Martin K Safo (M K Safo)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 36

Top Topics

Sickle Cell Disease

Molecular Docking

Top Venues

Molecules (Basel, Switzerland)

Life (Basel, Switzerland)

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Piyusha P Pagare, Mina McGinn, Mohini S Ghatge, Vibha Shekhar, Rana T Alhashimi, B Daniel Pierce, Osheiza Abdulmalik, Yan Zhang, Martin K Safo
The antisickling agent, 5-hydroxymethyl-2-furfural: Other potential pharmacological applications. Medicinal research reviews (2024)
Angela Tramonti, Akua K Donkor, Alessia Parroni, Faik N Musayev, Anna Barile, Mohini S Ghatge, Claudio Graziani, Mona Alkhairi, Mohammed AlAwadh, Martino Luigi di Salvo, Martin K Safo, Roberto Contestabile
Functional and structural properties of pyridoxal reductase (PdxI) from Escherichia coli: a pivotal enzyme in the vitamin B6 salvage pathway. The FEBS journal (2023)
Maan T Khayat, Samar S Elbaramawi, Shaimaa I Nazeih, Martin K Safo, El-Sayed Khafagy, Mohamed A M Ali, Hisham A Abbas, Wael A H Hegazy, Noura M Seleem
Diminishing the Pathogenesis of the Food-Borne Pathogen Serratia marcescens by Low Doses of Sodium Citrate. Biology 12 (4) (2023)
Rana T Alhashimi, Tarek A Ahmed, Lamya Alghanem, Piyusha P Pagare, Boshi Huang, Mohini S Ghatge, Abdelsattar Mansour Omar Ebeid, Osheiza Abdulmalik, Yan Zhang, Martin K Safo
Design, Synthesis, and Antisickling Investigation of a Thiazolidine Prodrug of TD-7 That Prolongs the Duration of Action of Antisickling Aromatic Aldehyde. Pharmaceutics 15 (11) (2023)
Maan T Khayat, Samar S Elbaramawi, Shaimaa I Nazeih, Martin K Safo, El-Sayed Khafagy, Mohamed A M Ali, Hisham A Abbas, Wael A H Hegazy, Noura M Seleem
Diminishing the Pathogenesis of the Food-Borne Pathogen Serratia marcescens by Low Doses of Sodium Citrate. Biology 12 (4) (2023)
Mohammed H Al Mughram, Mohini S Ghatge, Glen E Kellogg, Martin K Safo
Elucidating the Interaction between Pyridoxine 5'-Phosphate Oxidase and Dopa Decarboxylase: Activation of B6-Dependent Enzyme. International journal of molecular sciences 24 (1) (2022)
Rana T Alhashimi, Mohini S Ghatge, Akua K Donkor, Tanvi M Deshpande, Nancy Anabaraonye, Dina Alramadhani, Richmond Danso-Danquah, Boshi Huang, Yan Zhang, Faik N Musayev, Osheiza Abdulmalik, Martin K Safo
Design, Synthesis, and Antisickling Investigation of a Nitric Oxide-Releasing Prodrug of 5HMF for the Treatment of Sickle Cell Disease. Biomolecules 12 (5) (2022)
Abdelsattar Mansour Omar Ebeid, Anfal S Aljahdali, Martin K Safo, Gamal Abdallah Mohamed, Sabrin Ragab Mohamed Ibrahim
Docking and Molecular Dynamic Investigations of Phenylspirodrimanes as Cannabinoid Receptor-2 Agonists. Molecules (Basel, Switzerland) 28 (1) (2022)
Mohammed H Al Mughram, Mohini S Ghatge, Glen E Kellogg, Martin K Safo
Elucidating the Interaction between Pyridoxine 5'-Phosphate Oxidase and Dopa Decarboxylase: Activation of B6-Dependent Enzyme. International journal of molecular sciences 24 (1) (2022)
Maan T Khayat, Khadijah A Mohammad, Gamal Abdallah Mohamed, Martin K Safo, Sabrin Ragab Mohamed Ibrahim
Integracides: Tetracyclic Triterpenoids from Fusarium sp.-Their 5-Lipoxygenase Inhibitory Potential and Structure-Activity Relation Using In Vitro and Molecular Docking Studies. Life (Basel, Switzerland) 12 (12) (2022)
Tarek A Ahmed, Hanadi A Alotaibi, Waleed S Alharbi, Martin K Safo, Khalid Mohamed El-Say
Development of 3D-Printed, Liquisolid and Directly Compressed Glimepiride Tablets, Loaded with Black Seed Oil Self-Nanoemulsifying Drug Delivery System: In Vitro and In Vivo Characterization. Pharmaceuticals (Basel, Switzerland) 15 (1) (2022)
Mohammed H Al Mughram, Mohini S Ghatge, Glen E Kellogg, Martin K Safo
