Oleksandr O Grygorenko

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 60

Top Venues

The Journal of organic chemistry

Chemistry (Weinheim an der Bergstrasse, Germany)

Chemical record (New York, N.Y.)

Future medicinal chemistry

Enamine Ltd

Taras Shevchenko National University of Kyiv (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Enamine Ltd

Ukraine

Consulting scientist

Taras Shevchenko National University of Kyiv

Ukraine

Associate Professor :: Department of Chemistry

Life Chemicals

Ukraine

Head of Medicinal and Computational Chemistry Department

Enamine Ltd

Ukraine

Principal Scientist

Taras Shevchenko National University of Kyiv

Ukraine

Assistant Professor :: Department of Chemistry

Education History

Taras Shevchenko National University of Kyiv

Ukraine

PHD :: Department of Chemistry

Publications

Oleksandr O Grygorenko, Rostislav D Lampeka, Valentyn A Chebanov, Maksym V Kovalenko, Stefan Wuttke
Chemistry in Ukraine. Chemical record (New York, N.Y.) (2024)
Evgeniy Y Slobodyanyuk, Ilona Tarasiuk, Taras Pasichnyk, Dmitriy M Volochnyuk, Dmytro O Sibgatulin, Oleksandr O Grygorenko
(Diazomethyl)dimethylphosphine Oxide - A Diazoalkane Reagent for [3+2] Cycloadditions. Chemistry (Weinheim an der Bergstrasse, Germany) (2024)
Evgen V Govor, Vasyl Naumchyk, Ihor Nestorak, Dmytro S Radchenko, Dmytro Dudenko, Yurii S Moroz, Olexiy D Kachkovsky, Oleksandr O Grygorenko
Generation of multimillion chemical space based on the parallel Groebke-Blackburn-Bienaymé reaction. Beilstein journal of organic chemistry 20 (2024)
Oleksandr O Grygorenko, Kostiantyn P Melnykov
Fluorinated building blocks in drug design: new pathways and targets. Future medicinal chemistry 16 (14) (2024)
Oleksandr O Grygorenko, Kostiantyn P Melnykov
Fluorinated building blocks in drug design: new pathways and targets. Future medicinal chemistry 16 (14) (2024)
Anton V Chernykh, Bohdan V Vashchenko, Svetlana V Shiskina, Dmitriy M Volochnyuk, Oleksandr O Grygorenko
3-Substituted 6-Azabicyclo[3.1.1]heptanes: Nonclassical Piperidine Isosteres for Drug Discovery. The Journal of organic chemistry 89 (15) (2024)
Volodymyr V Semeno, Vadym O Vasylchenko, Ihor M Fesun, Liudmyla Yu Ruzhylo, Mykhailo O Kipriianov, Kostiantyn P Melnykov, Artem Skreminskyi, Rustam Iminov, Pavel Mykhailiuk, Bohdan V Vashchenko, Oleksandr O Grygorenko
Bicyclo[m.n.k]alkane Building Blocks as Promising Benzene and Cycloalkane Isosteres: Multigram Synthesis, Physicochemical and Structural Characterization. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (12) (2024)
Serhii Holovach, Illia Poroshyn, Kostiantyn P Melnykov, Oleksandr S Liashuk, Olena O Pariiska, Sergey V Kolotilov, Alexander B Rozhenko, Dmitriy M Volochnyuk, Oleksandr O Grygorenko
Parallel Minisci Reaction of gem -Difluorocycloalkyl Building Blocks. ACS organic & inorganic Au 4 (4) (2024)
Oleksandr O Grygorenko, Kostiantyn P Melnykov
Fluorinated building blocks in drug design: new pathways and targets. Future medicinal chemistry 16 (14) (2024)
Vasyl Naumchyk, Vladyslav A Andriashvili, Dmytro S Radchenko, Dmytro Dudenko, Yurii S Moroz, Andrey A Tolmachev, Serhii Zhersh, Oleksandr O Grygorenko
S N Ar or Sulfonylation? Chemoselective Amination of Halo(het)arene Sulfonyl Halides for Synthetic Applications and Ultralarge Compound Library Design. The Journal of organic chemistry 89 (5) (2024)
Evgeniy Y Slobodyanyuk, Ilona Tarasiuk, Taras Pasichnyk, Dmitriy M Volochnyuk, Dmytro O Sibgatulin, Oleksandr O Grygorenko
