Cong Liu

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 88

Top Venues

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

Cell research

Cell death & disease

Interdisciplinary Research Center for Biology and Chemistry

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Interdisciplinary Research Center for Biology and Chemistry

China

Principle investigator

University of California, Los Angeles

United States

Post-doc

Publications

Wanbing Zhao, Kaien Liu, Yun Fan, Qinyue Zhao, Youqi Tao, Mengwei Zhang, Linhua Gan, Wenbo Yu, Bo Sun, Dan Li, Cong Liu, Jian Wang
Cryo-EM structures reveal variant Tau amyloid fibrils between the rTg4510 mouse model and sporadic human tauopathies. Cell discovery 10 (1) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Author Correction: Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Jinjian Hu, Wencheng Xia, Shuyi Zeng, Yeh-Jun Lim, Youqi Tao, Yunpeng Sun, Lang Zhao, Haosen Wang, Wei-Dong Le, Dan Li, Shengnan Zhang, Cong Liu, Yan-Mei Li
Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures. Nature communications 15 (1) (2024)
Kaien Liu, Youqi Tao, Qinyue Zhao, Wencheng Xia, Xiang Li, Shenqing Zhang, Yuxuan Yao, Huaijiang Xiang, Chao Han, Li Tan, Bo Sun, Dan Li, Ang Li, Cong Liu
Binding adaptability of chemical ligands to polymorphic α-synuclein amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Shuang Hou, Jiaojiao Hu, Zhaowei Yu, Dan Li, Cong Liu, Yong Zhang
Machine learning predictor PSPire screens for phase-separating proteins lacking intrinsically disordered regions. Nature communications 15 (1) (2024)
Kaien Liu, Youqi Tao, Qinyue Zhao, Wencheng Xia, Xiang Li, Shenqing Zhang, Yuxuan Yao, Huaijiang Xiang, Chao Han, Li Tan, Bo Sun, Dan Li, Ang Li, Cong Liu
Binding adaptability of chemical ligands to polymorphic α-synuclein amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Jiaojiao Hu, Hui Dong, Yichen Li, Jinge Gu, Liang Yang, Chenfang Si, Yaoyang Zhang, Tingting Li, Dan Li, Cong Liu
Hsp90α forms condensate engaging client proteins with RG motif repeats. Chemical science 15 (27) (2024)
Jiaojiao Hu, Hui Dong, Yichen Li, Jinge Gu, Liang Yang, Chenfang Si, Yaoyang Zhang, Tingting Li, Dan Li, Cong Liu
Hsp90α forms condensate engaging client proteins with RG motif repeats. Chemical science 15 (27) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Shuang Hou, Jiaojiao Hu, Zhaowei Yu, Dan Li, Cong Liu, Yong Zhang
Machine learning predictor PSPire screens for phase-separating proteins lacking intrinsically disordered regions. Nature communications 15 (1) (2024)
Chuchu Wang, Kai Zhang, Bin Cai, Jillian E Haller, Kathryn E Carnazza, Jiaojiao Hu, Chunyu Zhao, Zhiqi Tian, Xiao Hu, Daniel Hall, Jiali Qiang, Shouqiao Hou, Zhenying Liu, Jinge Gu, Yao-Yang Zhang, Kim B Seroogy, Jacqueline Burré, Yanshan Fang, Cong Liu, Axel T Brunger, Dan Li, Jiajie Diao
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates. Nature cell biology (2024)
Yanan Li, Chao Liu, Xinshuo Jia, Lulu Bi, Zhiyun Ren, Yilin Zhao, Xia Zhang, Lijuan Guo, Yanling Bao, Cong Liu, Wei Li, Bo Sun
RPA transforms RNase H1 to a bidirectional exoribonuclease for processive RNA-DNA hybrid cleavage. Nature communications 15 (1) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Kaien Liu, Youqi Tao, Qinyue Zhao, Wencheng Xia, Xiang Li, Shenqing Zhang, Yuxuan Yao, Huaijiang Xiang, Chao Han, Li Tan, Bo Sun, Dan Li, Ang Li, Cong Liu
