Jianlin Lei

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 41

Top Topics

Structural Basis

Electron Microscopy

Polycystic Kidney Disease

Top Venues

Science (New York, N.Y.)

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Jiaxin Tan, Yuan Xiao, Fang Kong, Xiao-Chun Zhang, Hanwen Xu, Angqi Zhu, Yiming Liu, Jianlin Lei, Bo-Xue Tian, Yafei Yuan, Chuangye Yan
Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature (2024)
Wenyu Zhang, Xiaofeng Zhang, Xiechao Zhan, Rui Bai, Jianlin Lei, Chuangye Yan, Yigong Shi
Structural insights into human exon-defined spliceosome prior to activation. Cell research (2024)
Jiaxin Tan, Yuan Xiao, Fang Kong, Xiao-Chun Zhang, Hanwen Xu, Angqi Zhu, Yiming Liu, Jianlin Lei, Bo-Xue Tian, Yafei Yuan, Chuangye Yan
Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature (2024)
Wenyu Zhang, Xiaofeng Zhang, Xiechao Zhan, Rui Bai, Jianlin Lei, Chuangye Yan, Yigong Shi
Structural insights into human exon-defined spliceosome prior to activation. Cell research 34 (6) (2024)
Jiaxin Tan, Yuan Xiao, Fang Kong, Xiao-Chun Zhang, Hanwen Xu, Angqi Zhu, Yiming Liu, Jianlin Lei, Bo-Xue Tian, Yafei Yuan, Chuangye Yan
Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature 632 (8026) (2024)
Xuefei Guo, Haotian Li, Chuangye Yan, Jianlin Lei, Rui Zhou, Yigong Shi
Molecular mechanism of substrate recognition and cleavage by human γ-secretase. Science (New York, N.Y.) 384 (6700) (2024)
Xuefei Guo, Haotian Li, Chuangye Yan, Jianlin Lei, Rui Zhou, Yigong Shi
Molecular mechanism of substrate recognition and cleavage by human γ-secretase. Science (New York, N.Y.) 384 (6700) (2024)
Wenyu Zhang, Xiaofeng Zhang, Xiechao Zhan, Rui Bai, Jianlin Lei, Chuangye Yan, Yigong Shi
Structural insights into human exon-defined spliceosome prior to activation. Cell research 34 (6) (2024)
Wenyu Zhang, Xiaofeng Zhang, Xiechao Zhan, Rui Bai, Jianlin Lei, Chuangye Yan, Yigong Shi
Structural insights into human exon-defined spliceosome prior to activation. Cell research 34 (6) (2024)
Jiaxin Tan, Yuan Xiao, Fang Kong, Xiao-Chun Zhang, Hanwen Xu, Angqi Zhu, Yiming Liu, Jianlin Lei, Bo-Xue Tian, Yafei Yuan, Chuangye Yan
Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature 632 (8026) (2024)
Angqi Zhu, Junhao Huang, Fang Kong, Jiaxin Tan, Jianlin Lei, Yafei Yuan, Chuangye Yan
Molecular basis for substrate recognition and transport of human GABA transporter GAT1. Nature structural & molecular biology (2023)
Haipeng Guan, Pei Wang, Pei Zhang, Chun Ruan, Yutian Ou, Bo Peng, Xiangdong Zheng, Jianlin Lei, Bing Li, Chuangye Yan, Haitao Li
Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature (2023)
Xuefei Guo, Yumeng Wang, Jiayao Zhou, Chen Jin, Jiaoni Wang, Bojun Jia, Dan Jing, Chuangye Yan, Jianlin Lei, Rui Zhou, Yigong Shi
Molecular basis for isoform-selective inhibition of presenilin-1 by MRK-560. Nature communications 13 (1) (2022)
Xuechen Zhu, Gaoxingyu Huang, Chao Zeng, Xiechao Zhan, Ke Liang, Qikui Xu, Yanyu Zhao, Pan Wang, Qifan Wang, Qiang Zhou, Qinghua Tao, Minhao Liu, Jianlin Lei, Chuangye Yan, Yigong Shi
Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex. Science (New York, N.Y.) 376 (6598) (2022)
Gaoxingyu Huang, Xiechao Zhan, Chao Zeng, Ke Liang, Xuechen Zhu, Yanyu Zhao, Pan Wang, Qifan Wang, Qiang Zhou, Qinghua Tao, Minhao Liu, Jianlin Lei, Chuangye Yan, Yigong Shi
Cryo-EM structure of the inner ring from the Xenopus laevis nuclear pore complex. Cell research 32 (5) (2022)
Yutian Jia, Yanming Zhang, Wenhao Wang, Jianlin Lei, Zhengxin Ying, Guanghui Yang
Structural and functional insights of the human peroxisomal ABC transporter ALDP. eLife 11 (2022)
Gaoxingyu Huang, Xiechao Zhan, Chao Zeng, Xuechen Zhu, Ke Liang, Yanyu Zhao, Pan Wang, Qifan Wang, Qiang Zhou, Qinghua Tao, Minhao Liu, Jianlin Lei, Chuangye Yan, Yigong Shi
Cryo-EM structure of the nuclear ring from Xenopus laevis nuclear pore complex. Cell research 32 (4) (2022)
Yaming Lu, Miao Yu, Yutian Jia, Fan Yang, Yanming Zhang, Xia Xu, Xiaomin Li, Fan Yang, Jianlin Lei, Yi Wang, Guanghui Yang
Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis. Nature communications 13 (1) (2022)
Rui Bai, Ruixue Wan, Lin Wang, Kui Xu, Qiangfeng Cliff Zhang, Jianlin Lei, Yigong Shi
Structure of the activated human minor spliceosome. Science (New York, N.Y.) 371 (6535) (2021)
Renhong Yan, Pingping Cao, Wenqi Song, Hongwu Qian, Ximing Du, Hudson W Coates, Xin Zhao, Yaning Li, Shuai Gao, Xin Gong, Ximing Liu, Jianhua Sui, Jianlin Lei, Hongyuan Yang, Andrew J Brown, Qiang Zhou, Chuangye Yan, Nieng Yan
A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols. Science (New York, N.Y.) 371 (6533) (2021)
Renhong Yan, Jiayao Zhou, Yaning Li, Jianlin Lei, Qiang Zhou
Structural insight into the substrate recognition and transport mechanism of the human LAT2-4F2hc complex. Cell discovery 6 (1) (2020)
Yanqing Zhang, Sai Li, Chao Zeng, Gaoxingyu Huang, Xuechen Zhu, Qifan Wang, Kunpeng Wang, Qiang Zhou, Chuangye Yan, Wusheng Zhang, Guangwen Yang, Minhao Liu, Qinghua Tao, Jianlin Lei, Yigong Shi
Molecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex. Cell research 30 (6) (2020)
Rui Bai, Ruixue Wan, Chuangye Yan, Qi Jia, Jianlin Lei, Yigong Shi
Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2. Science (New York, N.Y.) 371 (6525) (2020)
Gaoxingyu Huang, Yanqing Zhang, Xuechen Zhu, Chao Zeng, Qifan Wang, Qiang Zhou, Qinghua Tao, Minhao Liu, Jianlin Lei, Chuangye Yan, Yigong Shi
Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis. Cell research 30 (6) (2020)
Renhong Yan, Yaning Li, Yi Shi, Jiayao Zhou, Jianlin Lei, Jing Huang, Qiang Zhou
Cryo-EM structure of the human heteromeric amino acid transporter b0,+AT-rBAT. Science advances 6 (16) (2020)
Ximin Chi, Xueqin Jin, Yun Chen, Xiaoli Lu, Xinyu Tu, Xiaorong Li, Yuanyuan Zhang, Jianlin Lei, Jing Huang, Zhuo Huang, Qiang Zhou, Xiaojing Pan
Structural insights into the gating mechanism of human SLC26A9 mediated by its C-terminal sequence. Cell discovery 6 (2020)
Xiaofeng Zhang, Xiechao Zhan, Chuangye Yan, Wenyu Zhang, Dongliang Liu, Jianlin Lei, Yigong Shi
Structures of the human spliceosomes before and after release of the ligated exon. Cell research 29 (4) (2019)
