Andrew J Brown (A J Brown)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 21

Top Topics

Low Density Lipoprotein

Endoplasmic Reticulum

Top Venues

BioEssays : news and reviews in molecular, cellular and developmental biology

Nature metabolism

The Journal of biological chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Nicole M Fenton, Lydia Qian, Eloise G Paine, Laura J Sharpe, Andrew J Brown
A paREDOX in the control of cholesterol biosynthesis: Does the NADPH sensor and E3 ubiquitin ligase MARCHF6 protect mammalian cells during oxidative stress by controlling sterol biosynthesis? BioEssays : news and reviews in molecular, cellular and developmental biology 46 (7) (2024)
Nicole M Fenton, Lydia Qian, Eloise G Paine, Laura J Sharpe, Andrew J Brown
A paREDOX in the control of cholesterol biosynthesis: Does the NADPH sensor and E3 ubiquitin ligase MARCHF6 protect mammalian cells during oxidative stress by controlling sterol biosynthesis? BioEssays : news and reviews in molecular, cellular and developmental biology 46 (7) (2024)
Nicole M Fenton, Lydia Qian, Eloise G Paine, Laura J Sharpe, Andrew J Brown
A paREDOX in the control of cholesterol biosynthesis: Does the NADPH sensor and E3 ubiquitin ligase MARCHF6 protect mammalian cells during oxidative stress by controlling sterol biosynthesis? BioEssays : news and reviews in molecular, cellular and developmental biology (2024)
Nicole M Fenton, Lydia Qian, Eloise G Paine, Laura J Sharpe, Andrew J Brown
A paREDOX in the control of cholesterol biosynthesis: Does the NADPH sensor and E3 ubiquitin ligase MARCHF6 protect mammalian cells during oxidative stress by controlling sterol biosynthesis? BioEssays : news and reviews in molecular, cellular and developmental biology 46 (7) (2024)
Hudson W Coates, Andrew J Brown
Asters: rising stars in the cholesterol universe. Nature metabolism (2023)
Hudson W Coates, Andrew J Brown
Asters: rising stars in the cholesterol universe. Nature metabolism 5 (1) (2023)
Hudson W Coates, Isabelle M Capell-Hattam, Ellen M Olzomer, Ximing Du, Rhonda Farrell, Hongyuan Yang, Frances L Byrne, Andrew J Brown
Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase. eLife 12 (2023)
Hudson W Coates, Isabelle M Capell-Hattam, Ellen M Olzomer, Ximing Du, Rhonda Farrell, Hongyuan Yang, Frances L Byrne, Andrew J Brown
Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase. eLife 12 (2023)
Hudson W Coates, Isabelle M Capell-Hattam, Ellen M Olzomer, Ximing Du, Rhonda Farrell, Hongyuan Yang, Frances L Byrne, Andrew J Brown
Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase. eLife 12 (2023)
Hudson W Coates, Andrew J Brown
Asters: rising stars in the cholesterol universe. Nature metabolism 5 (1) (2023)
Hudson W Coates, Andrew J Brown
Asters: rising stars in the cholesterol universe. Nature metabolism 5 (1) (2023)
Hudson W Coates, Isabelle M Capell-Hattam, Ellen M Olzomer, Ximing Du, Rhonda Farrell, Hongyuan Yang, Frances L Byrne, Andrew J Brown
Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase. eLife 12 (2023)
Hudson W Coates, Isabelle M Capell-Hattam, Ellen M Olzomer, Ximing Du, Rhonda Farrell, Hongyuan Yang, Frances L Byrne, Andrew J Brown
Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase. eLife 12 (2023)
Renhong Yan, Pingping Cao, Wenqi Song, Hongwu Qian, Ximing Du, Hudson W Coates, Xin Zhao, Yaning Li, Shuai Gao, Xin Gong, Ximing Liu, Jianhua Sui, Jianlin Lei, Hongyuan Yang, Andrew J Brown, Qiang Zhou, Chuangye Yan, Nieng Yan
A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols. Science (New York, N.Y.) 371 (6533) (2021)
P Simonen, S Li, N K Chua, A-M Lampi, V Piironen, J Lommi, J Sinisalo, Andrew J Brown, E Ikonen, Helena Gylling
Amiodarone disrupts cholesterol biosynthesis pathway and causes accumulation of circulating desmosterol by inhibiting 24-dehydrocholesterol reductase. Journal of internal medicine 288 (5) (2020)
Laura Sharpe, Hudson W Coates, Andrew J Brown
Post-translational control of the long and winding road to cholesterol. The Journal of biological chemistry (2020)
Ngee Kiat Chua, Andrew J Brown
Lipid sensing tips the balance for a key cholesterol synthesis enzyme. Journal of lipid research 61 (11) (2020)
Yanqing Xu, Ximing Du, Nigel Turner, Andrew J Brown, Hongyuan Yang
Enhanced acyl-CoA:cholesterol acyltransferase activity increases cholesterol levels on the lipid droplet surface and impairs adipocyte function. The Journal of biological chemistry 294 (50) (2019)
Ngee Kiat Chua, Hudson W Coates, Andrew J Brown
Cholesterol, cancer, and rebooting a treatment for athlete's foot. Science translational medicine 10 (437) (2019)
Hudson W Coates, Andrew J Brown
A wolf in sheep's clothing: unmasking the lanosterol-induced degradation of HMG-CoA reductase. Journal of lipid research 60 (10) (2019)
Ngee Kiat Chua, Nicola A Scott, Andrew J Brown
Valosin-containing protein mediates the ERAD of squalene monooxygenase and its cholesterol-responsive degron. The Biochemical journal 476 (18) (2019)