Binding adaptability of chemical ligands to polymorphic α-synuclein amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Yanan Li, Chao Liu, Xinshuo Jia, Lulu Bi, Zhiyun Ren, Yilin Zhao, Xia Zhang, Lijuan Guo, Yanling Bao, Cong Liu, Wei Li, Bo Sun
RPA transforms RNase H1 to a bidirectional exoribonuclease for processive RNA-DNA hybrid cleavage. Nature communications 15 (1) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Qinyue Zhao, Yun Fan, Wanbing Zhao, You Ni, Youqi Tao, Jiang Bian, Wencheng Xia, Wenbo Yu, Zhen Fan, Cong Liu, Bo Sun, Weidong Le, Wensheng Li, Jian Wang, Dan Li
A Tau PET tracer PBB3 binds to TMEM106B amyloid fibril in brain. Cell discovery 10 (1) (2024)
Qinyue Zhao, Yun Fan, Wanbing Zhao, You Ni, Youqi Tao, Jiang Bian, Wencheng Xia, Wenbo Yu, Zhen Fan, Cong Liu, Bo Sun, Weidong Le, Wensheng Li, Jian Wang, Dan Li
A Tau PET tracer PBB3 binds to TMEM106B amyloid fibril in brain. Cell discovery 10 (1) (2024)
Hang Sun, Bingwei Yang, Qiong Li, Xiaokang Zhu, Erqun Song, Cong Liu, Yang Song, Guibin Jiang
Polystyrene nanoparticles trigger aberrant condensation of TDP-43 and amyotrophic lateral sclerosis-like symptoms. Nature nanotechnology (2024)
Jinjian Hu, Wencheng Xia, Shuyi Zeng, Yeh-Jun Lim, Youqi Tao, Yunpeng Sun, Lang Zhao, Haosen Wang, Wei-Dong Le, Dan Li, Shengnan Zhang, Cong Liu, Yan-Mei Li
Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures. Nature communications 15 (1) (2024)
Hong Zhang, Huazhang Guo, Danni Li, Yiling Zhang, Shengnan Zhang, Wenyan Kang, Cong Liu, Wei-Dong Le, Liang Wang, Dan Li, Bin Dai
Halogen doped graphene quantum dots modulate TDP-43 phase separation and aggregation in the nucleus. Nature communications 15 (1) (2024)
Qianhui Xu, Huilan Wang, Ruonan Yang, Youqi Tao, Ziying Wang, Shengnan Zhang, Bo Sun, Dan Li, Boxun Lu, Cong Liu
α-Synuclein amyloid fibril directly binds to LC3B and suppresses SQSTM1/p62-mediated selective autophagy. Cell research (2024)
Wanbing Zhao, Kaien Liu, Yun Fan, Qinyue Zhao, Youqi Tao, Mengwei Zhang, Linhua Gan, Wenbo Yu, Bo Sun, Dan Li, Cong Liu, Jian Wang
Cryo-EM structures reveal variant Tau amyloid fibrils between the rTg4510 mouse model and sporadic human tauopathies. Cell discovery 10 (1) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Hong Zhang, Huazhang Guo, Danni Li, Yiling Zhang, Shengnan Zhang, Wenyan Kang, Cong Liu, Wei-Dong Le, Liang Wang, Dan Li, Bin Dai
Halogen doped graphene quantum dots modulate TDP-43 phase separation and aggregation in the nucleus. Nature communications 15 (1) (2024)
Chuchu Wang, Chunyu Zhao, Xiao Hu, Jiali Qiang, Zhenying Liu, Jinge Gu, Shengnan Zhang, Dan Li, Yaoyang Zhang, Jacqueline Burré, Jiajie Diao, Cong Liu
N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine. bioRxiv : the preprint server for biology (2024)
Wanbing Zhao, Kaien Liu, Yun Fan, Qinyue Zhao, Youqi Tao, Mengwei Zhang, Linhua Gan, Wenbo Yu, Bo Sun, Dan Li, Cong Liu, Jian Wang
Cryo-EM structures reveal variant Tau amyloid fibrils between the rTg4510 mouse model and sporadic human tauopathies. Cell discovery 10 (1) (2024)
