Brett A McCray

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 19

Top Topics

Intellectual Disability

Chemotherapy Induced

Endothelial Cells

Top Venues

Science translational medicine

Brain : a journal of neurology

Nature communications

BioEssays : news and reviews in molecular, cellular and developmental biology

This page only lists publications with an associated author ORCID identifier.

Publications

Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Sarah H Berth, Linh Vo, Do Hoon Kwon, Tiffany Grider, Yasmine S Damayanti, Gage Kosmanopoulos, Andrew Fox, Alexander R Lau, Patrice Carr, Jack K Donohue, Maya Hoke, Simone Thomas, Chafic Karim, Alex J Fay, Ethan Meltzer, Thomas O Crawford, Rachelle Gaudet, Michael E Shy, Ute A Hellmich, Seok-Yong Lee, Charlotte J Sumner, Brett A McCray
Combined clinical, structural, and cellular studies discriminate pathogenic and benign TRPV4 variants. Brain : a journal of neurology (2024)
Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Gage Kosmanopoulos, Jack K Donohue, Maya Hoke, Simone Thomas, Margo A Peyton, Linh Vo, Thomas O Crawford, Reza Sadjadi, David N Herrmann, Sabrina W Yum, Mary M Reilly, Steven S Scherer, Richard S Finkel, Richard A Lewis, Davide Pareyson, Chiara Pisciotta, David Walk, Michael E Shy, Charlotte J Sumner, null null, Brett A McCray
TRPV4 neuromuscular disease registry highlights bulbar, skeletal and proximal limb manifestations. Brain : a journal of neurology (2024)
Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Gage Kosmanopoulos, Jack K Donohue, Maya Hoke, Simone Thomas, Margo A Peyton, Linh Vo, Thomas O Crawford, Reza Sadjadi, David N Herrmann, Sabrina W Yum, Mary M Reilly, Steven S Scherer, Richard S Finkel, Richard A Lewis, Davide Pareyson, Chiara Pisciotta, David Walk, Michael E Shy, Charlotte J Sumner, null null, Brett A McCray
TRPV4 neuromuscular disease registry highlights bulbar, skeletal and proximal limb manifestations. Brain : a journal of neurology (2024)
Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Reza Sadjadi, Vincent Picher-Martel, Jasper M Morrow, Daniel Thedens, Paul A DiCamillo, Brett A McCray, Davide Pareyson, David N Herrmann, Mary M Reilly, Jun Li, Diana Castro, Michael E Shy, null null
Clinical Characteristics of Charcot-Marie-Tooth Disease Type 4J. Neurology 103 (5) (2024)
Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C Saavedra-Rivera, Lingling Kong, Jennifer S Huh, Brett A McCray, William H Aisenberg, Aamir R Zuberi, Laurent Bogdanik, Cathleen M Lutz, Zhaozhu Qiu, Katharina A Quinlan, Peter C Searson, Charlotte J Sumner
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice. Science translational medicine 16 (748) (2024)
Benedikt Goretzki, Christoph Wiedemann, Brett A McCray, Stefan L Schäfer, Jasmin Jansen, Frederike Tebbe, Sarah-Ana Mitrovic, Julia Nöth, Ainara Claveras Cabezudo, Jack K Donohue, Cy Michael Jeffries, Wieland Steinchen, Florian Stengel, Charlotte J Sumner, Gerhard Hummer, Ute A Hellmich
Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity. Nature communications 14 (1) (2023)
Do Hoon Kwon, Feng Zhang, Brett A McCray, Meha Kumar, Jeremy M Sullivan, Charlotte J Sumner, Seok-Yong Lee
Structural insights into TRPV4-Rho GTPase signaling complex function and disease. bioRxiv : the preprint server for biology (2023)
Do Hoon Kwon, Feng Zhang, Brett A McCray, Shasha Feng, Meha Kumar, Jeremy M Sullivan, Wonpil Im, Charlotte J Sumner, Seok-Yong Lee
TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease. Nature communications 14 (1) (2023)
Tyler Rehbein, Tong Tong Wu, Simona Treidler, Davide Pareyson, Richard Lewis, Sabrina W Yum, Brett A McCray, Sindhu Ramchandren, Joshua Burns, Jun Li, Richard S Finkel, Steven S Scherer, Adriana P Rebelo, Michael E Shy, Mary M Reilly, David N Herrmann, null null
Neuropathy due to bi-allelic SH3TC2 variants: Genotype-phenotype correlation and natural history. Brain : a journal of neurology (2023)
Arens Taga, Margo A Peyton, Benedikt Goretzki, Thomas Q Gallagher, Ann Ritter, Amy Harper, Thomas O Crawford, Ute A Hellmich, Charlotte J Sumner, Brett A McCray
TRPV4 mutations causing mixed neuropathy and skeletal phenotypes result in severe gain of function. Annals of clinical and translational neurology 9 (3) (2022)
Anna M Bagnell, Charlotte J Sumner, Brett A McCray
TRPV4: A trigger of pathological RhoA activation in neurological disease. BioEssays : news and reviews in molecular, cellular and developmental biology 44 (6) (2022)
Brett A McCray, Erika Diehl, Jeremy M Sullivan, William H Aisenberg, Nicholas W Zaccor, Alexander R Lau, Dominick J Rich, Benedikt Goretzki, Ute A Hellmich, Thomas E Lloyd, Charlotte J Sumner
Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension. Nature communications 12 (1) (2021)
Brett A McCray, Steven S Scherer
Axonal Charcot-Marie-Tooth Disease: from Common Pathogenic Mechanisms to Emerging Treatment Opportunities. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics (2021)