Philipp Holliger

ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 23

Top Venues

Nature chemistry

Proceedings of the National Academy of Sciences of the United States of America

eLife

RSC chemical biology

MRC Laboratory of Molecular Biology

This page only lists publications with an associated author ORCID identifier.

Affiliation History

MRC Laboratory of Molecular Biology

United Kingdom

Program Leader :: Protein and Nucleic Acid Chemistry (PNAC)

Publications

Ewan K S McRae, Christopher J K Wan, Emil L Kristoffersen, Kalinka Hansen, Edoardo Gianni, Isaac Gallego, Joseph F Curran, James Attwater, Philipp Holliger, Ebbe Sloth Andersen
Cryo-EM structure and functional landscape of an RNA polymerase ribozyme. Proceedings of the National Academy of Sciences of the United States of America 121 (3) (2024)
Ewan K S McRae, Christopher J K Wan, Emil L Kristoffersen, Kalinka Hansen, Edoardo Gianni, Isaac Gallego, Joseph F Curran, James Attwater, Philipp Holliger, Ebbe Sloth Andersen
Cryo-EM structure and functional landscape of an RNA polymerase ribozyme. Proceedings of the National Academy of Sciences of the United States of America 121 (3) (2024)
Ewan K S McRae, Christopher J K Wan, Emil L Kristoffersen, Kalinka Hansen, Edoardo Gianni, Isaac Gallego, Joseph F Curran, James Attwater, Philipp Holliger, Ebbe Sloth Andersen
Cryo-EM structure and functional landscape of an RNA polymerase ribozyme. Proceedings of the National Academy of Sciences of the United States of America 121 (3) (2024)
Ewan K S McRae, Christopher J K Wan, Emil L Kristoffersen, Kalinka Hansen, Edoardo Gianni, Isaac Gallego, Joseph F Curran, James Attwater, Philipp Holliger, Ebbe Sloth Andersen
Cryo-EM structure and functional landscape of an RNA polymerase ribozyme. Proceedings of the National Academy of Sciences of the United States of America 121 (3) (2024)
Ewan K S McRae, Christopher J K Wan, Emil L Kristoffersen, Kalinka Hansen, Edoardo Gianni, Isaac Gallego, Joseph F Curran, James Attwater, Philipp Holliger, Ebbe Sloth Andersen
Cryo-EM structure and functional landscape of an RNA polymerase ribozyme. Proceedings of the National Academy of Sciences of the United States of America 121 (3) (2024)
Peter Schofield, Alexander I Taylor, Jérôme Rihon, Cristian D Peña Martinez, Sacha Zinn, Charles-Alexandre Mattelaer, Jennifer Jackson, Gurpreet Dhaliwal, Guy Schepers, Piet Herdwijn, Eveline Lescrinier, Daniel Christ, Philipp Holliger
Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif. Nucleic acids research (2023)
Benjamin Thomas Porebski, Matthew Balmforth, Gareth Browne, Aidan Riley, Kiarash Jamali, Maximillian J L J Fürst, Mirko Velic, Andrew Buchanan, Ralph R Minter, Tristan Vaughan, Philipp Holliger
Rapid discovery of high-affinity antibodies via massively parallel sequencing, ribosome display and affinity screening. Nature biomedical engineering (2023)
Emil Laust Kristoffersen, Matthew Burman, Agnes Noy, Philipp Holliger
Rolling circle RNA synthesis catalyzed by RNA. eLife 11 (2022)
Alexander I Taylor, Philipp Holliger
On gene silencing by the X10-23 DNAzyme. Nature chemistry 14 (8) (2022)
Peiying Li, Philipp Holliger, Shunsuke Tagami
Hydrophobic-cationic peptides modulate RNA polymerase ribozyme activity by accretion. Nature communications 13 (1) (2022)
