Nico Lachmann

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 36

Top Venues

International journal of molecular sciences

Nature communications

Journal for immunotherapy of cancer

Journal of personalized medicine

Hannover Medical School

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Hannover Medical School Jun 01 2015

Germany

Principle Investigator :: Institute of Experimental Hematology

Publications

Alexander Schnell, Stephanie Tamm, Silke Hedtfeld, Claudio Rodriguez Gonzalez, André Hoerning, Nico Lachmann, Frauke Stanke, Anna-Maria Dittrich, Antje Munder
Analysis of CFTR mRNA and Protein in Peripheral Blood Mononuclear Cells via Quantitative Real-Time PCR and Western Blot. International journal of molecular sciences 25 (12) (2024)
Shifaa M Abdin, Daniela Paasch, Nico Lachmann
CAR macrophages on a fast track to solid tumor therapy. Nature immunology 25 (1) (2024)
Carina Jürgens, Nina Plückebaum, George Liam Ssebyatika, Sarah Beyer, Lucas Mendes-Monteiro, Jiayi Wang, Kai A Kropp, Víctor González-Motos, Lars Steinbrück, Birgit Ritter, Claudio Rodríguez-González, Heike Böning, Eirini Nikolouli, Paul R Kinchington, Nico Lachmann, Daniel P Depledge, Thomas Krey, Abel Viejo-Borbolla
Viral modulation of type II interferon increases T cell adhesion and virus spread. Nature communications 15 (1) (2024)
Shifaa M Abdin, Daniela Paasch, Nico Lachmann
CAR macrophages on a fast track to solid tumor therapy. Nature immunology 25 (1) (2024)
Andrés Augusto Arias, Anna-Lena Neehus, Masato Ogishi, Vincent Meynier, Adam Krebs, Tomi Lazarov, Angela M Lee, Carlos A Arango-Franco, Rui Yang, Julio Orrego, Melissa Corcini Berndt, Julian Rojas, Hailun Li, Darawan Rinchai, Lucia Erazo-Borrás, Ji Eun Han, Bethany Pillay, Khoren Ponsin, Matthieu Chaldebas, Quentin Philippot, Jonathan Bohlen, Jérémie Rosain, Tom Le Voyer, Till Janotte, Krishnajina Amarajeeva, Camille Soudée, Marion Brollo, Katja Wiegmann, Quentin Marquant, Yoann Seeleuthner, Danyel Lee, Candice Lainé, Doreen Kloos, Rasheed Bailey, Paul Bastard, Narelle Keating, Franck Rapaport, Taushif Khan, Marcela Moncada-Vélez, María Camila Carmona, Catalina Obando, Jesús Alvarez, Juan Carlos Cataño, Larry Luber Martínez-Rosado, Juan P Sanchez, Manuela Tejada-Giraldo, Anne-Sophie L'Honneur, María L Agudelo, Lizet J Perez-Zapata, Diana M Arboleda, Juan Fernando Alzate, Felipe Cabarcas, Alejandra Zuluaga, Simon J Pelham, Ensser Armin, Monika Schmidt, Margarita M Velásquez-Lopera, Emmanuelle Jouanguy, Anne Puel, Martin Krönke, Stefano Ghirardello, Alessandro Borghesi, Susanta Pahari, Bertrand Boisson, Stefania Pittaluga, Cindy S Ma, Jean François Emile, Luigi Daniele Notarangelo, Stuart G Tangye, Nico Marr, Nico Lachmann, Hélène Salvator, Larry S Schlesinger, Peng Zhang, Michael S Glickman, Carl F Nathan, Frederic Geissmann, Laurent Abel, Jose Luis Franco, Jacinta Bustamante, Jean Laurent Casanova, Stéphanie Boisson-Dupuis
Tuberculosis in otherwise healthy adults with inherited TNF deficiency. Nature (2024)
