Sanling Liu (Lei Liu)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 55

Top Topics

Molecular Dynamics Simulations

Structural Basis

Single Molecule

Top Venues

Angewandte Chemie (International ed. in English)

Nature structural & molecular biology

Journal of the American Chemical Society

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Xiangwei Wu, Yunxiang Du, Lu-Jun Liang, Ruichao Ding, Tianyi Zhang, Hongyi Cai, Xiaolin Tian, Man Pan, Sanling Liu
Structure-guided engineering enables E3 ligase-free and versatile protein ubiquitination via UBE2E1. Nature communications 15 (1) (2024)
Zebin Tong, Hua-Song Ai, Ziyu Xu, Kezhang He, Guo-Chao Chu, Qiang Shi, Zhiheng Deng, Qiaomei Xue, Maoshen Sun, Yunxiang Du, Lujun Liang, Jia-Bin Li, Man Pan, Sanling Liu
Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes. Nature structural & molecular biology (2024)
Zebin Tong, Hua-Song Ai, Ziyu Xu, Kezhang He, Guo-Chao Chu, Qiang Shi, Zhiheng Deng, Qiaomei Xue, Maoshen Sun, Yunxiang Du, Lujun Liang, Jia-Bin Li, Man Pan, Sanling Liu
Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes. Nature structural & molecular biology (2024)
Zebin Tong, Hua-Song Ai, Ziyu Xu, Kezhang He, Guo-Chao Chu, Qiang Shi, Zhiheng Deng, Qiaomei Xue, Maoshen Sun, Yunxiang Du, Lujun Liang, Jia-Bin Li, Man Pan, Sanling Liu
Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes. Nature structural & molecular biology 31 (2) (2024)
Xiangwei Wu, Yunxiang Du, Lu-Jun Liang, Ruichao Ding, Tianyi Zhang, Hongyi Cai, Xiaolin Tian, Man Pan, Sanling Liu
Structure-guided engineering enables E3 ligase-free and versatile protein ubiquitination via UBE2E1. Nature communications 15 (1) (2024)
Hua-Song Ai, Zaozhen He, Zhiheng Deng, Guo-Chao Chu, Qiang Shi, Zebin Tong, Jia-Bin Li, Man Pan, Sanling Liu
Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16. Nature structural & molecular biology (2024)
Zebin Tong, Hua-Song Ai, Ziyu Xu, Kezhang He, Guo-Chao Chu, Qiang Shi, Zhiheng Deng, Qiaomei Xue, Maoshen Sun, Yunxiang Du, Lujun Liang, Jia-Bin Li, Man Pan, Sanling Liu
Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes. Nature structural & molecular biology 31 (2) (2024)
Xiangwei Wu, Yunxiang Du, Lu-Jun Liang, Ruichao Ding, Tianyi Zhang, Hongyi Cai, Xiaolin Tian, Man Pan, Sanling Liu
Structure-guided engineering enables E3 ligase-free and versatile protein ubiquitination via UBE2E1. Nature communications 15 (1) (2024)
Zebin Tong, Hua-Song Ai, Ziyu Xu, Kezhang He, Guo-Chao Chu, Qiang Shi, Zhiheng Deng, Qiaomei Xue, Maoshen Sun, Yunxiang Du, Lujun Liang, Jia-Bin Li, Man Pan, Sanling Liu
Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes. Nature structural & molecular biology 31 (2) (2024)
Zebin Tong, Hua-Song Ai, Ziyu Xu, Kezhang He, Guo-Chao Chu, Qiang Shi, Zhiheng Deng, Qiaomei Xue, Maoshen Sun, Yunxiang Du, Lujun Liang, Jia-Bin Li, Man Pan, Sanling Liu
Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes. Nature structural & molecular biology 31 (2) (2024)
