Peter C Searson (Peter Searson)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 49

Top Topics

Cerebral Blood Flow

Endothelial Cells

Top Venues

Science translational medicine

Advanced healthcare materials

Fluids and barriers of the CNS

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Nan Zhao, Alexander F Pessell, Ninghao Zhu, Peter C Searson
Tissue-Engineered Microvessels: A Review of Current Engineering Strategies and Applications. Advanced healthcare materials 13 (21) (2024)
Nan Zhao, Alexander F Pessell, Ninghao Zhu, Peter C Searson
Tissue-Engineered Microvessels: A Review of Current Engineering Strategies and Applications. Advanced healthcare materials 13 (21) (2024)
Yi Dong, Blake A Johnson, Linhao Ruan, Maged Zeineldin, Tianhao Bi, Albert Z Liu, Sumana Raychaudhuri, Ian Chiu, Jin Zhu, Barbara Smith, Nan Zhao, Peter C Searson, Shigeki Watanabe, Mark Donowitz, Tatianna C Larman, Rong Li
Disruption of epithelium integrity by inflammation-associated fibroblasts through prostaglandin signaling. Science advances 10 (14) (2024)
Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Yi Dong, Blake A Johnson, Linhao Ruan, Maged Zeineldin, Tianhao Bi, Albert Z Liu, Sumana Raychaudhuri, Ian Chiu, Jin Zhu, Barbara Smith, Nan Zhao, Peter C Searson, Shigeki Watanabe, Mark Donowitz, Tatianna C Larman, Rong Li
Disruption of epithelium integrity by inflammation-associated fibroblasts through prostaglandin signaling. Science advances 10 (14) (2024)
Nan Zhao, Alexander F Pessell, Ninghao Zhu, Peter C Searson
Tissue-Engineered Microvessels: A Review of Current Engineering Strategies and Applications. Advanced healthcare materials (2024)
Nan Zhao, Alexander F Pessell, Ninghao Zhu, Peter C Searson
Tissue-Engineered Microvessels: A Review of Current Engineering Strategies and Applications. Advanced healthcare materials 13 (21) (2024)
Nan Zhao, Alexander F Pessell, Ninghao Zhu, Peter C Searson
Tissue-Engineered Microvessels: A Review of Current Engineering Strategies and Applications. Advanced healthcare materials (2024)
Yi Dong, Blake A Johnson, Linhao Ruan, Maged Zeineldin, Tianhao Bi, Albert Z Liu, Sumana Raychaudhuri, Ian Chiu, Jin Zhu, Barbara Smith, Nan Zhao, Peter C Searson, Shigeki Watanabe, Mark Donowitz, Tatianna C Larman, Rong Li
Disruption of epithelium integrity by inflammation-associated fibroblasts through prostaglandin signaling. Science advances 10 (14) (2024)
Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Yi Dong, Blake A Johnson, Linhao Ruan, Maged Zeineldin, Tianhao Bi, Albert Z Liu, Sumana Raychaudhuri, Ian Chiu, Jin Zhu, Barbara Smith, Nan Zhao, Peter C Searson, Shigeki Watanabe, Mark Donowitz, Tatianna C Larman, Rong Li
Disruption of epithelium integrity by inflammation-associated fibroblasts through prostaglandin signaling. Science advances 10 (14) (2024)
Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Yi Dong, Blake A Johnson, Linhao Ruan, Maged Zeineldin, Tianhao Bi, Albert Z Liu, Sumana Raychaudhuri, Ian Chiu, Jin Zhu, Barbara Smith, Nan Zhao, Peter C Searson, Shigeki Watanabe, Mark Donowitz, Tatianna C Larman, Rong Li
Disruption of epithelium integrity by inflammation-associated fibroblasts through prostaglandin signaling. Science advances 10 (14) (2024)
Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Nan Zhao, Alexander F Pessell, Ninghao Zhu, Peter C Searson
Tissue-Engineered Microvessels: A Review of Current Engineering Strategies and Applications. Advanced healthcare materials (2024)
Nan Zhao, Alexander F Pessell, Ninghao Zhu, Peter C Searson
Tissue-Engineered Microvessels: A Review of Current Engineering Strategies and Applications. Advanced healthcare materials 13 (21) (2024)
Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Christian Jorgensen, Martin B Ulmschneider, Peter C Searson
Modeling Substrate Entry into the P-Glycoprotein Efflux Pump at the Blood-Brain Barrier. Journal of medicinal chemistry (2023)
Christian Jorgensen, Martin B Ulmschneider, Peter C Searson
Modeling Substrate Entry into the P-Glycoprotein Efflux Pump at the Blood-Brain Barrier. Journal of medicinal chemistry 66 (24) (2023)
Peter C Searson
The Cancer Moonshot, the role of in vitro models, model accuracy, and the need for validation. Nature nanotechnology (2023)
Christian Jorgensen, Martin B Ulmschneider, Peter C Searson
Modeling Substrate Entry into the P-Glycoprotein Efflux Pump at the Blood-Brain Barrier. Journal of medicinal chemistry 66 (24) (2023)
Christian Jorgensen, Martin B Ulmschneider, Peter C Searson
Modeling Substrate Entry into the P-Glycoprotein Efflux Pump at the Blood-Brain Barrier. Journal of medicinal chemistry 66 (24) (2023)
Zheng Xu, Nicole Zahradka, Seyvonne Ip, Amirhossein Koneshloo, Ryan T Roemmich, Sameep Sehgal, Kristin B Highland, Peter C Searson
Evaluation of physical health status beyond daily step count using a wearable activity sensor. NPJ digital medicine 5 (1) (2022)
Zhaobin Guo, Nan Zhao, Tracy D Chung, Anjan Singh, Ikshu Pandey, Linus Wang, Xinyue Gu, Aisha Ademola, Raleigh M Linville, Utpal Pal, J Stephen Dumler, Peter C Searson
Visualization of the Dynamics of Invasion and Intravasation of the Bacterium That Causes Lyme Disease in a Tissue Engineered Dermal Microvessel Model. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2022)
Tracy D Chung, Raleigh M Linville, Zhaobin Guo, Robert Ye, Ria Jha, Gabrielle N Grifno, Peter C Searson
Effects of acute and chronic oxidative stress on the blood-brain barrier in 2D and 3D in vitro models. Fluids and barriers of the CNS 19 (1) (2022)
John J Jamieson, YingYu Lin, Nicholas Malloy, Daniel Soto, Peter C Searson, Sharon Gerecht
Hypoxia-induced blood-brain barrier dysfunction is prevented by pericyte-conditioned media via attenuated actomyosin contractility and claudin-5 stabilization. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36 (5) (2022)
Christian Jorgensen, Martin B Ulmschneider, Peter C Searson
Atomistic Model of Solute Transport across the Blood-Brain Barrier. ACS omega 7 (1) (2021)
Raleigh M Linville, Peter C Searson
Next-generation in vitro blood-brain barrier models: benchmarking and improving model accuracy. Fluids and barriers of the CNS 18 (1) (2021)
Dong-Hoon Choi, Grant B Kitchen, Mark T Jennings, Garry R Cutting, Peter C Searson
Out-of-clinic measurement of sweat chloride using a wearable sensor during low-intensity exercise. NPJ digital medicine 3 (2020)
Dong-Hoon Choi, Mark Gonzales, Grant B Kitchen, Dinh-Tuan Phan, Peter C Searson
A Capacitive Sweat Rate Sensor for Continuous and Real-Time Monitoring of Sweat Loss. ACS sensors 5 (12) (2020)
Raleigh M Linville, Jackson G DeStefano, Renée F Nerenberg, Gabrielle N Grifno, Robert Ye, Erin Gallagher, Peter C Searson
Long-Term Cryopreservation Preserves Blood-Brain Barrier Phenotype of iPSC-Derived Brain Microvascular Endothelial Cells and Three-Dimensional Microvessels. Molecular pharmaceutics 17 (9) (2020)
Raleigh M Linville, Jackson G DeStefano, Matt B Sklar, Chengyan Chu, Piotr Walczak, Peter C Searson
Modeling hyperosmotic blood-brain barrier opening within human tissue-engineered in vitro brain microvessels. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 40 (7) (2019)
Max I Bogorad, Jackson G DeStefano, Raleigh M Linville, Andrew D Wong, Peter C Searson
