Khaled M Darwish (Osama I El-Sabbagh)

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 44

Top Venues

Pharmaceuticals (Basel, Switzerland)

Metabolites

Microorganisms

Biology

Suez Canal University Faculty of Pharmacy

Suez Canal University Faculty of Pharmacy (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Suez Canal University Faculty of Pharmacy Mar 14 2016

Egypt

Assistant Professor :: Medicinal Chemistry

Suez Canal University Faculty of Pharmacy Jan 01 2013 - Mar 14 2016

Egypt

Assistant lecturer :: Medicinal Chemistry

Suez Canal University Faculty of Pharmacy Sep 01 2005 - Jan 01 2013

Egypt

Teacher Assistant (Demonstrator) :: Pharmaceutical Chemistry

Education History

Suez Canal University Faculty of Pharmacy Jan 01 2013 - Mar 14 2016

Egypt

PHD :: Medicinal Chemistry

Suez Canal University Faculty of Pharmacy Jan 01 2008 - Jan 01 2013

Egypt

MSC :: Medicinal Chemistry

Suez Canal University Faculty of Pharmacy Sep 01 2000 - Sep 01 2005

Egypt

BSC :: Pharmaceutical Sciences

Publications

Noha Fathallah, Wafaa M Elkady, Sara A Zahran, Khaled M Darwish, Sameh S Elhady, Yasmin A Elkhawas
Unveiling the Multifaceted Capabilities of Endophytic Aspergillus flavus Isolated from Annona squamosa Fruit Peels against Staphylococcus Isolates and HCoV 229E-In Vitro and In Silico Investigations. Pharmaceuticals (Basel, Switzerland) 17 (5) (2024)
Heba Aref, Sherin Hammad, Khaled M Darwish, Mohamed Saleh Elgawish
Unveiling Pharmacokinetics and Drug Interaction of Linagliptin and Pioglitazone HCl in Rat Plasma Using LC-MS/MS. Chemical research in toxicology 37 (5) (2024)
Noha Fathallah, Wafaa M Elkady, Sara A Zahran, Khaled M Darwish, Sameh S Elhady, Yasmin A Elkhawas
Unveiling the Multifaceted Capabilities of Endophytic Aspergillus flavus Isolated from Annona squamosa Fruit Peels against Staphylococcus Isolates and HCoV 229E-In Vitro and In Silico Investigations. Pharmaceuticals (Basel, Switzerland) 17 (5) (2024)
Fawzia F Albelwi, Mohamed S Nafie, Nader R Albujuq, Wafa Hourani, Ateyatallah Aljuhani, Khaled M Darwish, Mohamed M Tawfik, Nadjet Rezki, Mohamed Reda Aouad
Design and synthesis of chromene-1,2,3-triazole benzene sulfonamide hybrids as potent carbonic anhydrase-IX inhibitors against prostate cancer. RSC medicinal chemistry 15 (7) (2024)
Marwa Elsbaey, Yasuhiro Igarashi, Radwan Alnajjar, Khaled M Darwish, Tomofumi Miyamoto
Nuciferol C, a new sesquineolignan dimer from Cocos nucifera L.: bioactivity and theoretical investigation. RSC advances 14 (36) (2024)
Ahmed M Badawy, Marwa Samir M Donia, Nehal G Hamdy, Mayada M El-Ayouty, Osama G Mohamed, Khaled M Darwish, Ashootosh Tripathi, Safwat A Ahmed
Dual SARS-CoV-2 and MERS-CoV inhibitors from Artemisia monosperma : isolation, structure elucidation, molecular modelling studies, and in vitro activities. Organic & biomolecular chemistry 22 (34) (2024)
Ahmed M Badawy, Marwa Samir M Donia, Nehal G Hamdy, Mayada M El-Ayouty, Osama G Mohamed, Khaled M Darwish, Ashootosh Tripathi, Safwat A Ahmed
Dual SARS-CoV-2 and MERS-CoV inhibitors from Artemisia monosperma : isolation, structure elucidation, molecular modelling studies, and in vitro activities. Organic & biomolecular chemistry (2024)
Heba Aref, Sherin Hammad, Khaled M Darwish, Mohamed Saleh Elgawish
