Neil Johnson

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 17

Top Topics

Epstein Barr Virus

Dna Damage Response

Top Venues

Nature communications

Molecular cancer therapeutics

This page only lists publications with an associated author ORCID identifier.

Publications

Fumiaki Ito, Ziyuan Li, Leonid Minakhin, Gurushankar Chandramouly, Mrityunjay Tyagi, Robert Betsch, John J Krais, Bernadette Taberi, Umeshkumar Vekariya, Marissa L Calbert, Tomasz Skorski, Neil Johnson, Xiaojiang S Chen, Richard T Pomerantz
Structural basis for a Polθ helicase small-molecule inhibitor revealed by cryo-EM. Nature communications 15 (1) (2024)
William Fried, Mrityunjay Tyagi, Leonid Minakhin, Gurushankar Chandramouly, Taylor N Tredinnick, Mercy Ramanjulu, William Auerbacher, Marissa L Calbert, Timur Rusanov, Trung Hoang, Nikita Borisonnik, Robert Betsch, John J Krais, Yifan Wang, Umeshkumar M Vekariya, John Gordon, George Morton, Tatiana Kent, Tomasz Skorski, Neil Johnson, Wayne Childers, Xiaojiang S Chen, Richard T Pomerantz
Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors. Nature communications 15 (1) (2024)
Jason S Wasserman, Bulat Faezov, Kishan R Patel, Alison N Kurimchak, Seren M Palacio, David J Glass, Holly Fowle, Brennan C McEwan, Qifang Xu, Ziran Zhao, Lauren E Cressey, Neil Johnson, James S Duncan, Arminja N Kettenbach, Roland L Dunbrack, Xavier Graña
FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs. Nature communications 15 (1) (2024)
William Fried, Mrityunjay Tyagi, Leonid Minakhin, Gurushankar Chandramouly, Taylor N Tredinnick, Mercy Ramanjulu, William Auerbacher, Marissa L Calbert, Timur Rusanov, Trung Hoang, Nikita Borisonnik, Robert Betsch, John J Krais, Yifan Wang, Umeshkumar M Vekariya, John Gordon, George Morton, Tatiana Kent, Tomasz Skorski, Neil Johnson, Wayne Childers, Xiaojiang S Chen, Richard T Pomerantz
Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors. Nature communications 15 (1) (2024)
William Fried, Mrityunjay Tyagi, Leonid Minakhin, Gurushankar Chandramouly, Taylor N Tredinnick, Mercy Ramanjulu, William Auerbacher, Marissa L Calbert, Timur Rusanov, Trung Hoang, Nikita Borisonnik, Robert Betsch, John J Krais, Yifan Wang, Umeshkumar M Vekariya, John Gordon, George Morton, Tatiana Kent, Tomasz Skorski, Neil Johnson, Wayne Childers, Xiaojiang S Chen, Richard T Pomerantz
Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors. Nature communications 15 (1) (2024)
Jason S Wasserman, Bulat Faezov, Kishan R Patel, Alison N Kurimchak, Seren M Palacio, David J Glass, Holly Fowle, Brennan C McEwan, Qifang Xu, Ziran Zhao, Lauren E Cressey, Neil Johnson, James S Duncan, Arminja N Kettenbach, Roland L Dunbrack, Xavier Graña
FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs. Nature communications 15 (1) (2024)
Jason S Wasserman, Bulat Faezov, Kishan R Patel, Alison N Kurimchak, Seren M Palacio, David J Glass, Holly Fowle, Brennan C McEwan, Qifang Xu, Ziran Zhao, Lauren E Cressey, Neil Johnson, James S Duncan, Arminja N Kettenbach, Roland L Dunbrack, Xavier Graña
FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs. Nature communications 15 (1) (2024)
Fumiaki Ito, Ziyuan Li, Leonid Minakhin, Gurushankar Chandramouly, Mrityunjay Tyagi, Robert Betsch, John J Krais, Bernadette Taberi, Umeshkumar Vekariya, Marissa L Calbert, Tomasz Skorski, Neil Johnson, Xiaojiang S Chen, Richard T Pomerantz
Structural basis for a Polθ helicase small-molecule inhibitor revealed by cryo-EM. Nature communications 15 (1) (2024)
