Nieng Yan

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 57

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

Cell research

Science (New York, N.Y.)

Princeton University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Princeton University Jun 01 2017

United States

Shirley Tilghman Professor :: Molecular Biology

Publications

Jian Huang, Xiao Fan, Xueqin Jin, Chen Lyu, Qinmeng Guo, Tao Liu, Jiaofeng Chen, Amaël Davakan, Philippe Lory, Nieng Yan
Structural basis for human Ca v 3.2 inhibition by selective antagonists. Cell research 34 (6) (2024)
Jian Huang, Xiao Fan, Xueqin Jin, Chen Lyu, Qinmeng Guo, Tao Liu, Jiaofeng Chen, Amaël Davakan, Philippe Lory, Nieng Yan
Structural basis for human Ca v 3.2 inhibition by selective antagonists. Cell research 34 (6) (2024)
Jian Huang, Xiao Fan, Xueqin Jin, Chen Lyu, Qinmeng Guo, Tao Liu, Jiaofeng Chen, Amaël Davakan, Philippe Lory, Nieng Yan
Structural basis for human Ca v 3.2 inhibition by selective antagonists. Cell research (2024)
Zhangqiang Li, Ye Cong, Tong Wu, Tongtong Wang, Xinyao Lou, Xinyu Yang, Nieng Yan
Structural basis for different ω-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels. Cell research (2024)
Zhangqiang Li, Ye Cong, Tong Wu, Tongtong Wang, Xinyao Lou, Xinyu Yang, Nieng Yan
Structural basis for different ω-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels. Cell research (2024)
Zhangqiang Li, Ye Cong, Tong Wu, Tongtong Wang, Xinyao Lou, Xinyu Yang, Nieng Yan
Structural basis for different ω-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels. Cell research 34 (6) (2024)
Jian Huang, Xiaojing Pan, Nieng Yan
Structural biology and molecular pharmacology of voltage-gated ion channels. Nature reviews. Molecular cell biology (2024)
Zhangqiang Li, Qiurong Wu, Gaoxingyu Huang, Xueqin Jin, Jiaao Li, Xiaojing Pan, Nieng Yan
Dissection of the structure-function relationship of Na v channels. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Jian Huang, Xiao Fan, Xueqin Jin, Chen Lyu, Qinmeng Guo, Tao Liu, Jiaofeng Chen, Amaël Davakan, Philippe Lory, Nieng Yan
Structural basis for human Ca v 3.2 inhibition by selective antagonists. Cell research 34 (6) (2024)
Zhangqiang Li, Ye Cong, Tong Wu, Tongtong Wang, Xinyao Lou, Xinyu Yang, Nieng Yan
Structural basis for different ω-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels. Cell research 34 (6) (2024)
Zhangqiang Li, Qiurong Wu, Gaoxingyu Huang, Xueqin Jin, Jiaao Li, Xiaojing Pan, Nieng Yan
Dissection of the structure-function relationship of Na v channels. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Zhangqiang Li, Ye Cong, Tong Wu, Tongtong Wang, Xinyao Lou, Xinyu Yang, Nieng Yan
Structural basis for different ω-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels. Cell research 34 (6) (2024)
Zhangqiang Li, Qiurong Wu, Gaoxingyu Huang, Xueqin Jin, Jiaao Li, Xiaojing Pan, Nieng Yan
Dissection of the structure-function relationship of Na v channels. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Zhangqiang Li, Qiurong Wu, Gaoxingyu Huang, Xueqin Jin, Jiaao Li, Xiaojing Pan, Nieng Yan
Dissection of the structure-function relationship of Na v channels. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Zhangqiang Li, Qiurong Wu, Gaoxingyu Huang, Xueqin Jin, Jiaao Li, Xiaojing Pan, Nieng Yan