Elucidating the Interaction between Pyridoxine 5'-Phosphate Oxidase and Dopa Decarboxylase: Activation of B6-Dependent Enzyme. International journal of molecular sciences 24 (1) (2022)
Abdelsattar Mansour Omar Ebeid, Anfal S Aljahdali, Martin K Safo, Gamal Abdallah Mohamed, Sabrin Ragab Mohamed Ibrahim
Docking and Molecular Dynamic Investigations of Phenylspirodrimanes as Cannabinoid Receptor-2 Agonists. Molecules (Basel, Switzerland) 28 (1) (2022)
Dina Alramadhani, Anfal S Aljahdali, Osheiza Abdulmalik, B Daniel Pierce, Martin K Safo
Metabolic Reprogramming in Sickle Cell Diseases: Pathophysiology and Drug Discovery Opportunities. International journal of molecular sciences 23 (13) (2022)
Maan T Khayat, Hisham A Abbas, Tarek S Ibrahim, Ahdab N Khayyat, Majed Alharbi, Khaled M Darwish, Sameh S Elhady, El-Sayed Khafagy, Martin K Safo, Wael A H Hegazy
Anti-Quorum Sensing Activities of Gliptins against Pseudomonas aeruginosa and Staphylococcus aureus . Biomedicines 10 (5) (2022)
Maan T Khayat, Khadijah A Mohammad, Gamal Abdallah Mohamed, Martin K Safo, Sabrin Ragab Mohamed Ibrahim
Integracides: Tetracyclic Triterpenoids from Fusarium sp.-Their 5-Lipoxygenase Inhibitory Potential and Structure-Activity Relation Using In Vitro and Molecular Docking Studies. Life (Basel, Switzerland) 12 (12) (2022)
Maan T Khayat, Khadijah A Mohammad, Gamal Abdallah Mohamed, Martin K Safo, Sabrin Ragab Mohamed Ibrahim
Integracides: Tetracyclic Triterpenoids from Fusarium sp.-Their 5-Lipoxygenase Inhibitory Potential and Structure-Activity Relation Using In Vitro and Molecular Docking Studies. Life (Basel, Switzerland) 12 (12) (2022)
Abdelsattar Mansour Omar Ebeid, Anfal S Aljahdali, Martin K Safo, Gamal Abdallah Mohamed, Sabrin Ragab Mohamed Ibrahim
Docking and Molecular Dynamic Investigations of Phenylspirodrimanes as Cannabinoid Receptor-2 Agonists. Molecules (Basel, Switzerland) 28 (1) (2022)
Maan T Khayat, Khadijah A Mohammad, Gamal Abdallah Mohamed, Martin K Safo, Sabrin Ragab Mohamed Ibrahim
Integracides: Tetracyclic Triterpenoids from Fusarium sp.-Their 5-Lipoxygenase Inhibitory Potential and Structure-Activity Relation Using In Vitro and Molecular Docking Studies. Life (Basel, Switzerland) 12 (12) (2022)
Boshi Huang, Mohini S Ghatge, Akua K Donkor, Faik N Musayev, Tanvi M Deshpande, Mohammed Al-Awadh, Rana T Alhashimi, Hongmei Zhu, Abdelsattar Mansour Omar Ebeid, Marilyn J Telen, Yan Zhang, Timothy J McMahon, Osheiza Abdulmalik, Martin K Safo
Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease. Molecules (Basel, Switzerland) 27 (20) (2022)
Tarek A Ahmed, Hanadi A Alotaibi, Alshaimaa M Almehmady, Martin K Safo, Khalid Mohamed El-Say
Influences of Glimepiride Self-Nanoemulsifying Drug Delivery System Loaded Liquisolid Tablets on the Hypoglycemic Activity and Pancreatic Histopathological Changes in Streptozotocin-Induced Hyperglycemic Rats. Nanomaterials (Basel, Switzerland) 12 (22) (2022)
Abdelsattar Mansour Omar Ebeid, Anfal S Aljahdali, Martin K Safo, Gamal Abdallah Mohamed, Sabrin Ragab Mohamed Ibrahim
Docking and Molecular Dynamic Investigations of Phenylspirodrimanes as Cannabinoid Receptor-2 Agonists. Molecules (Basel, Switzerland) 28 (1) (2022)
Tarek A Ahmed, Khalid Mohamed El-Say, Fathy I Abd-Allah, Abdelsattar Mansour Omar Ebeid, Moustafa E El-Araby, Yosra A Muhammad, Piyusha P Pagare, Yan Zhang, Khadijah A Mohmmad, Osheiza Abdulmalik, Martin K Safo
Improving the Solubility and Oral Bioavailability of a Novel Aromatic Aldehyde Antisickling Agent (PP10) for the Treatment of Sickle Cell Disease. Pharmaceutics 13 (8) (2021)
Alaa Sirwi, Nesrine S El Sayed, Hossam Mohamed Abdallah, Sabrin Ragab Mohamed Ibrahim, Gamal Abdallah Mohamed, Ali M El Halawany, Martin K Safo, Nora O Abdel Rasheed
Umuhengerin Neuroprotective Effects in Streptozotocin-Induced Alzheimer's Disease Mouse Model via Targeting Nrf2 and NF-Kβ Signaling Cascades. Antioxidants (Basel, Switzerland) 10 (12) (2021)