Unveiling Pharmacokinetics and Drug Interaction of Linagliptin and Pioglitazone HCl in Rat Plasma Using LC-MS/MS. Chemical research in toxicology (2024)
Mayada M El-Ayouty, Nermeen A Eltahawy, Ahmed M Abd El-Sameaa, Ahmed M Badawy, Khaled M Darwish, Sameh S Elhady, Mostafa M Shokr, Safwat A Ahmed
In vivo determination of analgesic and anti-inflammatory activities of isolated compounds from Cleome amblyocarpa and molecular modelling for the top active investigated compounds. RSC advances 14 (34) (2024)
Marwa Elsbaey, Yasuhiro Igarashi, Radwan Alnajjar, Khaled M Darwish, Tomofumi Miyamoto
Nuciferol C, a new sesquineolignan dimer from Cocos nucifera L.: bioactivity and theoretical investigation. RSC advances 14 (36) (2024)
Fawzia F Albelwi, Mohamed S Nafie, Nader R Albujuq, Wafa Hourani, Ateyatallah Aljuhani, Khaled M Darwish, Mohamed M Tawfik, Nadjet Rezki, Mohamed Reda Aouad
Design and synthesis of chromene-1,2,3-triazole benzene sulfonamide hybrids as potent carbonic anhydrase-IX inhibitors against prostate cancer. RSC medicinal chemistry 15 (7) (2024)
Mayada M El-Ayouty, Nermeen A Eltahawy, Ahmed M Abd El-Sameaa, Ahmed M Badawy, Khaled M Darwish, Sameh S Elhady, Mostafa M Shokr, Safwat A Ahmed
In vivo determination of analgesic and anti-inflammatory activities of isolated compounds from Cleome amblyocarpa and molecular modelling for the top active investigated compounds. RSC advances 14 (34) (2024)
Ahmed M Badawy, Marwa Samir M Donia, Nehal G Hamdy, Mayada M El-Ayouty, Osama G Mohamed, Khaled M Darwish, Ashootosh Tripathi, Safwat A Ahmed
Dual SARS-CoV-2 and MERS-CoV inhibitors from Artemisia monosperma : isolation, structure elucidation, molecular modelling studies, and in vitro activities. Organic & biomolecular chemistry 22 (34) (2024)
Hadil Faris Alotaibi, Haifa Alotaibi, Khaled M Darwish, El-Sayed Khafagy, Amr Selim Abu Lila, Mohamed A M Ali, Wael A H Hegazy, Samar Zuhair Alshawwa
The Anti-Virulence Activities of the Antihypertensive Drug Propranolol in Light of Its Anti-Quorum Sensing Effects against Pseudomonas aeruginosa and Serratia marcescens . Biomedicines 11 (12) (2023)
Rofida Albash, Noha M Badawi, Mohammed I A Hamed, Maha H Ragaie, Sahar S Mohammed, Rovan M Elbesh, Khaled M Darwish, Manar O Lashkar, Sameh S Elhady, Shaimaa Mosallam
Exploring the Synergistic Effect of Bergamot Essential Oil with Spironolactone Loaded Nano-Phytosomes for Treatment of Acne Vulgaris: In Vitro Optimization, In Silico Studies, and Clinical Evaluation. Pharmaceuticals (Basel, Switzerland) 16 (1) (2023)
Mohamed A Soltan, Muhammad Alaa Eldeen, Bayan H Sajer, Reda F A Abdelhameed, Fawziah A Al-Salmi, Eman Fayad, Ibrahim Jafri, Hebatallah Emam Mohammed Ahmed, Refaat A Eid, Hesham M Hassan, Mubarak Al-Shraim, Amr Negm, Ahmed Elsayed Noreldin, Khaled M Darwish
Integration of Chemoinformatics and Multi-Omics Analysis Defines ECT2 as a Potential Target for Cancer Drug Therapy. Biology 12 (4) (2023)
Sameh S Elhady, Noha M Alshobaki, Mahmoud A Elfaky, Abdulrahman E Koshak, Majed Alharbi, Reda F A Abdelhameed, Khaled M Darwish
Deciphering Molecular Aspects of Potential α -Glucosidase Inhibitors within Aspergillus terreus : A Computational Odyssey of Molecular Docking-Coupled Dynamics Simulations and Pharmacokinetic Profiling. Metabolites 13 (8) (2023)