Dissection of the structure-function relationship of Na v channels. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Peng Huang, Raminta Venskutonytė, Rashmi B Prasad, Hamidreza Ardalani, Sofia W de Maré, Xiao Fan, Ping Li, Peter Spégel, Nieng Yan, Pontus Emanuel Gourdon, Isabella Artner, Karin Lindkvist-Petersson
Cryo-EM structure supports a role of AQP7 as a junction protein. Nature communications 14 (1) (2023)
Xiao Fan, Jian Huang, Xueqin Jin, Nieng Yan
Cryo-EM structure of human voltage-gated sodium channel Na v 1.6. Proceedings of the National Academy of Sciences of the United States of America 120 (5) (2023)
Xia Yao, Shuai Gao, Nieng Yan
Structural biology of voltage-gated calcium channels. Channels (Austin, Tex.) 18 (1) (2023)
Peng Huang, Raminta Venskutonytė, Rashmi B Prasad, Hamidreza Ardalani, Sofia W de Maré, Xiao Fan, Ping Li, Peter Spégel, Nieng Yan, Pontus Emanuel Gourdon, Isabella Artner, Karin Lindkvist-Petersson
Cryo-EM structure supports a role of AQP7 as a junction protein. Nature communications 14 (1) (2023)
Jian Huang, Xiao Fan, Xueqin Jin, Sooyeon Jo, Hanxiong Bear Zhang, Akie Fujita, Bruce P Bean, Nieng Yan
Cannabidiol inhibits Na v channels through two distinct binding sites. Nature communications 14 (1) (2023)
Peng Huang, Raminta Venskutonytė, Rashmi B Prasad, Hamidreza Ardalani, Sofia W de Maré, Xiao Fan, Ping Li, Peter Spégel, Nieng Yan, Pontus Emanuel Gourdon, Isabella Artner, Karin Lindkvist-Petersson
Cryo-EM structure supports a role of AQP7 as a junction protein. Nature communications 14 (1) (2023)
Peng Huang, Raminta Venskutonytė, Rashmi B Prasad, Hamidreza Ardalani, Sofia W de Maré, Xiao Fan, Ping Li, Peter Spégel, Nieng Yan, Pontus Emanuel Gourdon, Isabella Artner, Karin Lindkvist-Petersson
Cryo-EM structure supports a role of AQP7 as a junction protein. Nature communications 14 (1) (2023)
Zhangqiang Li, Qiurong Wu, Nieng Yan
A structural atlas of druggable sites on Na v channels. Channels (Austin, Tex.) 18 (1) (2023)
Xiao Fan, Jian Huang, Xueqin Jin, Nieng Yan
Cryo-EM structure of human voltage-gated sodium channel Na v 1.6. Proceedings of the National Academy of Sciences of the United States of America 120 (5) (2023)
Xiao Fan, Jian Huang, Xueqin Jin, Nieng Yan
Cryo-EM structure of human voltage-gated sodium channel Na v 1.6. Proceedings of the National Academy of Sciences of the United States of America 120 (5) (2023)
Jian Huang, Xiao Fan, Xueqin Jin, Liming Teng, Nieng Yan
Dual-pocket inhibition of Na v channels by the antiepileptic drug lamotrigine. Proceedings of the National Academy of Sciences of the United States of America 120 (41) (2023)
Peng Huang, Raminta Venskutonytė, Rashmi B Prasad, Hamidreza Ardalani, Sofia W de Maré, Xiao Fan, Ping Li, Peter Spégel, Nieng Yan, Pontus Emanuel Gourdon, Isabella Artner, Karin Lindkvist-Petersson
Cryo-EM structure supports a role of AQP7 as a junction protein. Nature communications 14 (1) (2023)
Xiao Fan, Jian Huang, Xueqin Jin, Nieng Yan
Cryo-EM structure of human voltage-gated sodium channel Na v 1.6. Proceedings of the National Academy of Sciences of the United States of America 120 (5) (2023)
Xiao Fan, Jian Huang, Xueqin Jin, Nieng Yan
Cryo-EM structure of human voltage-gated sodium channel Na v 1.6. Proceedings of the National Academy of Sciences of the United States of America 120 (5) (2023)
Qiurong Wu, Jian Huang, Xiao Fan, Kan Wang, Xueqin Jin, Gaoxingyu Huang, Jiaao Li, Xiaojing Pan, Nieng Yan