Jason S Wasserman, Bulat Faezov, Kishan R Patel, Alison N Kurimchak, Seren M Palacio, David J Glass, Holly Fowle, Brennan C McEwan, Qifang Xu, Ziran Zhao, Lauren E Cressey, Neil Johnson, James S Duncan, Arminja N Kettenbach, Roland L Dunbrack, Xavier Graña
FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs. Nature communications 15 (1) (2024)
William Fried, Mrityunjay Tyagi, Leonid Minakhin, Gurushankar Chandramouly, Taylor N Tredinnick, Mercy Ramanjulu, William Auerbacher, Marissa L Calbert, Timur Rusanov, Trung Hoang, Nikita Borisonnik, Robert Betsch, John J Krais, Yifan Wang, Umeshkumar M Vekariya, John Gordon, George Morton, Tatiana Kent, Tomasz Skorski, Neil Johnson, Wayne Childers, Xiaojiang S Chen, Richard T Pomerantz
Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors. Nature communications 15 (1) (2024)
Jason S Wasserman, Bulat Faezov, Kishan R Patel, Alison N Kurimchak, Seren M Palacio, David J Glass, Holly Fowle, Brennan C McEwan, Qifang Xu, Ziran Zhao, Lauren E Cressey, Neil Johnson, James S Duncan, Arminja N Kettenbach, Roland L Dunbrack, Xavier Graña
FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs. Nature communications 15 (1) (2024)
Jason S Wasserman, Bulat Faezov, Kishan R Patel, Alison N Kurimchak, Seren M Palacio, David J Glass, Holly Fowle, Brennan C McEwan, Qifang Xu, Ziran Zhao, Lauren E Cressey, Neil Johnson, James S Duncan, Arminja N Kettenbach, Roland L Dunbrack, Xavier Graña
FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs. Nature communications 15 (1) (2024)
William Fried, Mrityunjay Tyagi, Leonid Minakhin, Gurushankar Chandramouly, Taylor N Tredinnick, Mercy Ramanjulu, William Auerbacher, Marissa L Calbert, Timur Rusanov, Trung Hoang, Nikita Borisonnik, Robert Betsch, John J Krais, Yifan Wang, Umeshkumar M Vekariya, John Gordon, George Morton, Tatiana Kent, Tomasz Skorski, Neil Johnson, Wayne Childers, Xiaojiang S Chen, Richard T Pomerantz
Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors. Nature communications 15 (1) (2024)
Fumiaki Ito, Ziyuan Li, Leonid Minakhin, Gurushankar Chandramouly, Mrityunjay Tyagi, Robert Betsch, John J Krais, Bernadette Taberi, Umeshkumar Vekariya, Marissa L Calbert, Tomasz Skorski, Neil Johnson, Xiaojiang S Chen, Richard T Pomerantz
Structural basis for a Polθ helicase small-molecule inhibitor revealed by cryo-EM. Nature communications 15 (1) (2024)
John J Krais, David J Glass, Ilse Chudoba, Yifan Wang, Wanjuan Feng, Dennis Simpson, Pooja Patel, Zemin Liu, Ryan Neumann-Domer, Robert G Betsch, Andrea J Bernhardy, Alice M Bradbury, Jason Conger, Wei-Ting Yueh, Joseph Nacson, Richard T Pomerantz, Gaorav P Gupta, Joseph R Testa, Neil Johnson
Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities. Nature communications 14 (1) (2023)
Marissa L Calbert, Gurushankar Chandramouly, Clare M Adams, Magali Saez-Ayala, Tatiana Kent, Mrityunjay Tyagi, V S S Abhinav Ayyadevara, Yifan Wang, John J Krais, John Gordon, Jessica Atkins, Monika Maria Toma, Stéphane Betzi, Andrew S Boghossian, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Aaron R Goldman, Nicole Gorman, Ramkrishna Mitra, Wayne E Childers, Xavier Graña, Tomasz Skorski, Neil Johnson, Christian Hurtz, Xavier Morelli, Christine M Eischen, Richard T Pomerantz
4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress. Molecular cancer therapeutics (2023)
John J Krais, Yifan Wang, Pooja Patel, Jayati Basu, Andrea J Bernhardy, Neil Johnson
RNF168-mediated localization of BARD1 recruits the BRCA1-PALB2 complex to DNA damage. Nature communications 12 (1) (2021)