Jinjian Hu, Wencheng Xia, Shuyi Zeng, Yeh-Jun Lim, Youqi Tao, Yunpeng Sun, Lang Zhao, Haosen Wang, Wei-Dong Le, Dan Li, Shengnan Zhang, Cong Liu, Yan-Mei Li
Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures. Nature communications 15 (1) (2024)
Chuchu Wang, Kai Zhang, Bin Cai, Jillian E Haller, Kathryn E Carnazza, Jiaojiao Hu, Chunyu Zhao, Zhiqi Tian, Xiao Hu, Daniel Hall, Jiali Qiang, Shouqiao Hou, Zhenying Liu, Jinge Gu, Yao-Yang Zhang, Kim B Seroogy, Jacqueline Burré, Yanshan Fang, Cong Liu, Axel T Brunger, Dan Li, Jiajie Diao
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates. Nature cell biology 26 (8) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Chuchu Wang, Chunyu Zhao, Xiao Hu, Jiali Qiang, Zhenying Liu, Jinge Gu, Shengnan Zhang, Dan Li, Yaoyang Zhang, Jacqueline Burré, Jiajie Diao, Cong Liu
N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine. bioRxiv : the preprint server for biology (2024)
Hong Zhang, Huazhang Guo, Danni Li, Yiling Zhang, Shengnan Zhang, Wenyan Kang, Cong Liu, Wei-Dong Le, Liang Wang, Dan Li, Bin Dai
Halogen doped graphene quantum dots modulate TDP-43 phase separation and aggregation in the nucleus. Nature communications 15 (1) (2024)
Shuang Hou, Jiaojiao Hu, Zhaowei Yu, Dan Li, Cong Liu, Yong Zhang
Machine learning predictor PSPire screens for phase-separating proteins lacking intrinsically disordered regions. Nature communications 15 (1) (2024)
Kaien Liu, Youqi Tao, Qinyue Zhao, Wencheng Xia, Xiang Li, Shenqing Zhang, Yuxuan Yao, Huaijiang Xiang, Chao Han, Li Tan, Bo Sun, Dan Li, Ang Li, Cong Liu
Binding adaptability of chemical ligands to polymorphic α-synuclein amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Author Correction: Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Shengnan Zhang, Juan Li, Qianhui Xu, Wencheng Xia, Youqi Tao, Chaowei Shi, Dan Li, ShengQi Xiang, Cong Liu
Conformational Dynamics of an α-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy. Journal of the American Chemical Society (2023)
Zhaofei Yang, Ying Wang, Min Wei, Song Li, Congcong Jia, Cheng Cheng, Murad Al-Nusaif, Jun Zhang, Cong Liu, Wei-Dong Le
Intrastriatal injection of Parkinson's disease intestine and vagus lysates initiates α-synucleinopathy in rat brain. Cell death & disease 14 (1) (2023)
Fenghua Wang, Wencheng Xia, Mingming Zhang, Rongrong Wu, Xiaolu Song, Yun Hao, Yonghai Feng, Liwei Zhang, Dan Li, Wenyan Kang, Cong Liu, Lei Liu
Engineering of antimicrobial peptide fibrils with feedback degradation of bacterial-secreted enzymes. Chemical science 14 (39) (2023)
Zhaofei Yang, Ying Wang, Min Wei, Song Li, Congcong Jia, Cheng Cheng, Murad Al-Nusaif, Jun Zhang, Cong Liu, Wei-Dong Le
Intrastriatal injection of Parkinson's disease intestine and vagus lysates initiates α-synucleinopathy in rat brain. Cell death & disease 14 (1) (2023)
Yulong Bai, Shengnan Zhang, Hui Dong, Liu Yu, Cong Liu, Zhang Xin
Advanced Techniques for Detecting Protein Misfolding and Aggregation in Cellular Environments. Chemical reviews (2023)
Zhaofei Yang, Ying Wang, Min Wei, Song Li, Congcong Jia, Cheng Cheng, Murad Al-Nusaif, Jun Zhang, Cong Liu, Wei-Dong Le
Intrastriatal injection of Parkinson's disease intestine and vagus lysates initiates α-synucleinopathy in rat brain. Cell death & disease 14 (1) (2023)
Xinyu Wang, Shengnan Zhang, Jicong Zhang, Yaomin Wang, Xiaoyu Jiang, Youqi Tao, Dan Li, Chao Zhong, Cong Liu