Structural mapping of Na v 1.7 antagonists. Nature communications 14 (1) (2023)
Xiao Fan, Jian Huang, Xueqin Jin, Nieng Yan
Cryo-EM structure of human voltage-gated sodium channel Na v 1.6. Proceedings of the National Academy of Sciences of the United States of America 120 (5) (2023)
Xia Yao, Shuai Gao, Nieng Yan
Structural basis for pore blockade of human voltage-gated calcium channel Ca v 1.3 by motion sickness drug cinnarizine. Cell research 32 (10) (2022)
Yafei Yuan, Fang Kong, Hanwen Xu, Angqi Zhu, Nieng Yan, Chuangye Yan
Cryo-EM structure of human glucose transporter GLUT4. Nature communications 13 (1) (2022)
Xin Jiang, Nieng Yan, Dong Deng, Chuangye Yan
Structural aspects of the glucose and monocarboxylate transporters involved in the Warburg effect. IUBMB life 74 (12) (2022)
Xiaoshuang Huang, Xueqin Jin, Gaoxingyu Huang, Jian Huang, Tong Wu, Zhangqiang Li, Jiaofeng Chen, Fang Kong, Xiaojing Pan, Nieng Yan
Structural basis for high-voltage activation and subtype-specific inhibition of human Na v 1.8. Proceedings of the National Academy of Sciences of the United States of America 119 (30) (2022)
Gaoxingyu Huang, Qiurong Wu, Zhangqiang Li, Xueqin Jin, Xiaoshuang Huang, Tong Wu, Xiaojing Pan, Nieng Yan
Unwinding and spiral sliding of S4 and domain rotation of VSD during the electromechanical coupling in Na v 1.7. Proceedings of the National Academy of Sciences of the United States of America 119 (33) (2022)
Xia Yao, Yan Wang, Zhifei Wang, Xiao Fan, Di Wu, Jian Huang, Alexander Mueller, Sarah Gao, Miaohui Hu, Carol V Robinson, Yong Yu, Shuai Gao, Nieng Yan
Structures of the R-type human Ca v 2.3 channel reveal conformational crosstalk of the intracellular segments. Nature communications 13 (1) (2022)
Nan Wang, Shuo Zhang, Yafei Yuan, Hanwen Xu, Elisabeth Defossa, Hans Matter, Melissa Besenius, Volker Derdau, Matthias K Dreyer, Nis Halland, Kaihui Hu He, Stefan Petry, Michael Podeschwa, Norbert Tennagels, Xin Jiang, Nieng Yan
Molecular basis for inhibiting human glucose transporters by exofacial inhibitors. Nature communications 13 (1) (2022)
Jian Huang, Yafei Yuan, Na Zhao, Debing Pu, Qingxuan Tang, Shuo Zhang, Shuchen Luo, Xikang Yang, Nan Wang, Yu Xiao, Tuan Zhang, Zhuoyi Liu, Tomoyo Sakata-Kato, Xin Jiang, Nobutaka Kato, Nieng Yan, Hang Yin
Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents. Proceedings of the National Academy of Sciences of the United States of America 118 (3) (2021)
Shuai Gao, Xia Yao, Nieng Yan
Structure of human Cav2.2 channel blocked by the painkiller ziconotide. Nature 596 (7870) (2021)
Zhangqiang Li, Xueqin Jin, Tong Wu, Xin Zhao, Weipeng Wang, Jianlin Lei, Xiaojing Pan, Nieng Yan
Structure of human Nav1.5 reveals the fast inactivation-related segments as a mutational hotspot for the long QT syndrome. Proceedings of the National Academy of Sciences of the United States of America 118 (11) (2021)
Xiaojing Pan, Zhangqiang Li, Xueqin Jin, Yanyu Zhao, Gaoxingyu Huang, Xiaoshuang Huang, Zilin Shen, Yong Cao, Meng-Qiu Dong, Jianlin Lei, Nieng Yan
Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies. Proceedings of the National Academy of Sciences of the United States of America 118 (11) (2021)
Renhong Yan, Pingping Cao, Wenqi Song, Hongwu Qian, Ximing Du, Hudson W Coates, Xin Zhao, Yaning Li, Shuai Gao, Xin Gong, Ximing Liu, Jianhua Sui, Jianlin Lei, Hongyuan Yang, Andrew J Brown, Qiang Zhou, Chuangye Yan, Nieng Yan