Ke Sun, Sicong Li, Bowen Zheng, Yanlei Zhu, Tongyue Wang, Mingfu Liang, Yue Yao, Kairan Zhang, Jizhong Zhang, Hongyong Li, Dongyang Han, Ji-Shen Zheng, Brian Coventry, Longxing Cao, David Baker, Sanling Liu, Peilong Lu
Accurate de novo design of heterochiral protein-protein interactions. Cell research (2024)
Dong-Liang Huang, Wu-Chen Guo, Wei-Wei Shi, Yun-Pu Gao, Yong-Kang Zhou, Long-Jie Wang, Chen Wang, Shan Tang, Sanling Liu, Ji-Shen Zheng
Enhanced native chemical ligation by peptide conjugation in trifluoroacetic acid. Science advances 10 (29) (2024)
Hua-Song Ai, Man Pan, Sanling Liu
Chemical Synthesis of Human Proteoforms and Application in Biomedicine. ACS central science 10 (8) (2024)
Dong-Liang Huang, Wu-Chen Guo, Wei-Wei Shi, Yun-Pu Gao, Yong-Kang Zhou, Long-Jie Wang, Chen Wang, Shan Tang, Sanling Liu, Ji-Shen Zheng
Enhanced native chemical ligation by peptide conjugation in trifluoroacetic acid. Science advances 10 (29) (2024)
Hua-Song Ai, Man Pan, Sanling Liu
Chemical Synthesis of Human Proteoforms and Application in Biomedicine. ACS central science 10 (8) (2024)
Xiangwei Wu, Yunxiang Du, Lu-Jun Liang, Ruichao Ding, Tianyi Zhang, Hongyi Cai, Xiaolin Tian, Man Pan, Sanling Liu
Structure-guided engineering enables E3 ligase-free and versatile protein ubiquitination via UBE2E1. Nature communications 15 (1) (2024)
Rui Zhao, Pan Shi, Ji-Bin Cui, Chaowei Shi, Xiao-Xiong Wei, Jie Luo, Zhemin Xia, Wei-Wei Shi, Yingxin Zhou, Jiahui Tang, Changlin Tian, Mark Meininghaus, Donald Bierer, Jing Shi, Yi-Ming Li, Sanling Liu
Single-Shot Solid-Phase Synthesis of Full-Length H2 Relaxin Disulfide Surrogates. Angewandte Chemie (International ed. in English) 62 (6) (2023)
Rui Zhao, Pan Shi, Ji-Bin Cui, Chaowei Shi, Xiao-Xiong Wei, Jie Luo, Zhemin Xia, Wei-Wei Shi, Yingxin Zhou, Jiahui Tang, Changlin Tian, Mark Meininghaus, Donald Bierer, Jing Shi, Yi-Ming Li, Sanling Liu
Single-Shot Solid-Phase Synthesis of Full-Length H2 Relaxin Disulfide Surrogates. Angewandte Chemie (International ed. in English) 62 (6) (2023)
Huasong Ai, Sanling Liu
Paralog-specific recognition. Nature chemical biology (2023)
Baobao Chen, Chao Liu, Wei Cong, Fei Gao, Yan Zou, Li Su, Sanling Liu, Alexander Hillisch, Lutz Lehmann, Donald Bierer, Xiang Li, Hong-Gang Hu
Cyclobutane-bearing restricted anchoring residues enabled geometry-specific hydrocarbon peptide stapling. Chemical science 14 (41) (2023)
Lu-Jun Liang, Yu Wang, Xiao Hua, Rujing Yuan, Qiong Xia, Rongtian Wang, Chuntong Li, Guo-Chao Chu, Sanling Liu, Yi-Ming Li
Cell-Permeable Stimuli-Responsive Ubiquitin Probe for Time-Resolved Monitoring of Substrate Ubiquitination in Live Cells. JACS Au 3 (10) (2023)
Lingxiao Wang, Haodong Li, Yuefei Hu, Xichu Yang, Changlin Tian, Demeng Sun, Sanling Liu, Jinghong Li
Modification of Low-Energy Surfaces Using Bicyclic Peptides Discovered by Phage Display. Journal of the American Chemical Society (2023)
Rui Zhao, Pan Shi, Ji-Bin Cui, Chaowei Shi, Xiao-Xiong Wei, Jie Luo, Zhemin Xia, Wei-Wei Shi, Yingxin Zhou, Jiahui Tang, Changlin Tian, Mark Meininghaus, Donald Bierer, Jing Shi, Yi-Ming Li, Sanling Liu