Rational design of functional amyloid fibrillar assemblies. Chemical Society reviews (2023)
Shengnan Zhang, Juan Li, Qianhui Xu, Wencheng Xia, Youqi Tao, Chaowei Shi, Dan Li, ShengQi Xiang, Cong Liu
Conformational Dynamics of an α-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy. Journal of the American Chemical Society 145 (8) (2023)
Hong Zhang, Jinge Gu, Yiling Zhang, Huazhang Guo, Shengnan Zhang, Jie Song, Cong Liu, Liang Wang, Dan Li, Bin Dai
Graphene Quantum Dots Modulate Stress Granule Assembly and Prevent Abnormal Phase Transition of Fused in Sarcoma Protein. ACS nano (2023)
Yini Zhao, Qiuyang Zheng, Yujuan Hong, Yue Gao, Jiaojiao Hu, Maoju Lang, Hongfeng Zhang, Ying Zhou, Hong Luo, Xian Zhang, Hao Sun, Xiao-Xin Yan, Timothy Y Huang, Yan-Jiang Wang, Huaxi Xu, Cong Liu, Xin Wang
β 2 -Microglobulin coaggregates with Aβ and contributes to amyloid pathology and cognitive deficits in Alzheimer's disease model mice. Nature neuroscience (2023)
Zhaofei Yang, Ying Wang, Min Wei, Song Li, Congcong Jia, Cheng Cheng, Murad Al-Nusaif, Jun Zhang, Cong Liu, Wei-Dong Le
Intrastriatal injection of Parkinson's disease intestine and vagus lysates initiates α-synucleinopathy in rat brain. Cell death & disease 14 (1) (2023)
Ying Lai, Chunyu Zhao, Zhiqi Tian, Chuchu Wang, Jiaqi Fan, Xiao Hu, Jia Tu, Tihui Li, Jeremy Leitz, Richard A Pfuetzner, Zhengtao Liu, Shengnan Zhang, Zhaoming Su, Jacqueline Burré, Dan Li, Thomas C Südhof, Zheng-Jiang Zhu, Cong Liu, Axel T Brunger, Jiajie Diao
Neutral lysophosphatidylcholine mediates α-synuclein-induced synaptic vesicle clustering. Proceedings of the National Academy of Sciences of the United States of America 120 (44) (2023)
Youqi Tao, Wencheng Xia, Qinyue Zhao, Huaijiang Xiang, Chao Han, Shenqing Zhang, Wei Gu, Wenjun Tang, Ying Li, Li Tan, Dan Li, Cong Liu
Structural mechanism for specific binding of chemical compounds to amyloid fibrils. Nature chemical biology (2023)
Shengnan Zhang, Juan Li, Qianhui Xu, Wencheng Xia, Youqi Tao, Chaowei Shi, Dan Li, ShengQi Xiang, Cong Liu
Conformational Dynamics of an α-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy. Journal of the American Chemical Society 145 (8) (2023)
Zhaofei Yang, Ying Wang, Min Wei, Song Li, Congcong Jia, Cheng Cheng, Murad Al-Nusaif, Jun Zhang, Cong Liu, Wei-Dong Le
Intrastriatal injection of Parkinson's disease intestine and vagus lysates initiates α-synucleinopathy in rat brain. Cell death & disease 14 (1) (2023)
Yun Fan, Qinyue Zhao, Wencheng Xia, Youqi Tao, Wenbo Yu, Mingjia Chen, Yiqi Liu, Jue Zhao, Yan Shen, Yunpeng Sun, Chenfang Si, Shenqing Zhang, Yao-Yang Zhang, Wensheng Li, Cong Liu, Jian Wang, Dan Li
Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders. Cell research 32 (6) (2022)
Youqi Tao, Yunpeng Sun, Shiran Lv, Wencheng Xia, Kun Zhao, Qianhui Xu, Qinyue Zhao, Lin He, Wei-Dong Le, Yong Wang, Cong Liu, Dan Li
Heparin induces α-synuclein to form new fibril polymorphs with attenuated neuropathology. Nature communications 13 (1) (2022)
Yongxiu Song, Bin Dai, Yong Wang, Yin Wang, Cong Liu, Pontus Gourdon, Lei Liu, Kaituo Wang, Mingdong Dong
Identifying Heterozipper β-Sheet in Twisted Amyloid Aggregation. Nano letters 22 (9) (2022)
