert H Lamers
cryo-EM structures of the E. coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and τ. eLife 4 (2015)
Xiao-chen Bai, Eeson Rajendra, Guanghui Yang, Yigong Shi, Sjors H W Scheres
Sampling the conformational space of the catalytic subunit of human γ-secretase. eLife 4 (2015)

Sjors H W Scheres.css-eqlu8i{font-size:small;padding-left:4px;} (Sjors Hw Scheres)

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Sjors H W Scheres (Sjors Hw Scheres)