Single-Shot Solid-Phase Synthesis of Full-Length H2 Relaxin Disulfide Surrogates. Angewandte Chemie (International ed. in English) 62 (6) (2023)
Tian Wang, Chuntong Li, Meijing Wang, Jiachen Zhang, Qingyun Zheng, Lujun Liang, Guochao Chu, Xiaolin Tian, Haiteng Deng, Wei He, Sanling Liu, Jinghong Li
Expedient Synthesis of Ubiquitin-like Protein ISG15 Tools through Chemo-Enzymatic Ligation Catalyzed by a Viral Protease Lb pro . Angewandte Chemie (International ed. in English) 61 (40) (2022)
Rui Zhao, Pan Shi, Ji-Bin Cui, Chaowei Shi, Xiao-Xiong Wei, Jie Luo, Zhemin Xia, Wei-Wei Shi, Yingxin Zhou, Jiahui Tang, Changlin Tian, Mark Meininghaus, Donald Bierer, Jing Shi, Yi-Ming Li, Sanling Liu
Single-Shot Solid-Phase Synthesis of Full-Length H2 Relaxin Disulfide Surrogates. Angewandte Chemie (International ed. in English) (2022)
Hua-Song Ai, Guo-Chao Chu, Qingyue Gong, Ze-Bin Tong, Zhiheng Deng, Xin Liu, Fan Yang, Ziyu Xu, Jia-Bin Li, Changlin Tian, Sanling Liu
Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes. Journal of the American Chemical Society 144 (40) (2022)
Chong Zuo, Ruichao Ding, Xiangwei Wu, Yuanxia Wang, Guo-Chao Chu, Lu-Jun Liang, Huasong Ai, Ze-Bin Tong, Junxiong Mao, Qingyun Zheng, Tian Wang, Zichen Li, Sanling Liu, Demeng Sun
Thioester-Assisted Sortase-A-Mediated Ligation. Angewandte Chemie (International ed. in English) 61 (28) (2022)
Hua-Song Ai, Maoshen Sun, Aijun Liu, Zixian Sun, Tingting Liu, Lin Cao, Lujun Liang, Qian Qu, Zichen Li, Zhiheng Deng, Zebin Tong, Guochao Chu, Xiaolin Tian, Haiteng Deng, Suwen Zhao, Jia-Bin Li, Zhiyong Lou, Sanling Liu
H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity. Nature chemical biology 18 (9) (2022)
Fan Yang, Huanhuan Zhang, Xianyu Meng, Yingge Li, Yingxin Zhou, Shenglong Ling, Demeng Sun, Pei Lv, Sanling Liu, Pan Shi, Changlin Tian
Structural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue. Cell research 32 (9) (2022)
Wei-Wei Shi, Chaowei Shi, Tong-Yue Wang, Yu-Lei Li, Yong-Kang Zhou, Xu-Han Zhang, Donald Bierer, Ji-Shen Zheng, Sanling Liu
Total Chemical Synthesis of Correctly Folded Disulfide-Rich Proteins Using a Removable O-Linked β- N -Acetylglucosamine Strategy. Journal of the American Chemical Society 144 (1) (2022)
Qing Bo, Fan Yang, Yingge Li, Xianyu Meng, Huanhuan Zhang, Yingxin Zhou, Shenglong Ling, Demeng Sun, Pei Lv, Sanling Liu, Pan Shi, Changlin Tian
Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues. Cell discovery 8 (1) (2022)
Lu-Jun Liang, Guo-Chao Chu, Qian Qu, Chong Zuo, Junxiong Mao, Qingyun Zheng, Jingnan Chen, Xianbin Meng, Yangwode Jing, Haiteng Deng, Yi-Ming Li, Sanling Liu
Chemical Synthesis of Activity-Based E2-Ubiquitin Probes for the Structural Analysis of E3 Ligase-Catalyzed Transthiolation. Angewandte Chemie (International ed. in English) 60 (31) (2021)
Yulei Li, Jie Heng, Demeng Sun, Baochang Zhang, Xin Zhang, Yupeng Zheng, Wei-Wei Shi, Tong-Yue Wang, Jiu-Yi Li, Xiaoou Sun, Xiangyu Liu, Ji-Shen Zheng, Brian K Kobilka, Sanling Liu