Ruba Hammad, Jamal Alzubi, Manuel Rhiel, Kay O Chmielewski, Laura Mosti, Julia Rositzka, Marcel Heugel, Jan Lawrenz, Valentina Pennucci, Birgitta Gläser, Judith Fischer, Axel Schambach, Thomas Moritz, Nico Lachmann, Tatjana I Cornu, Claudio Mussolino, Richard Schäfer, Toni Cathomen
CRISPR-Cas12a for Highly Efficient and Marker-Free Targeted Integration in Human Pluripotent Stem Cells. International journal of molecular sciences 25 (2) (2024)
Ruba Hammad, Jamal Alzubi, Manuel Rhiel, Kay O Chmielewski, Laura Mosti, Julia Rositzka, Marcel Heugel, Jan Lawrenz, Valentina Pennucci, Birgitta Gläser, Judith Fischer, Axel Schambach, Thomas Moritz, Nico Lachmann, Tatjana I Cornu, Claudio Mussolino, Richard Schäfer, Toni Cathomen
CRISPR-Cas12a for Highly Efficient and Marker-Free Targeted Integration in Human Pluripotent Stem Cells. International journal of molecular sciences 25 (2) (2024)
Carina Jürgens, Nina Plückebaum, George Liam Ssebyatika, Sarah Beyer, Lucas Mendes-Monteiro, Jiayi Wang, Kai A Kropp, Víctor González-Motos, Lars Steinbrück, Birgit Ritter, Claudio Rodríguez-González, Heike Böning, Eirini Nikolouli, Paul R Kinchington, Nico Lachmann, Daniel P Depledge, Thomas Krey, Abel Viejo-Borbolla
Viral modulation of type II interferon increases T cell adhesion and virus spread. Nature communications 15 (1) (2024)
Alexander Schnell, Stephanie Tamm, Silke Hedtfeld, Claudio Rodriguez Gonzalez, André Hoerning, Nico Lachmann, Frauke Stanke, Anna-Maria Dittrich, Antje Munder
Analysis of CFTR mRNA and Protein in Peripheral Blood Mononuclear Cells via Quantitative Real-Time PCR and Western Blot. International journal of molecular sciences 25 (12) (2024)
Ruba Hammad, Jamal Alzubi, Manuel Rhiel, Kay O Chmielewski, Laura Mosti, Julia Rositzka, Marcel Heugel, Jan Lawrenz, Valentina Pennucci, Birgitta Gläser, Judith Fischer, Axel Schambach, Thomas Moritz, Nico Lachmann, Tatjana I Cornu, Claudio Mussolino, Richard Schäfer, Toni Cathomen
CRISPR-Cas12a for Highly Efficient and Marker-Free Targeted Integration in Human Pluripotent Stem Cells. International journal of molecular sciences 25 (2) (2024)
Carina Jürgens, Nina Plückebaum, George Liam Ssebyatika, Sarah Beyer, Lucas Mendes-Monteiro, Jiayi Wang, Kai A Kropp, Víctor González-Motos, Lars Steinbrück, Birgit Ritter, Claudio Rodríguez-González, Heike Böning, Eirini Nikolouli, Paul R Kinchington, Nico Lachmann, Daniel P Depledge, Thomas Krey, Abel Viejo-Borbolla
Viral modulation of type II interferon increases T cell adhesion and virus spread. Nature communications 15 (1) (2024)
Carina Jürgens, Nina Plückebaum, George Liam Ssebyatika, Sarah Beyer, Lucas Mendes-Monteiro, Jiayi Wang, Kai A Kropp, Víctor González-Motos, Lars Steinbrück, Birgit Ritter, Claudio Rodríguez-González, Heike Böning, Eirini Nikolouli, Paul R Kinchington, Nico Lachmann, Daniel P Depledge, Thomas Krey, Abel Viejo-Borbolla
Viral modulation of type II interferon increases T cell adhesion and virus spread. Nature communications 15 (1) (2024)