(Diazomethyl)dimethylphosphine Oxide - A Diazoalkane Reagent for [3+2] Cycloadditions. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (23) (2024)
Vasyl Naumchyk, Vladyslav A Andriashvili, Dmytro S Radchenko, Dmytro Dudenko, Yurii S Moroz, Andrey A Tolmachev, Serhii Zhersh, Oleksandr O Grygorenko
S N Ar or Sulfonylation? Chemoselective Amination of Halo(het)arene Sulfonyl Halides for Synthetic Applications and Ultralarge Compound Library Design. The Journal of organic chemistry (2024)
Evgen V Govor, Vasyl Naumchyk, Ihor Nestorak, Dmytro S Radchenko, Dmytro Dudenko, Yurii S Moroz, Olexiy D Kachkovsky, Oleksandr O Grygorenko
Generation of multimillion chemical space based on the parallel Groebke-Blackburn-Bienaymé reaction. Beilstein journal of organic chemistry 20 (2024)
Oleksandr O Grygorenko, Kostiantyn P Melnykov
Fluorinated building blocks in drug design: new pathways and targets. Future medicinal chemistry (2024)
Oleksandr O Grygorenko, Kostiantyn P Melnykov
Fluorinated building blocks in drug design: new pathways and targets. Future medicinal chemistry 16 (14) (2024)
Axel Pahl, Oleksandr O Grygorenko, Ivan S Kondratov, Herbert Waldmann
Identification of readily available pseudo-natural products. RSC medicinal chemistry 15 (8) (2024)
Yevhen Krokhmaliuk, Ihor Kleban, Yuliya V Rassukana, Oleksandr O Grygorenko
Organocatalytic Decarboxylative Borylation of Cyclopropane N -Hydroxyphthalimide Esters. The Journal of organic chemistry 89 (4) (2024)
Serhii Holovach, Illia Poroshyn, Kostiantyn P Melnykov, Oleksandr S Liashuk, Olena O Pariiska, Sergey V Kolotilov, Alexander B Rozhenko, Dmitriy M Volochnyuk, Oleksandr O Grygorenko
Parallel Minisci Reaction of gem -Difluorocycloalkyl Building Blocks. ACS organic & inorganic Au 4 (4) (2024)
Anton V Chernykh, Bohdan V Vashchenko, Svetlana V Shiskina, Dmitriy M Volochnyuk, Oleksandr O Grygorenko
3-Substituted 6-Azabicyclo[3.1.1]heptanes: Nonclassical Piperidine Isosteres for Drug Discovery. The Journal of organic chemistry (2024)
Oleksandr O Grygorenko, Rostislav D Lampeka, Valentyn A Chebanov, Maksym V Kovalenko, Stefan Wuttke
Chemistry in Ukraine. Chemical record (New York, N.Y.) 24 (2) (2024)
Evgeniy Y Slobodyanyuk, Ilona Tarasiuk, Taras Pasichnyk, Dmitriy M Volochnyuk, Dmytro O Sibgatulin, Oleksandr O Grygorenko
(Diazomethyl)dimethylphosphine Oxide - A Diazoalkane Reagent for [3+2] Cycloadditions. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (23) (2024)
Yevhen Krokhmaliuk, Ihor Kleban, Yuliya V Rassukana, Oleksandr O Grygorenko
Organocatalytic Decarboxylative Borylation of Cyclopropane N -Hydroxyphthalimide Esters. The Journal of organic chemistry (2024)
Axel Pahl, Oleksandr O Grygorenko, Ivan S Kondratov, Herbert Waldmann
Identification of readily available pseudo-natural products. RSC medicinal chemistry 15 (8) (2024)
Serhii Holovach, Kostiantyn P Melnykov, Illia Poroshyn, Rustam T Iminov, Dmytro Dudenko, Ivan S Kondratov, Mark D Levin, Oleksandr O Grygorenko
C-C Coupling through Nitrogen Deletion: Application to Library Synthesis. Chemistry (Weinheim an der Bergstrasse, Germany) 29 (4) (2023)
Oleksandr S Liashuk, Vladyslav A Andriashvili, Andriy O Tolmachev, Oleksandr O Grygorenko
Chemoselective Reactions of Functionalized Sulfonyl Halides. Chemical record (New York, N.Y.) (2023)
Anton V Chernykh, Oleksandr V Kudryk, Oleksandr S Olifir, Alexey V Dobrydnev, Eduard Rusanov, Viktoriia S Moskvina, Dmitriy M Volochnyuk, Oleksandr O Grygorenko
Expanding the Chemical Space of 1,2-Difunctionalized Cyclobutanes. The Journal of organic chemistry (2023)