Chemical Synthesis of a Full-Length G-Protein-Coupled Receptor β2-Adrenergic Receptor with Defined Modification Patterns at the C-Terminus. Journal of the American Chemical Society 143 (42) (2021)
Shenglong Ling, Pan Shi, Sanling Liu, Xianyu Meng, Yingxin Zhou, Wenjing Sun, Shenghai Chang, Xing Zhang, Longhua Zhang, Chaowei Shi, Demeng Sun, Sanling Liu, Changlin Tian
Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan. Cell research 31 (4) (2021)
Man Pan, Qingyun Zheng, Tian Wang, Lujun Liang, Junxiong Mao, Chong Zuo, Ruichao Ding, Huasong Ai, Yuan Xie, Dong Si, Yuanyuan Yu, Sanling Liu, Minglei Zhao
Structural insights into Ubr1-mediated N-degron polyubiquitination. Nature 600 (7888) (2021)
Yuanyuan Yu, Qingyun Zheng, Satchal K Erramilli, Man Pan, Seongjin Park, Yuan Xie, Jingxian Li, Taekjip Ha, Anthony A Kossiakoff, Sanling Liu, Minglei Zhao
K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle. Nature chemical biology 17 (8) (2021)
Jinrui Zhang, Yao Sun, Qian Qu, Bo Li, Lili Zhang, Rui Gu, Jianlin Zuo, Wei Wei, Chao Ma, Sanling Liu, Kai Liu, Jingjing Li, Hong-Jie Zhang
Engineering non-covalently assembled protein nanoparticles for long-acting gouty arthritis therapy. Journal of materials chemistry. B (2021)
Man Pan, Yuanyuan Yu, Huasong Ai, Qingyun Zheng, Yuan Xie, Sanling Liu, Minglei Zhao
Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nature structural & molecular biology 28 (7) (2021)
Yue Zhao, Sanling Liu, Yingxin Zhou, Mengge Zhang, Haopeng Chen, H Eric Xu, Demeng Sun, Sanling Liu, Changlin Tian
Structural basis of human α7 nicotinic acetylcholine receptor activation. Cell research 31 (6) (2021)
Man Pan, Qingyun Zheng, Yuanyuan Yu, Huasong Ai, Yuan Xie, Xin Zeng, Chu Wang, Sanling Liu, Minglei Zhao
Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative. Nature communications 12 (1) (2021)
Jie Qing, Ming Wu, Rui Luo, Jizheng Chen, Lin Cao, Debin Zeng, Luqing Shang, Junxiu Nong, Qinkai Wu, Bi-Sen Ding, Xinwen Chen, Zihe Rao, Sanling Liu, Zhiyong Lou
Identification of Interferon Receptor IFNAR2 As a Novel HCV Entry Factor by Using Chemical Probes. ACS chemical biology 15 (5) (2020)
Yun-Kun Qi, Qian Qu, Donald Bierer, Sanling Liu
A Diaminodiacid (DADA) Strategy for the Development of Disulfide Surrogate Peptides. Chemistry, an Asian journal 15 (18) (2020)
Qian Qu, Shuai Gao, Fangming Wu, Meng-Ge Zhang, Ying Li, Long-Hua Zhang, Donald Bierer, Chang-Lin Tian, Ji-Shen Zheng, Sanling Liu
Synthesis of Disulfide Surrogate Peptides Incorporating Large-Span Surrogate Bridges Through a Native-Chemical-Ligation-Assisted Diaminodiacid Strategy. Angewandte Chemie (International ed. in English) 59 (15) (2020)
Xin Sui, Yu Wang, Yun-Xiang Du, Lu-Jun Liang, Qingyun Zheng, Yi-Ming Li, Sanling Liu
Development and application of ubiquitin-based chemical probes. Chemical science 11 (47) (2020)
Hongwei Liao, Xiang Li, Lianzheng Zhao, Yalong Wang, Xiaodan Wang, Ye Wu, Xin Zhou, Wei Fu, Sanling Liu, Hong-Gang Hu, Ye-Guang Chen
