Petra Scholze

Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 18

Top Topics

Molecular Docking

Induced Pluripotent Stem Cells

Top Venues

ACS chemical neuroscience

ACS chemical biology

Scientific reports

The European journal of neuroscience

This page only lists publications with an associated author ORCID identifier.

Publications

Ilayda Görgülü, Vinita Jagannath, Stephanie Pons, Filip Koniuszewski, Matthias Groszer, Uwe Maskos, Sigismund Huck, Petra Scholze
The human-specific nicotinic receptor subunit CHRFAM7A reduces α7 receptor function in human induced pluripotent stem cells-derived and transgenic mouse neurons. The European journal of neuroscience 60 (5) (2024)
Dishary Sharmin, Branka Divović, Xingjie Ping, Rok Cerne, Jodi L Smith, Sepideh Rezvanian, Prithu Mondal, Michelle Jean Meyer, Molly E Kiley, Leggy A Arnold, Md Yeunus Mian, Kamel Prasad Pandey, Xiaoming Jin, Jelena R Mitrović, Djordje Djorović, Arnold Lippa, James M Cook, Lalit K Golani, Petra Scholze, Miroslav M Savić, Jeffrey M Witkin
New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4 H -benzo[ f ]imidazo[1,5- a ][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High Oral Plasma and Brain Exposures, and Produces Antiseizure Efficacy in Mice, and Antiepileptogenic Activity in Neural Networks in Brain Slices from a Patient with Mesial Temporal Lobe Epilepsy. ACS chemical neuroscience (2024)
Dishary Sharmin, Branka Divović, Xingjie Ping, Rok Cerne, Jodi L Smith, Sepideh Rezvanian, Prithu Mondal, Michelle Jean Meyer, Molly E Kiley, Leggy A Arnold, Md Yeunus Mian, Kamel Prasad Pandey, Xiaoming Jin, Jelena R Mitrović, Djordje Djorović, Arnold Lippa, James M Cook, Lalit K Golani, Petra Scholze, Miroslav M Savić, Jeffrey M Witkin
New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4 H -benzo[ f ]imidazo[1,5- a ][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High Oral Plasma and Brain Exposures, and Produces Antiseizure Efficacy in Mice, and Antiepileptogenic Activity in Neural Networks in Brain Slices from a Patient with Mesial Temporal Lobe Epilepsy. ACS chemical neuroscience (2024)
Dishary Sharmin, Branka Divović, Xingjie Ping, Rok Cerne, Jodi L Smith, Sepideh Rezvanian, Prithu Mondal, Michelle Jean Meyer, Molly E Kiley, Leggy A Arnold, Md Yeunus Mian, Kamel Prasad Pandey, Xiaoming Jin, Jelena R Mitrović, Djordje Djorović, Arnold Lippa, James M Cook, Lalit K Golani, Petra Scholze, Miroslav M Savić, Jeffrey M Witkin
New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4 H -benzo[ f ]imidazo[1,5- a ][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High Oral Plasma and Brain Exposures, and Produces Antiseizure Efficacy in Mice, and Antiepileptogenic Activity in Neural Networks in Brain Slices from a Patient with Mesial Temporal Lobe Epilepsy. ACS chemical neuroscience 15 (3) (2024)
Ilayda Görgülü, Vinita Jagannath, Stephanie Pons, Filip Koniuszewski, Matthias Groszer, Uwe Maskos, Sigismund Huck, Petra Scholze
The human-specific nicotinic receptor subunit CHRFAM7A reduces α7 receptor function in human induced pluripotent stem cells-derived and transgenic mouse neurons. The European journal of neuroscience (2024)
Dishary Sharmin, Branka Divović, Xingjie Ping, Rok Cerne, Jodi L Smith, Sepideh Rezvanian, Prithu Mondal, Michelle Jean Meyer, Molly E Kiley, Leggy A Arnold, Md Yeunus Mian, Kamel Prasad Pandey, Xiaoming Jin, Jelena R Mitrović, Djordje Djorović, Arnold Lippa, James M Cook, Lalit K Golani, Petra Scholze, Miroslav M Savić, Jeffrey M Witkin
New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4 H -benzo[ f ]imidazo[1,5- a ][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High Oral Plasma and Brain Exposures, and Produces Antiseizure Efficacy in Mice, and Antiepileptogenic Activity in Neural Networks in Brain Slices from a Patient with Mesial Temporal Lobe Epilepsy. ACS chemical neuroscience 15 (3) (2024)
Dishary Sharmin, Branka Divović, Xingjie Ping, Rok Cerne, Jodi L Smith, Sepideh Rezvanian, Prithu Mondal, Michelle Jean Meyer, Molly E Kiley, Leggy A Arnold, Md Yeunus Mian, Kamel Prasad Pandey, Xiaoming Jin, Jelena R Mitrović, Djordje Djorović, Arnold Lippa, James M Cook, Lalit K Golani, Petra Scholze, Miroslav M Savić, Jeffrey M Witkin