Bohdan Sosunovych, Bohdan V Vashchenko, Vladyslav A Andriashvili, Oleksandr O Grygorenko
Bypassing Sulfonyl Halides: Synthesis of Sulfonamides from Other Sulfur-Containing Building Blocks. Chemical record (New York, N.Y.) (2023)
Igor V Komarov, Volodymyr A Bugrov, Anton Cherednychenko, Oleksandr O Grygorenko
Insights into Modeling Approaches in Chemistry: Assessing Ligand-Protein Binding Thermodynamics Based on Rigid-Flexible Model Molecules. Chemical record (New York, N.Y.) (2023)
Serhii Holovach, Kostiantyn P Melnykov, Illia Poroshyn, Rustam T Iminov, Dmytro Dudenko, Ivan S Kondratov, Mark D Levin, Oleksandr O Grygorenko
C-C Coupling through Nitrogen Deletion: Application to Library Synthesis. Chemistry (Weinheim an der Bergstrasse, Germany) (2023)
Volodymyr V Semeno, Vadym O Vasylchenko, Ihor M Fesun, Liudmyla Yu Ruzhylo, Mykhailo O Kipriianov, Kostiantyn P Melnykov, Artem Skreminskyi, Rustam Iminov, Pavel Mykhailiuk, Bohdan V Vashchenko, Oleksandr O Grygorenko
Bicyclo[m.n.k]alkane Building Blocks as Promising Benzene and Cycloalkane Isosteres: Multigram Synthesis, Physicochemical and Structural Characterization. Chemistry (Weinheim an der Bergstrasse, Germany) (2023)
Anton V Chernykh, Oleksandr V Kudryk, Oleksandr S Olifir, Alexey V Dobrydnev, Eduard Rusanov, Viktoriia S Moskvina, Dmitriy M Volochnyuk, Oleksandr O Grygorenko
Expanding the Chemical Space of 1,2-Difunctionalized Cyclobutanes. The Journal of organic chemistry 88 (5) (2023)
Sergey Holovach, Kostiantyn P Melnykov, Artem Skreminskiy, Maksym Herasymchuk, Olha Tavlui, Danylo Aloshyn, Petro Borysko, Alexander B Rozhenko, Sergey V Ryabukhin, Dmitriy M Volochnyuk, Oleksandr O Grygorenko
Effect of gem-Difluorination on the Key Physicochemical Properties Relevant to Medicinal Chemistry: The Case of Functionalized Cycloalkanes. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (19) (2022)
Denys A Kvasha, Andrii Deviatkin, Andrii S Poturai, Pavel S Nosik, Andrii A Kyrylchuk, Sergiy Suikov, Alexander B Rozhenko, Dmitriy M Volochnyuk, Oleksandr O Grygorenko
Metal-Free C-H Difluoromethylation of Imidazoles with the Ruppert-Prakash Reagent. The Journal of organic chemistry (2022)
Anton V Chernykh, Danylo Aloshyn, Yuliya O Kuchkovska, Constantin Gabriel Daniliuc, Nataliya A Tolmachova, Ivan S Kondratov, Sergey Zozulya, Oleksandr O Grygorenko, Günter Haufe
Impact of β-perfluoroalkyl substitution of proline on the proteolytic stability of its peptide derivatives. Organic & biomolecular chemistry 20 (47) (2022)
Oleksandr O Grygorenko, Kostiantyn P Melnykov, Serhii Holovach, Oleksandr Demchuk
Fluorinated Cycloalkyl Building Blocks for Drug Discovery. ChemMedChem 17 (21) (2022)
Ivan S Kondratov, Yurii S Moroz, Christoph Gorgulla, Oleksandr O Grygorenko, Igor V Komarov, Gerhard Wagner, Andrey A Tolmachev
Challenges for chemistry in Ukraine after the war: Ukrainian science requires rebuilding and support. Proceedings of the National Academy of Sciences of the United States of America 119 (50) (2022)
Vladyslav A Andriashvili, Serhii Zhersh, Andrey A Tolmachev, Oleksandr O Grygorenko
Synthesis of α- C -Stereochemically Pure Secondary Sulfonamides. The Journal of organic chemistry 87 (9) (2022)
Oleksandr S Liashuk, Ihor A Ryzhov, Oleksandr V Hryshchuk, Bohdan V Vashchenko, Pavlo V Melnychuk, Yulian M Volovenko, Oleksandr O Grygorenko
Synthesis of 3-Borylated Pyrrolidines by 1,3-Dipolar Cycloaddition of Alkenyl Boronates and Azomethine Ylide. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (54) (2022)