A PROTAC peptide induces durable β-catenin degradation and suppresses Wnt-dependent intestinal cancer. Cell discovery 6 (2020)
Rui Zhao, Pan Shi, Junyou Chen, Shuaishuai Sun, Jingnan Chen, Jibin Cui, Fangming Wu, Ge-Min Fang, Changlin Tian, Jing Shi, Donald Bierer, Sanling Liu, Yi-Ming Li
Chemical synthesis and biological activity of peptides incorporating an ether bridge as a surrogate for a disulfide bond. Chemical science 11 (30) (2020)
Dong-Liang Huang, Ying Li, Jun Liang, Lu Yu, Min Xue, Xiu-Xiu Cao, Bin Xiao, Chang-Lin Tian, Sanling Liu, Ji-Shen Zheng
The New Salicylaldehyde S,S-Propanedithioacetal Ester Enables N-to-C Sequential Native Chemical Ligation and Ser/Thr Ligation for Chemical Protein Synthesis. Journal of the American Chemical Society 142 (19) (2020)
Guo-Chao Chu, Man Pan, Jiabin Li, Sanling Liu, Chong Zuo, Ze-Bin Tong, Jing-Si Bai, Qingyue Gong, Huasong Ai, Jian Fan, Xianbin Meng, Yi-Chao Huang, Jing Shi, Haiteng Deng, Changlin Tian, Yi-Ming Li, Sanling Liu
Cysteine-Aminoethylation-Assisted Chemical Ubiquitination of Recombinant Histones. Journal of the American Chemical Society 141 (8) (2019)
Man Pan, Qingyun Zheng, Shan Ding, Lujia Zhang, Qian Qu, Tian Wang, Danning Hong, Yujing Ren, Lujun Liang, Chunlai Chen, Ziqing Mei, Sanling Liu
Chemical Protein Synthesis Enabled Mechanistic Studies on the Molecular Recognition of K27-linked Ubiquitin Chains. Angewandte Chemie (International ed. in English) 58 (9) (2019)
Baochang Zhang, Qiang Deng, Chong Zuo, Bingjia Yan, Chao Zuo, Xiu-Xiu Cao, Ting F Zhu, Ji-Shen Zheng, Sanling Liu
Ligation of Soluble but Unreactive Peptide Segments in the Chemical Synthesis of Haemophilus Influenzae DNA Ligase. Angewandte Chemie (International ed. in English) 58 (35) (2019)
Xiaojing Pan, Zhangqiang Li, Xiaoshuang Huang, Gaoxingyu Huang, Shuai Gao, Huaizong Shen, Sanling Liu, Jianlin Lei, Nieng Yan
Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ-conotoxin KIIIA. Science (New York, N.Y.) 363 (6433) (2019)
Huasong Ai, Yu Guo, Demeng Sun, Sanling Liu, Yunkun Qi, Jing Guo, Qian Qu, Qingyue Gong, Suwen Zhao, Jia-Bin Li, Lei Liu
Examination of the Deubiquitylation Site Selectivity of USP51 by Using Chemically Synthesized Ubiquitylated Histones. Chembiochem : a European journal of chemical biology 20 (2) (2018)
Tao Wang, Jian Fan, Xiao-Xu Chen, Rui Zhao, Yang Xu, Donald Bierer, Sanling Liu, Yi-Ming Li, Jing Shi, Ge-Min Fang
Synthesis of Peptide Disulfide-Bond Mimics by Using Fully Orthogonally Protected Diaminodiacids. Organic letters 20 (19) (2018)
Shan Tang, Lu-Jun Liang, Yan-Yan Si, Shuai Gao, Jia-Xing Wang, Jun Liang, Ziqing Mei, Ji-Shen Zheng, Sanling Liu
Practical Chemical Synthesis of Atypical Ubiquitin Chains by Using an Isopeptide-Linked Ub Isomer. Angewandte Chemie (International ed. in English) 56 (43) (2017)
Jia-Bin Li, Shan Tang, Ji-Shen Zheng, Chang-Lin Tian, Sanling Liu
Removable Backbone Modification Method for the Chemical Synthesis of Membrane Proteins. Accounts of chemical research 50 (5) (2017)