Huaizong Shen, Dongliang Liu, Kun Wu, Jianlin Lei, Nieng Yan
Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins. Science (New York, N.Y.) 363 (6433) (2019)
Qi Liu, Bingting Ma, Nianchao Qian, Fan Zhang, Xu Tan, Jianlin Lei, Ye Xiang
Structure of the African swine fever virus major capsid protein p72. Cell research 29 (11) (2019)
Rui Zhou, Guanghui Yang, Xuefei Guo, Qiang Zhou, Jianlin Lei, Yigong Shi
Recognition of the amyloid precursor protein by human γ-secretase. Science (New York, N.Y.) 363 (6428) (2019)
Xiaojing Pan, Zhangqiang Li, Xiaoshuang Huang, Gaoxingyu Huang, Shuai Gao, Huaizong Shen, Sanling Liu, Jianlin Lei, Nieng Yan
Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ-conotoxin KIIIA. Science (New York, N.Y.) 363 (6433) (2019)
Xiao Fan, Jia Wang, Xing Zhang, Zi Yang, Jin-Can Zhang, Lingyun Zhao, Hai-Lin Peng, Jianlin Lei, Hong-Wei Wang
Single particle cryo-EM reconstruction of 52 kDa streptavidin at 3.2 Angstrom resolution. Nature communications 10 (1) (2019)
Gaochao Liu, Xiangdong Zheng, Haipeng Guan, Yong Cao, Hongyuan Qu, Junqing Kang, Xiangle Ren, Jianlin Lei, Meng-Qiu Dong, Xueming Li, Haitao Li
Architecture of Saccharomyces cerevisiae SAGA complex. Cell discovery 5 (2019)
Qiang Su, Feizhuo Hu, Xiaofei Ge, Jianlin Lei, Shengqiang Yu, Tingliang Wang, Qiang Zhou, Changlin Mei, Yigong Shi
Structure of the human PKD1-PKD2 complex. Science (New York, N.Y.) 361 (6406) (2018)
Qiang Su, Feizhuo Hu, Yuxia Liu, Xiaofei Ge, Changlin Mei, Shengqiang Yu, Aiwen Shen, Qiang Zhou, Chuangye Yan, Jianlin Lei, Yanqing Zhang, Xiaodong Liu, Tingliang Wang
Cryo-EM structure of the polycystic kidney disease-like channel PKD2L1. Nature communications 9 (1) (2018)
Huaizong Shen, Zhangqiang Li, Yan Jiang, Xiaojing Pan, Jianping Wu, Ben Cristofori-Armstrong, Jennifer J Smith, Yanni K-Y Chin, Jianlin Lei, Qiang Zhou, Glenn F King, Nieng Yan
Structural basis for the modulation of voltage-gated sodium channels by animal toxins. Science (New York, N.Y.) 362 (6412) (2018)
Xin Gong, Hongwu Qian, Pingping Cao, Xin Zhao, Qiang Zhou, Jianlin Lei, Nieng Yan
Structural basis for the recognition of Sonic Hedgehog by human Patched1. Science (New York, N.Y.) 361 (6402) (2018)
Deshun Gong, Ximin Chi, Kang Ren, Gaoxingyu Huang, Gewei Zhou, Nieng Yan, Jianlin Lei, Qiang Zhou
Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin. Nature communications 9 (1) (2018)
Rui Bai, Ruixue Wan, Chuangye Yan, Jianlin Lei, Yigong Shi
Structures of the fully assembled Saccharomyces cerevisiae spliceosome before activation. Science (New York, N.Y.) 360 (6396) (2018)
Xiechao Zhan, Chuangye Yan, Xiaofeng Zhang, Jianlin Lei, Yigong Shi
Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell research 28 (12) (2018)
Xiaojing Pan, Zhangqiang Li, Qiang Zhou, Huaizong Shen, Kun Wu, Xiaoshuang Huang, Jiaofeng Chen, Juanrong Zhang, Xuechen Zhu, Jianlin Lei, Wei Xiong, Haipeng Gong, Bailong Xiao, Nieng Yan
Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1. Science (New York, N.Y.) 362 (6412) (2018)