P Hande Özdinler (Hande Özdinler, P Hande Ozdinler)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 13

Top Topics

Amyotrophic Lateral Sclerosis

Top Venues

Neural regeneration research

Medicinal research reviews

This page only lists publications with an associated author ORCID identifier.

Publications

Benjamin R Helmold, Angela Ahrens, Zachary Fitzgerald, P Hande Özdinler
Spastin and alsin protein interactome analyses begin to reveal key canonical pathways and suggest novel druggable targets. Neural regeneration research 20 (3) (2024)
Mohamed F Elmansy, Cory T Reidl, Mizzanoor Rahaman, P Hande Özdinler, Richard B Silverman
Small molecules targeting different cellular pathologies for the treatment of amyotrophic lateral sclerosis. Medicinal research reviews (2023)
Barış Genç, Boram Nho, Hana Seung, Benjamin Helmold, Huiwon Park, Öge Gözütok, Seunghyun Kim, Jinil Park, Sanghyun Ye, Haneul Lee, Nayeon Lee, Seung-Shin Yu, Sunyoung Kim, Junghun Lee, P Hande Özdinler
Novel rAAV vector mediated intrathecal HGF delivery has an impact on neuroimmune modulation in the ALS motor cortex with TDP-43 pathology. Gene therapy (2023)
Mukesh Gautam, Renata Del Carratore, Benjamin Helmold, Alessandra Tessa, Oge Gozutok, Navdeep Chandel, Halil Idrisoglu, Paolo Bongioanni, Roberta Battini, P Hande Özdinler
2-Year-Old and 3-Year-Old Italian ALS Patients with Novel ALS2 Mutations: Identification of Key Metabolites in Their Serum and Plasma. Metabolites 12 (2) (2022)
Barış Genç, Mukesh Gautam, Öge Gözütok, Ina Dervishi, Santana Sanchez, Gashaw M Goshu, Nuran Koçak, Edward Xie, Richard B Silverman, P Hande Özdinler
Improving mitochondria and ER stability helps eliminate upper motor neuron degeneration that occurs due to mSOD1 toxicity and TDP-43 pathology. Clinical and translational medicine 11 (2) (2021)
Oge Gozutok, Benjamin Ryan Helmold, P Hande Özdinler
Mutations and Protein Interaction Landscape Reveal Key Cellular Events Perturbed in Upper Motor Neurons with HSP and PLS. Brain sciences 11 (5) (2021)
P Hande Özdinler
Help from peripheral macrophages in ALS? Nature neuroscience 23 (11) (2021)
Barış Genç, Javier H Jara, Santana S Sanchez, Amiko K B Lagrimas, Öge Gözütok, Nuran Koçak, Yongling Zhu, P Hande Özdinler
Upper motor neurons are a target for gene therapy and UCHL1 is necessary and sufficient to improve cellular integrity of diseased upper motor neurons. Gene therapy (2021)
Baris Genc, Oge Gozutok, Nuran Kocak, P Hande Özdinler
The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord. Cells 9 (2) (2020)
P Hande Özdinler
Expanded access: opening doors to personalized medicine for rare disease patients and patients with neurodegenerative diseases. The FEBS journal 288 (5) (2020)
Baris Genc, Oge Gozutok, P Hande Özdinler
Complexity of Generating Mouse Models to Study the Upper Motor Neurons: Let Us Shift Focus from Mice to Neurons. International journal of molecular sciences 20 (16) (2019)
Mukesh Gautam, Javier H Jara, Nuran Kocak, Lauren E Rylaarsdam, Ki Dong Kim, Eileen H Bigio, P Hande Özdinler
Mitochondria, ER, and nuclear membrane defects reveal early mechanisms for upper motor neuron vulnerability with respect to TDP-43 pathology. Acta neuropathologica 137 (1) (2018)
Javier H Jara, Barış Genç, Macdonell J Stanford, Peter Pytel, Raymond P Roos, Sandra Weintraub, M Marsel Mesulam, Eileen H Bigio, Richard J Miller, P Hande Özdinler
Evidence for an early innate immune response in the motor cortex of ALS. Journal of neuroinflammation 14 (1) (2017)