Sameh S Elhady, Reda F A Abdelhameed, Mayada M El-Ayouty, Amany K Ibrahim, Eman S Habib, Mohamed Saleh Elgawish, Hashim A Hassanean, Martin K Safo, Mohamed S Nafie, Safwat A Ahmed
New Antiproliferative Triflavanone from Thymelaea hirsuta-Isolation, Structure Elucidation and Molecular Docking Studies. Molecules (Basel, Switzerland) 26 (3) (2021)
Enas E Eltamany, Sameh S Elhady, Marwa S Goda, Omar M Aly, Eman S Habib, Amany K Ibrahim, Hashim A Hassanean, Usama Ramadan Abdelmohsen, Martin K Safo, Safwat A Ahmed
Chemical Composition of the Red Sea Green Algae Ulva lactuca : Isolation and In Silico Studies of New Anti-COVID-19 Ceramides. Metabolites 11 (12) (2021)
Mohammed H Al Mughram, Claudio Catalano, John P Bowry, Martin K Safo, J Neel Scarsdale, Glen E Kellogg
3D Interaction Homology: Hydropathic Analyses of the "π-Cation" and "π-π" Interaction Motifs in Phenylalanine, Tyrosine, and Tryptophan Residues. Journal of chemical information and modeling 61 (6) (2021)
Tarek A Ahmed, Alaa O Bawazir, Waleed S Alharbi, Martin K Safo
Enhancement of Simvastatin ex vivo Permeation from Mucoadhesive Buccal Films Loaded with Dual Drug Release Carriers. International journal of nanomedicine 15 (2020)
Abdelsattar Mansour Omar Ebeid, Osheiza Abdulmalik, Mohini S Ghatge, Yosra A Muhammad, Steven D Paredes, Moustafa E El-Araby, Martin K Safo
An Investigation of Structure-Activity Relationships of Azolylacryloyl Derivatives Yielded Potent and Long-Acting Hemoglobin Modulators for Reversing Erythrocyte Sickling. Biomolecules 10 (11) (2020)
Hossam M Abdallah, Dina S El-Agamy, Sabrin R M Ibrahim, Gamal A Mohamed, Wael M Elsaed, Amjad A Elghamdi, Martin K Safo, Azizah M Malebari
Euphorbia cuneata Represses LPS-induced Acute Lung Injury in Mice via its Antioxidative and Anti-inflammatory Activities. Plants (Basel, Switzerland) 9 (11) (2020)
Hossam Mohamed Abdallah, Mohamed A Farag, Mardi M Algandaby, Mohammed Zahid Nasrullah, Ashraf B Abdel-Naim, Basma G Eid, Martin K Safo, Abdulrahman E Koshak, Azizah M Malebari
Osteoprotective Activity and Metabolite Fingerprint via UPLC/MS and GC/MS of Lepidium sativum in Ovariectomized Rats. Nutrients 12 (7) (2020)
Piyusha P Pagare, Mohini S Ghatge, Qiukan Chen, Faik N Musayev, Jurgen Venitz, Osheiza Abdulmalik, Yan Zhang, Martin K Safo
Exploration of Structure-Activity Relationship of Aromatic Aldehydes Bearing Pyridinylmethoxy-Methyl Esters as Novel Antisickling Agents. Journal of medicinal chemistry 63 (23) (2020)
Khalid Mohamed El-Say, Osama Abdelhakim Aly Ahmed, Amir I Mohamed, Martin K Safo, Abdelsattar M Omar
Zein-alpha lipoic acid-loaded nanoparticles to enhance the oral bioavailability of dapoxetine: optimization and clinical pharmacokinetic evaluation. International journal of nanomedicine 14 (2019)
A M Omar, T David, P P Pagare, M S Ghatge, Q Chen, A Mehta, Y Zhang, O Abdulmalik, A H Naghi, M E El-Araby, Martin K Safo
Structural modification of azolylacryloyl derivatives yields a novel class of covalent modifiers of hemoglobin as potential antisickling agents. MedChemComm 10 (11) (2019)
Akito Nakagawa, Michele Ferrari, Grigorij Schleifer, Marissa K Cooper, Chen Liu, Binglan Yu, Lorenzo Berra, Elizabeth S Klings, Ronni S Safo, Qiukan Chen, Faik N Musayev, Martin K Safo, Osheiza Abdulmalik, Donald B Bloch, Warren M Zapol
A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells. Molecular pharmaceutics 15 (5) (2018)
Guoyan G Xu, Piyusha P Pagare, Mohini S Ghatge, Ronni P Safo, Aheema Gazi, Qiukan Chen, Tanya David, Alhumaidi B Alabbas, Faik N Musayev, Jürgen Venitz, Yan Zhang, Martin K Safo, Osheiza Abdulmalik
Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease. Molecular pharmaceutics 14 (10) (2017)