A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols. Science (New York, N.Y.) 371 (6533) (2021)
Zhangqiang Li, Xueqin Jin, Tong Wu, Gaoxingyu Huang, Kun Wu, Jianlin Lei, Xiaojing Pan, Nieng Yan
Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Nav 1.5 by the Antiarrhythmic Drug Quinidine*. Angewandte Chemie (International ed. in English) 60 (20) (2021)
Shuai Gao, Nieng Yan
Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Cav 1.1 by Dihydropyridine Compounds*. Angewandte Chemie (International ed. in English) 60 (6) (2020)
Hongwu Qian, Xin Zhao, Renhong Yan, Xia Yao, Shuai Gao, Xue Sun, Ximing Du, Hongyuan Yang, Catherine C L Wong, Nieng Yan
Structural basis for catalysis and substrate specificity of human ACAT1. Nature 581 (7808) (2020)
Shuai Gao, William C Valinsky, Nguyen Cam On, Patrick R Houlihan, Qian Qu, Lei Liu, Xiaojing Pan, David E Clapham, Nieng Yan
Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na+ channels in nanodisc. Proceedings of the National Academy of Sciences of the United States of America 117 (25) (2020)
Yaping Pan, Zhenning Ren, Shuai Gao, Jiemin Shen, Lie Wang, Zhichun Xu, Ye Yu, Preetham Bachina, Hanzhi Zhang, Xiao Fan, Arthur D Laganowsky, Nieng Yan, Ming Zhou
Structural basis of ion transport and inhibition in ferroportin. Nature communications 11 (1) (2020)
Lie Wang, Hongwu Qian, Ming-Hua Qiu, Yimo Han, Zhenning Ren, Hanzhi Zhang, Liya Hu, B V Venkataram Prasad, Arthur Laganowsky, Nieng Yan, Ming Zhou
Structure and mechanism of human diacylglycerol O-acyltransferase 1. Nature 581 (7808) (2020)
Xia Yao, Xiao Fan, Nieng Yan
Cryo-EM analysis of a membrane protein embedded in the liposome. Proceedings of the National Academy of Sciences of the United States of America 117 (31) (2020)
Huaizong Shen, Dongliang Liu, Kun Wu, Jianlin Lei, Nieng Yan
Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins. Science (New York, N.Y.) 363 (6433) (2019)
Xiaojing Pan, Zhangqiang Li, Xiaoshuang Huang, Gaoxingyu Huang, Shuai Gao, Huaizong Shen, Sanling Liu, Jianlin Lei, Nieng Yan
Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ-conotoxin KIIIA. Science (New York, N.Y.) 363 (6433) (2019)
Juanrong Zhang, Wenzhi Mao, Yanhui Ren, Rui-Ning Sun, Nieng Yan, Haipeng Gong
Simulating the ion permeation and ion selection for a eukaryotic voltage-gated sodium channel NaVPaS. Protein & cell 9 (6) (2019)
Huaizong Shen, Zhangqiang Li, Yan Jiang, Xiaojing Pan, Jianping Wu, Ben Cristofori-Armstrong, Jennifer J Smith, Yanni K-Y Chin, Jianlin Lei, Qiang Zhou, Glenn F King, Nieng Yan
Structural basis for the modulation of voltage-gated sodium channels by animal toxins. Science (New York, N.Y.) 362 (6412) (2018)
Xin Gong, Hongwu Qian, Pingping Cao, Xin Zhao, Qiang Zhou, Jianlin Lei, Nieng Yan
Structural basis for the recognition of Sonic Hedgehog by human Patched1. Science (New York, N.Y.) 361 (6402) (2018)
Xiaojing Pan, Zhangqiang Li, Qiang Zhou, Huaizong Shen, Kun Wu, Xiaoshuang Huang, Jiaofeng Chen, Juanrong Zhang, Xuechen Zhu, Jianlin Lei, Wei Xiong, Haipeng Gong, Bailong Xiao, Nieng Yan
Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1. Science (New York, N.Y.) 362 (6412) (2018)
Huaizong Shen, Qiang Zhou, Xiaojing Pan, Zhangqiang Li, Jianping Wu, Nieng Yan
Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution. Science (New York, N.Y.) 355 (6328) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Nieng Yan