Paul Saftig

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 28

Top Venues

Nature communications

Cellular and molecular life sciences : CMLS

Nature cell biology

Autophagy

Christian-Albrechts-Universität zu Kiel

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Christian-Albrechts-Universität zu Kiel Feb 01 2002

Germany

Director :: Biochemical Institute

Publications

Katharina Esther Julia Jungnickel, Océane Guelle, Miharu Iguchi, Wentao Dong, Vadim Kotov, Florian Gabriel, Cécile Debacker, Julien Dairou, Isabelle McCort-Tranchepain, Nouf N Laqtom, Sze Ham Chan, Akika Ejima, Kenji Sato, David Massa López, Paul Saftig, Ahmad Reza Mehdipour, Monther Abu-Remaileh, Bruno Gasnier, Christian Löw, Markus Damme
MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes. Nature cell biology 26 (7) (2024)
Julia Bär, Tomas Fanutza, Christopher C Reimann, Lisa Seipold, Maja Grohe, Janike Rabea Bolter, Flemming Delfs, Michael Bucher, Christine Elizabeth Gee, Michaela Schweizer, Paul Saftig, Marina Mikhaylova
Non-canonical function of ADAM10 in presynaptic plasticity. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Katharina Esther Julia Jungnickel, Océane Guelle, Miharu Iguchi, Wentao Dong, Vadim Kotov, Florian Gabriel, Cécile Debacker, Julien Dairou, Isabelle McCort-Tranchepain, Nouf N Laqtom, Sze Ham Chan, Akika Ejima, Kenji Sato, David Massa López, Paul Saftig, Ahmad Reza Mehdipour, Monther Abu-Remaileh, Bruno Gasnier, Christian Löw, Markus Damme
MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes. Nature cell biology 26 (7) (2024)
Katharina Esther Julia Jungnickel, Océane Guelle, Miharu Iguchi, Wentao Dong, Vadim Kotov, Florian Gabriel, Cécile Debacker, Julien Dairou, Isabelle McCort-Tranchepain, Nouf N Laqtom, Sze Ham Chan, Akika Ejima, Kenji Sato, David Massa López, Paul Saftig, Ahmad Reza Mehdipour, Monther Abu-Remaileh, Bruno Gasnier, Christian Löw, Markus Damme
MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes. Nature cell biology 26 (7) (2024)
Julia Bär, Tomas Fanutza, Christopher C Reimann, Lisa Seipold, Maja Grohe, Janike Rabea Bolter, Flemming Delfs, Michael Bucher, Christine Elizabeth Gee, Michaela Schweizer, Paul Saftig, Marina Mikhaylova
Non-canonical function of ADAM10 in presynaptic plasticity. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Katharina Esther Julia Jungnickel, Océane Guelle, Miharu Iguchi, Wentao Dong, Vadim Kotov, Florian Gabriel, Cécile Debacker, Julien Dairou, Isabelle McCort-Tranchepain, Nouf N Laqtom, Sze Ham Chan, Akika Ejima, Kenji Sato, David Massa López, Paul Saftig, Ahmad Reza Mehdipour, Monther Abu-Remaileh, Bruno Gasnier, Christian Löw, Markus Damme
MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes. Nature cell biology 26 (7) (2024)
Julia Bär, Tomas Fanutza, Christopher C Reimann, Lisa Seipold, Maja Grohe, Janike Rabea Bolter, Flemming Delfs, Michael Bucher, Christine Elizabeth Gee, Michaela Schweizer, Paul Saftig, Marina Mikhaylova
Non-canonical function of ADAM10 in presynaptic plasticity. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Lisa Gallwitz, Florian Bleibaum, Matthias Voss, Michaela Schweizer, Katharina Spengler, Dominic Winter, Frederic Zöphel, Stephan Müller, Stefan Lichtenthaler, Markus Damme, Paul Saftig
Cellular depletion of major cathepsin proteases reveals their concerted activities for lysosomal proteolysis. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Katharina Esther Julia Jungnickel, Océane Guelle, Miharu Iguchi, Wentao Dong, Vadim Kotov, Florian Gabriel, Cécile Debacker, Julien Dairou, Isabelle McCort-Tranchepain, Nouf N Laqtom, Sze Ham Chan, Akika Ejima, Kenji Sato, David Massa López, Paul Saftig, Ahmad Reza Mehdipour, Monther Abu-Remaileh, Bruno Gasnier, Christian Löw, Markus Damme
MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes. Nature cell biology (2024)
Lisa Gallwitz, Florian Bleibaum, Matthias Voss, Michaela Schweizer, Katharina Spengler, Dominic Winter, Frederic Zöphel, Stephan Müller, Stefan Lichtenthaler, Markus Damme, Paul Saftig
Cellular depletion of major cathepsin proteases reveals their concerted activities for lysosomal proteolysis. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Julia Becker, Ariane Schleinitz, Christina Hermsen, Sabrina Rappold, Paul Saftig, Andreas Jeschke, Albert Haas
Rab GTPase-regulated phagosome-lysosome fusion is bypassed by micromolar calcium. Journal of cell science (2023)
David Rosenbaum, Paul Saftig
New insights into the function and pathophysiology of the ectodomain sheddase A Disintegrin And Metalloproteinase 10 (ADAM10). The FEBS journal (2023)
Erik Klapproth, Anke Witt, Pauline Klose, Johanna Wiedemann, Nikitha Vavilthota, Stephan R Künzel, Susanne Kämmerer, Mario Günscht, David Sprott, Matthias Lesche, Fabian Rost, Andreas Dahl, Erik Rauch, Lars Kattner, Silvio Weber, Peter Mirtschink, Irakli Kopaliani, Kaomei Guan, Kristina Lorenz, Paul Saftig, Michael Wagner, Ali El-Armouche
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction. Nature communications 13 (1) (2022)
Erik Klapproth, Anke Witt, Pauline Klose, Johanna Wiedemann, Nikitha Vavilthota, Stephan R Künzel, Susanne Kämmerer, Mario Günscht, David Sprott, Matthias Lesche, Fabian Rost, Andreas Dahl, Erik Rauch, Lars Kattner, Silvio Weber, Peter Mirtschink, Irakli Kopaliani, Kaomei Guan, Kristina Lorenz, Paul Saftig, Michael Wagner, Ali El-Armouche
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction. Nature communications 13 (1) (2022)
Barbara Spix, Elisabeth S Butz, Cheng-Chang Chen, Anna Scotto Rosato, Rachel Tang, Aicha Jeridi, Veronika Kudrina, Eva Plesch, Philipp Wartenberg, Elisabeth Arlt, Daria Briukhovetska, Meshal Ansari, Gizem Günes Günsel, Thomas M Conlon, Amanda Wyatt, Sandra Wetzel, Daniel Teupser, Lesca M Holdt, Fabien Ectors, Ingrid Boekhoff, Ulrich Boehm, Jaime García-Añoveros, Paul Saftig, Martin A Giera, Sebastian Kobold, Herbert B Schiller, Susanna Zierler, Thomas Gudermann, Christian Wahl-Schott, Franz Bracher, Ali Oender Yildirim, Martin Biel, Christian M Grimm
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice. Nature communications 13 (1) (2022)
Erik Klapproth, Anke Witt, Pauline Klose, Johanna Wiedemann, Nikitha Vavilthota, Stephan R Künzel, Susanne Kämmerer, Mario Günscht, David Sprott, Matthias Lesche, Fabian Rost, Andreas Dahl, Erik Rauch, Lars Kattner, Silvio Weber, Peter Mirtschink, Irakli Kopaliani, Kaomei Guan, Kristina Lorenz, Paul Saftig, Michael Wagner, Ali El-Armouche
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction. Nature communications 13 (1) (2022)
Torben Mentrup, Anna Yamina Stumpff-Niggemann, Nadja Leinung, Christine Schlosser, Katja Schubert, Rebekka Wehner, Antje Tunger, Valentin Schatz, Patrick Neubert, Ann-Christine Gradtke, Janina Wolf, Stefan Rose-John, Paul Saftig, Alexander Dalpke, Jonathan Jantsch, Marc Schmitz, Regina Fluhrer, Ilse D Jacobsen, Bernd Schröder
Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis. Nature communications 13 (1) (2022)
Pedro M Rodrigues, Laura G Sousa, Chiara Perrod, Ana R Maceiras, Pedro Ferreirinha, Rita Pombinho, Gema Romera-Cárdenas, María Gomez-Lazaro, Meryem Senkara, Jelena Pistolic, Didier Cabanes, Ludger Klein, Paul Saftig, Martin R Goodier
LAMP2 regulates autophagy in the thymic epithelium and thymic stroma-dependent CD4 T cell development. Autophagy (2022)
Erik Klapproth, Anke Witt, Pauline Klose, Johanna Wiedemann, Nikitha Vavilthota, Stephan R Künzel, Susanne Kämmerer, Mario Günscht, David Sprott, Matthias Lesche, Fabian Rost, Andreas Dahl, Erik Rauch, Lars Kattner, Silvio Weber, Peter Mirtschink, Irakli Kopaliani, Kaomei Guan, Kristina Lorenz, Paul Saftig, Michael Wagner, Ali El-Armouche