Rofida Albash, Noha M Badawi, Mohammed I A Hamed, Maha H Ragaie, Sahar S Mohammed, Rovan M Elbesh, Khaled M Darwish, Manar O Lashkar, Sameh S Elhady, Shaimaa Mosallam
Exploring the Synergistic Effect of Bergamot Essential Oil with Spironolactone Loaded Nano-Phytosomes for Treatment of Acne Vulgaris: In Vitro Optimization, In Silico Studies, and Clinical Evaluation. Pharmaceuticals (Basel, Switzerland) 16 (1) (2023)
Hadil Faris Alotaibi, Haifa Alotaibi, Khaled M Darwish, El-Sayed Khafagy, Amr Selim Abu Lila, Mohamed A M Ali, Wael A H Hegazy, Samar Zuhair Alshawwa
The Anti-Virulence Activities of the Antihypertensive Drug Propranolol in Light of Its Anti-Quorum Sensing Effects against Pseudomonas aeruginosa and Serratia marcescens . Biomedicines 11 (12) (2023)
Hanin A Bogari, Sameh S Elhady, Khaled M Darwish, Mohamed S Refaey, Radi A Mohamed, Reda F A Abdelhameed, Ahmad J Almalki, Mohammed M Aldurdunji, Manar O Lashkar, Samah O Alshehri, Rania T Malatani, Koji Yamada, Amgad I M Khedr
Molecular and Biological Investigation of Isolated Marine Fungal Metabolites as Anticancer Agents: A Multi-Target Approach. Metabolites 13 (2) (2023)
Hanin A Bogari, Sameh S Elhady, Khaled M Darwish, Mohamed S Refaey, Radi A Mohamed, Reda F A Abdelhameed, Ahmad J Almalki, Mohammed M Aldurdunji, Manar O Lashkar, Samah O Alshehri, Rania T Malatani, Koji Yamada, Amgad I M Khedr
Molecular and Biological Investigation of Isolated Marine Fungal Metabolites as Anticancer Agents: A Multi-Target Approach. Metabolites 13 (2) (2023)
Mohamed A Soltan, Muhammad Alaa Eldeen, Bayan H Sajer, Reda F A Abdelhameed, Fawziah A Al-Salmi, Eman Fayad, Ibrahim Jafri, Hebatallah Emam Mohammed Ahmed, Refaat A Eid, Hesham M Hassan, Mubarak Al-Shraim, Amr Negm, Ahmed Elsayed Noreldin, Khaled M Darwish
Integration of Chemoinformatics and Multi-Omics Analysis Defines ECT2 as a Potential Target for Cancer Drug Therapy. Biology 12 (4) (2023)
Mohammed Y Behairy, Refaat A Eid, Hassan M Otifi, Heitham M Mohammed, Mohammed A Alshehri, Ashwag Asiri, Majed Aldehri, Mohamed Samir Ahmed Zaki, Khaled M Darwish, Sameh S Elhady, Nahla H El-Shaer, Muhammad Alaa Eldeen
Unraveling Extremely Damaging IRAK4 Variants and Their Potential Implications for IRAK4 Inhibitor Efficacy. Journal of personalized medicine 13 (12) (2023)
Hanin A Bogari, Sameh S Elhady, Khaled M Darwish, Mohamed S Refaey, Radi A Mohamed, Reda F A Abdelhameed, Ahmad J Almalki, Mohammed M Aldurdunji, Manar O Lashkar, Samah O Alshehri, Rania T Malatani, Koji Yamada, Amgad I M Khedr
Molecular and Biological Investigation of Isolated Marine Fungal Metabolites as Anticancer Agents: A Multi-Target Approach. Metabolites 13 (2) (2023)
Hanin A Bogari, Sameh S Elhady, Khaled M Darwish, Mohamed S Refaey, Radi A Mohamed, Reda F A Abdelhameed, Ahmad J Almalki, Mohammed M Aldurdunji, Manar O Lashkar, Samah O Alshehri, Rania T Malatani, Koji Yamada, Amgad I M Khedr
Molecular and Biological Investigation of Isolated Marine Fungal Metabolites as Anticancer Agents: A Multi-Target Approach. Metabolites 13 (2) (2023)
Rofida Albash, Noha M Badawi, Mohammed I A Hamed, Maha H Ragaie, Sahar S Mohammed, Rovan M Elbesh, Khaled M Darwish, Manar O Lashkar, Sameh S Elhady, Shaimaa Mosallam