Carina Jürgens, Nina Plückebaum, George Liam Ssebyatika, Sarah Beyer, Lucas Mendes-Monteiro, Jiayi Wang, Kai A Kropp, Víctor González-Motos, Lars Steinbrück, Birgit Ritter, Claudio Rodríguez-González, Heike Böning, Eirini Nikolouli, Paul R Kinchington, Nico Lachmann, Daniel P Depledge, Thomas Krey, Abel Viejo-Borbolla
Viral modulation of type II interferon increases T cell adhesion and virus spread. Nature communications 15 (1) (2024)
Alexander Schnell, Stephanie Tamm, Silke Hedtfeld, Claudio Rodriguez Gonzalez, André Hoerning, Nico Lachmann, Frauke Stanke, Anna-Maria Dittrich, Antje Munder
Analysis of CFTR mRNA and Protein in Peripheral Blood Mononuclear Cells via Quantitative Real-Time PCR and Western Blot. International journal of molecular sciences 25 (12) (2024)
Mania Ackermann, Fawaz Saleh, Shifaa M Abdin, Anna Rafiei Hashtchin, Ingrid Gensch, Julia Golgath, Marco Carvalho Oliveira, Ariane H H Nguyen, Svenja Gaedcke, Arno Fenske, Mi-Sun Jang, Adan C Jirmo, Markus Abeln, Gesine Hansen, Nico Lachmann
Standardized generation of human iPSC-derived hematopoietic organoids and macrophages utilizing a benchtop bioreactor platform under fully defined conditions. Stem cell research & therapy 15 (1) (2024)
Mania Ackermann, Fawaz Saleh, Shifaa M Abdin, Anna Rafiei Hashtchin, Ingrid Gensch, Julia Golgath, Marco Carvalho Oliveira, Ariane H H Nguyen, Svenja Gaedcke, Arno Fenske, Mi-Sun Jang, Adan C Jirmo, Markus Abeln, Gesine Hansen, Nico Lachmann
Standardized generation of human iPSC-derived hematopoietic organoids and macrophages utilizing a benchtop bioreactor platform under fully defined conditions. Stem cell research & therapy 15 (1) (2024)
Carina Jürgens, Nina Plückebaum, George Liam Ssebyatika, Sarah Beyer, Lucas Mendes-Monteiro, Jiayi Wang, Kai A Kropp, Víctor González-Motos, Lars Steinbrück, Birgit Ritter, Claudio Rodríguez-González, Heike Böning, Eirini Nikolouli, Paul R Kinchington, Nico Lachmann, Daniel P Depledge, Thomas Krey, Abel Viejo-Borbolla
Viral modulation of type II interferon increases T cell adhesion and virus spread. Nature communications 15 (1) (2024)
Shifaa M Abdin, Daniela Paasch, Arnold Kloos, Marco Carvalho Oliveira, Mi-Sun Jang, Mania Ackermann, Andriana Stamopoulou, Philipp J Mroch, Christine S Falk, Constantin S von Kaisenberg, Axel Schambach, Michael Heuser, Thomas Moritz, Gesine Hansen, Michael Morgan, Nico Lachmann
Scalable generation of functional human iPSC-derived CAR-macrophages that efficiently eradicate CD19-positive leukemia. Journal for immunotherapy of cancer 11 (12) (2023)
Shifaa M Abdin, Daniela Paasch, Arnold Kloos, Marco Carvalho Oliveira, Mi-Sun Jang, Mania Ackermann, Andriana Stamopoulou, Philipp J Mroch, Christine S Falk, Constantin S von Kaisenberg, Axel Schambach, Michael Heuser, Thomas Moritz, Gesine Hansen, Michael Morgan, Nico Lachmann
Scalable generation of functional human iPSC-derived CAR-macrophages that efficiently eradicate CD19-positive leukemia. Journal for immunotherapy of cancer 11 (12) (2023)
