Mohamed I Saad

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 18

Top Venues

Cancer science

Proceedings of the National Academy of Sciences of the United States of America

Scientifica

Stem cells translational medicine

Monash University (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

Monash University Sep 30 2015 - May 21 2019

Australia

PHD :: Hudson Institute of Medical Research

Medical Research Institute Alexandria University

Egypt

MSC :: Biochemistry

Alexandria University Faculty of Pharmacy

Egypt

BSC

Publications

Mohammad Alanazi, Teresa Weng, Louise McLeod, Linden J Gearing, Julian A Smith, Beena Kumar, Mohamed I Saad, Brendan J Jenkins
Cytosolic DNA sensor AIM2 promotes KRAS-driven lung cancer independent of inflammasomes. Cancer science 115 (6) (2024)
Mohammad Alanazi, Teresa Weng, Louise McLeod, Linden J Gearing, Julian A Smith, Beena Kumar, Mohamed I Saad, Brendan J Jenkins
Cytosolic DNA sensor AIM2 promotes KRAS-driven lung cancer independent of inflammasomes. Cancer science 115 (6) (2024)
Mohammad Alanazi, Teresa Weng, Louise McLeod, Linden J Gearing, Julian A Smith, Beena Kumar, Mohamed I Saad, Brendan J Jenkins
Cytosolic DNA sensor AIM2 promotes KRAS-driven lung cancer independent of inflammasomes. Cancer science 115 (6) (2024)
Mohammad Alanazi, Teresa Weng, Louise McLeod, Linden J Gearing, Julian A Smith, Beena Kumar, Mohamed I Saad, Brendan J Jenkins
Cytosolic DNA sensor AIM2 promotes KRAS-driven lung cancer independent of inflammasomes. Cancer science 115 (6) (2024)
Mohammad Alanazi, Teresa Weng, Louise McLeod, Linden J Gearing, Julian A Smith, Beena Kumar, Mohamed I Saad, Brendan J Jenkins
Cytosolic DNA sensor AIM2 promotes KRAS-driven lung cancer independent of inflammasomes. Cancer science (2024)
Mohamed I Saad, Brendan J Jenkins
The Protease ADAM17 at the Crossroads of Disease: Revisiting its Significance in Inflammation, Cancer, and Beyond. The FEBS journal (2023)
Mohamed I Saad, Teresa Weng, Joanne Lundy, Linden J Gearing, Alison C West, Christopher M Harpur, Mohammad Alanazi, Christopher Hodges, Daniel Croagh, Beena Kumar, Irit Sagi, Stefan Rose-John, Brendan J Jenkins
Blockade of the protease ADAM17 ameliorates experimental pancreatitis. Proceedings of the National Academy of Sciences of the United States of America 119 (42) (2022)
Saleela M Ruwanpura, Louise McLeod, Lovisa F Dousha, Huei J Seow, Alison C West, Alice J West, Teresa Weng, Mohammad Alanazi, Martin I MacDonald, Paul T King, Philip G Bardin, Cem Gabay, Dennis M Klinman, Steven Bozinovski, Ross Vlahos, Gary P Anderson, Stefan Rose-John, Mohamed I Saad, Brendan J Jenkins
Cross-talk between IL-6 trans-signaling and AIM2 inflammasome/IL-1β axes bridge innate immunity and epithelial apoptosis to promote emphysema. Proceedings of the National Academy of Sciences of the United States of America 119 (36) (2022)
Amanda Vannitamby, Mohamed I Saad, Christian Aloe, Hao Wang, Beena Kumar, Ross Vlahos, Stavros Selemidis, Louis Irving, Daniel Steinfort, Brendan J Jenkins, Steven Bozinovski
Aspirin-Triggered Resolvin D1 Reduces Proliferation and the Neutrophil to Lymphocyte Ratio in a Mutant KRAS-Driven Lung Adenocarcinoma Model. Cancers 13 (13) (2021)
Ruby E Dawson, Virginie Deswaerte, Alison C West, Ke Tang, Alice J West, Jesse J Balic, Linden J Gearing, Mohamed I Saad, Liang Yu, Yonghui Wu, Prithi S Bhathal, Beena Kumar, Jayati T Chakrabarti, Yana Zavros, Hiroko Oshima, Dennis M Klinman, Masanobu Oshima, Patrick Boon-Ooi Tan, Brendan J Jenkins
STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis. Gut (2021)
Sultan Alhayyani, Louise McLeod, Alison C West, Jesse J Balic, Christopher Hodges, Liang Yu, Julian A Smith, Zdenka Prodanovic, Steven Bozinovski, Beena Kumar, Saleela M Ruwanpura, Mohamed I Saad, Brendan J Jenkins
Oncogenic dependency on STAT3 serine phosphorylation in KRAS mutant lung cancer. Oncogene (2021)
Mohamed I Saad, Louise McLeod, Christopher Hodges, Ross Vlahos, Stefan Rose-John, Saleela Ruwanpura, Brendan J Jenkins
ADAM17 Deficiency Protects against Pulmonary Emphysema. American journal of respiratory cell and molecular biology 64 (2) (2021)
Mohamed I Saad, Sultan Alhayyani, Louise McLeod, Liang Yu, Mohammad Alanazi, Virginie Deswaerte, Ke Tang, Thierry Jarde, Julian A Smith, Zdenka Prodanovic, Michelle D Tate, Jesse J Balic, D Neil Watkins, Jason E Cain, Steven Bozinovski, Elizabeth Algar, Tomohiro Kohmoto, Hiromichi Ebi, Walter Ferlin, Christoph Garbers, Saleela Ruwanpura, Irit Sagi, Stefan Rose-John, Brendan J Jenkins
ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer. EMBO molecular medicine 11 (4) (2020)
Jesse J Balic, Daniel J Garama, Mohamed I Saad, Liang Yu, Alison C West, Alice J West, Thaleia Livis, Prithi S Bhathal, Daniel J Gough, Brendan J Jenkins
Serine-Phosphorylated STAT3 Promotes Tumorigenesis via Modulation of RNA Polymerase Transcriptional Activity. Cancer research 79 (20) (2019)
Jean L Tan, Sin N Lau, Bryan Leaw, Hong P T Nguyen, Lois A Salamonsen, Mohamed I Saad, Siow T Chan, Dandan Zhu, Mirja Krause, Carla Kim, William Sievert, Euan M Wallace, Rebecca Lim
Amnion Epithelial Cell-Derived Exosomes Restrict Lung Injury and Enhance Endogenous Lung Repair. Stem cells translational medicine 7 (2) (2018)
Mervat Y Hanafi, Mohamed I Saad, Taha M Abdelkhalek, Moustafa M Saleh, Maher A Kamel
In Utero Nutritional Manipulation Provokes Dysregulated Adipocytokines Production in F1 Offspring in Rats. Scientifica 2016 (2016)
Mohamed I Saad, Taha M Abdelkhalek, Moustafa M Saleh, Maher A Kamel, Mina Youssef, Shady H Tawfik, Helena Dominguez
Insights into the molecular mechanisms of diabetes-induced endothelial dysfunction: focus on oxidative stress and endothelial progenitor cells. Endocrine 50 (3) (2015)
Mervat Y Hanafi, Moustafa M Saleh, Mohamed I Saad, Taha M Abdelkhalek, Maher A Kamel
Transgenerational effects of obesity and malnourishment on diabetes risk in F2 generation. Molecular and cellular biochemistry 412 (1-2) (2015)

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Publication Activity (10 Years)

Top Topics

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Mohamed I Saad