Shengnan Zhang, Yi Zhu, Jinxia Lu, Zhenying Liu, Amanda G Lobato, Wen Zeng, Jiaqi Liu, Jiali Qiang, Shuyi Zeng, Yaoyang Zhang, Cong Liu, Jun Liu, Zhuohao He, Rong Grace Zhai, Dan Li
Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation-induced pathology. eLife 11 (2022)
Qi Wang, Zhouxian Li, Shenqing Zhang, Yichen Li, Yan Wang, Zheng Fang, Yanni Ma, Zhen Liu, Weibing Zhang, Dan Li, Cong Liu, Mingliang Ye
Global profiling of arginine dimethylation in regulating protein phase separation by a steric effect-based chemical-enrichment method. Proceedings of the National Academy of Sciences of the United States of America 119 (43) (2022)
Jun Li, JingFei Xie, Aljaž Godec, Keith R Weninger, Cong Liu, Jeremy C Smith, Liang Hong
Non-ergodicity of a globular protein extending beyond its functional timescale. Chemical science 13 (33) (2022)
Hao He, Wu Yang, Nan Su, Chuankai Zhang, Jianing Dai, Feng Han, Mahak Singhal, Wenjuan Bai, Xiaolan Zhu, Jing Zhu, Zhen Liu, Wencheng Xia, Xiaoting Liu, Chonghe Zhang, Kai Jiang, Wenhui Huang, Dan Chen, Zhaoyin Wang, Xueyang He, Frank Kirchhoff, Zhenyu Li, Cong Liu, Jingning Huan, Xiaohong Wang, Wu Wei, Jing Wang, Hellmut G Augustin, Junhao Hu
Activating NO-sGC crosstalk in the mouse vascular niche promotes vascular integrity and mitigates acute lung injury. The Journal of experimental medicine 220 (2) (2022)
Dan Li, Cong Liu
Conformational strains of pathogenic amyloid proteins in neurodegenerative diseases. Nature reviews. Neuroscience 23 (9) (2022)
Shan Lu, Jiaojiao Hu, Olubankole Aladesuyi Arogundade, Alexander Goginashvili, Sonia Vazquez-Sanchez, Jolene K Diedrich, Jinge Gu, Jacob Blum, Spencer Oung, Qiaozhen Ye, Haiyang Yu, John Ravits, Cong Liu, John Yates Iii, Don W Cleveland
Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition. Nature cell biology 24 (9) (2022)
Li-Qiang Wang, Yeyang Ma, Han-Ye Yuan, Kun Zhao, Mu-Ya Zhang, Qiang Wang, Xi Huang, Wen-Chang Xu, Bin Dai, Jie Chen, Dan Li, Delin Zhang, Zhengzhi Wang, Liangyu Zou, Ping Yin, Cong Liu, Yi Yang
Cryo-EM structure of an amyloid fibril formed by full-length human SOD1 reveals its conformational conversion. Nature communications 13 (1) (2022)
Shengnan Zhang, Yu-Qing Liu, Chunyu Jia, Yeh-Jun Lim, Guoqin Feng, Enquan Xu, Houfang Long, Yasuyoshi Kimura, Youqi Tao, Chunyu Zhao, Chuchu Wang, Zhenying Liu, Jin-Jian Hu, Meng-Rong Ma, Zhijun Liu, Lin Jiang, Dan Li, Ren-Xiao Wang, Valina L Dawson, Ted M Dawson, Yan-Mei Li, Xiaobo Mao, Cong Liu
Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America 118 (26) (2021)
Houfang Long, Weitong Zheng, Yang Liu, Yunpeng Sun, Kun Zhao, Zhenying Liu, Wencheng Xia, Shiran Lv, Zhengtao Liu, Dan Li, Kai-Wen He, Cong Liu
Wild-type α-synuclein inherits the structure and exacerbated neuropathology of E46K mutant fibril strain by cross-seeding. Proceedings of the National Academy of Sciences of the United States of America 118 (20) (2021)
Jinge Gu, Chen Wang, Rirong Hu, Yichen Li, Shengnan Zhang, Yunpeng Sun, Qiangqiang Wang, Dan Li, Yanshan Fang, Cong Liu
Hsp70 chaperones TDP-43 in dynamic, liquid-like phase and prevents it from amyloid aggregation. Cell research 31 (9) (2021)
Shasha Ye, Ziting Chen, Xia Zhang, Fangfang Li, Lijuan Guo, Xi-Miao Hou, Wen-Qiang Wu, Jian Wang, Cong Liu, Ke Zheng, Bo Sun