Exploring the Synergistic Effect of Bergamot Essential Oil with Spironolactone Loaded Nano-Phytosomes for Treatment of Acne Vulgaris: In Vitro Optimization, In Silico Studies, and Clinical Evaluation. Pharmaceuticals (Basel, Switzerland) 16 (1) (2023)
Mohammed Y Behairy, Refaat A Eid, Hassan M Otifi, Heitham M Mohammed, Mohammed A Alshehri, Ashwag Asiri, Majed Aldehri, Mohamed Samir Ahmed Zaki, Khaled M Darwish, Sameh S Elhady, Nahla H El-Shaer, Muhammad Alaa Eldeen
Unraveling Extremely Damaging IRAK4 Variants and Their Potential Implications for IRAK4 Inhibitor Efficacy. Journal of personalized medicine 13 (12) (2023)
Hossam Mohamed Abdallah, Albraa T Kashegari, Akram A Shalabi, Khaled M Darwish, Ali M El Halawany, Mardi M Algandaby, Sabrin Ragab Mohamed Ibrahim, Gamal Abdallah Mohamed, Ashraf B Abdel-Naim, Abdulrahman E Koshak, Peter Proksch, Sameh S Elhady
Phenolics from Chrozophora oblongifolia Aerial Parts as Inhibitors of α-Glucosidases and Advanced Glycation End Products: In-Vitro Assessment, Molecular Docking and Dynamics Studies. Biology 11 (5) (2022)
Ahmad J Almalki, Tarek S Ibrahim, Sameh S Elhady, Khaled M Darwish, Wael A H Hegazy
Repurposing α -Adrenoreceptor Blockers as Promising Anti-Virulence Agents in Gram-Negative Bacteria. Antibiotics (Basel, Switzerland) 11 (2) (2022)
Ahmad J Almalki, Tarek S Ibrahim, Sameh S Elhady, Wael A H Hegazy, Khaled M Darwish
Computational and Biological Evaluation of β -Adrenoreceptor Blockers as Promising Bacterial Anti-Virulence Agents. Pharmaceuticals (Basel, Switzerland) 15 (2) (2022)
Hossam Mohamed Abdallah, Ali M El Halawany, Khaled M Darwish, Mardi M Algandaby, Gamal Abdallah Mohamed, Sabrin Ragab Mohamed Ibrahim, Abdulrahman E Koshak, Sameh S Elhady, Sana A Fadil, Ali A Alqarni, Ashraf B Abdel-Naim, Mahmoud A Elfaky
Bio-Guided Isolation of SARS-CoV-2 Main Protease Inhibitors from Medicinal Plants: In Vitro Assay and Molecular Dynamics. Plants (Basel, Switzerland) 11 (15) (2022)
Maan T Khayat, Tarek S Ibrahim, Khaled M Darwish, Ahdab N Khayyat, Majed Alharbi, El-Sayed Khafagy, Mohamed A M Ali, Wael A H Hegazy, Hisham A Abbas
Hiring of the Anti-Quorum Sensing Activities of Hypoglycemic Agent Linagliptin to Alleviate the Pseudomonas aeruginosa Pathogenesis. Microorganisms 10 (12) (2022)
Maan T Khayat, Tarek S Ibrahim, Khaled M Darwish, Ahdab N Khayyat, Majed Alharbi, El-Sayed Khafagy, Mohamed A M Ali, Wael A H Hegazy, Hisham A Abbas
Hiring of the Anti-Quorum Sensing Activities of Hypoglycemic Agent Linagliptin to Alleviate the Pseudomonas aeruginosa Pathogenesis. Microorganisms 10 (12) (2022)
Maan T Khayat, Tarek S Ibrahim, Khaled M Darwish, Ahdab N Khayyat, Majed Alharbi, El-Sayed Khafagy, Mohamed A M Ali, Wael A H Hegazy, Hisham A Abbas
Hiring of the Anti-Quorum Sensing Activities of Hypoglycemic Agent Linagliptin to Alleviate the Pseudomonas aeruginosa Pathogenesis. Microorganisms 10 (12) (2022)
Maan T Khayat, Hisham A Abbas, Tarek S Ibrahim, Ahdab N Khayyat, Majed Alharbi, Khaled M Darwish, Sameh S Elhady, El-Sayed Khafagy, Martin K Safo, Wael A H Hegazy
Anti-Quorum Sensing Activities of Gliptins against Pseudomonas aeruginosa and Staphylococcus aureus . Biomedicines 10 (5) (2022)
Maan T Khayat, Tarek S Ibrahim, Khaled M Darwish, Ahdab N Khayyat, Majed Alharbi, El-Sayed Khafagy, Mohamed A M Ali, Wael A H Hegazy, Hisham A Abbas