Shifaa M Abdin, Daniela Paasch, Arnold Kloos, Marco Carvalho Oliveira, Mi-Sun Jang, Mania Ackermann, Andriana Stamopoulou, Philipp J Mroch, Christine S Falk, Constantin S von Kaisenberg, Axel Schambach, Michael Heuser, Thomas Moritz, Gesine Hansen, Michael Morgan, Nico Lachmann
Scalable generation of functional human iPSC-derived CAR-macrophages that efficiently eradicate CD19-positive leukemia. Journal for immunotherapy of cancer 11 (12) (2023)
Ian O Shum, Sylvia Merkert, Svitlana Malysheva, Kirsten Jahn, Nico Lachmann, Murielle Verboom, Helge Frieling, Michael Hallensleben, Ulrich Martin
An Improved Protocol for Targeted Differentiation of Primed Human Induced Pluripotent Stem Cells into HLA-G-Expressing Trophoblasts to Enable the Modeling of Placenta-Related Disorders. Cells 12 (16) (2023)
Anna Rafiei Hashtchin, Beate Fehlhaber, Miriam Hetzel, Felix Manstein, Jan Lennart Stalp, Silke Glage, Markus Abeln, Robert Zweigerdt, Antje Munder, Dorothee Viemann, Mania Ackermann, Nico Lachmann
Human iPSC-derived macrophages for efficient Staphylococcus aureus clearance in a murine pulmonary infection model. Blood advances 5 (23) (2022)
Daniela Paasch, Johann Meyer, Andriana Stamopoulou, Daniela Lenz, Johannes Kuehle, Doreen Kloos, Theresa Buchegger, Astrid Holzinger, Christine S Falk, Christina Kloth, Constantin S von Kaisenberg, Hinrich Abken, Axel Schambach, Nico Lachmann, Michael Morgan, Thomas Moritz
Ex Vivo Generation of CAR Macrophages from Hematopoietic Stem and Progenitor Cells for Use in Cancer Therapy. Cells 11 (6) (2022)
Mania Ackermann, Anna Rafiei Hashtchin, Felix Manstein, Marco Carvalho Oliveira, Henning Kempf, Robert Zweigerdt, Nico Lachmann
Continuous human iPSC-macrophage mass production by suspension culture in stirred tank bioreactors. Nature protocols 17 (2) (2022)
Shifaa M Abdin, Daniela Paasch, Michael Morgan, Nico Lachmann
CARs and beyond: tailoring macrophage-based cell therapeutics to combat solid malignancies. Journal for immunotherapy of cancer 9 (8) (2022)
Anna-Lena Neehus, Kunihiko Moriya, Alejandro Nieto-Patlán, Tom Le Voyer, Romain Levy, Ahmet Ozen, Elif Karakoç Aydıner, Safa Barış, Alisan Yildiran, Engin Altundag, Manon Roynard, Kathrin Haake, Mélanie Migaud, Karim Dorgham, Guy Gorochov, Laurent Abel, Nico Lachmann, Figen Doğu, Zehra Şule Haskoloğlu, Erdal İnce, Jamel El Benna, Gulbu Uzel, Ayça Kiykim, Kaan Boztug, Marion Ruth Roderick, Mohammad Shahrooei, Paul A Brogan, Hassan Abolhassani, Gonca Hancioglu, Nima Parvaneh, Alexandre Belot, Aydan İkincioğulları, Jean Laurent Casanova, Anne Puel, Jacinta Bustamante
Impaired respiratory burst contributes to infections in PKCδ-deficient patients. The Journal of experimental medicine 218 (9) (2021)
Dirk Hoffmann, Johanna Sens, Sebastian Brennig, Daniel Brand, Friederike Philipp, Philippe Vollmer Barbosa, Johannes Kuehle, Doris Steinemann, Daniela Lenz, Theresa Buchegger, Michael Morgan, Christine S Falk, Christoph Klein, Nico Lachmann, Axel Schambach
Genetic Correction of IL-10RB Deficiency Reconstitutes Anti-Inflammatory Regulation in iPSC-Derived Macrophages. Journal of personalized medicine 11 (3) (2021)