Cerebrovascular plasticity: Processes that lead to changes in the architecture of brain microvessels. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 39 (8) (2019)
Dong-Hoon Choi, Grant Kitchen, Ji Soo Kim, Yi Li, Kain Kim, In Cheol Jeong, Jane Nguyen, Kerry J Stewart, Scott L Zeger, Peter C Searson
Two Distinct Types of Sweat Profile in Healthy Subjects While Exercising at Constant Power Output Measured by a Wearable Sweat Sensor. Scientific reports 9 (1) (2019)
John J Jamieson, Raleigh M Linville, Yuan Yuan Ding, Sharon Gerecht, Peter C Searson
Role of iPSC-derived pericytes on barrier function of iPSC-derived brain microvascular endothelial cells in 2D and 3D. Fluids and barriers of the CNS 16 (1) (2019)
Gabrielle N Grifno, Alanna M Farrell, Raleigh M Linville, Diego Arevalo, Joo Ho Kim, Luo Gu, Peter C Searson
Tissue-engineered blood-brain barrier models via directed differentiation of human induced pluripotent stem cells. Scientific reports 9 (1) (2019)
Yukun Wang, Erin Gallagher, Christian Jorgensen, Evan P Troendle, Dan Hu, Peter C Searson, Martin B Ulmschneider
An experimentally validated approach to calculate the blood-brain barrier permeability of small molecules. Scientific reports 9 (1) (2019)
Johan Karlsson, Yuan Rui, Kristen L Kozielski, Amanda L Placone, Olivia Choi, Stephany Y Tzeng, Jayoung Kim, Jamal J Keyes, Max I Bogorad, Kathleen Gabrielson, Hugo Guerrero-Cazares, Alfredo Quiñones-Hinojosa, Peter C Searson, Jordan J Green
Engineered nanoparticles for systemic siRNA delivery to malignant brain tumours. Nanoscale 11 (42) (2019)
Moriah E Katt, Lakyn N Mayo, Shannon E Ellis, Vasiliki Mahairaki, Jeffrey D Rothstein, Linzhao Cheng, Peter C Searson
The role of mutations associated with familial neurodegenerative disorders on blood-brain barrier function in an iPSC model. Fluids and barriers of the CNS 16 (1) (2019)
Jackson G DeStefano, John J Jamieson, Raleigh M Linville, Peter C Searson
Benchmarking in vitro tissue-engineered blood-brain barrier models. Fluids and barriers of the CNS 15 (1) (2018)
Andrew D Wong, Luisa M Russell, Moriah E Katt, Peter C Searson
Chemotherapeutic Drug Delivery and Quantitative Analysis of Proliferation, Apoptosis, and Migration in a Tissue-Engineered Three-Dimensional Microvessel Model of the Tumor Microenvironment. ACS biomaterials science & engineering 5 (2) (2018)
Hyun-June Jang, Taein Lee, Jian Song, Luisa Russell, Hui Li, Jennifer Dailey, Peter C Searson, Howard E Katz
Electronic Cortisol Detection Using an Antibody-Embedded Polymer Coupled to a Field-Effect Transistor. ACS applied materials & interfaces 10 (19) (2018)
Jackson G DeStefano, Zinnia S Xu, Ashley J Williams, Nahom Yimam, Peter C Searson
Effect of shear stress on iPSC-derived human brain microvascular endothelial cells (dhBMECs). Fluids and barriers of the CNS 14 (1) (2017)
Chloe Kim, Peter C Searson
Detection of Plasmodium Lactate Dehydrogenase Antigen in Buffer Using Aptamer-Modified Magnetic Microparticles for Capture, Oligonucleotide-Modified Quantum Dots for Detection, and Oligonucleotide-Modified Gold Nanoparticles for Signal Amplification. Bioconjugate chemistry 28 (9) (2017)
Yu-Ja Huang, Paula Schiapparelli, Kristen Kozielski, Jordan Green, Emily Lavell, Hugo Guerrero-Cazares, Alfredo Quinones-Hinojosa, Peter C Searson
Electrophoresis of cell membrane heparan sulfate regulates galvanotaxis in glial cells. Journal of cell science 130 (15) (2017)
Chloe Kim, Gwendolyn Hoffmann, Peter C Searson
Integrated Magnetic Bead-Quantum Dot Immunoassay for Malaria Detection. ACS sensors 2 (6) (2017)
Dong-Hoon Choi, Jin Seob Kim, Garry R Cutting, Peter C Searson
Wearable Potentiometric Chloride Sweat Sensor: The Critical Role of the Salt Bridge. Analytical chemistry 88 (24) (2016)