Kostiantyn P Melnykov, Olha Tavlui, Artem Skreminskiy, Yuliya O Kuchkovska, Oleksandr O Grygorenko
Impact of Fluoroalkyl Substituents on the Physicochemical Properties of Saturated Heterocyclic Amines. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (55) (2022)
Ivan S Kondratov, Yurii S Moroz, Oleksandr O Grygorenko, Andrey A Tolmachev
The Ukrainian Factor in Early-Stage Drug Discovery in the Context of Russian Invasion: The Case of Enamine Ltd. ACS medicinal chemistry letters 13 (7) (2022)
Denys A Kvasha, Andrii Deviatkin, Andrii S Poturai, Pavel S Nosik, Andrii A Kyrylchuk, Sergiy Suikov, Alexander B Rozhenko, Dmitriy M Volochnyuk, Oleksandr O Grygorenko
Metal-Free C-H Difluoromethylation of Imidazoles with the Ruppert-Prakash Reagent. The Journal of organic chemistry 88 (1) (2022)
Dmytro S Radchenko, Vasyl S Naumchyk, Igor Dziuba, Andrii A Kyrylchuk, Kateryna E Gubina, Yurii S Moroz, Oleksandr O Grygorenko
One-pot parallel synthesis of 1,3,5-trisubstituted 1,2,4-triazoles. Molecular diversity (2021)
Dmitriy M Volochnyuk, Alina O Gorlova, Oleksandr O Grygorenko
Saturated Boronic Acids, Boronates, and Trifluoroborates: An Update on Their Synthetic and Medicinal Chemistry. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (62) (2021)
Bohdan A Chalyk, Andrii V Khutorianskyi, Bohdan V Vashchenko, Kyrylo Danyleiko, Anastasiia Grynyova, Anastasiia O Osipova, Andriy Kozytskiy, Darya Syniuchenko, Anton Tsymbaliuk, Konstantin S Gavrilenko, Angelina V Biitseva, Dmitriy M Volochnyuk, Igor V Komarov, Oleksandr O Grygorenko
Reductive Recyclization of sp3-Enriched Functionalized Isoxazolines into α-Hydroxy Lactams. The Journal of organic chemistry (2021)
Alla I Vaskevych, Nataliia O Savinchuk, Ruslan I Vaskevych, Eduard B Rusanov, Oleksandr O Grygorenko, Mykhailo V Vovk
The PIFA-initiated oxidative cyclization of 2-(3-butenyl)quinazolin-4(3 H )-ones - an efficient approach to 1-(hydroxymethyl)-2,3-dihydropyrrolo[1,2- a ]quinazolin-5(1 H )-ones. Beilstein journal of organic chemistry 17 (2021)
Oleksandr P Demchuk, Oleksandr V Hryshchuk, Bohdan V Vashchenko, Andriy V Kozytskiy, Andriy V Tymtsunik, Igor V Komarov, Oleksandr O Grygorenko
Photochemical [2 + 2] Cycloaddition of Alkenyl Boronic Derivatives: An Entry into 3-Azabicyclo[3.2.0]heptane Scaffold. The Journal of organic chemistry 85 (9) (2020)
Oleksandr P Blahun, Alexander B Rozhenko, Eduard Rusanov, Serhii Zhersh, Andrey A Tolmachev, Dmitriy M Volochnyuk, Oleksandr O Grygorenko
Twisting and Turning the Sulfonamide Bond: A Synthetic, Quantum Chemical, and Crystallographic Study. The Journal of organic chemistry 85 (8) (2020)
Volodymyr V Semeno, Vadym O Vasylchenko, Bohdan V Vashchenko, Dmytro O Lutsenko, Rustam T Iminov, Olesia B Volovenko, Oleksandr O Grygorenko
Building the Housane: Diastereoselective Synthesis and Characterization of Bicyclo[2.1.0]pentane Carboxylic Acids. The Journal of organic chemistry 85 (4) (2020)
Anton V Chernykh, Oleksandr S Olifir, Yuliya O Kuchkovska, Dmitriy M Volochnyuk, Vladimir S Yarmolchuk, Oleksandr O Grygorenko
Fluoroalkyl-Substituted Cyclopropane Derivatives: Synthesis and Physicochemical Properties. The Journal of organic chemistry 85 (19) (2020)
Yevhen M Ivon, Ivan V Mazurenko, Yuliya O Kuchkovska, Zoya V Voitenko, Oleksandr O Grygorenko
Formyl MIDA Boronate: C1 Building Block Enables Straightforward Access to α-Functionalized Organoboron Derivatives. Angewandte Chemie (International ed. in English) 59 (41) (2020)