Suresh Kumar, Johannes Koenig, Andreas Schneider, Fredrik Wermeling, Sanjaykumar Boddul, Sebastian J Theobald, Miriam Vollmer, Doreen Kloos, Nico Lachmann, Frank Klawonn, Siegfried Weiss, Steven R Talbot, André Bleich, Nadine Wenzel, Constantin von Kaisenberg, James Keck, Renata Stripecke
In Vivo Lentiviral Gene Delivery of HLA-DR and Vaccination of Humanized Mice for Improving the Human T and B Cell Immune Reconstitution. Biomedicines 9 (8) (2021)
Ewa Janosz, Miriam Hetzel, Hanna Spielmann, Srinu Tumpara, Charlotte Rossdam, Marc Schwabbauer, Doreen Kloos, Constantin von Kaisenberg, Axel Schambach, Falk F R Büttner, Sabina Janciauskiene, Nico Lachmann, Thomas Moritz
Pulmonary transplantation of alpha-1 antitrypsin (AAT)-transgenic macrophages provides a source of functional human AAT in vivo. Gene therapy 28 (9) (2021)
Julia Dahlke, Juliane W Schott, Philippe Vollmer Barbosa, Denise Klatt, Anton Selich, Nico Lachmann, Michael Morgan, Thomas Moritz, Axel Schambach
Efficient Genetic Safety Switches for Future Application of iPSC-Derived Cell Transplants. Journal of personalized medicine 11 (6) (2021)
Elvira Mass, Nico Lachmann
From macrophage biology to macrophage-based cellular immunotherapies. Gene therapy 28 (9) (2021)
Miriam Hetzel, Mania Ackermann, Nico Lachmann
Beyond "Big Eaters": The Versatile Role of Alveolar Macrophages in Health and Disease. International journal of molecular sciences 22 (7) (2021)
Alexandra Lipus, Ewa Janosz, Mania Ackermann, Miriam Hetzel, Julia Dahlke, Theresa Buchegger, Stephanie Wunderlich, Ulrich Martin, Toni Cathomen, Axel Schambach, Thomas Moritz, Nico Lachmann
Targeted Integration of Inducible Caspase-9 in Human iPSCs Allows Efficient in vitro Clearance of iPSCs and iPSC-Macrophages. International journal of molecular sciences 21 (7) (2020)
Mania Ackermann, Henning Kempf, Miriam Hetzel, Christina Hesse, Anna Rafiei Hashtchin, Kerstin Brinkert, Juliane Wilhelmine Schott, Kathrin Haake, Mark Philipp Kühnel, Silke Glage, Constanca Figueiredo, Danny Jonigk, Katherina Sewald, Axel Schambach, Sabine Wronski, Thomas Moritz, Ulrich Martin, Robert Zweigerdt, Antje Munder, Nico Lachmann
Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections. Nature communications 9 (1) (2018)
Kathrin Haake, Mania Ackermann, Nico Lachmann
Concise Review: Towards the Clinical Translation of Induced Pluripotent Stem Cell-Derived Blood Cells-Ready for Take-Off. Stem cells translational medicine 8 (4) (2018)
Miriam Hetzel, Adele Mucci, Patrick Blank, Ariane Hai Ha Nguyen, Jan Schiller, Olga Halle, Mark-Philipp Kühnel, Sandra Billig, Robert Meineke, Daniel Brand, Vanessa Herder, Wolfgang Baumgärtner, Franz-Christoph Bange, Ralph Goethe, Danny Jonigk, Reinhold Förster, Bernhard Gentner, Jean-Laurent Casanova, Jacinta Bustamante, Axel Schambach, Ulrich Kalinke, Nico Lachmann
Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections. Blood 131 (5) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Nico Lachmann