Hiring of the Anti-Quorum Sensing Activities of Hypoglycemic Agent Linagliptin to Alleviate the Pseudomonas aeruginosa Pathogenesis. Microorganisms 10 (12) (2022)
Mohamed A Soltan, Muhammad Alaa Eldeen, Nada Elbassiouny, Hasnaa L Kamel, Kareem M Abdelraheem, Hanaa Abd El-Gayyed, Ahmed M Gouda, Mohammed F Sheha, Eman Fayad, Ola A Abu Ali, Khalid Abd El Ghany, Dalia A El-Damasy, Khaled M Darwish, Sameh S Elhady, Ashraf E Sileem
In Silico Designing of a Multitope Vaccine against Rhizopus microsporus with Potential Activity against Other Mucormycosis Causing Fungi. Cells 10 (11) (2021)
Manar I Nagy, Khaled M Darwish, Safaa M Kishk, Mohamed A Tantawy, Ali M Nasr, Mona K E Qushawy, Shady A Swidan, Samia M Mostafa, Ismail Salama
Design, Synthesis, Anticancer Activity, and Solid Lipid Nanoparticle Formulation of Indole- and Benzimidazole-Based Compounds as Pro-Apoptotic Agents Targeting Bcl-2 Protein. Pharmaceuticals (Basel, Switzerland) 14 (2) (2021)
Reda F A Abdelhameed, Amany K Ibrahim, Mahmoud A Elfaky, Eman S Habib, Mayada I Mahamed, Eman T Mehanna, Khaled M Darwish, Dina M Khodeer, Safwat A Ahmed, Sameh S Elhady
Antioxidant and Anti-Inflammatory Activity of Cynanchum acutum L. Isolated Flavonoids Using Experimentally Induced Type 2 Diabetes Mellitus: Biological and In Silico Investigation for NF-κB Pathway/miR-146a Expression Modulation. Antioxidants (Basel, Switzerland) 10 (11) (2021)
Sameh S Elhady, Reda F A Abdelhameed, Rania T Malatani, Abdulrahman M Alahdal, Hanin A Bogari, Ahmad J Almalki, Khadijah A Mohammad, Safwat A Ahmed, Amgad I M Khedr, Khaled M Darwish
Molecular Docking and Dynamics Simulation Study of Hyrtios erectus Isolated Scalarane Sesterterpenes as Potential SARS-CoV-2 Dual Target Inhibitors. Biology 10 (5) (2021)
Ayman Abo Elmaaty, Khaled M Darwish, Amani Chrouda, Amira A Boseila, Mohamed A Tantawy, Sameh S Elhady, Afzal Basha Shaik, Muhamad Mustafa, Ahmed Ali Al-Karmalawy
In Silico and In Vitro Studies for Benzimidazole Anthelmintics Repurposing as VEGFR-2 Antagonists: Novel Mebendazole-Loaded Mixed Micelles with Enhanced Dissolution and Anticancer Activity. ACS omega 7 (1) (2021)
Sameh S Elhady, Reda F A Abdelhameed, Salwa H Zekry, Amany K Ibrahim, Eman S Habib, Khaled M Darwish, Reem M Hazem, Khadijah A Mohammad, Hashim A Hassanean, Safwat A Ahmed
VEGFR-Mediated Cytotoxic Activity of Pulicaria undulata Isolated Metabolites: A Biological Evaluation and In Silico Study. Life (Basel, Switzerland) 11 (8) (2021)
Mohammed W Al-Rabia, Nabil Abdulhafiz Alhakamy, Osama Abdelhakim Aly Ahmed, Khalid Eljaaly, Ahmed L Alaofi, Ahmed Mostafa, Hani Z Asfour, Ahmed A Aldarmahi, Khaled M Darwish, Tarek S Ibrahim, Usama Ahmed Fahmy
Repurposing of Sitagliptin- Melittin Optimized Nanoformula against SARS-CoV-2: Antiviral Screening and Molecular Docking Studies. Pharmaceutics 13 (3) (2021)
Azizah M Malebari, Tarek S Ibrahim, Ibrahim M Salem, Ismail Salama, Ahdab N Khayyat, Samia M Mostafa, Khaled M Darwish, Khaled M Darwish
The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme. Pharmaceuticals (Basel, Switzerland) 13 (9) (2020)

Khaled M Darwish.css-eqlu8i{font-size:small;padding-left:4px;} (Osama I El-Sabbagh)

Publication Activity (10 Years)

Top Topics

Top Venues

Khaled M Darwish (Osama I El-Sabbagh)