New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4 H -benzo[ f ]imidazo[1,5- a ][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High Oral Plasma and Brain Exposures, and Produces Antiseizure Efficacy in Mice, and Antiepileptogenic Activity in Neural Networks in Brain Slices from a Patient with Mesial Temporal Lobe Epilepsy. ACS chemical neuroscience 15 (3) (2024)
Dishary Sharmin, Branka Divović, Xingjie Ping, Rok Cerne, Jodi L Smith, Sepideh Rezvanian, Prithu Mondal, Michelle Jean Meyer, Molly E Kiley, Leggy A Arnold, Md Yeunus Mian, Kamel Prasad Pandey, Xiaoming Jin, Jelena R Mitrović, Djordje Djorović, Arnold Lippa, James M Cook, Lalit K Golani, Petra Scholze, Miroslav M Savić, Jeffrey M Witkin
New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4 H -benzo[ f ]imidazo[1,5- a ][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High Oral Plasma and Brain Exposures, and Produces Antiseizure Efficacy in Mice, and Antiepileptogenic Activity in Neural Networks in Brain Slices from a Patient with Mesial Temporal Lobe Epilepsy. ACS chemical neuroscience (2024)
Konstantina Bampali, Filip Koniuszewski, Luca L Silva, Sabah Rehman, Florian D Vogel, Thomas Seidel, Petra Scholze, Florian Zirpel, Arthur Garon, Thierry Langer, Matthäus Willeit, Margot Ernst
Tricyclic antipsychotics and antidepressants can inhibit α5-containing GABA A receptors by two distinct mechanisms. British journal of pharmacology 179 (14) (2022)
Florian D Vogel, Martin Krenn, Dominik Sebastian Westphal, Elisabeth Graf, Matias Wagner, Steffen Leiz, Filip Koniuszewski, Maximilian Augé-Stock, Georg Kramer, Petra Scholze, Margot Ernst
A de novo missense variant in GABRA4 alters receptor function in an epileptic and neurodevelopmental phenotype. Epilepsia 63 (4) (2022)
Nils Ole Dalby, Christina Birkedahl Falk-Petersen, Ulrike Leurs, Petra Scholze, Jacob Krall, Bente Frølund, Petrine Wellendorph
Silencing of spontaneous activity at α4β1/3δ GABAA receptors in hippocampal granule cells reveals different ligand pharmacology. British journal of pharmacology 177 (17) (2020)
Maria Teresa Iorio, Florian Daniel Vogel, Filip Koniuszewski, Petra Scholze, Sabah Rehman, Xenia Simeone, Michael Schnürch, Marko D Mihovilovic, Margot Ernst
GABAA Receptor Ligands Often Interact with Binding Sites in the Transmembrane Domain and in the Extracellular Domain-Can the Promiscuity Code Be Cracked? International journal of molecular sciences 21 (1) (2020)
Xenia Simeone, Filip Koniuszewski, Markus Müllegger, Andreas Smetka, Friederike Steudle, Roshan Puthenkalam, Margot Ernst, Petra Scholze
A Benzodiazepine Ligand with Improved GABAA Receptor α5-Subunit Selectivity Driven by Interactions with Loop C. Molecular pharmacology 99 (1) (2020)
Friederike Steudle, Sabah Rehman, Konstantina Bampali, Xenia Simeone, Zsofia Rona, Erwin Hauser, Wolfgang M Schmidt, Petra Scholze, Margot Ernst
A novel de novo variant of GABRA1 causes increased sensitivity for GABA in vitro. Scientific reports 10 (1) (2020)
David C B Siebert, Marcus Wieder, Lydia Schlener, Petra Scholze, Stefan Boresch, Thierry Langer, Michael Schnürch, Marko D Mihovilovic, Lars Richter, Margot Ernst, Gerhard F Ecker
SAR-Guided Scoring Function and Mutational Validation Reveal the Binding Mode of CGS-8216 at the α1+/γ2- Benzodiazepine Site. Journal of chemical information and modeling 58 (8) (2018)
Alshaimaa A Elgarf, David C B Siebert, Friederike Steudle, Angelika Draxler, Guanguan Li, Shengming Huang, James M Cook, Margot Ernst, Petra Scholze
Different Benzodiazepines Bind with Distinct Binding Modes to GABAA Receptors. ACS chemical biology 13 (8) (2018)
David C B Siebert, Konstantina Bampali, Roshan Puthenkalam, Zdravko Varagic, Isabella Sarto-Jackson, Petra Scholze, Werner Sieghart, Marko D Mihovilovic, Michael Schnürch, Margot Ernst
Engineered Flumazenil Recognition Site Provides Mechanistic Insight Governing Benzodiazepine Modulation in GABAA Receptors. ACS chemical biology 13 (8) (2018)
Xenia Simeone, David C B Siebert, Konstantina Bampali, Zdravko Varagic, Marco Treven, Sabah Rehman, Jakob Pyszkowski, Raphael Holzinger, Friederike Steudle, Petra Scholze, Marko D Mihovilovic, Michael Schnürch, Margot Ernst
Molecular tools for GABAA receptors: High affinity ligands for β1-containing subtypes. Scientific reports 7 (1) (2017)