John R D Hervey, Niklas Freund, Gillian Houlihan, Gurpreet Dhaliwal, Philipp Holliger, Alexander I Taylor
Efficient synthesis and replication of diverse sequence libraries composed of biostable nucleic acid analogues. RSC chemical biology 3 (10) (2022)
Dennis Bong, Philipp Holliger, Chaoyong James Yang
Introduction to the themed collection on XNA xeno-nucleic acids. RSC chemical biology 3 (11) (2022)
Niklas Freund, Alexander I Taylor, Sebastian Arangundy-Franklin, Nithya Subramanian, Sew Peak Chew, Amy M Whitaker, Bret D Freudenthal, Mikhail Abramov, Piet Herdewijn, Philipp Holliger
A two-residue nascent-strand steric gate controls synthesis of 2'-O-methyl- and 2'-O-(2-methoxyethyl)-RNA. Nature chemistry (2022)
Alexander I Taylor, Christopher J K Wan, Maria J Donde, Sew Peak Chew, Philipp Holliger
A modular XNAzyme cleaves long, structured RNAs under physiological conditions and enables allele-specific gene silencing. Nature chemistry 14 (11) (2022)
Thomas W Christy, Catherine A Giannetti, Gillian Houlihan, Matthew J Smola, Greggory M Rice, Jian Wang, Nikolay V Dokholyan, Alain Laederach, Philipp Holliger, Kevin M Weeks
Direct Mapping of Higher-Order RNA Interactions by SHAPE-JuMP. Biochemistry 60 (25) (2021)
Camille Samson, Pierre Legrand, Mustafa Tekpinar, Jef Rozenski, Mikhail Abramov, Philipp Holliger, Vitor B Pinheiro, Piet Herdwijn, Marc Delarue
Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules 10 (12) (2020)
Gillian Houlihan, Sebastian Arangundy-Franklin, Benjamin Thomas Porebski, Nithya Subramanian, Alexander I Taylor, Philipp Holliger
Discovery and evolution of RNA and XNA reverse transcriptase function and fidelity. Nature chemistry 12 (8) (2020)
Kevin M Rose, Irani Alves Ferreira-Bravo, Min Li, Robert Craigie, Mark A Ditzler, Philipp Holliger, Jeffrey J DeStefano
Selection of 2'-Deoxy-2'-Fluoroarabino Nucleic Acid (FANA) Aptamers That Bind HIV-1 Integrase with Picomolar Affinity. ACS chemical biology 14 (10) (2019)
Sebastian Arangundy-Franklin, Alexander I Taylor, Benjamin Thomas Porebski, Vito Genna, Sew Peak-Chew, Alexandra Vaisman, Roger Woodgate, Modesto Orozco, Philipp Holliger
A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids. Nature chemistry 11 (6) (2019)
James Attwater, Aditya Raguram, Alexey S Morgunov, Edoardo Gianni, Philipp Holliger
Ribozyme-catalysed RNA synthesis using triplet building blocks. eLife 7 (2018)
Hannes Mutschler, Alexander I Taylor, Benjamin T Porebski, Alice Lightowlers, Gillian Houlihan, Mikhail Abramov, Piet Herdwijn, Philipp Holliger
Random-sequence genetic oligomer pools display an innate potential for ligation and recombination. eLife 7 (2018)
Shunsuke Tagami, James Attwater, Philipp Holliger
Simple peptides derived from the ribosomal core potentiate RNA polymerase ribozyme function. Nature chemistry 9 (4) (2017)
Gillian Houlihan, Sebastian Arangundy-Franklin, Philipp Holliger
Exploring the Chemistry of Genetic Information Storage and Propagation through Polymerase Engineering. Accounts of chemical research 50 (4) (2017)
Hannes Mutschler, Aniela Wochner, Philipp Holliger
Freeze-thaw cycles as drivers of complex ribozyme assembly. Nature chemistry 7 (6) (2015)

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Publication Activity (10 Years)

Top Topics

Top Venues

Philipp Holliger