Proximal Single-Stranded RNA Destabilizes Human Telomerase RNA G-Quadruplex and Induces Its Distinct Conformers. The journal of physical chemistry letters 12 (13) (2021)
Dangliang Liu, Qijia Wei, Wencheng Xia, Changdong He, Qikai Zhang, Lu Huang, Xiaoya Wang, Yunpeng Sun, Yeyang Ma, Xiaohui Zhang, Yuan Wang, Xiaomeng Shi, Cong Liu, Suwei Dong
O-Glycosylation Induces Amyloid-β To Form New Fibril Polymorphs Vulnerable for Degradation. Journal of the American Chemical Society 143 (48) (2021)
Yunpeng Sun, Houfang Long, Wencheng Xia, Kun Wang, Xia Zhang, Bo Sun, Qin Cao, Yao-Yang Zhang, Bin Dai, Dan Li, Cong Liu
The hereditary mutation G51D unlocks a distinct fibril strain transmissible to wild-type α-synuclein. Nature communications 12 (1) (2021)
Dan Li, Cong Liu
Hierarchical chemical determination of amyloid polymorphs in neurodegenerative disease. Nature chemical biology 17 (3) (2021)
Li-Qiang Wang, Kun Zhao, Han-Ye Yuan, Xiang-Ning Li, Hai-Bin Dang, Yeyang Ma, Qiang Wang, Chen Wang, Yunpeng Sun, Jie Chen, Dan Li, Delin Zhang, Ping Yin, Cong Liu, Yi Yang
Genetic prion disease-related mutation E196K displays a novel amyloid fibril structure revealed by cryo-EM. Science advances 7 (37) (2021)
Xialian Wu, Yeyang Ma, Kun Zhao, Jing Zhang, Yunpeng Sun, Yichen Li, Xingqi Dong, Hong Hu, Jing Liu, Jian Wang, Xia Zhang, Bing Li, Huayi Wang, Dan Li, Bo Sun, Jun-Xia Lu, Cong Liu
The structure of a minimum amyloid fibril core formed by necroptosis-mediating RHIM of human RIPK3. Proceedings of the National Academy of Sciences of the United States of America 118 (14) (2021)
Yunpeng Sun, Kun Zhao, Wencheng Xia, Guoqin Feng, Jinge Gu, Yeyang Ma, Xinrui Gui, Xia Zhang, Yanshan Fang, Bo Sun, Renxiao Wang, Cong Liu, Dan Li
The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure. Nature communications 11 (1) (2020)
Kun Zhao, Yeh-Jun Lim, Zhenying Liu, Houfang Long, Yunpeng Sun, Jin-Jian Hu, Chunyu Zhao, Youqi Tao, Xing Zhang, Dan Li, Yan-Mei Li, Cong Liu
Parkinson's disease-related phosphorylation at Tyr39 rearranges α-synuclein amyloid fibril structure revealed by cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 117 (33) (2020)
Yunpeng Sun, Shouqiao Hou, Kun Zhao, Houfang Long, Zhenying Liu, Jing Gao, Yao-Yang Zhang, Xiao-Dong Su, Dan Li, Cong Liu
Cryo-EM structure of full-length α-synuclein amyloid fibril with Parkinson's disease familial A53T mutation. Cell research 30 (4) (2020)
Dan Li, Cong Liu
Structural Diversity of Amyloid Fibrils and Advances in Their Structure Determination. Biochemistry 59 (5) (2020)
Kun Zhao, Yaowang Li, Zhenying Liu, Houfang Long, Chunyu Zhao, Feng Luo, Yunpeng Sun, Youqi Tao, Xiao-Dong Su, Dan Li, Xueming Li, Cong Liu
Parkinson's disease associated mutation E46K of α-synuclein triggers the formation of a distinct fibril structure. Nature communications 11 (1) (2020)
Li-Qiang Wang, Kun Zhao, Han-Ye Yuan, Qiang Wang, Zeyuan Guan, Jing Tao, Xiang-Ning Li, Yunpeng Sun, Chuan-Wei Yi, Jie Chen, Dan Li, Delin Zhang, Ping Yin, Cong Liu, Yi Yang
Cryo-EM structure of an amyloid fibril formed by full-length human prion protein. Nature structural & molecular biology 27 (6) (2020)
Zhenying Liu, Shengnan Zhang, Jinge Gu, Yilun Tong, Yichen Li, Xinrui Gui, Houfang Long, Chuchu Wang, Chunyu Zhao, Jinxia Lu, Lin He, Ying Li, Zhijun Liu, Dan Li, Cong Liu
Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation. Nature structural & molecular biology 27 (4) (2020)
Xiaojuan Ma, Yi Zhu, Jinxia Lu, Jingfei Xie, Chong Li, Woo Shik Shin, Jiali Qiang, Jiaqi Liu, Shuai Dou, Yi Xiao, Chuchu Wang, Chunyu Jia, Houfang Long, Juntao Yang, Yanshan Fang, Lin Jiang, Yaoyang Zhang, Shengnan Zhang, Rong Grace Zhai, Cong Liu, Dan Li
Nicotinamide mononucleotide adenylyltransferase uses its NAD+ substrate-binding site to chaperone phosphorylated Tau. eLife 9 (2020)
Jinge Gu, Zhenying Liu, Shengnan Zhang, Yichen Li, Wencheng Xia, Chen Wang, Huaijiang Xiang, Zhijun Liu, Li Tan, Yanshan Fang, Cong Liu, Dan Li
Hsp40 proteins phase separate to chaperone the assembly and maintenance of membraneless organelles. Proceedings of the National Academy of Sciences of the United States of America 117 (49) (2020)
Chuchu Wang, Jia Tu, Shengnan Zhang, Bin Cai, Zhenying Liu, Shouqiao Hou, Qinglu Zhong, Xiao Hu, Wenbin Liu, Guo-Hui Li, Zhijun Liu, Lin He, Jiajie Diao, Zheng-Jiang Zhu, Dan Li, Cong Liu
Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly. Nature communications 11 (1) (2020)
Xinrui Gui, Feng Luo, Yichen Li, Heng Zhou, Zhenheng Qin, Zhenying Liu, Jinge Gu, Muyun Xie, Kun Zhao, Bin Dai, Woo Shik Shin, Jianhua He, Lin He, Lin Jiang, Minglei Zhao, Bo Sun, Xueming Li, Cong Liu, Dan Li
Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly. Nature communications 10 (1) (2019)
Jing Yu, Zaizhou Liu, Yuanyuan Liang, Feng Luo, Jie Zhang, Cuiping Tian, Alex Motzik, Mengmeng Zheng, Jingwu Kang, Guisheng Zhong, Cong Liu, Pengfei Fang, Min Guo, Ehud Razin, Jing Wang
Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in FcεRI-activated mast cells. Nature communications 10 (1) (2019)
Mengkui Cui, Xinyu Wang, Bolin An, Chen Zhang, Xinrui Gui, Ke Li, Yingfeng Li, Peng Ge, Junhu Zhang, Cong Liu, Chao Zhong
Exploiting mammalian low-complexity domains for liquid-liquid phase separation-driven underwater adhesive coatings. Science advances 5 (8) (2019)
Yongjia Duan, Aiying Du, Jinge Gu, Gang Duan, Chen Wang, Xinrui Gui, Zhiwei Ma, Beituo Qian, Xue Deng, Kai Zhang, Le Sun, Kuili Tian, Yaoyang Zhang, Hong Jiang, Cong Liu, Yanshan Fang
PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins. Cell research 29 (3) (2019)
Xiang Zhang, Shengnan Zhang, Li Zhang, Jinxia Lu, Chunyu Zhao, Feng Luo, Dan Li, Xueming Li, Cong Liu
Heat shock protein 104 (HSP104) chaperones soluble Tau via a mechanism distinct from its disaggregase activity. The Journal of biological chemistry 294 (13) (2019)
Shengnan Zhang, Chuchu Wang, Jinxia Lu, Xiaojuan Ma, Zhenying Liu, Dan Li, Zhijun Liu, Cong Liu
In-Cell NMR Study of Tau and MARK2 Phosphorylated Tau. International journal of molecular sciences 20 (1) (2018)
Yaowang Li, Chunyu Zhao, Feng Luo, Zhenying Liu, Xinrui Gui, Zhipu Luo, Xiang Zhang, Dan Li, Cong Liu, Xueming Li
Amyloid fibril structure of α-synuclein determined by cryo-electron microscopy. Cell research 28 (9) (2018)
Feng Luo, Xinrui Gui, Heng Zhou, Jinge Gu, Yichen Li, Xiangyu Liu, Minglei Zhao, Dan Li, Xueming Li, Cong Liu
Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation. Nature structural & molecular biology 25 (4) (2018)

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Cong Liu