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction. Nature communications 13 (1) (2022)
Erik Klapproth, Anke Witt, Pauline Klose, Johanna Wiedemann, Nikitha Vavilthota, Stephan R Künzel, Susanne Kämmerer, Mario Günscht, David Sprott, Matthias Lesche, Fabian Rost, Andreas Dahl, Erik Rauch, Lars Kattner, Silvio Weber, Peter Mirtschink, Irakli Kopaliani, Kaomei Guan, Kristina Lorenz, Paul Saftig, Michael Wagner, Ali El-Armouche
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction. Nature communications 13 (1) (2022)
Erik Klapproth, Anke Witt, Pauline Klose, Johanna Wiedemann, Nikitha Vavilthota, Stephan R Künzel, Susanne Kämmerer, Mario Günscht, David Sprott, Matthias Lesche, Fabian Rost, Andreas Dahl, Erik Rauch, Lars Kattner, Silvio Weber, Peter Mirtschink, Irakli Kopaliani, Kaomei Guan, Kristina Lorenz, Paul Saftig, Michael Wagner, Ali El-Armouche
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction. Nature communications 13 (1) (2022)
Susy Prieto Huarcaya, Alice Drobny, André R A Marques, Alessandro Di Spiezio, Jan Philipp Dobert, Denise Balta, Christian Werner, Tania Rizo, Lisa Gallwitz, Simon Bub, Iva Stojkovska, Nandkishore R Belur, Jens Fogh, Joseph R Mazzulli, Wei Xiang, Amitkumar Fulzele, Mario Dejung, Markus Sauer, Beate Winner, Stefan Rose-John, Philipp Arnold, Paul Saftig, Friederike Zunke
Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models. Autophagy 18 (5) (2022)
Sönke Rudnik, Saskia Heybrock, Paul Saftig, Markus Damme
S-palmitoylation determines TMEM55B-dependent positioning of lysosomes. Journal of cell science 135 (5) (2021)
Julia Bolik, Freia Krause, Marija Stevanovic, Monja Gandraß, Ilka Thomsen, Sarah-Sophie Schacht, Eva Rieser, Miryam Müller, Neele Schumacher, Jürgen Fritsch, Rielana Wichert, Eithan Galun, Juri Bergmann, Christian Röder, Clemens Schafmayer, Jan-Hendrik Egberts, Christoph Becker-Pauly, Paul Saftig, Ralph Lucius, Wulf Schneider-Brachert, Roja Barikbin, Dieter Adam, Matthias Voss, Wolfgang Hitzl, Achim Krüger, Boris Strilic, Irit Sagi, Henning Walczak, Stefan Rose-John, Dirk Schmidt-Arras
Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis. The Journal of experimental medicine 219 (1) (2021)
André R A Marques, Paul Saftig
Lysosomal storage disorders - challenges, concepts and avenues for therapy: beyond rare diseases. Journal of cell science 132 (2) (2019)
Johannes Niemeyer, Torben Mentrup, Ronny Heidasch, Stephan A Müller, Uddipta Biswas, Rieke Meyer, Alkmini A Papadopoulou, Verena Dederer, Martina Haug-Kröper, Vivian Adamski, Renate Lüllmann-Rauch, Martin Bergmann, Artur Mayerhofer, Paul Saftig, Gunther Wennemuth, Rolf Jessberger, Regina Fluhrer, Stefan F Lichtenthaler, Marius K Lemberg, Bernd Schröder
The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban. EMBO reports 20 (3) (2019)
André R A Marques, Alessandro Di Spiezio, Niklas Thießen, Lina Schmidt, Joachim Grötzinger, Renate Lüllmann-Rauch, Markus Damme, Steffen E Storck, Claus U Pietrzik, Jens Fogh, Julia Bär, Marina Mikhaylova, Markus Glatzel, Mahmoud Bassal, Udo Bartsch, Paul Saftig
Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis. Autophagy 16 (5) (2019)
Sandra Markmann, Svenja Krambeck, Christopher J Hughes, Mina Mirzaian, Johannes M F G Aerts, Paul Saftig, Michaela Schweizer, Johannes P C Vissers, Thomas Braulke, Markus Damme
Quantitative Proteome Analysis of Mouse Liver Lysosomes Provides Evidence for Mannose 6-phosphate-independent Targeting Mechanisms of Acid Hydrolases in Mucolipidosis II. Molecular & cellular proteomics : MCP 16 (3) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Paul Saftig