Bohdan A Chalyk, Andrii Khutorianskyi, Andrii Lysenko, Yulia Fil, Yuliya O Kuchkovska, Konstantin S Gavrilenko, Iulia Bakanovych, Yurii S Moroz, Alina O Gorlova, Oleksandr O Grygorenko
Regioselective Synthesis of Functionalized 3- or 5-Fluoroalkyl Isoxazoles and Pyrazoles from Fluoroalkyl Ynones and Binucleophiles. The Journal of organic chemistry 84 (23) (2019)
Anton V Chernykh, Kostiantyn P Melnykov, Nataliya A Tolmacheva, Ivan S Kondratov, Dmytro S Radchenko, Constantin G Daniliuc, Dmitriy M Volochnyuk, Sergey V Ryabukhin, Yuliya O Kuchkovska, Oleksandr O Grygorenko
Last of the gem-Difluorocycloalkanes: Synthesis and Characterization of 2,2-Difluorocyclobutyl-Substituted Building Blocks. The Journal of organic chemistry 84 (13) (2019)
Olena Savych, Yuliya O Kuchkovska, Andrey V Bogolyubsky, Anzhelika I Konovets, Kateryna E Gubina, Sergey E Pipko, Anton V Zhemera, Alexander V Grishchenko, Dmytro N Khomenko, Volodymyr S Brovarets, Roman Doroschuk, Yurii S Moroz, Oleksandr O Grygorenko
One-Pot Parallel Synthesis of 5-(Dialkylamino)tetrazoles. ACS combinatorial science 21 (9) (2019)
Illia O Feskov, Anton V Chernykh, Yuliya O Kuchkovska, Constantin G Daniliuc, Ivan S Kondratov, Oleksandr O Grygorenko
3-((Hetera)cyclobutyl)azetidines, "Stretched" Analogues of Piperidine, Piperazine, and Morpholine: Advanced Building Blocks for Drug Discovery. The Journal of organic chemistry 84 (3) (2019)
Oleksandr O Grygorenko, Dmitriy M Volochnyuk, Sergey V Ryabukhin, Duncan B Judd
The Symbiotic Relationship Between Drug Discovery and Organic Chemistry. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (6) (2019)
Yevhenii M Sokolenko, Yevhen Yu Yurov, Bohdan V Vashchenko, Oleksandr V Hryshchuk, Yuliia Filimonova, Eugeniy N Ostapchuk, Artem Artemenko, Oleg V Zaremba, Oleksandr O Grygorenko
Far Away from Flatland. Synthesis and Molecular Structure of Dihetera[3.3.n]propellanes and Trihetera[3.3.n]propellanes: Advanced Analogues of Morpholine/Piperazine. The Journal of organic chemistry 84 (21) (2019)
Bohdan A Chalyk, Kateryna V Hrebeniuk, Yulia V Fil, Konstantin S Gavrilenko, Alexander B Rozhenko, Bohdan V Vashchenko, Oleksandr V Borysov, Angelina V Biitseva, Pavlo S Lebed, Iulia Bakanovych, Yurii S Moroz, Oleksandr O Grygorenko
Synthesis of 5-(Fluoroalkyl)isoxazole Building Blocks by Regioselective Reactions of Functionalized Halogenoximes. The Journal of organic chemistry 84 (24) (2019)
Sergiy V Zasukha, Vadim M Timoshenko, Andrey A Tolmachev, Valentyna O Pivnytska, Oleksii Gavrylenko, Serhii Zhersh, Yuriy Shermolovich, Oleksandr O Grygorenko
Sulfonimidamides and Imidosulfuric Diamides: Compounds from an Underexplored Part of Biologically Relevant Chemical Space. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (28) (2019)
Kateryna A Tolmachova, Yurii S Moroz, Angelika Konovets, Maxim O Platonov, Oleksandr V Vasylchenko, Petro Borysko, Sergey Zozulya, Anastasia Gryniukova, Andrey V Bogolubsky, Sergey Pipko, Pavel K Mykhailiuk, Volodymyr S Brovarets, Oleksandr O Grygorenko
(Chlorosulfonyl)benzenesulfonyl Fluorides-Versatile Building Blocks for Combinatorial Chemistry: Design, Synthesis and Evaluation of a Covalent Inhibitor Library. ACS combinatorial science 20 (11) (2018)
Andrey V Bogolubsky, Yurii S Moroz, Olena Savych, Sergey Pipko, Angelika Konovets, Maxim O Platonov, Oleksandr V Vasylchenko, Vasyl V Hurmach, Oleksandr O Grygorenko
An Old Story in the Parallel Synthesis World: An Approach to Hydantoin Libraries. ACS combinatorial science 20 (1) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Oleksandr O Grygorenko